메뉴 건너뛰기




Volumn 19, Issue 7, 2010, Pages 859-874

New anti-angiogenic strategies in pediatric solid malignancies: Agents and biomarkers of a near future

Author keywords

Angiogenesis; Antiangiogenesis; Biomarkers; Cancer; Children; Circulating endothelial cells; Circulating endothelial progenitor cells

Indexed keywords

ANGIOGENESIS INHIBITOR; ANGIOSTATIN; BASIC FIBROBLAST GROWTH FACTOR; BEVACIZUMAB; CISPLATIN; CYCLOPHOSPHAMIDE; ENDOSTATIN; FUMAGILLOL CHLOROACETYLCARBAMATE; GELATINASE A; GELATINASE B; IMATINIB; INTEGRIN; NERVE CELL ADHESION MOLECULE; PAZOPANIB; PLACENTAL GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR; SEMAXANIB; SEMAXINIB; SERINE 2 METHOXY 5 [2 (3,4,5 TRIMETHOXYPHENYL)VINYL]ANILIDE; SORAFENIB; SUNITINIB; TEMOZOLOMIDE; THALIDOMIDE; THROMBOSPONDIN 1; TISSUE INHIBITOR OF METALLOPROTEINASE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VALPROIC ACID; VANDETANIB; VASCULAR ENDOTHELIAL CADHERIN; VASCULOTROPIN; VASCULOTROPIN RECEPTOR;

EID: 77953396751     PISSN: 13543784     EISSN: None     Source Type: Journal    
DOI: 10.1517/13543784.2010.487654     Document Type: Review
Times cited : (7)

References (101)
  • 1
    • 72449151349 scopus 로고    scopus 로고
    • Childhood cancer mortality in Europe 1970-2007
    • Bosetti C, Bertuccio P, Chatenoud L, et al. Childhood cancer mortality in Europe, 1970-2007. Eur J Cancer 2010;46(2):384-394
    • (2010) Eur J Cancer , vol.46 , Issue.2 , pp. 384-394
    • Bosetti, C.1    Bertuccio, P.2    Chatenoud, L.3
  • 2
    • 33747125364 scopus 로고    scopus 로고
    • Trends in survival after childhood cancer in Europe, 1978-1997: Report from the Automated Childhood Cancer Information System project (ACCIS)
    • DOI 10.1016/j.ejca.2006.05.006, PII S0959804906004424, Cancer in Children and Adolescents in Europe
    • Magnani C, Pastore G, Coebergh JW, et al. Trends in survival after childhood cancer in Europe, 1978-1997: report from the Automated Childhood Cancer Information System project (ACCIS). Eur J Cancer 2006;42(13):1981-2005 (Pubitemid 44224052)
    • (2006) European Journal of Cancer , vol.42 , Issue.13 , pp. 1981-2005
    • Magnani, C.1    Pastore, G.2    Coebergh, J.W.3    Viscomi, S.4    Spix, C.5    Steliarova-Foucher, E.6
  • 3
    • 33748502962 scopus 로고    scopus 로고
    • Survival after relapse in children with solid tumors: A follow-up study from the Italian off-therapy registry
    • Ceschel S, Casotto V, Valsecchi MG, et al. Survival after relapse in children with solid tumors: a follow-up study from the Italian off-therapy registry. Pediatr Blood Cancer 2006;47(5):560-566
    • (2006) Pediatr Blood Cancer , vol.47 , Issue.5 , pp. 560-566
    • Ceschel, S.1    Casotto, V.2    Valsecchi, M.G.3
  • 4
    • 33750207051 scopus 로고    scopus 로고
    • Secondary dissemination in children with high-grade malignant gliomas and diffuse intrinsic pontine gliomas
    • Wagner S, Benesch M, Berthold F, et al. Secondary dissemination in children with high-grade malignant gliomas and diffuse intrinsic pontine gliomas. Br J Cancer 2006;95(8):991-997
    • (2006) Br J Cancer , vol.95 , Issue.8 , pp. 991-997
    • Wagner, S.1    Benesch, M.2    Berthold, F.3
  • 5
    • 43249095919 scopus 로고    scopus 로고
    • Tumor angiogenesis
    • Kerbel RS. Tumor angiogenesis. N Engl J Med 2008;358(19):2039-2049
    • (2008) N Engl J Med , vol.358 , Issue.19 , pp. 2039-2049
    • Kerbel, R.S.1
  • 6
    • 33644833910 scopus 로고    scopus 로고
    • Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma
    • Motzer RJ, Michaelson MD, Redman BG, et al. Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma. J Clin Oncol 2006;24(1):16-24
    • (2006) J Clin Oncol , vol.24 , Issue.1 , pp. 16-24
    • Motzer, R.J.1    Michaelson, M.D.2    Redman, B.G.3
  • 8
    • 77949890945 scopus 로고    scopus 로고
    • Pazopanib in locally advanced or metastatic renal cell carcinoma: Results of a randomized phase III trial
    • Sternberg CN, Davis ID, Mardiak J, et al. Pazopanib in locally advanced or metastatic renal cell carcinoma: results of a randomized phase III trial. J Clin Oncol 2010;28(6):1061-1068
    • (2010) J Clin Oncol , vol.28 , Issue.6 , pp. 1061-1068
    • Sternberg, C.N.1    Davis, I.D.2    Mardiak, J.3
  • 9
    • 39049098974 scopus 로고    scopus 로고
    • Small molecule tyrosine kinase inhibitors: Potential role in pediatric malignant solid tumors
    • Rossler J, Geoerger B, Taylor M,Vassal G. Small molecule tyrosine kinase inhibitors: potential role in pediatric malignant solid tumors. Curr Cancer Drug Targets 2008;8(1):76-85
    • (2008) Curr Cancer Drug Targets , vol.8 , Issue.1 , pp. 76-85
    • Rossler, J.1    Geoerger, B.2    Taylor Mvassal, G.3
  • 10
    • 48349134168 scopus 로고    scopus 로고
    • Angiogenesis as a target in neuroblastoma
    • Rossler J, Taylor M, Geoerger B, et al. Angiogenesis as a target in neuroblastoma. Eur J Cancer 2008;44(12):1645-1656
    • (2008) Eur J Cancer , vol.44 , Issue.12 , pp. 1645-1656
    • Rossler, J.1    Taylor, M.2    Geoerger, B.3
  • 11
    • 20444412646 scopus 로고    scopus 로고
    • Therapeutic targeting of the tumor microenvironment
    • Joyce JA. Therapeutic targeting of the tumor microenvironment. Cancer Cell 2005;7(6):513-520
    • (2005) Cancer Cell , vol.7 , Issue.6 , pp. 513-520
    • Joyce, J.A.1
  • 12
  • 13
    • 0031019745 scopus 로고    scopus 로고
    • Isolation of putative progenitor endothelial cells for angiogenesis
    • Asahara T, Murohara T, Sullivan A, et al. Isolation of putative progenitor endothelial cells for angiogenesis. Science 1997;275(5302):964-967
    • (1997) Science , vol.275 , Issue.5302 , pp. 964-967
    • Asahara, T.1    Murohara, T.2    Sullivan, A.3
  • 14
    • 34250719709 scopus 로고    scopus 로고
    • Bone marrow-derived endothelial progenitor cells are a major determinant of nascent tumor neovascularization
    • Nolan DJ, Ciarrocchi A, Mellick AS, et al. Bone marrow-derived endothelial progenitor cells are a major determinant of nascent tumor neovascularization. Genes Dev 2007;21(12):1546-1558
    • (2007) Genes Dev , vol.21 , Issue.12 , pp. 1546-1558
    • Nolan, D.J.1    Ciarrocchi, A.2    Mellick, A.S.3
  • 15
    • 0035160312 scopus 로고    scopus 로고
    • Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth
    • Lyden D, Hattori K, Dias S, et al. Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth. Nat Med 2001;7(11):1194-1201
    • (2001) Nat Med , vol.7 , Issue.11 , pp. 1194-1201
    • Lyden, D.1    Hattori, K.2    Dias, S.3
  • 16
    • 20144386931 scopus 로고    scopus 로고
    • Contribution of bone marrow-derived endothelial cells to human tumor vasculature
    • Peters BA, Diaz LA, Polyak K, et al. Contribution of bone marrow-derived endothelial cells to human tumor vasculature. Nat Med 2005;11(3):261-262
    • (2005) Nat Med , vol.11 , Issue.3 , pp. 261-262
    • Peters, B.A.1    Diaz, L.A.2    Polyak, K.3
  • 17
    • 0142195911 scopus 로고    scopus 로고
    • Effect of angiogenesis inhibition by Id loss and the contribution of bone-marrow-derived endothelial cells in spontaneous murine tumors
    • Ruzinova MB, Schoer RA, Gerald W, et al. Effect of angiogenesis inhibition by Id loss and the contribution of bone-marrow-derived endothelial cells in spontaneous murine tumors. Cancer Cell 2003;4(4):277-289
    • (2003) Cancer Cell , vol.4 , Issue.4 , pp. 277-289
    • Ruzinova, M.B.1    Schoer, R.A.2    Gerald, W.3
  • 18
    • 33749005405 scopus 로고    scopus 로고
    • Therapy-induced acute recruitment of circulating endothelial progenitor cells to tumors
    • Shaked Y, Ciarrocchi A, Franco M, et al. Therapy-induced acute recruitment of circulating endothelial progenitor cells to tumors. Science 2006;313(5794):1785-1787
    • (2006) Science , vol.313 , Issue.5794 , pp. 1785-1787
    • Shaked, Y.1    Ciarrocchi, A.2    Franco, M.3
  • 19
    • 50349097617 scopus 로고    scopus 로고
    • Rapid chemotherapy-induced acute endothelial progenitor cell mobilization: Implications for antiangiogenic drugs as chemosensitizing agents
    • Shaked Y, Henke E, Roodhart JM, et al. Rapid chemotherapy-induced acute endothelial progenitor cell mobilization: implications for antiangiogenic drugs as chemosensitizing agents. Cancer Cell 2008;14(3):263-273
    • (2008) Cancer Cell , vol.14 , Issue.3 , pp. 263-273
    • Shaked, Y.1    Henke, E.2    Roodhart, J.M.3
  • 20
    • 34547617338 scopus 로고    scopus 로고
    • Antiangiogenic strategies on defense: On the possibility of blocking rebounds by the tumor vasculature after chemotherapy
    • Shaked Y, Kerbel RS. Antiangiogenic strategies on defense: on the possibility of blocking rebounds by the tumor vasculature after chemotherapy. Cancer Res 2007;67(15):7055-7058
    • (2007) Cancer Res , vol.67 , Issue.15 , pp. 7055-7058
    • Shaked, Y.1    Kerbel, R.S.2
  • 21
    • 0028114985 scopus 로고
    • The implications of angiogenesis for the biology and therapy of cancer metastasis
    • Fidler IJ, Ellis LM. The implications of angiogenesis for the biology and therapy of cancer metastasis. Cell 1994;79(2):185-188
    • (1994) Cell , vol.79 , Issue.2 , pp. 185-188
    • Fidler, I.J.1    Ellis, L.M.2
  • 22
    • 38149006909 scopus 로고    scopus 로고
    • Endothelial progenitor cells control the angiogenic switch in mouse lung metastasis
    • Gao D, Nolan DJ, Mellick AS, et al. Endothelial progenitor cells control the angiogenic switch in mouse lung metastasis. Science 2008;319(5860):195-198
    • (2008) Science , vol.319 , Issue.5860 , pp. 195-198
    • Gao, D.1    Nolan, D.J.2    Mellick, A.S.3
  • 23
    • 0036780251 scopus 로고    scopus 로고
    • Clinical translation of angiogenesis inhibitors
    • Kerbel R, Folkman J. Clinical translation of angiogenesis inhibitors. Nat Rev Cancer 2002;2(10):727-739
    • (2002) Nat Rev Cancer , vol.2 , Issue.10 , pp. 727-739
    • Kerbel, R.1    Folkman, J.2
  • 25
    • 0042343801 scopus 로고    scopus 로고
    • A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer
    • Yang JC, Haworth L, Sherry RM, et al. A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer. N Engl J Med 2003;349(5):427-434
    • (2003) N Engl J Med , vol.349 , Issue.5 , pp. 427-434
    • Yang, J.C.1    Haworth, L.2    Sherry, R.M.3
  • 26
    • 70350461699 scopus 로고    scopus 로고
    • Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma
    • Friedman HS, Prados MD, Wen PY, et al. Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma. J Clin Oncol 2009;27(28):4733-4740
    • (2009) J Clin Oncol , vol.27 , Issue.28 , pp. 4733-4740
    • Friedman, H.S.1    Prados, M.D.2    Wen, P.Y.3
  • 27
    • 11844254414 scopus 로고    scopus 로고
    • Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy
    • Jain RK. Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. Science 2005;307(5706):58-62
    • (2005) Science , vol.307 , Issue.5706 , pp. 58-62
    • Jain, R.K.1
  • 28
    • 47949099628 scopus 로고    scopus 로고
    • Modes of resistance to anti-angiogenic therapy
    • Bergers G, Hanahan D. Modes of resistance to anti-angiogenic therapy. Nat Rev Cancer 2008;8(8):592-603
    • (2008) Nat Rev Cancer , vol.8 , Issue.8 , pp. 592-603
    • Bergers, G.1    Hanahan, D.2
  • 29
    • 33749441325 scopus 로고    scopus 로고
    • Rapid vascular regrowth in tumors after reversal of VEGF inhibition
    • Mancuso MR, Davis R, Norberg SM, et al. Rapid vascular regrowth in tumors after reversal of VEGF inhibition. J Clin Invest 2006;116(10):2610-2621
    • (2006) J Clin Invest , vol.116 , Issue.10 , pp. 2610-2621
    • Mancuso, M.R.1    Davis, R.2    Norberg, S.M.3
  • 30
    • 60649106195 scopus 로고    scopus 로고
    • Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis
    • Paez-Ribes M, Allen E, Hudock J, et al. Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis. Cancer Cell 2009;15(3):220-231
    • (2009) Cancer Cell , vol.15 , Issue.3 , pp. 220-231
    • Paez-Ribes, M.1    Allen, E.2    Hudock, J.3
  • 31
    • 60649087564 scopus 로고    scopus 로고
    • Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis
    • Ebos JM, Lee CR, Cruz-Munoz W, et al. Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis. Cancer Cell 2009;15(3):232-239
    • (2009) Cancer Cell , vol.15 , Issue.3 , pp. 232-239
    • Ebos, J.M.1    Lee, C.R.2    Cruz-Munoz, W.3
  • 32
    • 46949084994 scopus 로고    scopus 로고
    • Biomarkers of angiogenesis for the development of antiangiogenic therapies in oncology: Tools or decorations?
