Imaging microglial/macrophage activation in spinal cords of experimental autoimmune encephalomyelitis rats by positron emission tomography using the mitochondrial 18 kDa translocator protein radioligand [18F]DPA-714

Journal of Neuroscience

Volumn 32, Issue 17, 2012, Pages 5728-5736

  Abourbeh, Galith ^a,b   Thézé, Benoit ^a,b   Maroy, Renaud ^b   Dubois, Albertine ^a,b   Brulon, Vincent ^b   Fontyn, Yoann ^b   Dollé, Frédéric ^b   Tavitian, Bertrand ^a,b   Boisgard, Raphaël ^a,b  

^a INSERM   (France)

^b SERVICE HOSPITALIER FRÉDÉRIC JOLIOT   (France)

Author keywords

[No Author keywords available]

Indexed keywords

[N,N DIETHYL 2 [2 [4 (2 FLUOROETHOXY)PHENYL] 5,7 DIMETHYLPYRAZOLO[1,5 A]PYRIMIDIN 3 YL]ACETAMIDE]; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL TRANSLOCATOR PROTEIN; RADIOLIGAND; UNCLASSIFIED DRUG;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CELL ACTIVATION; CONTROLLED STUDY; FEMALE; FUNCTIONAL NEUROIMAGING; IMAGING; IMMUNOHISTOCHEMISTRY; MACROPHAGE; MICROGLIA; MULTIPLE SCLEROSIS; NEUROGENIC INFLAMMATION; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RADIOACTIVITY; RAT; SPINAL CORD; WESTERN BLOTTING;

ANIMALS; ANTIGENS, CD; CARRIER PROTEINS; DISEASE MODELS, ANIMAL; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; FLUORINE RADIOISOTOPES; GLIAL FIBRILLARY ACIDIC PROTEIN; ISOQUINOLINES; MACROPHAGES; MICROGLIA; MYELIN BASIC PROTEIN; PEPTIDE FRAGMENTS; POSITRON-EMISSION TOMOGRAPHY; PYRAZOLES; PYRIMIDINES; RATS; RATS, INBRED LEW; RECEPTORS, GABA-A; SPINAL CORD; TIME FACTORS; TISSUE DISTRIBUTION;

EID: 84860157822     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2900-11.2012     Document Type: Article

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