-
1
-
-
77956408842
-
Outcomes for children and adolescents with cancer: Challenges for the twenty-first century
-
Smith MA, Seibel NL, Altekruse SF, Ries LA, Melbert DL, O'Leary M, Smith FO, and Reaman GH (2010). Outcomes for children and adolescents with cancer: challenges for the twenty-first century. J Clin Oncol 28, 2625-2634.
-
(2010)
J Clin Oncol
, vol.28
, pp. 2625-2634
-
-
Smith, M.A.1
Seibel, N.L.2
Altekruse, S.F.3
Ries, L.A.4
Melbert, D.L.5
O'Leary, M.6
Smith, F.O.7
Reaman, G.H.8
-
3
-
-
77953396751
-
New anti-angiogenic strategies in pediatric solid malignancies: Agents and biomarkers of a near future
-
Taylor M, Rössler J, Geoerger B, Vassal G, and Farace F (2010). New anti-angiogenic strategies in pediatric solid malignancies: agents and biomarkers of a near future. Expert Opin Investig Drugs 19, 859-874.
-
(2010)
Expert Opin Investig Drugs
, vol.19
, pp. 859-874
-
-
Taylor, M.1
Rössler, J.2
Geoerger, B.3
Vassal, G.4
Farace, F.5
-
4
-
-
2942615257
-
The anti-angiogenic basis of metronomic chemotherapy
-
Kerbel RS and Kamen BA (2004). The anti-angiogenic basis of metronomic chemotherapy. Nat Rev Cancer 4, 423-436.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 423-436
-
-
Kerbel, R.S.1
Kamen, B.A.2
-
5
-
-
33745291938
-
Metronomic dosing of chemotherapy: Applications in pediatric oncology
-
Stempak D, Seely D, and Baruchel S (2006). Metronomic dosing of chemotherapy: applications in pediatric oncology. Cancer Invest 24, 432-443.
-
(2006)
Cancer Invest
, vol.24
, pp. 432-443
-
-
Stempak, D.1
Seely, D.2
Baruchel, S.3
-
6
-
-
84872084645
-
Metronomic oral topotecan prolongs survival and reduces liver metastasis in improved pre-clinical orthotopic and adjuvant therapy colon cancer models
-
Hackl C, Man S, Francia G, Milsom C, Xu P, and Kerbel RS (2013). Metronomic oral topotecan prolongs survival and reduces liver metastasis in improved pre-clinical orthotopic and adjuvant therapy colon cancer models. Gut 62, 259-271.
-
(2013)
Gut
, vol.62
, pp. 259-271
-
-
Hackl, C.1
Man, S.2
Francia, G.3
Milsom, C.4
Xu, P.5
Kerbel, R.S.6
-
7
-
-
77955172181
-
Metronomic chemotherapy: New rationale for new directions
-
Pasquier E, Kavallaris M, and André N (2010). Metronomic chemotherapy: new rationale for new directions. Nat Rev Clin Oncol 7, 455-465.
-
(2010)
Nat Rev Clin Oncol
, vol.7
, pp. 455-465
-
-
Pasquier, E.1
Kavallaris, M.2
André, N.3
-
8
-
-
58149391392
-
Topotecan enhances immune clearance of gliomas
-
Wei J, DeAngulo G, Sun W, Hussain SF, Vasquez H, Jordan J, Weinberg J, Wolff J, Koshkina N, and Heimberger AB (2009). Topotecan enhances immune clearance of gliomas. Cancer Immunol Immunother 58, 259-270.
-
(2009)
Cancer Immunol Immunother
, vol.58
, pp. 259-270
-
-
Wei, J.1
Deangulo, G.2
Sun, W.3
Hussain, S.F.4
Vasquez, H.5
Jordan, J.6
Weinberg, J.7
Wolff, J.8
Koshkina, N.9
Heimberger, A.B.10
-
9
-
-
84857789296
-
The secret ally: Immunostimulation by anticancer drugs
-
Galluzzi L, Senovilla L, Zitvogel L, and Kroemer G (2012). The secret ally: immunostimulation by anticancer drugs. Nat Rev Drug Discov 3, 215-233.
-
(2012)
Nat Rev Drug Discov
, vol.3
, pp. 215-233
-
-
Galluzzi, L.1
Senovilla, L.2
Zitvogel, L.3
Kroemer, G.4
-
10
-
-
0034087691
-
Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained tumor regression without overt toxicity
-
Klement G, Baruchel S, Rak J, Man S, Clark K, Hicklin DJ, Bohlen P, and Kerbel RS (2000). Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained tumor regression without overt toxicity. J Clin Invest 105, R15-R24.
-
(2000)
J Clin Invest
, vol.105
-
-
Klement, G.1
Baruchel, S.2
Rak, J.3
Man, S.4
Clark, K.5
Hicklin, D.J.6
Bohlen, P.7
Kerbel, R.S.8
-
11
-
-
84872425530
-
HIF-1α activation mediates resistance to anti-angiogenic therapy in neuro-blastoma xenografts
-
Hartwich J, Orr WS, Ng CY, Spence Y, Morton C, and Davidoff AM (2013). HIF-1α activation mediates resistance to anti-angiogenic therapy in neuro-blastoma xenografts. J Pediatr Surg 48, 39-46.
