메뉴 건너뛰기




Volumn 28, Issue 2, 2012, Pages 439-445

Enhanced anti-tumor and anti-angiogenic effects of metronomic cyclophosphamide combined with Endostar in a xenograft model of human lung cancer

Author keywords

Angiogenesis; Cyclophosphamide; Endostar; Metronomic chemotherapy; Non small cell lung cancer

Indexed keywords

CYCLOPHOSPHAMIDE; RECOMBINANT ENDOSTATIN;

EID: 84863445509     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2012.1828     Document Type: Article
Times cited : (13)

References (30)
  • 3
    • 77649104920 scopus 로고    scopus 로고
    • First-line systemic chemotherapy in the treatment of advanced non-small cell lung cancer: A systematic review
    • Goffin J, Lacchetti C, Ellis PM, Ung YC and Evans WK: First-line systemic chemotherapy in the treatment of advanced non-small cell lung cancer: a systematic review. J Thorac Oncol 5: 260-274, 2010.
    • (2010) J Thorac Oncol , vol.5 , pp. 260-274
    • Goffin, J.1    Lacchetti, C.2    Ellis, P.M.3    Ung, Y.C.4    Evans, W.K.5
  • 4
    • 78649364656 scopus 로고    scopus 로고
    • How to integrate current knowledge in selecting patients for first line in NSCLC?
    • Felip E, Cedrés S, Checa E and Martinez P: How to integrate current knowledge in selecting patients for first line in NSCLC? Ann Oncol 21 (Suppl 7): 230-233, 2010.
    • (2010) Ann Oncol , vol.21 , Issue.SUPPL. 7 , pp. 230-233
    • Felip, E.1    Cedrés, S.2    Checa, E.3    Martinez, P.4
  • 5
    • 77958550661 scopus 로고    scopus 로고
    • Maintenance and consolidation therapy in patients with unresectable stage III/IV non-small cell lung cancer
    • Thatcher N and Heighway J: Maintenance and consolidation therapy in patients with unresectable stage III/IV non-small cell lung cancer. Oncologist 15: 1034-1042, 2010.
    • (2010) Oncologist , vol.15 , pp. 1034-1042
    • Thatcher, N.1    Heighway, J.2
  • 6
    • 2942615257 scopus 로고    scopus 로고
    • The anti-angiogenic basis of metronomic chemotherapy
    • Kerbel RS and Kamen BA: The anti-angiogenic basis of metronomic chemotherapy. Nat Rev Cancer 4: 423-436, 2004. (Pubitemid 38745528)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.6 , pp. 423-436
    • Kerbel, R.S.1    Kamen, B.A.2
  • 7
    • 77955172181 scopus 로고    scopus 로고
    • Metronomic chemotherapy: New rationale for new directions
    • Pasquier E, Kavallaris M and Andre N: Metronomic chemotherapy: new rationale for new directions. Nat Rev Clin Oncol 7: 455-465, 2010.
    • (2010) Nat Rev Clin Oncol , vol.7 , pp. 455-465
    • Pasquier, E.1    Kavallaris, M.2    Andre, N.3
  • 9
    • 34548441251 scopus 로고    scopus 로고
    • A pilot study of metronomic temozolomide treatment in patients with recurrent temozolomiderefractory glioblastoma
    • Kong DS, Lee JI, Kim WS, Son MJ, Lim do H, Kim ST, Park K, Kim JH, Eoh W and Nam DH: A pilot study of metronomic temozolomide treatment in patients with recurrent temozolomiderefractory glioblastoma. Oncol Rep 16: 1117-1121, 2006.
    • (2006) Oncol Rep , vol.16 , pp. 1117-1121
    • Kong, D.S.1    Lee, J.I.2    Kim, W.S.3    Son, M.J.4    Lim Do, H.5    Kim, S.T.6    Park, K.7    Kim, J.H.8    Eoh, W.9    Nam, D.H.10
  • 11
    • 32344443105 scopus 로고    scopus 로고
    • China offers alternative gateway for experimental drugs
    • DOI 10.1038/nbt0206-117, PII NBT0206117
    • Jia H and Kling J: China offers alternative gateway for experimental drugs. Nat Biotechnol 24: 117-118, 2006. (Pubitemid 43221686)
    • (2006) Nature Biotechnology , vol.24 , Issue.2 , pp. 117-118
    • Jia, H.1    Kling, J.2
  • 12
    • 14644446018 scopus 로고    scopus 로고
    • A multitargeted, metronomic, and maximum-tolerated dose 'chemo-switch' regimen is antiangiogenic, producing objective responses and survival benefit in a mouse model of cancer
    • DOI 10.1200/JCO.2005.07.093
