-
1
-
-
0037267333
-
Validating survivin as a cancer therapeutic target
-
D.C. Altieri Validating survivin as a cancer therapeutic target Nat. Rev. Cancer 3 2003 46 54
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 46-54
-
-
Altieri, D.C.1
-
2
-
-
0037075232
-
Ansamycin antibiotics inhibit Akt activation and cyclin D expression in breast cancer cells that overexpress HER2
-
A.D. Basso, D.B. Solit, P.N. Munster, and N. Rosen Ansamycin antibiotics inhibit Akt activation and cyclin D expression in breast cancer cells that overexpress HER2 Oncogene 21 2002 1159 1166
-
(2002)
Oncogene
, vol.21
, pp. 1159-1166
-
-
Basso, A.D.1
Solit, D.B.2
Munster, P.N.3
Rosen, N.4
-
3
-
-
3242879188
-
"The stress of dying": The role of heat shock proteins in the regulation of apoptosis
-
H.M. Beere "The stress of dying": The role of heat shock proteins in the regulation of apoptosis J. Cell Sci. 117 2004 2641 2651
-
(2004)
J. Cell Sci.
, vol.117
, pp. 2641-2651
-
-
Beere, H.M.1
-
4
-
-
0029131395
-
The retro-inverso form of a homeobox-derived short peptide is rapidly internalised by cultured neurones: A new basis for an efficient intracellular delivery system
-
J. Brugidou, C. Legrand, J. Mery, and A. Rabie The retro-inverso form of a homeobox-derived short peptide is rapidly internalised by cultured neurones: A new basis for an efficient intracellular delivery system Biochem. Biophys. Res. Commun. 214 1995 685 693
-
(1995)
Biochem. Biophys. Res. Commun.
, vol.214
, pp. 685-693
-
-
Brugidou, J.1
Legrand, C.2
Mery, J.3
Rabie, A.4
-
5
-
-
0033551066
-
Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists
-
Y.N. Chen, S.K. Sharma, T.M. Ramsey, L. Jiang, M.S. Martin, K. Baker, P.D. Adams, K.W. Bair, and W.G. Kaelin Jr. Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists Proc. Natl. Acad. Sci. USA 96 1999 4325 4329
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 4325-4329
-
-
Chen, Y.N.1
Sharma, S.K.2
Ramsey, T.M.3
Jiang, L.4
Martin, M.S.5
Baker, K.6
Adams, P.D.7
Bair, K.W.8
Kaelin Jr., W.G.9
-
6
-
-
9644278114
-
Mitochondrial survivin inhibits apoptosis and promotes tumorigenesis
-
T. Dohi, E. Beltrami, N.R. Wall, J. Plescia, and D.C. Altieri Mitochondrial survivin inhibits apoptosis and promotes tumorigenesis J. Clin. Invest. 114 2004 1117 1127
-
(2004)
J. Clin. Invest.
, vol.114
, pp. 1117-1127
-
-
Dohi, T.1
Beltrami, E.2
Wall, N.R.3
Plescia, J.4
Altieri, D.C.5
-
7
-
-
0344270928
-
Regulation of survivin function by Hsp90
-
P. Fortugno, E. Beltrami, J. Plescia, J. Fontana, D. Pradhan, P.C. Marchisio, W.C. Sessa, and D.C. Altieri Regulation of survivin function by Hsp90 Proc. Natl. Acad. Sci. USA 100 2003 13791 13796
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 13791-13796
-
-
Fortugno, P.1
Beltrami, E.2
Plescia, J.3
Fontana, J.4
Pradhan, D.5
Marchisio, P.C.6
Sessa, W.C.7
Altieri, D.C.8
-
8
-
-
0346336791
-
Survivin regulates hematopoietic progenitor cell proliferation through p21WAF1/Cip1-dependent and -independent pathways
-
S. Fukuda, C.R. Mantel, and L.M. Pelus Survivin regulates hematopoietic progenitor cell proliferation through p21WAF1/Cip1-dependent and -independent pathways Blood 103 2004 120 127
-
(2004)
Blood
, vol.103
, pp. 120-127
-
-
Fukuda, S.1
Mantel, C.R.2
Pelus, L.M.3
-
10
-
-
0342378184
-
On the immunogenic properties of retro-inverso peptides. Total retro-inversion of T-cell epitopes causes a loss of binding to MHC II molecules
-
M. Herve, B. Maillere, G. Mourier, C. Texier, S. Leroy, and A. Menez On the immunogenic properties of retro-inverso peptides. Total retro-inversion of T-cell epitopes causes a loss of binding to MHC II molecules Mol. Immunol. 34 1997 157 163
-
(1997)
Mol. Immunol.
