Improved 18F labeling of peptides with a fluoride-aluminum- chelate complex

Bioconjugate Chemistry

Volumn 21, Issue 7, 2010, Pages 1331-1340

  McBride, William J ^a   D'souza, Christopher A ^a   Sharkey, Robert M ^b   Karacay, Habibe ^b   Rossi, Edmund A ^c   Chang, Chien Hsing ^c   Goldenberg, David M ^b  

^a IMMUNOMEDICS INC   (United States)

^b IBC Pharmaceuticals Inc   (United States)

^c CENTER FOR MOLECULAR MEDICINE AND IMMUNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALUMINUM COMPOUNDS; CHROMATOGRAPHIC ANALYSIS; FLUORINE COMPOUNDS; LIGANDS; PURIFICATION;

CHELATE COMPLEX; FLUORINE-18; LABELINGS; ONE-POT METHOD; RADIOLABEL; RADIOLABELLING; REACTION CONDITIONS; REACTION REAGENTS; REAGENT CONCENTRATION; STRUCTURAL VARIATIONS;

PEPTIDES;

ALUMINUM; CHELATE; FLUORIDE; FLUORINE 18; IMP 449; IMP 460; IMP 461; IMP 467; METAL COMPLEX; PEPTIDE; UNCLASSIFIED DRUG; CHELATING AGENT; FLUORINE; LIGAND;

ARTICLE; CHEMICAL REACTION; CHROMATOGRAPHY; CONTROLLED STUDY; DRUG STABILITY; IN VITRO STUDY; IN VIVO STUDY; ISOTOPE LABELING; PROTEIN PURIFICATION; PROTEIN STABILITY; PROTEIN STRUCTURE; REACTION TIME; TEMPERATURE; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; HUMAN; KINETICS; MOUSE; NUDE MOUSE; PH; SYNTHESIS; TISSUE DISTRIBUTION;

ALUMINUM; ANIMALS; CHELATING AGENTS; FLUORIDES; FLUORINE RADIOISOTOPES; HUMANS; HYDROGEN-ION CONCENTRATION; KINETICS; LIGANDS; MICE; MICE, NUDE; MOLECULAR STRUCTURE; PEPTIDES; TISSUE DISTRIBUTION;

EID: 77954881828     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/bc100137x     Document Type: Article

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