-
(2013)
J Pediatr Surg
, vol.48
, pp. 39-46
-
-
Hartwich, J.1
Orr, W.S.2
Ng, C.Y.3
Spence, Y.4
Morton, C.5
Davidoff, A.M.6
-
12
-
-
77954595880
-
Metronomic gemcitabine in combination with sunitinib inhibits multisite metastasis and increases survival in an orthotopic model of pancreatic cancer
-
Tran Cao HS, Bouvet M, Kaushal S, Keleman A, Romney E, Kim G, Fruehauf J, Imagawa DK, Hoffman RM, and Katz MH (2010). Metronomic gemcitabine in combination with sunitinib inhibits multisite metastasis and increases survival in an orthotopic model of pancreatic cancer. Mol Cancer Ther 9, 2068-2078.
-
(2010)
Mol Cancer Ther
, vol.9
, pp. 2068-2078
-
-
Tran, C.H.S.1
Bouvet, M.2
Kaushal, S.3
Keleman, A.4
Romney, E.5
Kim, G.6
Fruehauf, J.7
Imagawa, D.K.8
Hoffman, R.M.9
Katz, M.H.10
-
13
-
-
84873080485
-
Thrombospondin-1 and pigment epithelium-derived factor enhance responsiveness of KM12 colon tumor to metronomic cyclophosphamide but have disparate effects on tumor metastasis
-
Jia L and Waxman DJ (2013). Thrombospondin-1 and pigment epithelium-derived factor enhance responsiveness of KM12 colon tumor to metronomic cyclophosphamide but have disparate effects on tumor metastasis. Cancer Lett 330, 241-249.
-
(2013)
Cancer Lett
, vol.330
, pp. 241-249
-
-
Jia, L.1
Waxman, D.J.2
-
14
-
-
84863445509
-
Enhanced anti-tumor and anti-angiogenic effects of metronomic cyclophosphamide combined with Endostar in a xenograft model of human lung cancer
-
Wang R, Qin S, Chen Y, Li Y, Chen C, Wang Z, Zheng R, and Wu Q (2012). Enhanced anti-tumor and anti-angiogenic effects of metronomic cyclophosphamide combined with Endostar in a xenograft model of human lung cancer. Oncol Rep 28, 439-445.
-
(2012)
Oncol Rep
, vol.28
, pp. 439-445
-
-
Wang, R.1
Qin, S.2
Chen, Y.3
Li, Y.4
Chen, C.5
Wang, Z.6
Zheng, R.7
Wu, Q.8
-
15
-
-
80054688412
-
The PACOVAR-trial: A phase I/II study of pazopanib (GW786034) and cyclophosphamide in patients with platinum-resistant recurrent, pre-treated ovarian cancer
-
Eichbaum M, Mayer C, Eickhoff R, Bischofs E, Gebauer G, Fehm T, Lenz F, Fricke HC, Solomayer E, Fersis N, et al. (2011). The PACOVAR-trial: a phase I/II study of pazopanib (GW786034) and cyclophosphamide in patients with platinum-resistant recurrent, pre-treated ovarian cancer. BMC Cancer 20, 453.
-
(2011)
BMC Cancer
, vol.20
, pp. 453
-
-
Eichbaum, M.1
Mayer, C.2
Eickhoff, R.3
Bischofs, E.4
Gebauer, G.5
Fehm, T.6
Lenz, F.7
Fricke, H.C.8
Solomayer, E.9
Fersis, N.10
-
16
-
-
54449099774
-
Metronomic cyclophosphamide and capecitabine combined with bevacizumab in advanced breast cancer
-
Dellapasqua S, Bertolini F, Bagnardi V, Campagnoli E, Scarano E, Torrisi R, Shaked Y, Mancuso P, Goldhirsch A, Rocca A, et al. (2008). Metronomic cyclophosphamide and capecitabine combined with bevacizumab in advanced breast cancer. J Clin Oncol 26, 4899-4905.
-
(2008)
J Clin Oncol
, vol.26
, pp. 4899-4905
-
-
Dellapasqua, S.1
Bertolini, F.2
Bagnardi, V.3
Campagnoli, E.4
Scarano, E.5
Torrisi, R.6
Shaked, Y.7
Mancuso, P.8
Goldhirsch, A.9
Rocca, A.10
-
17
-
-
84861111904
-
Metronomic chemotherapy combined with bevacizumab and erlotinib in patients with metastatic HER2-negative breast cancer: Clinical and biological activity
-
Montagna E, Cancello G, Bagnardi V, Pastrello D, Dellapasqua S, Perri G, Viale G, Veronesi P, Luini A, Intra M, et al. (2012). Metronomic chemotherapy combined with bevacizumab and erlotinib in patients with metastatic HER2-negative breast cancer: clinical and biological activity. Clin Breast Cancer 12, 207-214.
-
(2012)
Clin Breast Cancer
, vol.12
, pp. 207-214
-
-
Montagna, E.1
Cancello, G.2
Bagnardi, V.3
Pastrello, D.4
Dellapasqua, S.5
Perri, G.6
Viale, G.7
Veronesi, P.8
Luini, A.9
Intra, M.10
-
18
-
-
37849035249
-
Phase II clinical trial of bevacizumab and low-dose metronomic oral cyclophosphamide in recurrent ovarian cancer: A trial of the California, Chicago, and Princess Margaret Hospital phase II consortia
-
Garcia AA, Hirte H, Fleming G, Yang D, Tsao-Wei DD, Roman L, Groshen S, Swenson S, Markland F, Gandara D, et al. (2008). Phase II clinical trial of bevacizumab and low-dose metronomic oral cyclophosphamide in recurrent ovarian cancer: a trial of the California, Chicago, and Princess Margaret Hospital phase II consortia. J Clin Oncol 26, 76-82.