, vol.34
, pp. 157-163
-
-
Herve, M.1
Maillere, B.2
Mourier, G.3
Texier, C.4
Leroy, S.5
Menez, A.6
-
11
-
-
0033118355
-
Functional requirement of p23 and Hsp90 in telomerase complexes
-
S.E. Holt, D.L. Aisner, J. Baur, V.M. Tesmer, M. Dy, M. Ouellette, J.B. Trager, G.B. Morin, D.O. Toft, and J.W. Shay Functional requirement of p23 and Hsp90 in telomerase complexes Genes Dev. 13 1999 817 826
-
(1999)
Genes Dev.
, vol.13
, pp. 817-826
-
-
Holt, S.E.1
Aisner, D.L.2
Baur, J.3
Tesmer, V.M.4
Dy, M.5
Ouellette, M.6
Trager, J.B.7
Morin, G.B.8
Toft, D.O.9
Shay, J.W.10
-
12
-
-
0344418718
-
Effect of D-amino acid substitution on the stability, the secondary structure, and the activity of membrane-active peptide
-
S.Y. Hong, J.E. Oh, and K.H. Lee Effect of D-amino acid substitution on the stability, the secondary structure, and the activity of membrane-active peptide Biochem. Pharmacol. 58 1999 1775 1780
-
(1999)
Biochem. Pharmacol.
, vol.58
, pp. 1775-1780
-
-
Hong, S.Y.1
Oh, J.E.2
Lee, K.H.3
-
13
-
-
0043288724
-
Heat shock protein 90 as a molecular target for cancer therapeutics
-
J.S. Isaacs, W. Xu, and L. Neckers Heat shock protein 90 as a molecular target for cancer therapeutics Cancer Cell 3 2003 213 217
-
(2003)
Cancer Cell
, vol.3
, pp. 213-217
-
-
Isaacs, J.S.1
Xu, W.2
Neckers, L.3
-
14
-
-
0037169358
-
Apoptosis: A link between cancer genetics and chemotherapy
-
R.W. Johnstone, A.A. Ruefli, and S.W. Lowe Apoptosis: A link between cancer genetics and chemotherapy Cell 108 2002 153 164
-
(2002)
Cell
, vol.108
, pp. 153-164
-
-
Johnstone, R.W.1
Ruefli, A.A.2
Lowe, S.W.3
-
15
-
-
0142155259
-
Biological applications of protein transduction technology
-
P.S. Kabouridis Biological applications of protein transduction technology Trends Biotechnol. 21 2003 498 503
-
(2003)
Trends Biotechnol.
, vol.21
, pp. 498-503
-
-
Kabouridis, P.S.1
-
16
-
-
0141484615
-
A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors
-
A. Kamal, L. Thao, J. Sensintaffar, L. Zhang, M.F. Boehm, L.C. Fritz, and F.J. Burrows A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors Nature 425 2003 407 410
-
(2003)
Nature
, vol.425
, pp. 407-410
-
-
Kamal, A.1
Thao, L.2
Sensintaffar, J.3
Zhang, L.4
Boehm, M.F.5
Fritz, L.C.6
Burrows, F.J.7
-
17
-
-
3242893125
-
Quantum chemical calculations and mutational analysis suggest heat shock protein 90 catalyzes trans-cis isomerization of geldanamycin
-
Y.S. Lee, M.G. Marcu, and L. Neckers Quantum chemical calculations and mutational analysis suggest heat shock protein 90 catalyzes trans-cis isomerization of geldanamycin Chem. Biol. 11 2004 991 998
-
(2004)
Chem. Biol.
