Environmental toxin-linked nonalcoholic steatohepatitis and hepatic metabolic reprogramming in obese mice

Toxicological Sciences

Volumn 134, Issue 2, 2013, Pages 291-303

  Seth, Ratanesh Kumar ^a   Kumar, Ashutosh ^b   Das, Suvarthi ^a   Kadiiska, Maria B ^b   Michelotti, Gregory ^c   Diehl, Anna Mae ^c   Chatterjee, Saurabh ^a  

^a UNIVERSITY OF SOUTH CAROLINA   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^c DUKE UNIVERSITY   (United States)

Author keywords

Bromodichloromethane; Fibrosis; Gluconeogenesis; Glut 1; Glycolysis; Hepatocyte; Lipid peroxidation; Ob ob mice; PPAR ; SREBP 1C; Tumor necrosis factor

Indexed keywords

6 PHOSPHOFRUCTOKINASE; ALPHA SMOOTH MUSCLE ACTIN; BROMODICHLOROMETHANE; COLLAGEN; CYTOCHROME P450; TYROSINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARBOHYDRATE METABOLISM; CELL ACTIVATION; CONTROLLED STUDY; CYTOCHROME P450 2E1 GENE; DISEASE COURSE; GENE; GENE CONTROL; GENE EXPRESSION; GLUCOSE TRANSPORTER 1 GENE; GLUCOSE TRANSPORTER 4 GENE; KUPFFER CELL; LEPTIN GENE; LIPID DIET; LIPID METABOLISM; LIPID PEROXIDATION; LIVER METABOLISM; LIVER NECROSIS; MALE; MALLORY BODY; MOUSE; NITRATION; NONALCOHOLIC FATTY LIVER; NONHUMAN; OBESITY; OXIDATIVE STRESS; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA GENE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA GENE; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP) GENE; PROTEIN EXPRESSION; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C GENE; UNCOUPLING PROTEIN 1 GENE;

BROMODICHLOROMETHANE; FIBROSIS; GLUCONEOGENESIS; GLUT-1; GLYCOLYSIS; HEPATOCYTE; LIPID PEROXIDATION; OB/OB MICE.; PPAR-Γ; SREBP-1C; TUMOR NECROSIS FACTOR;

ANIMALS; CYTOCHROME P-450 CYP2E1; ENVIRONMENTAL POLLUTANTS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FATS; FATTY LIVER; GLUCOSE; LEPTIN; LIVER; MICE; MICE, KNOCKOUT; OBESITY; OXIDATIVE STRESS;

EID: 84880668528     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kft104     Document Type: Article

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