-
(2008)
J Clin Oncol
, vol.26
, pp. 76-82
-
-
Garcia, A.A.1
Hirte, H.2
Fleming, G.3
Yang, D.4
Tsao-Wei, D.D.5
Roman, L.6
Groshen, S.7
Swenson, S.8
Markland, F.9
Gandara, D.10
-
19
-
-
33751218313
-
A pilot pharmacokinetic and antiangiogenic biomarker study of celecoxib and low-dose metronomic vinblastine or cyclophosphamide in pediatric recurrent solid tumors
-
Stempak D, Gammon J, Halton J, Moghrabi A, Koren G, and Baruchel S (2006). A pilot pharmacokinetic and antiangiogenic biomarker study of celecoxib and low-dose metronomic vinblastine or cyclophosphamide in pediatric recurrent solid tumors. J Pediatr Hematol Oncol 28, 720-728.
-
(2006)
J Pediatr Hematol Oncol
, vol.28
, pp. 720-728
-
-
Stempak, D.1
Gammon, J.2
Halton, J.3
Moghrabi, A.4
Koren, G.5
Baruchel, S.6
-
20
-
-
84872448128
-
A pilot study of low-dose anti-angiogenic chemotherapy in combination with standard multi-agent chemotherapy for patients with newly diagnosed metastatic Ewing sarcoma family of tumors: A Children's Oncology Group (COG) phase II study NCT00061893
-
Felgenhauer JL, Nieder ML, Krailo MD, Bernstein ML, Henry DW, Malkin D, Baruchel S, Chuba PJ, Sailer SL, Brown K, et al. (2013). A pilot study of low-dose anti-angiogenic chemotherapy in combination with standard multi-agent chemotherapy for patients with newly diagnosed metastatic Ewing sarcoma family of tumors: a Children's Oncology Group (COG) phase II study NCT00061893. Pediatr Blood Cancer 60, 409-414.
-
(2013)
Pediatr Blood Cancer
, vol.60
, pp. 409-414
-
-
Felgenhauer, J.L.1
Nieder, M.L.2
Krailo, M.D.3
Bernstein, M.L.4
Henry, D.W.5
Malkin, D.6
Baruchel, S.7
Chuba, P.J.8
Sailer, S.L.9
Brown, K.10
-
21
-
-
79960303699
-
Moving forward with metronomic chemotherapy: Meeting report of the 2nd International Workshop on Metronomic and Anti-Angiogenic Chemotherapy in Paediatric Oncology
-
Pasquier E, Kieran MW, Sterba J, Shaked Y, Baruchel S, Oberlin O, Kivivuori MS, Peyrl A, Diawarra M, Casanova M, et al. (2011). Moving forward with metronomic chemotherapy: meeting report of the 2nd International Workshop on Metronomic and Anti-Angiogenic Chemotherapy in Paediatric Oncology. Transl Oncol 4, 203-211.
-
(2011)
Transl Oncol
, vol.4
, pp. 203-211
-
-
Pasquier, E.1
Kieran, M.W.2
Sterba, J.3
Shaked, Y.4
Baruchel, S.5
Oberlin, O.6
Kivivuori, M.S.7
Peyrl, A.8
Diawarra, M.9
Casanova, M.10
-
22
-
-
77950815444
-
Potent preclinical impact of metronomic low-dose oral topotecan combined with the antiangiogenic drug pazopanib for the treatment of ovarian cancer
-
Hashimoto K, Man S, Xu P, Cruz-Munoz W, Tang T, Kumar R, and Kerbel RS (2010). Potent preclinical impact of metronomic low-dose oral topotecan combined with the antiangiogenic drug pazopanib for the treatment of ovarian cancer. Mol Cancer Ther 9, 996-1006.
-
(2010)
Mol Cancer Ther
, vol.9
, pp. 996-1006
-
-
Hashimoto, K.1
Man, S.2
Xu, P.3
Cruz-Munoz, W.4
Tang, T.5
Kumar, R.6
Kerbel, R.S.7
-
23
-
-
77950811722
-
Bridging the gap between cyto-toxic and biologic therapy with metronomic topotecan and pazopanib in ovarian cancer
-
Merritt WM, Nick AM, Carroll AR, Lu C, Matsuo K, Dumble M, Jennings N, Zhang S, Lin YG, Spannuth WA, et al. (2010). Bridging the gap between cyto-toxic and biologic therapy with metronomic topotecan and pazopanib in ovarian cancer. Mol Cancer Ther 9, 985-995.
