The translocator protein ligand [ 18F]DPA-714 images glioma and activated microglia in vivo

European Journal of Nuclear Medicine and Molecular Imaging

Volumn 39, Issue 5, 2012, Pages 811-823

  Winkeler, Alexandra ^a,d   Boisgard, Raphael ^a,d   Awde, Ali R ^a,d   Dubois, Albertine ^a,d   Thézé, Benoit ^a,d   Zheng, Jinzi ^a,d   Ciobanu, Luisa ^b   Dollé, Frédéric ^d   Viel, Thomas ^c   Jacobs, Andreas H ^c   Tavitian, Bertrand ^a  

^a INSERM   (France)

^b DIF   (France)

^c UNIVERSITY OF MÜNSTER   (Germany)

^d SERVICE HOSPITALIER FRÉDÉRIC JOLIOT   (France)

Author keywords

18F DPA 714; Glioma; Microglia; Peripheral benzodiazepine receptor; Positron emission tomography; Translocator protein; TSPO

Indexed keywords

N SEC BUTYL 1 (2 CHLOROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE; N,N DIETHYL 2 [2 [4 [2 (18F)FLUOROETHOXY]PHENYL] 5,7 DIMEDIMETHYLPYRAZOLO[1,5 A]PYRIMIDIN 3 YL]ACETAMIDE; RADIOLIGAND; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GLIOMA; GLIOMA CELL; IN VITRO STUDY; IN VIVO STUDY; LIGAND BINDING; MICROGLIA; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; POSITRON EMISSION TOMOGRAPHY; RAT;

ANIMALS; BIOLOGICAL TRANSPORT; CELL LINE, TUMOR; FLUORINE RADIOISOTOPES; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOMA; KINETICS; LIGANDS; MICE; MICROGLIA; POSITRON-EMISSION TOMOGRAPHY; PYRAZOLES; PYRIMIDINES; RATS; RECEPTORS, GABA; SUBSTRATE SPECIFICITY;

EID: 84862581540     PISSN: 16197070     EISSN: 16197089     Source Type: Journal    
DOI: 10.1007/s00259-011-2041-4     Document Type: Article

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