-
1
-
-
0033231294
-
Association of nonalcoholic fatty liver disease with insulin resistance
-
Marchesini G, Brizi M, Morselli-Labate AM, Bianchi G, Bugianesi E, McCullough AJ, et al. Association of nonalcoholic fatty liver disease with insulin resistance. Am J Med 1999;107:450-5.
-
(1999)
Am. J. Med.
, vol.107
, pp. 450-455
-
-
Marchesini, G.1
Brizi, M.2
Morselli-Labate, A.M.3
Bianchi, G.4
Bugianesi, E.5
McCullough, A.J.6
-
2
-
-
33645177980
-
Insulin resistance is an independent defect in non alcoholic steatohepatitis (NASH)
-
Vanni E, Bugianesi E, Gastaldelli A, Gambino R, Cassader M, Ponti V, et al. Insulin resistance is an independent defect in non alcoholic steatohepatitis (NASH). Hepatology 2001;34:361A.
-
(2001)
Hepatology
, vol.34
-
-
Vanni, E.1
Bugianesi, E.2
Gastaldelli, A.3
Gambino, R.4
Cassader, M.5
Ponti, V.6
-
4
-
-
0003774655
-
Preventing and managing the global epidemic: Report of a WHO consultation
-
World Health Organization. WHO Technical Report Series. Geneva: World Health Organization
-
World Health Organization. Preventing and managing the global epidemic: report of a WHO consultation. WHO Technical Report Series. Geneva: World Health Organization; 2000. p. 894.
-
(2000)
, pp. 894
-
-
-
5
-
-
0037223174
-
Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001
-
Mokdad AH, Ford ES, Bowman BA, Dietz WH, Vinicor F, Bales VS, et al. Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001. J Am Med Assoc 2003;289:76-9.
-
(2003)
J. Am. Med. Assoc.
, vol.289
, pp. 76-79
-
-
Mokdad, A.H.1
Ford, E.S.2
Bowman, B.A.3
Dietz, W.H.4
Vinicor, F.5
Bales, V.S.6
-
6
-
-
0037221394
-
Determinants of the association of overweight with elevated serum alanine aminotransferase activity in the United States
-
Ruhl CE, Everhart JE. Determinants of the association of overweight with elevated serum alanine aminotransferase activity in the United States. Gastroenterology 2003;124:71-9.
-
(2003)
Gastroenterology
, vol.124
, pp. 71-79
-
-
Ruhl, C.E.1
Everhart, J.E.2
-
7
-
-
0141594639
-
Is obesity a risk factor for cirrhosis-related death or hospitalization? A population-based cohort study
-
Ioannou GN, Weiss NS, Kowdley KV, Dominitz JA. Is obesity a risk factor for cirrhosis-related death or hospitalization? A population-based cohort study. Gastroenterology 2003;125:1053-9.
-
(2003)
Gastroenterology
, vol.125
, pp. 1053-1059
-
-
Ioannou, G.N.1
Weiss, N.S.2
Kowdley, K.V.3
Dominitz, J.A.4
-
8
-
-
0037464510
-
Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults
-
Calle EE, Rodriguez C, Walker-Thurmond K, Thun MJ. Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. N Engl J Med 2003;348:1625-38.
-
(2003)
N. Engl. J. Med.
, vol.348
, pp. 1625-1638
-
-
Calle, E.E.1
Rodriguez, C.2
Walker-Thurmond, K.3
Thun, M.J.4
-
9
-
-
0033329864
-
Liver pathology and the metabolic syndrome X in severe obesity
-
Marceau P, Biron S, Hould FS, Marceau S, Simard S, Thung SN, et al. Liver pathology and the metabolic syndrome X in severe obesity. J Clin Endocrinol Metab 1999;84:1513-7.
-
(1999)
J. Clin. Endocrinol. Metab.
, vol.84
, pp. 1513-1517
-
-
Marceau, P.1
Biron, S.2
Hould, F.S.3
Marceau, S.4
Simard, S.5
Thung, S.N.6
-
10
-
-
0034116558
-
Liver fibrosis in overweight patients
-
Ratziu V, Giral P, Charlotte F, Bruckert E, Thibault V, Theodorou I, et al. Liver fibrosis in overweight patients. Gastroenterology 2000;118:1117-23.