    • Sessa C, Guibal A, Del Conte G, Ruegg C. Biomarkers of angiogenesis for the development of antiangiogenic therapies in oncology: tools or decorations? Nat Clin Pract Oncol 2008;5(7):378-391
    • (2008) Nat Clin Pract Oncol , vol.5 , Issue.7 , pp. 378-391
    • Sessa, C.1    Guibal, A.2    Del Conte, G.3    Ruegg, C.4
  • 33
    • 0037134709 scopus 로고    scopus 로고
    • Clinical application of antiangiogenic therapy: Microvessel density, what it does and doesn't tell us
    • Hlatky L, Hahnfeldt P, Folkman J. Clinical application of antiangiogenic therapy: microvessel density, what it does and doesn't tell us. J Natl Cancer Inst 2002;94(12):883-893
    • (2002) J Natl Cancer Inst , vol.94 , Issue.12 , pp. 883-893
    • Hlatky, L.1    Hahnfeldt, P.2    Folkman, J.3
  • 34
    • 0035865450 scopus 로고    scopus 로고
    • Clinical implications of circulating angiogenic factors in cancer patients
    • Poon RT, Fan ST, Wong J. Clinical implications of circulating angiogenic factors in cancer patients. J Clin Oncol 2001;19(4):1207-1225
    • (2001) J Clin Oncol , vol.19 , Issue.4 , pp. 1207-1225
    • Poon, R.T.1    Fan, S.T.2    Wong, J.3
  • 35
    • 33644823334 scopus 로고    scopus 로고
    • Impact of vascular endothelial growth factor-A expression, thrombospondin-2 expression, and microvessel density on the treatment effect of bevacizumab in metastatic colorectal cancer
    • Jubb AM, Hurwitz HI, Bai W, et al. Impact of vascular endothelial growth factor-A expression, thrombospondin-2 expression, and microvessel density on the treatment effect of bevacizumab in metastatic colorectal cancer. J Clin Oncol 2006;24(2):217-227
    • (2006) J Clin Oncol , vol.24 , Issue.2 , pp. 217-227
    • Jubb, A.M.1    Hurwitz, H.I.2    Bai, W.3
  • 36
    • 33746548452 scopus 로고    scopus 로고
    • Predicting benefit from anti-angiogenic agents in malignancy
    • Jubb AM, Oates AJ, Holden S, Koeppen H. Predicting benefit from anti-angiogenic agents in malignancy. Nat Rev Cancer 2006;6(8):626-635
    • (2006) Nat Rev Cancer , vol.6 , Issue.8 , pp. 626-635
    • Jubb, A.M.1    Oates, A.J.2    Holden, S.3    Koeppen, H.4
  • 37
    • 74949090109 scopus 로고    scopus 로고
    • Distinct patterns of cytokine and angiogenic factor modulation and markers of benefit for vandetanib and/or chemotherapy in patients with non-small-cell lung cancer
    • Hanrahan E, Lin H, Kim E, et al. Distinct patterns of cytokine and angiogenic factor modulation and markers of benefit for vandetanib and/or chemotherapy in patients with non-small-cell lung cancer. J Clin Oncol 2010;28(2):193-201
    • (2010) J Clin Oncol , vol.28 , Issue.2 , pp. 193-201
    • Hanrahan, E.1    Lin, H.2    Kim, E.3
  • 38
    • 74949105013 scopus 로고    scopus 로고
    • Biomarkers of antiangiogenic therapy: How do we move from candidate biomarkers to valid biomarkers?
    • Duda D, Ancukiewicz M, Jain R. Biomarkers of antiangiogenic therapy: how do we move from candidate biomarkers to valid biomarkers? J Clin Oncol 2010;28(2):183-185
    • (2010) J Clin Oncol , vol.28 , Issue.2 , pp. 183-185
    • Duda, D.1    Ancukiewicz, M.2    Jain, R.3
  • 39
    • 19944432454 scopus 로고    scopus 로고
    • Genetic heterogeneity of the vasculogenic phenotype parallels angiogenesis; Implications for cellular surrogate marker analysis of antiangiogenesis
    • Shaked Y, Bertolini F, Man S, et al. Genetic heterogeneity of the vasculogenic phenotype parallels angiogenesis; Implications for cellular surrogate marker analysis of antiangiogenesis. Cancer Cell 2005;7(1):101-111
    • (2005) Cancer Cell , vol.7 , Issue.1 , pp. 101-111
    • Shaked, Y.1    Bertolini, F.2    Man, S.3
  • 40
    • 33947540554 scopus 로고    scopus 로고
    • Detection of circulating endothelial cells: CD146-based magnetic separation enrichment or flow cytometric assay?
