The PEG-fluorochrome shielding approach for targeted probe design

Journal of the American Chemical Society

Volumn 134, Issue 47, 2012, Pages 19338-19341

  Guo, Yanyan ^a   Yuan, Hushan ^a   Rice, William L ^a   Kumar, Anand T N ^a   Goergen, Craig J ^a   Jokivarsi, Kimmo ^a   Josephson, Lee ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLUORESCENT PROBES; FLUOROCHROMES; IN-VITRO; IN-VIVO; INTEGRINS; NEAR INFRARED; NON-SPECIFIC INTERACTIONS; PEGYLATION; PROBE DESIGN; SELF-QUENCHING;

BIOMOLECULES; DESIGN; FUNCTIONAL GROUPS; PEPTIDES; QUANTUM YIELD; SHIELDING;

PROBES;

ARGINYLALANYLASPARTIC ACID; ARGINYLALANYLASPARTIC ACID IN 111; ARGINYLGLYCYLASPARTIC ACID; ARGINYLGLYCYLASPARTIC ACID IN 111; FLUOROCHROME; INTEGRIN; MACROGOL; PEPTIDE DERIVATIVE; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHEMICAL REACTION; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG DESIGN; DRUG PROTEIN BINDING; DRUG SYNTHESIS; FLUORESCENCE ACTIVATED CELL SORTING; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR INTERACTION; MOLECULAR PROBE; MOUSE; NONHUMAN; PEGYLATION; PEPTIDE SYNTHESIS; PRODUCT DEVELOPMENT; QUANTUM YIELD; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY;

ANIMALS; CELL LINE, TUMOR; FLUORESCENT DYES; HUMANS; MICE; MOLECULAR PROBES; MOLECULAR STRUCTURE; PEPTIDES; POLYETHYLENE GLYCOLS;

EID: 84870321239     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja309085b     Document Type: Article

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