-
(2000)
Gastroenterology
, vol.118
, pp. 1117-1123
-
-
Ratziu, V.1
Giral, P.2
Charlotte, F.3
Bruckert, E.4
Thibault, V.5
Theodorou, I.6
-
12
-
-
0032945299
-
Cause-specific mortality in type 2 diabetes. The Verona Diabetes Study
-
de Marco R, Locatelli F, Zoppini G, Verlato G, Bonora E, Muggeo M. Cause-specific mortality in type 2 diabetes. The Verona Diabetes Study. Diabetes Care 1999;22:756-61.
-
(1999)
Diabetes Care
, vol.22
, pp. 756-761
-
-
de Marco, R.1
Locatelli, F.2
Zoppini, G.3
Verlato, G.4
Bonora, E.5
Muggeo, M.6
-
13
-
-
0037566201
-
Clinical and histologic spectrum of nonalcoholic fatty liver disease associated with normal ALT values
-
Mofrad P, Contos MJ, Haque M, Sargeant C, Fisher RA, Luketic VA, et al. Clinical and histologic spectrum of nonalcoholic fatty liver disease associated with normal ALT values. Hepatology 2003;37:1286-92.
-
(2003)
Hepatology
, vol.37
, pp. 1286-1292
-
-
Mofrad, P.1
Contos, M.J.2
Haque, M.3
Sargeant, C.4
Fisher, R.A.5
Luketic, V.A.6
-
14
-
-
18244364864
-
NASH and insulin resistance: Insulin secretion and specific association with the insulin resistance syndrome
-
Chitturi S, Abeygunasekera S, Farrell GC, Holmes-Walker J, Hui J, Fung C, et al. NASH and insulin resistance: insulin secretion and specific association with the insulin resistance syndrome. Hepatology 2002;35:373-9.
-
(2002)
Hepatology
, vol.35
, pp. 373-379
-
-
Chitturi, S.1
Abeygunasekera, S.2
Farrell, G.C.3
Holmes-Walker, J.4
Hui, J.5
Fung, C.6
-
15
-
-
18244385511
-
Nonalcoholic steatohepatitis, insulin resistance, and metabolic syndrome: Further evidence for an etiologic association
-
Pagano G, Pacini G, Musso G, Gambino R, Mecca F, Depetris N, et al. Nonalcoholic steatohepatitis, insulin resistance, and metabolic syndrome: further evidence for an etiologic association. Hepatology 2002;35:367-72.
-
(2002)
Hepatology
, vol.35
, pp. 367-372
-
-
Pagano, G.1
Pacini, G.2
Musso, G.3
Gambino, R.4
Mecca, F.5
Depetris, N.6
-
16
-
-
0034978317
-
Insulin resistance in non-alcoholic steatohepatitis
-
Comert B, Mas MR, Erdem H, Dinc A, Saglamkaya U, Cigerim M, et al. Insulin resistance in non-alcoholic steatohepatitis. Dig Liver Dis 2001;33:353-8.
-
(2001)
Dig. Liver Dis.
, vol.33
, pp. 353-358
-
-
Comert, B.1
Mas, M.R.2
Erdem, H.3
Dinc, A.4
Saglamkaya, U.5
Cigerim, M.6
-
17
-
-
0035431018
-
Nonalcoholic fatty liver disease: A feature of the metabolic syndrome
-
Marchesini G, Brizi M, Bianchi G, Tomassetti S, Bugianesi E, Lenzi M, et al. Nonalcoholic fatty liver disease: a feature of the metabolic syndrome. Diabetes 2001;50:1844-50.
-
(2001)
Diabetes
, vol.50
, pp. 1844-1850
-
-
Marchesini, G.1
Brizi, M.2
Bianchi, G.3
Tomassetti, S.4
Bugianesi, E.5
Lenzi, M.6
-
18
-
-
0035084699
-
Nonalcoholic steatohepatitis: Association of insulin resistance and mitochondrial abnormalities
-
Sanyal AJ, Campbell-Sargent C, Mirshahi F, Rizzo WB, Contos MJ, Sterling RK, et al. Nonalcoholic steatohepatitis: association of insulin resistance and mitochondrial abnormalities. Gastroenterology 2001;120:1183-92.