    • author reply e3-5
    • Dignat-George F, Sabatier F, Blann A, Woywodt A. Detection of circulating endothelial cells: CD146-based magnetic separation enrichment or flow cytometric assay? J Clin Oncol 2007;25(5):e1-2, author reply e3-5
    • (2007) J Clin Oncol , vol.25 , Issue.5
    • Dignat-George, F.1    Sabatier, F.2    Blann, A.3    Woywodt, A.4
  • 41
    • 0035383784 scopus 로고    scopus 로고
    • Resting and activated endothelial cells are increased in the peripheral blood of cancer patients
    • Mancuso P, Burlini A, Pruneri G, et al. Resting and activated endothelial cells are increased in the peripheral blood of cancer patients. Blood 2001;97(11):3658-3661
    • (2001) Blood , vol.97 , Issue.11 , pp. 3658-3661
    • Mancuso, P.1    Burlini, A.2    Pruneri, G.3
  • 42
    • 33745939679 scopus 로고    scopus 로고
    • Circulating endothelial-cell kinetics and viability predict survival in breast cancer patients receiving metronomic chemotherapy
    • Mancuso P, Colleoni M, Calleri A, et al. Circulating endothelial-cell kinetics and viability predict survival in breast cancer patients receiving metronomic chemotherapy. Blood 2006;108(2):452-459
    • (2006) Blood , vol.108 , Issue.2 , pp. 452-459
    • Mancuso, P.1    Colleoni, M.2    Calleri, A.3
  • 43
    • 33750286135 scopus 로고    scopus 로고
    • The multifaceted circulating endothelial cell in cancer: Towards marker and target identification
    • Bertolini F, Shaked Y, Mancuso P, Kerbel RS. The multifaceted circulating endothelial cell in cancer: towards marker and target identification. Nat Rev Cancer 2006;6(11):835-845
    • (2006) Nat Rev Cancer , vol.6 , Issue.11 , pp. 835-845
    • Bertolini, F.1    Shaked, Y.2    Mancuso, P.3    Kerbel, R.S.4
  • 44
    • 0026583956 scopus 로고
    • Rapid isolation of human endothelial cells from whole blood using S-Endo1 monoclonal antibody coupled to immuno-magnetic beads: Demonstration of endothelial injury after angioplasty
    • George F, Brisson C, Poncelet P, et al. Rapid isolation of human endothelial cells from whole blood using S-Endo1 monoclonal antibody coupled to immuno-magnetic beads: demonstration of endothelial injury after angioplasty. Thromb Haemost 1992;67(1):147-153
    • (1992) Thromb Haemost , vol.67 , Issue.1 , pp. 147-153
    • George, F.1    Brisson, C.2    Poncelet, P.3
  • 45
    • 58849156504 scopus 로고    scopus 로고
    • Validation of a standardized method for enumerating circulating endothelial cells and progenitors: Flow cytometry and molecular and ultrastructural analyses
    • Mancuso P, Antoniotti P, Quarna J, et al. Validation of a standardized method for enumerating circulating endothelial cells and progenitors: flow cytometry and molecular and ultrastructural analyses. Clin Cancer Res 2009;15(1):267-273
    • (2009) Clin Cancer Res , vol.15 , Issue.1 , pp. 267-273
    • Mancuso, P.1    Antoniotti, P.2    Quarna, J.3
  • 46
    • 33847623821 scopus 로고    scopus 로고
    • Cells meeting our immunophenotypic criteria of endothelial cells are large platelets
    • Strijbos MH, Kraan J, den Bakker MA, et al. Cells meeting our immunophenotypic criteria of endothelial cells are large platelets. Cytometry B Clin Cytom 2007;72(2):86-93
    • (2007) Cytometry B Clin Cytom , vol.72 , Issue.2 , pp. 86-93
    • Strijbos, M.H.1    Kraan, J.2    Den Bakker, M.A.3
  • 47
    • 66149184410 scopus 로고    scopus 로고
    • Quantification of circulating endothelial cells by flow cytometry
    • author reply-1
    • Strijbos MH, Kraan J, Lamers CH, et al. Quantification of circulating endothelial cells by flow cytometry. Clin Cancer Res 2009;15(10):3640, author reply-1
    • (2009) Clin Cancer Res , vol.15 , Issue.10 , pp. 3640
    • Strijbos, M.H.1    Kraan, J.2    Lamers, C.H.3
  • 48
    • 38649105118 scopus 로고    scopus 로고
    • Phase i trial and pharmacokinetic study of bevacizumab in pediatric patients with refractory solid tumors: A Children's Oncology Group Study
    • Glade Bender JL, Adamson PC, Reid JM, et al. Phase I trial and pharmacokinetic study of bevacizumab in pediatric patients with refractory solid tumors: a Children's Oncology Group Study. J Clin Oncol 2008;26(3):399-405
    • (2008) J Clin Oncol , vol.26 , Issue.3 , pp. 399-405
    • Glade Bender, J.L.1    Adamson, P.C.2    Reid, J.M.3
  • 49
    • 49449113237 scopus 로고    scopus 로고
    • Quantification of circulating mature endothelial cells using a whole blood four-color flow cytometric assay
    • Jacques N, Vimond N, Conforti R, et al. Quantification of circulating mature endothelial cells using a whole blood four-color flow cytometric assay. J Immunol Methods 2008;337(2):132-143
    • (2008) J Immunol Methods , vol.337 , Issue.2 , pp. 132-143
    • Jacques, N.1    Vimond, N.2    Conforti, R.3
  • 50
    • 68049102313 scopus 로고    scopus 로고
    • High levels of circulating VEGFR2+ Bone marrow-derived progenitor cells correlate with metastatic disease in patients with pediatric solid malignancies
    • Taylor M, Rossler J, Geoerger B, et al. High levels of circulating VEGFR2+ Bone marrow-derived progenitor cells correlate with metastatic disease in patients with pediatric solid malignancies. Clin Cancer Res 2009;15(14):4561-4571
    • (2009) Clin Cancer Res , vol.15 , Issue.14 , pp. 4561-4571
    • Taylor, M.1    Rossler, J.2    Geoerger, B.3
  • 51
    • 70350220627 scopus 로고    scopus 로고
    • Contribution of granulocyte colony-stimulating factor to the acute mobilization of endothelial precursor cells by vascular disrupting agents