-
(2010)
Mol Cancer Ther
, vol.9
, pp. 985-995
-
-
Merritt, W.M.1
Nick, A.M.2
Carroll, A.R.3
Lu, C.4
Matsuo, K.5
Dumble, M.6
Jennings, N.7
Zhang, S.8
Lin, Y.G.9
Spannuth, W.A.10
-
24
-
-
80052495441
-
Metronomic oral topotecan with pazopanib is an active antiangiogenic regimen in mouse models of aggressive pediatric solid tumor
-
Kumar S, Mokhtari RB, Sheikh R, Wu B, Zhang L, Xu P, Man S, Oliveira ID, Yeger H, Kerbel RS, et al. (2011). Metronomic oral topotecan with pazopanib is an active antiangiogenic regimen in mouse models of aggressive pediatric solid tumor. Clin Cancer Res 17, 5656-5667.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 5656-5667
-
-
Kumar, S.1
Mokhtari, R.B.2
Sheikh, R.3
Wu, B.4
Zhang, L.5
Xu, P.6
Man, S.7
Oliveira, I.D.8
Yeger, H.9
Kerbel, R.S.10
-
25
-
-
84881052382
-
Phase I trial of metronomic oral topotecan in combination with pazo-panib utilizing a daily dosing schedule to treat recurrent or persistent gynecologic tumors
-
Chicago, IL. Abstract #5014
-
Tillmanns TD, Reed ME, Privett MC, Johns AL, Walker MS, and Houts AC (2012). Phase I trial of metronomic oral topotecan in combination with pazo-panib utilizing a daily dosing schedule to treat recurrent or persistent gynecologic tumors. In Proceedings of American Society for Clinical Oncology Annual Meeting (ASCO), Chicago, IL. Abstract #5014.
-
(2012)
In Proceedings of American Society For Clinical Oncology Annual Meeting (ASCO)
-
-
Tillmanns, T.D.1
Reed, M.E.2
Privett, M.C.3
Johns, A.L.4
Walker, M.S.5
Houts, A.C.6
-
26
-
-
34547486126
-
Phase II study of metronomic chemotherapy for recurrent malignant gliomas in adults
-
Kesari S, Schiff D, Doherty L, Gigas DC, Batchelor TT, Muzikansky A, O'Neill A, Drappatz J, Chen-Plotkin AS, Ramakrishna N, et al. (2007). Phase II study of metronomic chemotherapy for recurrent malignant gliomas in adults. Neuro Oncol 9, 354-363.
-
(2007)
Neuro Oncol
, vol.9
, pp. 354-363
-
-
Kesari, S.1
Schiff, D.2
Doherty, L.3
Gigas, D.C.4
Batchelor, T.T.5
Muzikansky, A.6
O'Neill, A.7
Drappatz, J.8
Chen-Plotkin, A.S.9
Ramakrishna, N.10
-
27
-
-
74049090120
-
Concerns about anti-angiogenic treatment in patients with glioblastoma multiforme
-
Verhoeff JJ, van Tellingen O, Claes A, Stalpers LJ, van Linde ME, Richel DJ, Leenders WP, and van Furth WR (2009). Concerns about anti-angiogenic treatment in patients with glioblastoma multiforme. BMC Cancer 9, 444.
-
(2009)
BMC Cancer
, vol.9
, pp. 444
-
-
Verhoeff, J.J.1
van Tellingen, O.2
Claes, A.3
Stalpers, L.J.4
van Linde, M.E.5
Richel, D.J.6
Leenders, W.P.7
van Furth, W.R.8
-
28
-
-
71649094684
-
Metronomic chemotherapy with daily, oral etoposide plus bevacizumab for recurrent malignant glioma: A phase II study
-
Reardon DA, Desjardins A, Vredenburgh JJ, Gururangan S, Sampson JH, Sathornsumetee S, McLendon RE, Herndon JE II, Marcello JE, Norfleet J, et al. (2009). Metronomic chemotherapy with daily, oral etoposide plus bevacizumab for recurrent malignant glioma: a phase II study. Br J Cancer 101, 1986-1994.
-
(2009)
Br J Cancer
, vol.101
, pp. 1986-1994
-
-
Reardon, D.A.1
Desjardins, A.2
Vredenburgh, J.J.3
Gururangan, S.4
Sampson, J.H.5
Sathornsumetee, S.6
McLendon, R.E.7
Herndon, J.E.I.I.8
Marcello, J.E.9
Norfleet, J.10
-
29
-
-
79959812904
-
Phase II study of metronomic chemotherapy with bevacizumab for recurrent glioblastoma after progression on bevacizumab therapy
-
Reardon DA, Desjardins A, Peters K, Gururangan S, Sampson J, Rich JN, McLendon R, Herndon JE II, Marcello J, Threatt S, et al. (2011). Phase II study of metronomic chemotherapy with bevacizumab for recurrent glioblastoma after progression on bevacizumab therapy. J Neurooncol 103, 371-379.
-
(2011)
J Neurooncol
, vol.103
, pp. 371-379
-
-
Reardon, D.A.1
Desjardins, A.2
Peters, K.3
Gururangan, S.4
Sampson, J.5
Rich, J.N.6
McLendon, R.7
Herndon, J.E.I.I.8
Marcello, J.9
Threatt, S.10
-
30
-
-
84856297005
-
Resistance to angiogenesis inhibitors in renal cell carcinoma
-
Tamaskar I, Dhillon J, and Pili R (2011). Resistance to angiogenesis inhibitors in renal cell carcinoma. Clin Adv Hematol Oncol 9, 101-110.
-
(2011)
Clin Adv Hematol Oncol
, vol.9
, pp. 101-110
-
-
Tamaskar, I.1
Dhillon, J.2
Pili, R.3
-
31
-
-
84881044295
-
Validating the use of CAIX and GLUT1 as endogenous markers for hypoxia in solid tumors
-
Anaheim, CA. Abstract #1130
-
Sorensen BS, Hao J, Overgaard J, Alsner J, and Horsman MR (2005). Validating the use of CAIX and GLUT1 as endogenous markers for hypoxia in solid tumors. In Proceedings of 96th Annual Meeting of the American Association for Cancer Research (AACR), Anaheim, CA. Abstract #1130.