-
(2001)
Gastroenterology
, vol.120
, pp. 1183-1192
-
-
Sanyal, A.J.1
Campbell-Sargent, C.2
Mirshahi, F.3
Rizzo, W.B.4
Contos, M.J.5
Sterling, R.K.6
-
19
-
-
0035120396
-
A pilot study of a thiazolidinedione, troglitazone, in nonalcoholic steatohepatitis
-
Caldwell SH, Hespenheide EE, Redick JA, Iezzoni JC, Battle EH, Sheppard BL. A pilot study of a thiazolidinedione, troglitazone, in nonalcoholic steatohepatitis. Am J Gastroenterol 2001;96:519-25.
-
(2001)
Am. J. Gastroenterol.
, vol.96
, pp. 519-525
-
-
Caldwell, S.H.1
Hespenheide, E.E.2
Redick, J.A.3
Iezzoni, J.C.4
Battle, E.H.5
Sheppard, B.L.6
-
20
-
-
0012785395
-
Metformin reverses fatty liver disease in obese, leptin-deficient mice
-
Lin HZ, Yang SQ, Chuckaree C, Kuhajda F, Ronnet G, Diehl AM. Metformin reverses fatty liver disease in obese, leptin-deficient mice. Nat Med 2000;6:998-1003.
-
(2000)
Nat. Med.
, vol.6
, pp. 998-1003
-
-
Lin, H.Z.1
Yang, S.Q.2
Chuckaree, C.3
Kuhajda, F.4
Ronnet, G.5
Diehl, A.M.6
-
21
-
-
0035883890
-
Metformin in non-alcoholic steatohepatitis
-
Marchesini G, Brizi M, Bianchi G, Tomassetti S, Zoli M, Melchionda N. Metformin in non-alcoholic steatohepatitis. Lancet 2001;358:893-4.
-
(2001)
Lancet
, vol.358
, pp. 893-894
-
-
Marchesini, G.1
Brizi, M.2
Bianchi, G.3
Tomassetti, S.4
Zoli, M.5
Melchionda, N.6
-
22
-
-
0037385387
-
Interim results of a pilot study demonstrating the early effects of the PPAR-gamma ligand rosiglitazone on insulin sensitivity, aminotransferases, hepatic steatosis and body weight in patients with non-alcoholic steatohepatitis
-
Neuschwander-Tetri BA, Brunt EM, Wehmeier KR, Sponseller CA, Hampton K, Bacon BR. Interim results of a pilot study demonstrating the early effects of the PPAR-gamma ligand rosiglitazone on insulin sensitivity, aminotransferases, hepatic steatosis and body weight in patients with non-alcoholic steatohepatitis. J Hepatol 2003;38:434-40.
-
(2003)
J. Hepatol.
, vol.38
, pp. 434-440
-
-
Neuschwander-Tetri, B.A.1
Brunt, E.M.2
Wehmeier, K.R.3
Sponseller, C.A.4
Hampton, K.5
Bacon, B.R.6
-
23
-
-
0141532275
-
Improved nonalcoholic steatohepatitis after 48 weeks of treatment with the PPAR-gamma ligand rosiglitazone
-
Neuschwander-Tetri BA, Brunt EM, Wehmeier KR, Oliver D, Bacon BR. Improved nonalcoholic steatohepatitis after 48 weeks of treatment with the PPAR-gamma ligand rosiglitazone. Hepatology 2003;38:1008-17.
-
(2003)
Hepatology
, vol.38
, pp. 1008-1017
-
-
Neuschwander-Tetri, B.A.1
Brunt, E.M.2
Wehmeier, K.R.3
Oliver, D.4
Bacon, B.R.5
-
24
-
-
0024160877
-
Banting lecture 1988. Role of insulin resistance in human diabetes
-
Reaven GM. Banting lecture 1988. Role of insulin resistance in human diabetes. Diabetes 1988;37:1595-607.
-
(1988)
Diabetes
, vol.37
, pp. 1595-1607
-
-
Reaven, G.M.1
-
25
-
-
0028961110
-
Diabetes and cardiovascular disease. The "common soil" hypothesis
-
Stern MP. Diabetes and cardiovascular disease. The "common soil" hypothesis. Diabetes 1995;44:369-74.