    • Shaked Y, Tang T, Woloszynek J, et al. Contribution of granulocyte colony-stimulating factor to the acute mobilization of endothelial precursor cells by vascular disrupting agents. Cancer Res 2009;69(19):7524-7528
    • (2009) Cancer Res , vol.69 , Issue.19 , pp. 7524-7528
    • Shaked, Y.1    Tang, T.2    Woloszynek, J.3
  • 52
    • 34548157178 scopus 로고    scopus 로고
    • Vascular disrupting therapy-induced mobilization of circulating endothelial progenitor cells
    • Farace F, Massard C, Borghi E, et al. Vascular disrupting therapy-induced mobilization of circulating endothelial progenitor cells. Ann Oncol 2007;18(8):1421-1422
    • (2007) Ann Oncol , vol.18 , Issue.8 , pp. 1421-1422
    • Farace, F.1    Massard, C.2    Borghi, E.3
  • 53
    • 73949130004 scopus 로고    scopus 로고
    • Late release of circulating endothelial cells and endothelial progenitor cells after chemotherapy predicts response and survival in cancer patients
    • Roodhart JM, Langenberg MH, Vermaat JS, et al. Late release of circulating endothelial cells and endothelial progenitor cells after chemotherapy predicts response and survival in cancer patients. Neoplasia 2010;12(1):87-94
    • (2010) Neoplasia , vol.12 , Issue.1 , pp. 87-94
    • Roodhart, J.M.1    Langenberg, M.H.2    Vermaat, J.S.3
  • 54
    • 54449099774 scopus 로고    scopus 로고
    • Metronomic cyclophosphamide and capecitabine combined with bevacizumab in advanced breast cancer
    • Dellapasqua S, Bertolini F, Bagnardi V, et al. Metronomic cyclophosphamide and capecitabine combined with bevacizumab in advanced breast cancer. J Clin Oncol 2008;26(30):4899-4905
    • (2008) J Clin Oncol , vol.26 , Issue.30 , pp. 4899-4905
    • Dellapasqua, S.1    Bertolini, F.2    Bagnardi, V.3
  • 55
    • 73349127099 scopus 로고    scopus 로고
    • Predictive potential of angiogenic growth factors and circulating endothelial cells in breast cancer patients receiving metronomic chemotherapy plus bevacizumab
    • Calleri A, Bono A, Bagnardi V, et al. Predictive potential of angiogenic growth factors and circulating endothelial cells in breast cancer patients receiving metronomic chemotherapy plus bevacizumab. Clin Cancer Res 2009;15(24):7652-7657
    • (2009) Clin Cancer Res , vol.15 , Issue.24 , pp. 7652-7657
    • Calleri, A.1    Bono, A.2    Bagnardi, V.3
  • 56
    • 0030034892 scopus 로고    scopus 로고
    • Tumor angiogenesis correlates with metastatic disease, N-myc amplification, and poor outcome in human neuroblastoma
    • Meitar D, Crawford SE, Rademaker AW, Cohn SL. Tumor angiogenesis correlates with metastatic disease, N-myc amplification, and poor outcome in human neuroblastoma. J Clin Oncol 1996;14(2):405-414
    • (1996) J Clin Oncol , vol.14 , Issue.2 , pp. 405-414
    • Meitar, D.1    Crawford, S.E.2    Rademaker, A.W.3    Cohn, S.L.4
  • 57
    • 29644441444 scopus 로고    scopus 로고
    • Anti-angiogenic therapy in pediatric neuro-oncology
    • Kieran MW. Anti-angiogenic therapy in pediatric neuro-oncology. J Neurooncol 2005;75(3):327-334
    • (2005) J Neurooncol , vol.75 , Issue.3 , pp. 327-334
    • Kieran, M.W.1
  • 58
    • 0027197245 scopus 로고
    • Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo
    • Kim KJ, Li B, Winer J, et al. Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo. Nature 1993;362(6423):841-844
    • (1993) Nature , vol.362 , Issue.6423 , pp. 841-844
    • Kim, K.J.1    Li, B.2    Winer, J.3
  • 59
    • 0033979730 scopus 로고    scopus 로고
    • Anti-VEGF antibody suppresses primary tumor growth and metastasis in an experimental model of Wilms' tumor
    • discussion 2-3
    • Rowe DH, Huang J, Kayton ML, et al. Anti-VEGF antibody suppresses primary tumor growth and metastasis in an experimental model of Wilms' tumor. J Pediatr Surg 2000;35(1):30-2, discussion 2-3
    • (2000) J Pediatr Surg , vol.35 , Issue.1 , pp. 30-2
    • Rowe, D.H.1    Huang, J.2    Kayton, M.L.3
  • 60
    • 0037143739 scopus 로고    scopus 로고
    • Potent VEGF blockade causes regression of coopted vessels in a model of neuroblastoma
    • Kim ES, Serur A, Huang J, et al. Potent VEGF blockade causes regression of coopted vessels in a model of neuroblastoma. Proc Natl Acad Sci USA 2002;99(17):11399-11404
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.17 , pp. 11399-11404
    • Kim, E.S.1    Serur, A.2    Huang, J.3
  • 61
    • 0037370294 scopus 로고    scopus 로고
    • Anti-VEGF antibody in experimental hepatoblastoma: Suppression of tumor growth and altered angiogenesis
    • discussion-14
    • McCrudden KW, Hopkins B, Frischer J, et al. Anti-VEGF antibody in experimental hepatoblastoma: suppression of tumor growth and altered angiogenesis. J Pediatr Surg 2003;38(3):308-314, discussion-14
    • (2003) J Pediatr Surg , vol.38 , Issue.3 , pp. 308-314
    • McCrudden, K.W.1    Hopkins, B.2    Frischer, J.3
  • 62
    • 0036191974 scopus 로고    scopus 로고
    • Distinct response of experimental neuroblastoma to combination antiangiogenic strategies
    • Kim ES, Soffer SZ, Huang J, et al. Distinct response of experimental neuroblastoma to combination antiangiogenic strategies. J Pediatr Surg 2002;37(3):518-522
    • (2002) J Pediatr Surg , vol.37 , Issue.3 , pp. 518-522
    • Kim, E.S.1    Soffer, S.Z.2    Huang, J.3
  • 63
    • 0034894341 scopus 로고    scopus 로고
    • Combination antiangiogenic therapy: Increased efficacy in a murine model of Wilms tumor
    • Soffer SZ, Moore JT, Kim E, et al. Combination antiangiogenic therapy: increased efficacy in a murine model of Wilms tumor. J Pediatr Surg 2001;36(8):1177-1181
