Metronomic chemotherapy with daily, oral etoposide plus bevacizumab for recurrent malignant glioma: A phase II study

British Journal of Cancer

Volumn 101, Issue 12, 2009, Pages 1986-1994

  Reardon, D A ^a   Desjardins, A ^a   Vredenburgh, J J ^a   Gururangan, S ^a   Sampson, J H ^a   Sathornsumetee, S ^a   McLendon, R E ^a   Herndon, J E ^a   Marcello, J E ^a   Norfleet, J ^a   Friedman, A H ^a   Bigner, D D ^a   Friedman, H S ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Angiogenesis; Bevacizumab; Glioblastoma; Malignant glioma; Metronomic chemotherapy; Vascular endothelial growth factor

Indexed keywords

BEVACIZUMAB; CARBONATE DEHYDRATASE IX; ETOPOSIDE; FLUORODEOXYGLUCOSE F 18; HYPOXIA INDUCIBLE FACTOR 2ALPHA; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 2;

ADJUVANT THERAPY; ADULT; ANEMIA; ANOREXIA; ARTICLE; BRAIN HEMORRHAGE; CANCER RADIOTHERAPY; CANCER SURGERY; CHEMOTHERAPY INDUCED EMESIS; CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; DRUG DOSE REDUCTION; DRUG ERUPTION; DRUG FATALITY; DRUG SAFETY; DRUG TREATMENT FAILURE; FATIGUE; FEMALE; GLIOBLASTOMA; HUMAN; HYPERTENSION; IMMUNOHISTOCHEMISTRY; INFECTION; MAJOR CLINICAL STUDY; MALE; MUCOSA INFLAMMATION; MULTIPLE CYCLE TREATMENT; NAUSEA; NEUTROPENIA; OPEN STUDY; OVERALL SURVIVAL; PATIENT COMPLIANCE; PERIPHERAL NEUROPATHY; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; PROGNOSIS; PROGRESSION FREE SURVIVAL; PROTEINURIA; RECURRENT CANCER; SIDE EFFECT; THROMBOSIS;

ADMINISTRATION, ORAL; ADULT; AGED; ANTIBODIES, MONOCLONAL; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BRAIN NEOPLASMS; ETOPOSIDE; FEMALE; GLIOMA; HUMANS; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; TREATMENT FAILURE; TUMOR MARKERS, BIOLOGICAL; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 71649094684     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/sj.bjc.6605412     Document Type: Article

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