-
(2005)
In Proceedings of 96th Annual Meeting of the American Association For Cancer Research (AACR)
-
-
Sorensen, B.S.1
Hao, J.2
Overgaard, J.3
Alsner, J.4
Horsman, M.R.5
-
32
-
-
79851509477
-
Role of hypoxia and glycolysis in the development of multi-drug resistance in human tumor cells and the establishment of an orthotopic multi-drug resistant tumor model in nude mice using hypoxic pre-conditioning
-
Milane L, Duan Z, and Amiji M (2011). Role of hypoxia and glycolysis in the development of multi-drug resistance in human tumor cells and the establishment of an orthotopic multi-drug resistant tumor model in nude mice using hypoxic pre-conditioning. Cancer Cell Int 11, 3.
-
(2011)
Cancer Cell Int
, vol.11
, pp. 3
-
-
Milane, L.1
Duan, Z.2
Amiji, M.3
-
33
-
-
47949099628
-
Modes of resistance to anti-angiogenic therapy
-
Bergers G and Hanahan D (2008). Modes of resistance to anti-angiogenic therapy. Nat Rev Cancer 8, 592-603.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 592-603
-
-
Bergers, G.1
Hanahan, D.2
-
34
-
-
77952673621
-
Mechanisms of resistance to anti-angiogenic therapy and development of third-generation anti-angiogenic drug candidates
-
Loges S, Schmidt T, and Carmeliet P (2010). Mechanisms of resistance to anti-angiogenic therapy and development of third-generation anti-angiogenic drug candidates. Genes Cancer 1, 12-25.
-
(2010)
Genes Cancer
, vol.1
, pp. 12-25
-
-
Loges, S.1
Schmidt, T.2
Carmeliet, P.3
-
35
-
-
0037154738
-
Effect of p53 status on tumor response to antiangiogenic therapy
-
Yu JL, Rak JW, Coomber BL, Hicklin DJ, and Kerbel RS (2002). Effect of p53 status on tumor response to antiangiogenic therapy. Science 295, 1526-1528.
-
(2002)
Science
, vol.295
, pp. 1526-1528
-
-
Yu, J.L.1
Rak, J.W.2
Coomber, B.L.3
Hicklin, D.J.4
Kerbel, R.S.5
-
36
-
-
77950916340
-
In vivo chemoresistance of prostate cancer in metronomic cyclophosphamide therapy
-
Thoenes L, Hoehn M, Kashirin R, Ogris M, Arnold GJ, Wagner E, and Guenther M (2010). In vivo chemoresistance of prostate cancer in metronomic cyclophosphamide therapy. J Proteomics 73, 1342-1354.
-
(2010)
J Proteomics
, vol.73
, pp. 1342-1354
-
-
Thoenes, L.1
Hoehn, M.2
Kashirin, R.3
Ogris, M.4
Arnold, G.J.5
Wagner, E.6
Guenther, M.7
-
37
-
-
84874753845
-
A comprehensive gene expression analysis of resistance formation upon metronomic cyclophosphamide therapy
-
Kubisch R, Meissner L, Krebs S, Blum H, Günther M, Roidl A, and Wagner E (2013). A comprehensive gene expression analysis of resistance formation upon metronomic cyclophosphamide therapy. Transl Oncol 6, 1-9.
-
(2013)
Transl Oncol
, vol.6
, pp. 1-9
-
-
Kubisch, R.1
Meissner, L.2
Krebs, S.3
Blum, H.4
Günther, M.5
Roidl, A.6
Wagner, E.7
-
38
-
-
84877872854
-
Concentration- and schedule-dependent effects of chemotherapy on the angiogenic potential and drug sensitivity of vascular endothelial cells
-
Pasquier E, Tuset MP, Street J, Sinnappan S, Mackenzie KL, Braguer D, Andre N, and Kavallaris M (2013). Concentration- and schedule-dependent effects of chemotherapy on the angiogenic potential and drug sensitivity of vascular endothelial cells. Angiogenesis 16, 373-386.
-
(2013)
Angiogenesis
, vol.16
, pp. 373-386
-
-
Pasquier, E.1
Tuset, M.P.2
Street, J.3
Sinnappan, S.4
Mackenzie, K.L.5
Braguer, D.6
Andre, N.7
Kavallaris, M.8
-
39
-
-
84862980672
-
Residual dormant cancer stem-cell foci are responsible for tumor relapse after antiangiogenic metronomic therapy in hepatocellular carcinoma xenografts
-
Martin-Padura I, Marighetti P, Agliano A, Colombo F, Larzabal L, Redrado M, Bleau AM, Prior C, Bertolini F, and Calvo A (2012). Residual dormant cancer stem-cell foci are responsible for tumor relapse after antiangiogenic metronomic therapy in hepatocellular carcinoma xenografts. Lab Invest 92, 952-966.