, vol.11
, pp. 991-998
-
-
Lee, Y.S.1
Marcu, M.G.2
Neckers, L.3
-
18
-
-
0032506524
-
Control of apoptosis and mitotic spindle checkpoint by survivin
-
F. Li, G. Ambrosini, E.Y. Chu, J. Plescia, S. Tognin, P.C. Marchisio, and D.C. Altieri Control of apoptosis and mitotic spindle checkpoint by survivin Nature 396 1998 580 584
-
(1998)
Nature
, vol.396
, pp. 580-584
-
-
Li, F.1
Ambrosini, G.2
Chu, E.Y.3
Plescia, J.4
Tognin, S.5
Marchisio, P.C.6
Altieri, D.C.7
-
19
-
-
0034711270
-
The heat shock protein 90 antagonist novobiocin interacts with a previously unrecognized ATP-binding domain in the carboxyl terminus of the chaperone
-
M.G. Marcu, A. Chadli, I. Bouhouche, M. Catelli, and L.M. Neckers The heat shock protein 90 antagonist novobiocin interacts with a previously unrecognized ATP-binding domain in the carboxyl terminus of the chaperone J. Biol. Chem. 275 2000 37181 37186
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 37181-37186
-
-
Marcu, M.G.1
Chadli, A.2
Bouhouche, I.3
Catelli, M.4
Neckers, L.M.5
-
20
-
-
0037352446
-
Structural and functional analysis of the middle segment of hsp90: Implications for ATP hydrolysis and client protein and cochaperone interactions
-
P. Meyer, C. Prodromou, B. Hu, C. Vaughan, S.M. Roe, B. Panaretou, P.W. Piper, and L.H. Pearl Structural and functional analysis of the middle segment of hsp90: Implications for ATP hydrolysis and client protein and cochaperone interactions Mol. Cell 11 2003 647 658
-
(2003)
Mol. Cell
, vol.11
, pp. 647-658
-
-
Meyer, P.1
Prodromou, C.2
Hu, B.3
Vaughan, C.4
Roe, S.M.5
Panaretou, B.6
Piper, P.W.7
Pearl, L.H.8
-
21
-
-
0034674783
-
Stepwise assembly of a glucocorticoid receptor.hsp90 heterocomplex resolves two sequential ATP-dependent events involving first hsp70 and then hsp90 in opening of the steroid binding pocket
-
Y. Morishima, P.J. Murphy, D.P. Li, E.R. Sanchez, and W.B. Pratt Stepwise assembly of a glucocorticoid receptor.hsp90 heterocomplex resolves two sequential ATP-dependent events involving first hsp70 and then hsp90 in opening of the steroid binding pocket J. Biol. Chem. 275 2000 18054 18060
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 18054-18060
-
-
Morishima, Y.1
Murphy, P.J.2
Li, D.P.3
Sanchez, E.R.4
Pratt, W.B.5
-
22
-
-
11644261806
-
Automated docking using a lamarckian genetic algorithm and empirical binding free energy function
-