    • Pietras K and Hanahan D: A multitargeted, metronomic, and maximum-tolerated dose 'chemo-switch' regimen is antiangiogenic, producing objective responses and survival benefit in a mouse model of cancer. J Clin Oncol 23: 939-952, 2005. (Pubitemid 46202314)
    • (2005) Journal of Clinical Oncology , vol.23 , Issue.5 , pp. 939-952
    • Pietras, K.1    Hanahan, D.2
  • 13
    • 0041589524 scopus 로고    scopus 로고
    • Maximum tolerable dose and low-dose metronomic chemotherapy have opposite effects on the mobilization and viability of circulating endothelial progenitor cells
    • Bertolini F, Paul S, Mancuso P, Monestiroli S, Gobbi A, Shaked Y and Kerbel RS: Maximum tolerable dose and low-dose metronomic chemotherapy have opposite effects on the mobilization and viability of circulating endothelial progenitor cells. Cancer Res 63: 4342-4346, 2003. (Pubitemid 36951001)
    • (2003) Cancer Research , vol.63 , Issue.15 , pp. 4342-4346
    • Bertolini, F.1    Paul, S.2    Mancuso, P.3    Monestiroli, S.4    Gobbi, A.5    Shaked, Y.6    Kerbel, R.S.7
  • 14
    • 67650474132 scopus 로고    scopus 로고
    • Circulating endothelial cells and circulating progenitor cells in breast cancer: Relationship to endothelial damage/dysfunction/apoptosis, clinicopathologic factors, and the Nottingham Prognostic Index
    • Goon PK, Lip GY, Stonelake PS and Blann AD: Circulating endothelial cells and circulating progenitor cells in breast cancer: relationship to endothelial damage/dysfunction/apoptosis, clinicopathologic factors, and the Nottingham Prognostic Index. Neoplasia 11: 771-779, 2009.
    • (2009) Neoplasia , vol.11 , pp. 771-779
    • Goon, P.K.1    Lip, G.Y.2    Stonelake, P.S.3    Blann, A.D.4
  • 15
    • 33646395092 scopus 로고    scopus 로고
    • Circulating endothelial cells, endothelial progenitor cells, and endothelial microparticles in cancer
    • Goon PK, Lip GY, Boos CJ, Stonelake PS and Blann AD: Circulating endothelial cells, endothelial progenitor cells, and endothelial microparticles in cancer. Neoplasia 8: 79-88, 2006.
    • (2006) Neoplasia , vol.8 , pp. 79-88
    • Goon, P.K.1    Lip, G.Y.2    Boos, C.J.3    Stonelake, P.S.4    Blann, A.D.5
  • 17
    • 33947732977 scopus 로고    scopus 로고
    • Angiogenesis: An organizing principle for drug discovery?
    • Folkman J: Angiogenesis: an organizing principle for drug discovery? Nat Rev Drug Discov 6: 273-286, 2007.
    • (2007) Nat Rev Drug Discov , vol.6 , pp. 273-286
    • Folkman, J.1
  • 18
    • 77955496673 scopus 로고    scopus 로고
    • Pericytes and vessel maturation during tumor angiogenesis and metastasis
    • Raza A, Franklin MJ and Dudek AZ: Pericytes and vessel maturation during tumor angiogenesis and metastasis. Am J Hematol 85: 593-598, 2010.
    • (2010) Am J Hematol , vol.85 , pp. 593-598
    • Raza, A.1    Franklin, M.J.2    Dudek, A.Z.3
  • 19
    • 32944469620 scopus 로고    scopus 로고
    • Lymphangiogenesis and angiogenesis in bladder cancer: Prognostic implications and regulation by vascular endothelial growth factors-A, -C, and -D
    • DOI 10.1158/1078-0432.CCR-05-1284
    • Miyata Y, Kanda S, Ohba K, Nomata K, Hayashida Y, Eguchi J, Hayashi T and Kanetake H: Lymphangiogenesis and angiogenesis in bladder cancer: prognostic implications and regulation by vascular endothelial growth factors-A, -C, and -D. Clin Cancer Res 12: 800-806, 2006. (Pubitemid 43259860)
    • (2006) Clinical Cancer Research , vol.12 , Issue.3 I , pp. 800-806
    • Miyata, Y.1    Kanda, S.2    Ohba, K.3    Nomata, K.4    Hayashida, Y.5    Eguchi, J.6    Hayashi, T.7    Kanetake, H.8
  • 20
    • 77249173423 scopus 로고    scopus 로고
    • Flow cytometric detection of circulating endothelial cells and endothelial progenitor cells in healthy subjects
    • Mariucci S, Rovati B, Bencardino K, Manzoni M and Danova M: Flow cytometric detection of circulating endothelial cells and endothelial progenitor cells in healthy subjects. Int J Lab Hematol 32: E40-E48, 2008.