-
(2012)
Lab Invest
, vol.92
, pp. 952-966
-
-
Martin-Padura, I.1
Marighetti, P.2
Agliano, A.3
Colombo, F.4
Larzabal, L.5
Redrado, M.6
Bleau, A.M.7
Prior, C.8
Bertolini, F.9
Calvo, A.10
-
40
-
-
78650991789
-
Tumors that acquire resistance to low-dose metronomic cyclo-phosphamide retain sensitivity to maximum tolerated dose cyclophosphamide
-
Emmenegger U, Francia G, Chow A, Shaked Y, Kouri A, Man S, and Kerbel RS (2011). Tumors that acquire resistance to low-dose metronomic cyclo-phosphamide retain sensitivity to maximum tolerated dose cyclophosphamide. Neoplasia 13, 40-48.
-
(2011)
Neoplasia
, vol.13
, pp. 40-48
-
-
Emmenegger, U.1
Francia, G.2
Chow, A.3
Shaked, Y.4
Kouri, A.5
Man, S.6
Kerbel, R.S.7
-
41
-
-
77950935041
-
Human neuroblastoma cells with MYCN amplification are selectively resistant to oxidative stress by transcriptionally up-regulating glutamate cysteine ligase
-
Veas-Perez Tudela M, Delgado-Esteban M, Cuende J, Bolanos JP, and Almeida A (2010). Human neuroblastoma cells with MYCN amplification are selectively resistant to oxidative stress by transcriptionally up-regulating glutamate cysteine ligase. J Neurochem 113, 819-825.
-
(2010)
J Neurochem
, vol.113
, pp. 819-825
-
-
Veas-Perez, T.M.1
Delgado-Esteban, M.2
Cuende, J.3
Bolanos, J.P.4
Almeida, A.5
-
42
-
-
84863422466
-
Overcoming disappointing results with anti-angiogenic therapy by targeting hypoxia
-
Rapisarda A and Melillo G (2012). Overcoming disappointing results with anti-angiogenic therapy by targeting hypoxia. Nat Rev Clin Oncol 9, 378-390.
-
(2012)
Nat Rev Clin Oncol
, vol.9
, pp. 378-390
-
-
Rapisarda, A.1
Melillo, G.2
-
43
-
-
51049095933
-
Topotecan inhibits vascular endothelial growth factor production and angiogenic activity induced by hypoxia in human neuro-blastoma by targeting hypoxia-inducible factor-1α and -2α
-
Puppo M, Battaglia F, Ottaviano C, Delfino S, Ribatti D, Varesio L, and Bosco MC (2008). Topotecan inhibits vascular endothelial growth factor production and angiogenic activity induced by hypoxia in human neuro-blastoma by targeting hypoxia-inducible factor-1α and -2α. Mol Cancer Ther 7, 1974-1984.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 1974-1984
-
-
Puppo, M.1
Battaglia, F.2
Ottaviano, C.3
Delfino, S.4
Ribatti, D.5
Varesio, L.6
Bosco, M.C.7
-
44
-
-
19644376976
-
Topotecan blocks hypoxia-inducible factor-1α and vascular endothelial growth factor expression induced by insulin-like growth factor-I in neuroblastoma cells
-
Beppu K, Nakamura K, Linehan WM, Rapisarda A, and Thiele CJ (2005). Topotecan blocks hypoxia-inducible factor-1α and vascular endothelial growth factor expression induced by insulin-like growth factor-I in neuroblastoma cells. Cancer Res 65, 4775-4781.
-
(2005)
Cancer Res
, vol.65
, pp. 4775-4781
-
-
Beppu, K.1
Nakamura, K.2
Linehan, W.M.3
Rapisarda, A.4
Thiele, C.J.5
-
45
-
-
65249183165
-
PDGF-C induces maturation of blood vessels in a model of glioblastoma and attenuates the response to anti-VEGF treatment
-
di Tomaso E, London N, Fuja D, Logie J, Tyrrell JA, Kamoun W, Munn LL, and Jain RK (2009). PDGF-C induces maturation of blood vessels in a model of glioblastoma and attenuates the response to anti-VEGF treatment. PLoS One 4, e5123.
-
(2009)
PLoS One
, vol.4
-
-
Di, T.E.1
London, N.2
Fuja, D.3
Logie, J.4
Tyrrell, J.A.5
Kamoun, W.6
Munn, L.L.7
Jain, R.K.8
-
46
-
-
0345798150
-
Endothelial and non-endothelial sources of PDGF-B regulate pericyte recruitment and influence vascular pattern formation in tumors
-
Abramsson A, Lindblom P, and Betsholtz C (2003). Endothelial and non-endothelial sources of PDGF-B regulate pericyte recruitment and influence vascular pattern formation in tumors. J Clin Invest 112, 1142-1151.
-
(2003)
J Clin Invest
, vol.112
, pp. 1142-1151
-
-
Abramsson, A.1
Lindblom, P.2
Betsholtz, C.3
-
47
-
-
79957571352
-
Costunolide causes mitotic arrest and enhances radiosensitivity in human hepatocellular carcinoma cells
-
Liu CY, Chang HS, Chen IS, Chen CJ, Hsu ML, Fu SL, and Chen YJ (2011). Costunolide causes mitotic arrest and enhances radiosensitivity in human hepatocellular carcinoma cells. Radiat Oncol 6, 56.
