Kit-like 18F-labeling of RGD-19F-Arytrifluroborate in high yield and at extraordinarily high specific activity with preliminary in vivo tumor imaging

Nuclear Medicine and Biology

Volumn 40, Issue 6, 2013, Pages 841-849

  Liu, Zhibo ^a   Li, Ying ^a,c   Lozada, Jerome ^a   Wong, May Q ^b   Greene, Jennifer ^b   Lin, Kuo Shyan ^b   Yapp, Donald ^b   Perrin, David M ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b BRITISH COLUMBIA CANCER AGENCY   (Canada)

^c NANJING UNIVERSITY OF INFORMATION SCIENCE AND TECHNOLOGY   (China)

Author keywords

18F labeling; Methodology; New radiotracer development; Radiosynthesis; RGD

Indexed keywords

ARYTRIFLUROBORATE F 18; FLUORODEOXYGLUCOSE F 18; RADIOPHARMACEUTICAL AGENT; TRACER; UNCLASSIFIED DRUG; BORIC ACID; BORON DERIVATIVE; CYCLOPEPTIDE; DIAGNOSTIC AGENT; FLUORINE;

ANIMAL EXPERIMENT; ARTICLE; CANCER DIAGNOSIS; CANCER STAGING; CHEMICAL STRUCTURE; CONTROLLED STUDY; EX VIVO STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; IN VIVO STUDY; ISOTOPE LABELING; MOUSE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; (18)F-LABELING; ANIMAL; CELL TRANSFORMATION; CHEMISTRY; CLICK CHEMISTRY; GLIOBLASTOMA; METHODOLOGY; NEW RADIOTRACER DEVELOPMENT; PATHOLOGY; RADIOSYNTHESIS; RGD; SCINTISCANNING; TUMOR CELL LINE; DIAGNOSTIC USE; PROCEDURES;

(18)F-LABELING; METHODOLOGY; NEW RADIOTRACER DEVELOPMENT; RADIOSYNTHESIS; RGD;

ANIMALS; BORATES; BORON COMPOUNDS; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; CLICK CHEMISTRY; FLUORINE RADIOISOTOPES; GLIOBLASTOMA; HUMANS; ISOTOPE LABELING; MICE; PEPTIDES, CYCLIC; POSITRON-EMISSION TOMOGRAPHY;

EID: 84881031050     PISSN: 09698051     EISSN: 18729614     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2013.05.002     Document Type: Article

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