Intracellular Delivery of Bioactive Peptides to RBL-2H3 Cells Induces β-Hexosaminidase Secretion and Phospholipase D Activation

ChemBioChem

Volumn 4, Issue 12, 2003, Pages 1312-1316

  Howl, John ^a   Jones, Sarah ^a   Farquhar, Michelle ^a  

^a UNIVERSITY OF WOLVERHAMPTON   (United Kingdom)

Author keywords

Enzymes; Mast cells; Peptidomimetics; Secretion; Transportan

Indexed keywords

3 [8 [(DIMETHYLAMINO)METHYL] 6,7,8,9 TETRAHYDROPYRIDO[1,2 A]INDOL 10 YL] 4 (1 METHYL 1H INDOL 3 YL) 1H PYRROLE 2,5 DIONE; ALCOHOL; BETA N ACETYLHEXOSAMINIDASE; CALCIUM ION; CANNABINOID 1 RECEPTOR; CANNABINOID RECEPTOR; CELL PROTEIN; CHIMERIC PROTEIN; GALANIN DERIVATIVE; ISOPROTEIN; PHOSPHOLIPASE D; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; RAB PROTEIN; TRANSPORTAN 10; TRANSPORTAN 10 C1; TRANSPORTAN 10 C2; TRANSPORTAN 10 C3; TRANSPORTAN 10 C4; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHIMERA; CONTROLLED STUDY; CYTOPLASM; DOWN REGULATION; DRUG ACTIVITY; DRUG EFFICACY; ENZYME ACTIVATION; ENZYME RELEASE; INTRACELLULAR TRANSPORT; MAST CELL; MEMBRANE FUSION; NONHUMAN; PEPTIDE ANALYSIS; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RAT; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMALS; BETA-N-ACETYLHEXOSAMINIDASE; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; GLYCEROPHOSPHOLIPIDS; MAST CELLS; MOLECULAR SEQUENCE DATA; PEPTIDES; PHOSPHOLIPASE D; PROTEIN KINASE C; RAB3A GTP-BINDING PROTEIN; RATS; RECEPTOR, CANNABINOID, CB1; RECOMBINANT FUSION PROTEINS;

ANIMALIA;

EID: 0346157097     PISSN: 14394227     EISSN: None     Source Type: Journal    
DOI: 10.1002/cbic.200300694     Document Type: Article

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