-
(2011)
Radiat Oncol
, vol.6
, pp. 56
-
-
Liu, C.Y.1
Chang, H.S.2
Chen, I.S.3
Chen, C.J.4
Hsu, M.L.5
Fu, S.L.6
Chen, Y.J.7
-
48
-
-
79551688962
-
Squamocin modulates histone H3 phosphorylation levels and induces G1 phase arrest and apoptosis in cancer cells
-
Lee CC, Lin YH, Chang WH, Lin PC, Wu YC, and Chang JG (2011). Squamocin modulates histone H3 phosphorylation levels and induces G1 phase arrest and apoptosis in cancer cells. BMC Cancer 11, 58.
-
(2011)
BMC Cancer
, vol.11
, pp. 58
-
-
Lee, C.C.1
Lin, Y.H.2
Chang, W.H.3
Lin, P.C.4
Wu, Y.C.5
Chang, J.G.6
-
49
-
-
10344240885
-
Cell cycle kinase inhibitor expression and hypoxia-induced cell cycle arrest in human cancer cell lines
-
Box AH and Demetrick DJ (2004). Cell cycle kinase inhibitor expression and hypoxia-induced cell cycle arrest in human cancer cell lines. Carcinogenesis 25, 2325-2335.
-
(2004)
Carcinogenesis
, vol.25
, pp. 2325-2335
-
-
Box, A.H.1
Demetrick, D.J.2
-
50
-
-
84857040751
-
Cyclin-dependent kinase inhibitor, P276-00, inhibits HIF-1α and induces G2/M arrest under hypoxia in prostate cancer cells
-
Manohar SM, Padgaonkar AA, Jalota-Badhwar A, Rao SV, and Joshi KS (2012). Cyclin-dependent kinase inhibitor, P276-00, inhibits HIF-1α and induces G2/M arrest under hypoxia in prostate cancer cells. Prostate Cancer Prostatic Dis 15, 15-27.
-
(2012)
Prostate Cancer Prostatic Dis
, vol.15
, pp. 15-27
-
-
Manohar, S.M.1
Padgaonkar, A.A.2
Jalota-Badhwar, A.3
Rao, S.V.4
Joshi, K.S.5
-
51
-
-
77953982390
-
XQ2, a novel TPZ derivative, induced G2/M phase arrest and apoptosis under hypoxia in non-small cell lung cancer cells
-
Lou J, Zhou X, Weng Q, Wang DD, Xia Q, Hu Y, He Q, Yang B, and Luo P (2010). XQ2, a novel TPZ derivative, induced G2/M phase arrest and apoptosis under hypoxia in non-small cell lung cancer cells. Biosci Biotechnol Biochem 74, 1181-1187.
-
(2010)
Biosci Biotechnol Biochem
, vol.74
, pp. 1181-1187
-
-
Lou, J.1
Zhou, X.2
Weng, Q.3
Wang, D.D.4
Xia, Q.5
Hu, Y.6
He, Q.7
Yang, B.8
Luo, P.9
-
52
-
-
0038823705
-
Tracking the cell cycle origins for escape from topotecan action by breast cancer cells
-
Feeney GP, Errington RJ, Wiltshire M, Marquez N, Chappell SC, and Smith PJ (2003). Tracking the cell cycle origins for escape from topotecan action by breast cancer cells. Br J Cancer 88, 1310-1317.
-
(2003)
Br J Cancer
, vol.88
, pp. 1310-1317
-
-
Feeney, G.P.1
Errington, R.J.2
Wiltshire, M.3
Marquez, N.4
Chappell, S.C.5
Smith, P.J.6
-
53
-
-
0034900493
-
Glucose transporter Glut-1 expression correlates with tumor hypoxia and predicts metastasis-free survival in advanced carcinoma of the cervix
-
Airley R, Loncaster J, Davidson S, Bromley M, Roberts S, Patterson A, Hunter R, Stratford I, and West C (2001). Glucose transporter Glut-1 expression correlates with tumor hypoxia and predicts metastasis-free survival in advanced carcinoma of the cervix. Clin Cancer Res 7, 928-934.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 928-934
-
-
Airley, R.1
Loncaster, J.2
Davidson, S.3
Bromley, M.4
Roberts, S.5
Patterson, A.6
Hunter, R.7
Stratford, I.8
West, C.9
-
54
-
-
66249108601
-
Understanding the Warburg effect: The metabolic requirements of cell proliferation
-
Vander Heiden MG, Cantley LC, and Thompson CB (2009). Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 324, 1029-1033.
-
(2009)
Science
, vol.324
, pp. 1029-1033
-
-
Vander, H.M.G.1
Cantley, L.C.2
Thompson, C.B.3
-
55
-
-
78650403118
-
Combinatorial regulation of neuroblastoma tumor progression by N-Myc and hypoxia inducible factor HIF-1α
-
Qing G, Skuli N, Mayes PA, Pawel B, Martinez D, Maris JM, and Simon MC (2010). Combinatorial regulation of neuroblastoma tumor progression by N-Myc and hypoxia inducible factor HIF-1α. Cancer Res 70, 10351-10361.
-
(2010)
Cancer Res
, vol.70
, pp. 10351-10361
-
-
Qing, G.1
Skuli, N.2
Mayes, P.A.3
Pawel, B.4
Martinez, D.5
Maris, J.M.6
Simon, M.C.7
-
56
-
-
84864122028
-
Glycolysis inhibitors as a potential therapeutic option to treat aggressive neuroblastoma expressing GLUT1
-
Matsushita K, Uchida K, Saigusa S, Ide S, Hashimoto K, Koike Y, Otake K, Inoue M, Tanaka K, and Kusunoki M (2012). Glycolysis inhibitors as a potential therapeutic option to treat aggressive neuroblastoma expressing GLUT1. J Pediatr Surg 47, 1323-1330.