G.M. Morris, D.S. Goodsell, R.S. Halliday, R. Huey, W.E. Hart, R.K. Belew, and A.J. Olson Automated docking using a lamarckian genetic algorithm and empirical binding free energy function J Comp Chem 19 1998 1639 1662
-
(1998)
J Comp Chem
, vol.19
, pp. 1639-1662
-
-
Morris, G.M.1
Goodsell, D.S.2
Halliday, R.S.3
Huey, R.4
Hart, W.E.5
Belew, R.K.6
Olson, A.J.7
-
23
-
-
0033635269
-
Crystal structure and mutagenic analysis of the inhibitor-of-apoptosis protein survivin
-
S.W. Muchmore, J. Chen, C. Jakob, D. Zakula, E.D. Matayoshi, W. Wu, H. Zhang, F. Li, S.C. Ng, and D.C. Altieri Crystal structure and mutagenic analysis of the inhibitor-of-apoptosis protein survivin Mol. Cell 6 2000 173 182
-
(2000)
Mol. Cell
, vol.6
, pp. 173-182
-
-
Muchmore, S.W.1
Chen, J.2
Jakob, C.3
Zakula, D.4
Matayoshi, E.D.5
Wu, W.6
Zhang, H.7
Li, F.8
Ng, S.C.9
Altieri, D.C.10
-
25
-
-
0034584880
-
STI571: An inhibitor of the BCR-ABL tyrosine kinase for the treatment of chronic myelogenous leukaemia
-
M.E. O'Dwyer, and B.J. Druker STI571: An inhibitor of the BCR-ABL tyrosine kinase for the treatment of chronic myelogenous leukaemia Lancet Oncol. 1 2000 207 211
-
(2000)
Lancet Oncol.
, vol.1
, pp. 207-211
-
-
O'Dwyer, M.E.1
Druker, B.J.2
-
26
-
-
3543092021
-
Pathways of apoptotic and non-apoptotic death in tumour cells
-
H. Okada, and T.W. Mak Pathways of apoptotic and non-apoptotic death in tumour cells Nat. Rev. Cancer 4 2004 592 603
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 592-603
-
-
Okada, H.1
Mak, T.W.2
-
27
-
-
2342624080
-
EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
-
J.G. Paez, P.A. Janne, J.C. Lee, S. Tracy, H. Greulich, S. Gabriel, P. Herman, F.J. Kaye, N. Lindeman, and T.J. Boggon EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy Science 304 2004 1497 1500
-
(2004)
Science
, vol.304
, pp. 1497-1500
-
-
Paez, J.G.1
Janne, P.A.2
Lee, J.C.3
Tracy, S.4
Greulich, H.5
Gabriel, S.6
Herman, P.7
Kaye, F.J.8
Lindeman, N.9
Boggon, T.J.10
-
28
-
-
0035227317
-
A retro-inverso peptide homologous to helix 1 of c-Myc is a potent and specific inhibitor of proliferation in different cellular systems
-
M.P. Pescarolo, L. Bagnasco, D. Malacarne, A. Melchiori, P. Valente, E. Millo, S. Bruno, S. Basso, and S. Parodi A retro-inverso peptide homologous to helix 1 of c-Myc is a potent and specific inhibitor of proliferation in different cellular systems FASEB J. 15 2001 31 33
-
(2001)
FASEB J.