    • (2001) J Pediatr Surg , vol.36 , Issue.8 , pp. 1177-1181
    • Soffer, S.Z.1    Moore, J.T.2    Kim, E.3
  • 64
    • 0034087691 scopus 로고    scopus 로고
    • Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained tumor regression without overt toxicity
    • Klement G, Baruchel S, Rak J, et al. Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained tumor regression without overt toxicity. J Clin Invest 2000;105(8):R15-24
    • (2000) J Clin Invest , vol.105 , Issue.8
    • Klement, G.1    Baruchel, S.2    Rak, J.3
  • 65
    • 0035166387 scopus 로고    scopus 로고
    • Gene therapy-mediated expression by tumor cells of the angiogenesis inhibitor flk-1 results ininhibition of neuroblastoma growth in vivo
    • Davidoff AM, Leary MA, Ng CY, Vanin EF. Gene therapy-mediated expression by tumor cells of the angiogenesis inhibitor flk-1 results ininhibition of neuroblastoma growth in vivo. J Pediatr Surg 2001;36(1):30-36
    • (2001) J Pediatr Surg , vol.36 , Issue.1 , pp. 30-36
    • Davidoff, A.M.1    Leary, M.A.2    Ng, C.Y.3    Vanin, E.F.4
  • 66
    • 23944524789 scopus 로고    scopus 로고
    • Antitumor activity of imatinib mesylate in neuroblastoma xenografts
    • Meco D, Riccardi A, Servidei T, et al. Antitumor activity of imatinib mesylate in neuroblastoma xenografts. Cancer Lett 2005;228(1-2):211-219
    • (2005) Cancer Lett , vol.228 , Issue.1-2 , pp. 211-219
    • Meco, D.1    Riccardi, A.2    Servidei, T.3
  • 67
    • 29244438974 scopus 로고    scopus 로고
    • STI571 (Gleevec) improves tumor growth delay and survival in irradiated mouse models of glioblastoma
    • Geng L, Shinohara ET, Kim D, et al. STI571 (Gleevec) improves tumor growth delay and survival in irradiated mouse models of glioblastoma. Int J Radiat Oncol Biol Phys 2006;64(1):263-271
    • (2006) Int J Radiat Oncol Biol Phys , vol.64 , Issue.1 , pp. 263-271
    • Geng, L.1    Shinohara, E.T.2    Kim, D.3
  • 68
    • 0842323936 scopus 로고    scopus 로고
    • Effect of imatinib mesylate on neuroblastoma tumorigenesis and vascular endothelial growth factor expression
    • Beppu K, Jaboine J, Merchant MS, et al. Effect of imatinib mesylate on neuroblastoma tumorigenesis and vascular endothelial growth factor expression. J Natl Cancer Inst 2004;96(1):46-55
    • (2004) J Natl Cancer Inst , vol.96 , Issue.1 , pp. 46-55
    • Beppu, K.1    Jaboine, J.2    Merchant, M.S.3
  • 69
    • 0037146220 scopus 로고    scopus 로고
    • Potential use of imatinib in Ewing's Sarcoma: Evidence for in vitro and in vivo activity
    • Merchant MS, Woo CW, Mackall CL, Thiele CJ. Potential use of imatinib in Ewing's Sarcoma: evidence for in vitro and in vivo activity. J Natl Cancer Inst 2002;94(22):1673-1679
    • (2002) J Natl Cancer Inst , vol.94 , Issue.22 , pp. 1673-1679
    • Merchant, M.S.1    Woo, C.W.2    MacKall, C.L.3    Thiele, C.J.4
  • 70
    • 65949125105 scopus 로고    scopus 로고
    • In vivo antitumor and antimetastatic activity of sunitinib in preclinical neuroblastoma mouse model
    • Zhang L, Smith KM, Chong AL, et al. In vivo antitumor and antimetastatic activity of sunitinib in preclinical neuroblastoma mouse model. Neoplasia 2009;11(5):426-435
    • (2009) Neoplasia , vol.11 , Issue.5 , pp. 426-435
    • Zhang, L.1    Smith, K.M.2    Chong, A.L.3
  • 71
    • 0037349934 scopus 로고    scopus 로고
    • Improved effect of an antiangiogenic tyrosine kinase inhibitor (SU5416) by combinations with fractionated radiotherapy or low molecular weight heparin
    • Lund EL, Olsen MW, Lipson KE, et al. Improved effect of an antiangiogenic tyrosine kinase inhibitor (SU5416) by combinations with fractionated radiotherapy or low molecular weight heparin. Neoplasia 2003;5(2):155-160
    • (2003) Neoplasia , vol.5 , Issue.2 , pp. 155-160
    • Lund, E.L.1    Olsen, M.W.2    Lipson, K.E.3
  • 72
    • 0038476590 scopus 로고    scopus 로고
    • Pharmacodynamic-mediated effects of the angiogenesis inhibitor SU5416 on the tumor disposition of temozolomide in subcutaneous and intracerebral glioma xenograft models
    • Ma J, Li S, Reed K, et al. Pharmacodynamic-mediated effects of the angiogenesis inhibitor SU5416 on the tumor disposition of temozolomide in subcutaneous and intracerebral glioma xenograft models. J Pharmacol Exp Ther 2003;305(3):833-839
    • (2003) J Pharmacol Exp Ther , vol.305 , Issue.3 , pp. 833-839
    • Ma, J.1    Li, S.2    Reed, K.3
  • 73
    • 33846992324 scopus 로고    scopus 로고
    • Phase II study of thalidomide and radiation in children with newly diagnosed brain stem gliomas and glioblastoma multiforme
    • Turner CD, Chi S, Marcus KJ, et al. Phase II study of thalidomide and radiation in children with newly diagnosed brain stem gliomas and glioblastoma multiforme. J Neurooncol 2007;82(1):95-101
    • (2007) J Neurooncol , vol.82 , Issue.1 , pp. 95-101
    • Turner, C.D.1    Chi, S.2    Marcus, K.J.3
  • 74
    • 34547747328 scopus 로고    scopus 로고
    • A phase II trial of thalidomide and cyclophosphamide in patients with recurrent or refractory pediatric malignancies
    • Gilheeney SW, Lyden DC, Sgouros S, et al. A phase II trial of thalidomide and cyclophosphamide in patients with recurrent or refractory pediatric malignancies. Pediatr Blood Cancer 2007;49(3):261-265
    • (2007) Pediatr Blood Cancer , vol.49 , Issue.3 , pp. 261-265
    • Gilheeney, S.W.1    Lyden, D.C.2    Sgouros, S.3
  • 75
    • 37549041711 scopus 로고    scopus 로고
    • A phase II study of imatinib mesylate in children with refractory or relapsed solid tumors: A Children's Oncology Group study