-
(1995)
Diabetes
, vol.44
, pp. 369-374
-
-
Stern, M.P.1
-
26
-
-
0029887286
-
Clustering of dyslipidemia, hyperuricemia, diabetes, and hypertension and its association with fasting insulin and central and overall obesity in a general population
-
Schmidt MI, Watson RL, Duncan BB, Metcalf P, Brancati FL, Sharrett AR, et al. Clustering of dyslipidemia, hyperuricemia, diabetes, and hypertension and its association with fasting insulin and central and overall obesity in a general population. Metabolism 1996;45:699-706.
-
(1996)
Metabolism
, vol.45
, pp. 699-706
-
-
Schmidt, M.I.1
Watson, R.L.2
Duncan, B.B.3
Metcalf, P.4
Brancati, F.L.5
Sharrett, A.R.6
-
27
-
-
0026762721
-
Prospective analysis of the insulin-resistance syndrome (syndrome X)
-
Haffner SM, Valdez RA, Hazuda HP, Mitchell BD, Morales PA, Stern MP. Prospective analysis of the insulin-resistance syndrome (syndrome X). Diabetes 1992;41:715-22.
-
(1992)
Diabetes
, vol.41
, pp. 715-722
-
-
Haffner, S.M.1
Valdez, R.A.2
Hazuda, H.P.3
Mitchell, B.D.4
Morales, P.A.5
Stern, M.P.6
-
28
-
-
0026021161
-
Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease
-
DeFronzo RA, Ferrannini E. Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease. Diabetes Care 1991;14:173-94.
-
(1991)
Diabetes Care
, vol.14
, pp. 173-194
-
-
DeFronzo, R.A.1
Ferrannini, E.2
-
29
-
-
0003725206
-
Definition, diagnosis and classification of diabetes mellitus and its complications
-
WHO Consultation. WHO/NCD/NCS/99.2. Geneva: World Health Organization
-
WHO Consultation. Definition, diagnosis and classification of diabetes mellitus and its complications. WHO/NCD/NCS/99.2. Geneva: World Health Organization; 1999.
-
(1999)
-
-
-
30
-
-
0032709705
-
Comment on the provisional report from the WHO consultation
-
for the European Group for the Study of Insulin Resistance (EGIR)
-
Balkau B, Charles MA, for the European Group for the Study of Insulin Resistance (EGIR). Comment on the provisional report from the WHO consultation. Diabet Med 1999;16:442-3.
-
(1999)
Diabet. Med.
, vol.16
, pp. 442-443
-
-
Balkau, B.1
Charles, M.A.2
-
31
-
-
0035897696
-
Executive summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
-
Expert Panel on Detection Evaluation and Treatment of High Blood Cholesterol in Adults
-
Expert Panel on Detection Evaluation and Treatment of High Blood Cholesterol in Adults. Executive summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). J Am Med Assoc 2001;285:2486-97.
-
(2001)
J. Am. Med. Assoc.
, vol.285
, pp. 2486-2497
-
-
-
32
-
-
0033005062
-
1999 World Health Organization-International Society of Hypertension guidelines for the management of hypertension
-
Guidelines Subcommittee
-
Guidelines Subcommittee. 1999 World Health Organization-International Society of Hypertension guidelines for the management of hypertension. J Hypertens 1999;17:151-83.
-
(1999)
J. Hypertens.
, vol.17
, pp. 151-183
-
-
-
33
-
-
0037382786
-
Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome
-
Marchesini G, Bugianesi E, Forlani G, Cerrelli F, Lenzi M, Manini R, et al. Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome. Hepatology 2003;37:917-23.
-
(2003)
Hepatology
, vol.37
, pp. 917-923
-
-
Marchesini, G.1
Bugianesi, E.2
Forlani, G.3
Cerrelli, F.4
Lenzi, M.5
Manini, R.6
-
34
-
-
0037631831
-
Insulin resistance and chronic cardiovascular inflammatory syndrome
-
Fernandez-Real JM, Ricart W. Insulin resistance and chronic cardiovascular inflammatory syndrome. Endocr Rev 2003;24:278-301.
-
(2003)
Endocr. Rev.
, vol.24
, pp. 278-301
-
-
Fernandez-Real, J.M.1
Ricart, W.2
-
35
-
-
0028931724
-
Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance
-
Hotamisligil GS, Arner P, Caro JF, Atkinson RL, Spiegelman BM. Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance. J Clin Invest 1995;95:2409-15.