-
(2012)
J Pediatr Surg
, vol.47
, pp. 1323-1330
-
-
Matsushita, K.1
Uchida, K.2
Saigusa, S.3
Ide, S.4
Hashimoto, K.5
Koike, Y.6
Otake, K.7
Inoue, M.8
Tanaka, K.9
Kusunoki, M.10
-
57
-
-
0036808431
-
Clinical significance of glucose transporter 1 (GLUT1) expression in human breast carcinoma
-
Kang SS, Chun YK, Hur MH, Lee HK, Kim YJ, Hong SR, Lee JH, Lee SG, and Park YK (2002). Clinical significance of glucose transporter 1 (GLUT1) expression in human breast carcinoma. Jpn J Cancer Res 93, 1123-1128.
-
(2002)
Jpn J Cancer Res
, vol.93
, pp. 1123-1128
-
-
Kang, S.S.1
Chun, Y.K.2
Hur, M.H.3
Lee, H.K.4
Kim, Y.J.5
Hong, S.R.6
Lee, J.H.7
Lee, S.G.8
Park, Y.K.9
-
58
-
-
69349105825
-
GLUT1 gene is a potential hypoxic marker in colorectal cancer patients
-
Chung FY, Huang MY, Yeh CS, Chang HJ, Cheng TL, Yen LC, Wang JY, and Lin SR (2009). GLUT1 gene is a potential hypoxic marker in colorectal cancer patients. BMC Cancer 9, 241.
-
(2009)
BMC Cancer
, vol.9
, pp. 241
-
-
Chung, F.Y.1
Huang, M.Y.2
Yeh, C.S.3
Chang, H.J.4
Cheng, T.L.5
Yen, L.C.6
Wang, J.Y.7
Lin, S.R.8
-
59
-
-
79955837932
-
Metabolic markers in relation to hypoxia; staining patterns and colocalization of pimonidazole, HIF-1α, CAIX, LDH-5, GLUT-1, MCT1 and MCT4
-
Rademakers SE, Lok J, van der Kogel AJ, Bussink J, and Kaanders JH (2011). Metabolic markers in relation to hypoxia; staining patterns and colocalization of pimonidazole, HIF-1α, CAIX, LDH-5, GLUT-1, MCT1 and MCT4. BMC Cancer 11, 167.
-
(2011)
BMC Cancer
, vol.11
, pp. 167
-
-
Rademakers, S.E.1
Lok, J.2
Van der, K.A.J.3
Bussink, J.4
Kaanders, J.H.5
-
60
-
-
33746924468
-
Hexokinase II: Cancer's double-edged sword acting as both facilitator and gatekeeper of malignancy when bound to mitochondria
-
Mathupala SP, Ko YH, and Pedersen PL (2006). Hexokinase II: cancer's double-edged sword acting as both facilitator and gatekeeper of malignancy when bound to mitochondria. Oncogene 25, 4777-4786.
-
(2006)
Oncogene
, vol.25
, pp. 4777-4786
-
-
Mathupala, S.P.1
Ko, Y.H.2
Pedersen, P.L.3
-
61
-
-
84872679485
-
Hexokinase-2-mediated aerobic glycolysis is integral to cerebellar neurogenesis and pathogenesis of medulloblastoma
-
Gershon RT, Crowther AJ, Tikunov A, Garcia I, Annis R, Yuan H, Miller CR, Macdonald J, Olson J, and Deshmukh M (2013). Hexokinase-2-mediated aerobic glycolysis is integral to cerebellar neurogenesis and pathogenesis of medulloblastoma. Cancer Metab 1, 2.
-
(2013)
Cancer Metab
, vol.1
, pp. 2
-
-
Gershon, R.T.1
Crowther, A.J.2
Tikunov, A.3
Garcia, I.4
Annis, R.5
Yuan, H.6
Miller, C.R.7
Macdonald, J.8
Olson, J.9
Deshmukh, M.10
-
62
-
-
70350220872
-
Hexokinase II detachment from the mitochondria potentiates cisplatin induced cytotoxicity through a caspase-2 dependent mechanism
-
Shulga N, Wilson-Smith R, and Pastorino JG (2009). Hexokinase II detachment from the mitochondria potentiates cisplatin induced cytotoxicity through a caspase-2 dependent mechanism. Cell Cycle 8, 3355-3364.
-
(2009)
Cell Cycle
, vol.8
, pp. 3355-3364
-
-
Shulga, N.1
Wilson-Smith, R.2
Pastorino, J.G.3
-
63
-
-
67650380136
-
Biomarkers of response and resistance to anti-angiogenic therapy
-
Jain RK, Duda DG, Willett CG, Sahani DV, Zhu AX, Loeffler JS, Batchelor TT, and Sorensen AG (2009). Biomarkers of response and resistance to anti-angiogenic therapy. Nat Rev Clin Oncol 6, 327-338.
-
(2009)
Nat Rev Clin Oncol
, vol.6
, pp. 327-338
-
-
Jain, R.K.1
Duda, D.G.2
Willett, C.G.3
Sahani, D.V.4
Zhu, A.X.5
Loeffler, J.S.6
Batchelor, T.T.7
Sorensen, A.G.8
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