    • Bond M, Bernstein ML, Pappo A, et al. A phase II study of imatinib mesylate in children with refractory or relapsed solid tumors: a Children's Oncology Group study. Pediatr Blood Cancer 2008;50(2):254-258
    • (2008) Pediatr Blood Cancer , vol.50 , Issue.2 , pp. 254-258
    • Bond, M.1    Bernstein, M.L.2    Pappo, A.3
  • 76
    • 59449108256 scopus 로고    scopus 로고
    • Phase i study of SU5416, a small molecule inhibitor of the vascular endothelial growth factor receptor (VEGFR) in refractory pediatric central nervous system tumors
    • Kieran MW, Supko JG, Wallace D, et al. Phase I study of SU5416, a small molecule inhibitor of the vascular endothelial growth factor receptor (VEGFR) in refractory pediatric central nervous system tumors. Pediatr Blood Cancer 2009;52(2):169-176
    • (2009) Pediatr Blood Cancer , vol.52 , Issue.2 , pp. 169-176
    • Kieran, M.W.1    Supko, J.G.2    Wallace, D.3
  • 77
    • 67650397808 scopus 로고    scopus 로고
    • Small molecule inhibitors in children with malignant gliomas
    • Herrington B, Kieran MW. Small molecule inhibitors in children with malignant gliomas. Pediatr Blood Cancer 2009;53(3):312-317
    • (2009) Pediatr Blood Cancer , vol.53 , Issue.3 , pp. 312-317
    • Herrington, B.1    Kieran, M.W.2
  • 78
    • 41549107098 scopus 로고    scopus 로고
    • Compassionate use of bevacizumab (Avastin) in children and young adults with refractory or recurrent solid tumors
    • Benesch M, Windelberg M, Sauseng W, et al. Compassionate use of bevacizumab (Avastin) in children and young adults with refractory or recurrent solid tumors. Ann Oncol 2008;19(4):807-813
    • (2008) Ann Oncol , vol.19 , Issue.4 , pp. 807-813
    • Benesch, M.1    Windelberg, M.2    Sauseng, W.3
  • 79
    • 66749085796 scopus 로고    scopus 로고
    • Objective response of multiply recurrent low-grade gliomas to bevacizumab and irinotecan
    • Packer RJ, Jakacki R, Horn M, et al. Objective response of multiply recurrent low-grade gliomas to bevacizumab and irinotecan. Pediatr Blood Cancer 2009;52(7):791-795
    • (2009) Pediatr Blood Cancer , vol.52 , Issue.7 , pp. 791-795
    • Packer, R.J.1    Jakacki, R.2    Horn, M.3
  • 83
    • 2942615257 scopus 로고    scopus 로고
    • The anti-angiogenic basis of metronomic chemotherapy
    • Kerbel RS, Kamen BA. The anti-angiogenic basis of metronomic chemotherapy. Nat Rev Cancer 2004;4(6):423-436
    • (2004) Nat Rev Cancer , vol.4 , Issue.6 , pp. 423-436
    • Kerbel, R.S.1    Kamen, B.A.2
  • 84
    • 0034032882 scopus 로고    scopus 로고
    • Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drug-resistant cancer
    • Browder T, Butterfield CE, Kraling BM, et al. Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drug-resistant cancer. Cancer Res 2000;60(7):1878-1886
    • (2000) Cancer Res , vol.60 , Issue.7 , pp. 1878-1886
    • Browder, T.1    Butterfield, C.E.2    Kraling, B.M.3
  • 85
    • 67349094407 scopus 로고    scopus 로고
    • Improving conventional or low dose metronomic chemotherapy with targeted antiangiogenic drugs
    • Kerbel RS. Improving conventional or low dose metronomic chemotherapy with targeted antiangiogenic drugs. Cancer Res Treat 2007;39(4):150-159
    • (2007) Cancer Res Treat , vol.39 , Issue.4 , pp. 150-159
    • Kerbel, R.S.1
  • 86
    • 67650422499 scopus 로고    scopus 로고
    • Antiangiogenic (metronomic) chemotherapy for brain tumors: Current and future perspectives
    • Samuel DP, Wen PY, Kieran MW. Antiangiogenic (metronomic) chemotherapy for brain tumors: current and future perspectives. Expert Opin Investig Drugs 2009;18(7):973-983
    • (2009) Expert Opin Investig Drugs , vol.18 , Issue.7 , pp. 973-983
    • Samuel, D.P.1    Wen, P.Y.2    Kieran, M.W.3
  • 87
    • 33745291938 scopus 로고    scopus 로고
    • Metronomic dosing of chemotherapy: Applications in pediatric oncology
    • Stempak D, Seely D, Baruchel S. Metronomic dosing of chemotherapy: applications in pediatric oncology. Cancer Invest 2006;24(4):432-443
    • (2006) Cancer Invest , vol.24 , Issue.4 , pp. 432-443
    • Stempak, D.1    Seely, D.2    Baruchel, S.3
  • 88
    • 33745783111 scopus 로고    scopus 로고
    • Combined biodifferentiating and antiangiogenic oral metronomic therapy is feasible and effective in relapsed solid tumors in children: Single-center pilot study
    • Sterba J, Valik D, Mudry P, et al. Combined biodifferentiating and antiangiogenic oral metronomic therapy is feasible and effective in relapsed solid tumors in children: single-center pilot study. Onkologie 2006;29(7):308-313
    • (2006) Onkologie , vol.29 , Issue.7 , pp. 308-313
    • Sterba, J.1    Valik, D.2    Mudry, P.3
  • 89
    • 33751218313 scopus 로고    scopus 로고
    • A pilot pharmacokinetic and antiangiogenic biomarker study of celecoxib and low-dose metronomic vinblastine or cyclophosphamide in pediatric recurrent solid tumors
    • Stempak D, Gammon J, Halton J, et al. A pilot pharmacokinetic and antiangiogenic biomarker study of celecoxib and low-dose metronomic vinblastine or cyclophosphamide in pediatric recurrent solid tumors. J Pediatr Hematol Oncol 2006;28(11):720-728
    • (2006) J Pediatr Hematol Oncol , vol.28 , Issue.11 , pp. 720-728
    • Stempak, D.1    Gammon, J.2    Halton, J.3
  • 90
    • 49949097870 scopus 로고    scopus 로고
    • Phase II study of metronomic chemotherapy with thalidomide, carboplatin-vincristine-fluvastatin in the treatment of brain stem tumors in children
