Leptin is key to peroxynitrite-mediated oxidative stress and Kupffer cell activation in experimental non-alcoholic steatohepatitis

Journal of Hepatology

Volumn 58, Issue 4, 2013, Pages 778-784

  Chatterjee, Saurabh ^a,b   Ganini, Douglas ^b   Tokar, Erik J ^b   Kumar, Ashutosh ^b   Das, Suvarthi ^a   Corbett, Jean ^b   Kadiiska, Maria B ^b   Waalkes, Michael P ^b   Diehl, Anna Mae ^c   Mason, Ronald P ^b  

^a UNIVERSITY OF SOUTH CAROLINA   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^c DUKE UNIVERSITY   (United States)

Author keywords

Adipocytokines; Kupffer cell; NADPH oxidase; ob ob mice; Oxidative stress; Tyrosine nitration

Indexed keywords

ALLOPURINOL; APOCYNIN; CARBON TETRACHLORIDE; FREE RADICAL; INDUCIBLE NITRIC OXIDE SYNTHASE; LEPTIN; LEPTIN ANTIBODY; MONOCYTE CHEMOTACTIC PROTEIN 1; N [3 (AMINOMETHYL)BENZYL]ACETAMIDINE; PEROXYNITRITE; PROTEIN ANTIBODY; PROTEIN P47; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD SAMPLING; CATALYST; CELL ACTIVATION; CONTROLLED STUDY; DECOMPOSITION; INFLAMMATION; KUPFFER CELL; LIPID DIET; MACROPHAGE; MALE; MEDIATOR; MOUSE; NONALCOHOLIC FATTY LIVER; NONHUMAN; OBESITY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SINGLE DRUG DOSE; SPIN TRAPPING;

ANIMALS; CYTOKINES; DISEASE MODELS, ANIMAL; FATTY LIVER; INFLAMMATION MEDIATORS; KUPFFER CELLS; LEPTIN; MALE; MICE; MICE, INBRED C57BL; NADPH OXIDASE; NITRIC OXIDE SYNTHASE TYPE II; OBESITY; OXIDATIVE STRESS; PEROXYNITROUS ACID;

EID: 84880948171     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2012.11.035     Document Type: Article

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