    • (2008) Int J Lab Hematol , vol.32
    • Mariucci, S.1    Rovati, B.2    Bencardino, K.3    Manzoni, M.4    Danova, M.5
  • 21
    • 71249150957 scopus 로고    scopus 로고
    • Circulating endothelial cells as biomarkers for angiogenesis in tumor progression
    • Schol Ed
    • Martin-Padura I and Bertolini F: Circulating endothelial cells as biomarkers for angiogenesis in tumor progression. Front Biosci (Schol Ed) 1: 304-318, 2009.
    • (2009) Front Biosci , vol.1 , pp. 304-318
    • Martin-Padura, I.1    Bertolini, F.2
  • 22
    • 33750286135 scopus 로고    scopus 로고
    • The multifaceted circulating endothelial cell in cancer: Towards marker and target identification
    • DOI 10.1038/nrc1971, PII NRC1971
    • Bertolini F, Shaked Y, Mancuso P and Kerbel RS: The multifaceted circulating endothelial cell in cancer: towards marker and target identification. Nat Rev Cancer 6: 835-845, 2006. (Pubitemid 44629895)
    • (2006) Nature Reviews Cancer , vol.6 , Issue.11 , pp. 835-845
    • Bertolini, F.1    Shaked, Y.2    Mancuso, P.3    Kerbel, R.S.4
  • 24
    • 33344459620 scopus 로고    scopus 로고
    • Circulating endothelial cells and angiogenic serum factors during neoadjuvant chemotherapy of primary breast cancer
    • DOI 10.1038/sj.bjc.6602952
    • Furstenberger G, von Moos R, Lucas R, Thurlimann B, Senn HJ, Hamacher J and Boneberg EM: Circulating endothelial cells and angiogenic serum factors during neoadjuvant chemotherapy of primary breast cancer. Br J Cancer 94: 524-531, 2006. (Pubitemid 43289756)
    • (2006) British Journal of Cancer , vol.94 , Issue.4 , pp. 524-531
    • Furstenberger, G.1    Von Moos, R.2    Lucas, R.3    Thurlimann, B.4    Senn, H.-J.5    Hamacher, J.6    Boneberg, E.-M.7
  • 26
    • 34347204528 scopus 로고    scopus 로고
    • Metronomic chemotherapy: An antiangiogenic scheduling
    • Laquente B, Vinals F and Germa JR: Metronomic chemotherapy: an antiangiogenic scheduling. Clin Transl Oncol 9: 93-98, 2007.
    • (2007) Clin Transl Oncol , vol.9 , pp. 93-98
    • Laquente, B.1    Vinals, F.2    Germa, J.R.3
  • 27
    • 34547106834 scopus 로고    scopus 로고
    • Endostar, a novel recombinant human endostatin, exerts antiangiogenic effect via blocking VEGF-induced tyrosine phosphorylation of KDR/Flk-1 of endothelial cells
    • DOI 10.1016/j.bbrc.2007.06.155, PII S0006291X07014027
    • Ling Y, Yang Y, Lu N, You QD, Wang S, Gao Y, Chen Y and Guo QL: Endostar, a novel recombinant human endostatin, exerts antiangiogenic effect via blocking VEGF-induced tyrosine phosphorylation of KDR/Flk-1 of endothelial cells. Biochem Biophys Res Commun 361: 79-84, 2007. (Pubitemid 47102270)
    • (2007) Biochemical and Biophysical Research Communications , vol.361 , Issue.1 , pp. 79-84
    • Ling, Y.1    Yang, Y.2    Lu, N.3    You, Q.-d.4    Wang, S.5    Gao, Y.6    Chen, Y.7    Guo, Q.-L.8
  • 29
    • 77957326888 scopus 로고    scopus 로고
    • Sorafenib enhances the in vitro anti-endothelial effects of low dose (metronomic) chemotherapy
    • Murray A, Little SJ, Stanley P, Maraveyas A and Cawkwell L: Sorafenib enhances the in vitro anti-endothelial effects of low dose (metronomic) chemotherapy. Oncol Rep 24: 1049-1058, 2010.
    • (2010) Oncol Rep , vol.24 , pp. 1049-1058
    • Murray, A.1    Little, S.J.2    Stanley, P.3    Maraveyas, A.4    Cawkwell, L.5
  • 30
    • 78650491373 scopus 로고    scopus 로고
    • Strategies for prolonged therapy in patients with advanced non-small-cell lung cancer
    • Fidias P and Novello S: Strategies for prolonged therapy in patients with advanced non-small-cell lung cancer. J Clin Oncol 28: 5116-5123, 2010.
    • (2010) J Clin Oncol , vol.28 , pp. 5116-5123
    • Fidias, P.1    Novello, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.