, vol.15
, pp. 31-33
-
-
Pescarolo, M.P.1
Bagnasco, L.2
Malacarne, D.3
Melchiori, A.4
Valente, P.5
Millo, E.6
Bruno, S.7
Basso, S.8
Parodi, S.9
-
29
-
-
0348019096
-
Full-Length Dominant-Negative Survivin for Cancer Immunotherapy
-
V. Pisarev, B. Yu, R. Salup, S. Sherman, D.C. Altieri, and D.I. Gabrilovich Full-Length Dominant-Negative Survivin for Cancer Immunotherapy Clin. Cancer Res. 9 2003 6523 6533
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 6523-6533
-
-
Pisarev, V.1
Yu, B.2
Salup, R.3
Sherman, S.4
Altieri, D.C.5
Gabrilovich, D.I.6
-
30
-
-
0742269688
-
The Mechanism of Hsp90 regulation by the protein kinase-specific cochaperone p50(cdc37)
-
S.M. Roe, M.M. Ali, P. Meyer, C.K. Vaughan, B. Panaretou, P.W. Piper, C. Prodromou, and L.H. Pearl The Mechanism of Hsp90 regulation by the protein kinase-specific cochaperone p50(cdc37) Cell 116 2004 87 98
-
(2004)
Cell
, vol.116
, pp. 87-98
-
-
Roe, S.M.1
Ali, M.M.2
Meyer, P.3
Vaughan, C.K.4
Panaretou, B.5
Piper, P.W.6
Prodromou, C.7
Pearl, L.H.8
-
32
-
-
0037386258
-
Cytoprotective membrane-permeable peptides designed from the Bax-binding domain of Ku70
-
M. Sawada, P. Hayes, and S. Matsuyama Cytoprotective membrane-permeable peptides designed from the Bax-binding domain of Ku70 Nat. Cell Biol. 5 2003 352 357
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 352-357
-
-
Sawada, M.1
Hayes, P.2
Matsuyama, S.3
-
34
-
-
0031005361
-
Crystal structure of an Hsp90-geldanamycin complex: Targeting of a protein chaperone by an antitumor agent
-
C.E. Stebbins, A.A. Russo, C. Schneider, N. Rosen, F.U. Hartl, and N.P. Pavletich Crystal structure of an Hsp90-geldanamycin complex: Targeting of a protein chaperone by an antitumor agent Cell 89 1997 239 250
-
(1997)
Cell
, vol.89
, pp. 239-250
-
-
Stebbins, C.E.1
Russo, A.A.2
Schneider, C.3
Rosen, N.4
Hartl, F.U.5
Pavletich, N.P.6
-
35
-
-
0347917093
-
Cell-cycle targeted therapies
-
C. Swanton Cell-cycle targeted therapies Lancet Oncol. 5 2004 27 36
-
(2004)
Lancet Oncol.
, vol.5
, pp. 27-36
-
-
Swanton, C.1
-
36
-
-
10744221485
-
In vivo activation of the p53 pathway by small-molecule antagonists of MDM2
-
L.T. Vassilev, B.T. Vu, B. Graves, D. Carvajal, F. Podlaski, Z. Filipovic, N. Kong, U. Kammlott, C. Lukacs, and C. Klein In vivo activation of the p53 pathway by small-molecule antagonists of MDM2 Science 303 2004 844 848
-
(2004)
Science
, vol.303
, pp. 844-848
-
-
Vassilev, L.T.1
Vu, B.T.2
Graves, B.3
Carvajal, D.4
Podlaski, F.5
Filipovic, Z.6
Kong, N.7
Kammlott, U.8
Lukacs, C.9
Klein, C.10
-
37
-
-
0033923368
-
Structure of the human anti-apoptotic protein survivin reveals a dimeric arrangement
-
M.A. Verdecia, H. Huang, E. Dutil, D.A. Kaiser, T. Hunter, and J.P. Noel Structure of the human anti-apoptotic protein survivin reveals a dimeric arrangement Nat. Struct. Biol. 7 2000 602 608
-
(2000)
Nat. Struct. Biol.
, vol.7
, pp. 602-608
-
-
Verdecia, M.A.1
Huang, H.2
Dutil, E.3
Kaiser, D.A.4
Hunter, T.5
Noel, J.P.6
-
38
-
-
4043181214
-
Cancer genes and the pathways they control
-
B. Vogelstein, and K.W. Kinzler Cancer genes and the pathways they control Nat. Med. 10 2004 789 799
-
(2004)
Nat. Med.
, vol.10
, pp. 789-799
-
-
Vogelstein, B.1
Kinzler, K.W.2
-
40
-
-
0035939668
-
Hsp90: A specialized but essential protein-folding tool
-
J.C. Young, I. Moarefi, and F.U. Hartl Hsp90: A specialized but essential protein-folding tool J. Cell Biol. 154 2001 267 273
-
(2001)
J. Cell Biol.
, vol.154
, pp. 267-273
-
-
Young, J.C.1
Moarefi, I.2
Hartl, F.U.3
|