Click chemistry for 18F-labeling of RGD peptides and microPET imaging of tumor integrin αvβ3 expression

Bioconjugate Chemistry

Volumn 18, Issue 6, 2007, Pages 1987-1994

  Li, Zi Bo ^a   Wu, Zhanhong ^a,b   Chen, Kai ^a   Chin, Frederick T ^a   Chen, Xiaoyuan ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b PEKING UNION MEDICAL COLLEGE HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CELL ADHESION; COPPER COMPOUNDS; FLUORINE COMPOUNDS; HYDROCARBONS; METABOLISM; PEPTIDES;

CLICK CHEMISTRY; CLICK REACTION; HIGHER YIELD; INTEGRINS; LABELINGS; METABOLIC STABILITY; MICRO PETS; POST INJECTION; RGD PEPTIDE; SYNTHESISED;

TUMORS;

1,2,3 TRIAZOLE DERIVATIVE; ALKYNE DERIVATIVE; ARGINYLGLYCYLASPARTIC ACID; AZIDE; CUPROUS ION; FLUOROPOLYETHYLENEGLYCOL 1,2,3 TRIAZOLE ARGINYLGLYCYLASPARTIC ACID F 18; INTEGRIN; INTEGRIN ALPHA5 BETA3; TOLUENESULFONIC ACID DERIVATIVE; TRACER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CATALYSIS; CHEMICAL PROCEDURES; CHEMICAL REACTION; CONTROLLED STUDY; CYCLOADDITION; DRUG BINDING; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG METABOLISM; DRUG SPECIFICITY; DRUG STABILITY; DRUG SYNTHESIS; DRUG TARGETING; DRUG UPTAKE; DRUG URINE LEVEL; FEMALE; FLUORINATION; GLIOBLASTOMA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IC 50; IN VIVO STUDY; ISOTOPE LABELING; KIDNEY CLEARANCE; LIVER CLEARANCE; MOUSE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PROTEIN EXPRESSION; PURIFICATION; RADIOCHEMISTRY; TUMOR MODEL; TUMOR XENOGRAFT;

MURINAE;

EID: 36849012163     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc700226v     Document Type: Article

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