    • Lopez-Aguilar E, Sepulveda-Vildosola AC, Betanzos-Cabrera Y, et al. Phase II study of metronomic chemotherapy with thalidomide, carboplatin-vincristine- fluvastatin in the treatment of brain stem tumors in children. Arch Med Res 2008;39(7):655-662
    • (2008) Arch Med Res , vol.39 , Issue.7 , pp. 655-662
    • Lopez-Aguilar, E.1    Sepulveda-Vildosola, A.C.2    Betanzos-Cabrera, Y.3
  • 91
    • 32944474182 scopus 로고    scopus 로고
    • VEGF-dependent plasticity of fenestrated capillaries in the normal adult microvasculature
    • Kamba T, Tam BY, Hashizume H, et al. VEGF-dependent plasticity of fenestrated capillaries in the normal adult microvasculature. Am J Physiol Heart Circ Physiol 2006;290(2):H560-76
    • (2006) Am J Physiol Heart Circ Physiol , vol.290 , Issue.2
    • Kamba, T.1    Tam, B.Y.2    Hashizume, H.3
  • 92
    • 23444435294 scopus 로고    scopus 로고
    • Clinical implications of antiangiogenic therapies
    • Williston Park
    • Hudis CA. Clinical implications of antiangiogenic therapies. Oncology (Williston Park) 2005;19(4 Suppl 3):26-31
    • (2005) Oncology , vol.19 , Issue.4 SUPPL. 3 , pp. 26-31
    • Hudis, C.A.1
  • 93
    • 0036031829 scopus 로고    scopus 로고
    • G-CSF stimulates angiogenesis and promotes tumor growth: Potential contribution of bone marrow-derived endothelial progenitor cells
    • Natori T, Sata M, Washida M, et al. G-CSF stimulates angiogenesis and promotes tumor growth: potential contribution of bone marrow-derived endothelial progenitor cells. Biochem Biophys Res Commun 2002;297(4):1058-1061
    • (2002) Biochem Biophys Res Commun , vol.297 , Issue.4 , pp. 1058-1061
    • Natori, T.1    Sata, M.2    Washida, M.3
  • 94
    • 0342683814 scopus 로고    scopus 로고
    • The angiogenesis inhibitor TNP-470 reduces the growth rate of human neuroblastoma in nude rats
    • Wassberg E, Pahlman S, Westlin JE, Christofferson R. The angiogenesis inhibitor TNP-470 reduces the growth rate of human neuroblastoma in nude rats. Pediatr Res 1997;41(3):327-333
    • (1997) Pediatr Res , vol.41 , Issue.3 , pp. 327-333
    • Wassberg, E.1    Pahlman, S.2    Westlin, J.E.3    Christofferson, R.4
  • 95
    • 0033378227 scopus 로고    scopus 로고
    • Effectiveness of the angiogenesis inhibitor TNP-470 in reducing the growth of human neuroblastoma in nude mice inversely correlates with tumor burden
    • Katzenstein HM, Rademaker AW, Senger C, et al. Effectiveness of the angiogenesis inhibitor TNP-470 in reducing the growth of human neuroblastoma in nude mice inversely correlates with tumor burden. Clin Cancer Res 1999;5(12):4273-4278
    • (1999) Clin Cancer Res , vol.5 , Issue.12 , pp. 4273-4278
    • Katzenstein, H.M.1    Rademaker, A.W.2    Senger, C.3
  • 96
    • 3042710724 scopus 로고    scopus 로고
    • Thalidomide is anti-angiogenic in a xenograft model of neuroblastoma
    • Kaicker S, McCrudden KW, Beck L, et al. Thalidomide is anti-angiogenic in a xenograft model of neuroblastoma. Int J Oncol 2003;23(6):1651-1655
    • (2003) Int J Oncol , vol.23 , Issue.6 , pp. 1651-1655
    • Kaicker, S.1    McCrudden, K.W.2    Beck, L.3
  • 97
    • 33644803579 scopus 로고    scopus 로고
    • Combination treatment with temozolomide and thalidomide inhibits tumor growth and angiogenesis in an orthotopic glioma model
    • Son MJ, Kim JS, Kim MH, et al. Combination treatment with temozolomide and thalidomide inhibits tumor growth and angiogenesis in an orthotopic glioma model. Int J Oncol 2006;28(1):53-59
    • (2006) Int J Oncol , vol.28 , Issue.1 , pp. 53-59
    • Son, M.J.1    Kim, J.S.2    Kim, M.H.3
  • 98
    • 10744225322 scopus 로고    scopus 로고
    • Continuous versus intermittent administration of human endostatin in xenografted human neuroblastoma
    • Kuroiwa M, Takeuchi T, Lee JH, et al. Continuous versus intermittent administration of human endostatin in xenografted human neuroblastoma. J Pediatr Surg 2003;38(10):1499-1505
    • (2003) J Pediatr Surg , vol.38 , Issue.10 , pp. 1499-1505
    • Kuroiwa, M.1    Takeuchi, T.2    Lee, J.H.3
  • 99
    • 0242439573 scopus 로고    scopus 로고
    • High level of stabilized angiostatin mediated by adenovirus delivery does not impair the growth of human neuroblastoma xenografts
    • Joseph JM, Bouquet C, Opolon P, et al. High level of stabilized angiostatin mediated by adenovirus delivery does not impair the growth of human neuroblastoma xenografts. Cancer Gene Ther 2003;10(11):859-866
    • (2003) Cancer Gene Ther , vol.10 , Issue.11 , pp. 859-866
    • Joseph, J.M.1    Bouquet, C.2    Opolon, P.3
  • 100
    • 33847701595 scopus 로고    scopus 로고
    • Thrombospondin-1 peptide ABT-510 combined with valproic acid is an effective antiangiogenesis strategy in neuroblastoma
    • Yang Q, Tian Y, Liu S, et al. Thrombospondin-1 peptide ABT-510 combined with valproic acid is an effective antiangiogenesis strategy in neuroblastoma. Cancer Res 2007;67(4):1716-1724
    • (2007) Cancer Res , vol.67 , Issue.4 , pp. 1716-1724
    • Yang, Q.1    Tian, Y.2    Liu, S.3
  • 101
    • 77953408236 scopus 로고    scopus 로고
    • ITCC Phase II study of imatinib mesylate in children with solid tumors expressing imatinib-sensitive tyrosine kinase receptors
    • Vassal G, Geoerger B, Le Deley M, et al. ITCC Phase II study of imatinib mesylate in children with solid tumors expressing imatinib-sensitive tyrosine kinase receptors. J Clin Oncol, ASCO Meeting Abstracts 2006;24:9003
    • (2006) J Clin Oncol, ASCO Meeting Abstracts , vol.24 , pp. 9003
    • Vassal, G.1    Geoerger, B.2    Le Deley, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.