Specific Imaging of Inflammation with the 18kDa Translocator Protein Ligand DPA-714 in Animal Models of Epilepsy and Stroke

PLoS ONE

Volumn 8, Issue 8, 2013, Pages

  Harhausen, Denise ^a,b   Sudmann, Violetta ^c   Khojasteh, Uldus ^a   Müller, Jochen ^a   Zille, Marietta ^a,b   Graham, Keith ^c   Thiele, Andrea ^c   Dyrks, Thomas ^c   Dirnagl, Ulrich ^a,b   Wunder, Andreas ^a,b  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b Center for Stroke Research Berlin CSB   (Germany)

^c Global Drug Discovery   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BENZODIAZEPINE RECEPTOR; FLUORINE DPA 714 F 18; TRACER; TRANSLOCATOR PROTEIN 18; TRITIUM DPA 714 H 3; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BINDING AFFINITY; BLOOD BRAIN BARRIER; CELL ACTIVATION; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; ENCEPHALITIS; EPILEPSY; IMMUNOHISTOCHEMISTRY; MACROPHAGE; MALE; MICROGLIA; MOLECULAR IMAGING; MOUSE; NONHUMAN; RAT;

ANIMALS; AUTORADIOGRAPHY; BLOOD-BRAIN BARRIER; CARRIER PROTEINS; CELLS, CULTURED; DISEASE MODELS, ANIMAL; EPILEPSY; FLUORINE RADIOISOTOPES; IMMUNOENZYME TECHNIQUES; INFLAMMATION; KAINIC ACID; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICROGLIA; POSITRON-EMISSION TOMOGRAPHY; PYRAZOLES; PYRIMIDINES; RADIOPHARMACEUTICALS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA; RECEPTORS, GABA-A; STROKE;

EID: 84881003411     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0069529     Document Type: Article

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