-
(1995)
J. Clin. Invest.
, vol.95
, pp. 2409-2415
-
-
Hotamisligil, G.S.1
Arner, P.2
Caro, J.F.3
Atkinson, R.L.4
Spiegelman, B.M.5
-
36
-
-
0028968879
-
The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase
-
Kern PA, Saghizaheh M, Ong JM, Bosch RJ, Deem R, Simsolo RB. The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase. J Clin Invest 1995;95:2111-9.
-
(1995)
J. Clin. Invest.
, vol.95
, pp. 2111-2119
-
-
Kern, P.A.1
Saghizaheh, M.2
Ong, J.M.3
Bosch, R.J.4
Deem, R.5
Simsolo, R.B.6
-
37
-
-
0029952911
-
Leptin can induce proliferation, differentiation, and functional activation of hemopoietic cells
-
Gainsford T, Willson TA, Metcalf D, Handman E, McFarlane C, Ng A, et al. Leptin can induce proliferation, differentiation, and functional activation of hemopoietic cells. Proc Natl Acad Sci USA 1996;93:14564-8.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 14564-14568
-
-
Gainsford, T.1
Willson, T.A.2
Metcalf, D.3
Handman, E.4
McFarlane, C.5
Ng, A.6
-
38
-
-
0036240891
-
Leptin and liver fibrosis: A matter of fat
-
Marra F. Leptin and liver fibrosis: a matter of fat. Gastroenterology 2002;122:1529-32.
-
(2002)
Gastroenterology
, vol.122
, pp. 1529-1532
-
-
Marra, F.1
-
39
-
-
0036182137
-
Lipotoxic diseases
-
Unger RH. Lipotoxic diseases. Annu Rev Med 2002;53:319-36.
-
(2002)
Annu. Rev. Med.
, vol.53
, pp. 319-336
-
-
Unger, R.H.1
-
40
-
-
0031762908
-
Omental and subcutaneous adipose tissues of obese subjects release interleukin-6: Depot difference and regulation by glucocorticoid
-
Fried SK, Bunkin DA, Greenberg AS. Omental and subcutaneous adipose tissues of obese subjects release interleukin-6: depot difference and regulation by glucocorticoid. J Clin Endocrinol Metab 1998;83:847-50.
-
(1998)
J. Clin. Endocrinol. Metab.
, vol.83
, pp. 847-850
-
-
Fried, S.K.1
Bunkin, D.A.2
Greenberg, A.S.3
-
41
-
-
0035049305
-
Circulating interleukin 6 levels, blood pressure, and insulin sensitivity in apparently healthy men and women
-
Fernandez-Real JM, Vayreda M, Richart C, Gutierrez C, Broch M, Vendrell J, et al. Circulating interleukin 6 levels, blood pressure, and insulin sensitivity in apparently healthy men and women. J Clin Endocrinol Metab 2001;86:1154-9.
-
(2001)
J. Clin. Endocrinol. Metab.
, vol.86
, pp. 1154-1159
-
-
Fernandez-Real, J.M.1
Vayreda, M.2
Richart, C.3
Gutierrez, C.4
Broch, M.5
Vendrell, J.6
-
42
-
-
0036894360
-
Interleukin-6 induces cellular insulin resistance in hepatocytes
-
Senn JJ, Klover PJ, Nowak IA, Mooney RA. Interleukin-6 induces cellular insulin resistance in hepatocytes. Diabetes 2002;51:3391-9.
-
(2002)
Diabetes
, vol.51
, pp. 3391-3399
-
-
Senn, J.J.1
Klover, P.J.2
Nowak, I.A.3
Mooney, R.A.4
-
43
-
-
0030756346
-
Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function
-
Uysal KT, Wiesbrock SM, Marino MW, Hotamisligil GS. Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function. Nature 1997;389:610-4.
-
(1997)
Nature
, vol.389
, pp. 610-614
-
-
Uysal, K.T.1
Wiesbrock, S.M.2
Marino, M.W.3
Hotamisligil, G.S.4
-
44
-
-
0032577177
-
Leptin regulation of peroxisome proliferator-activated receptor-gamma, tumor necrosis factor, and uncoupling protein-2 expression in adipose tissues
-
Qian H, Hausman GJ, Compton MM, Azain MJ, Hartzell DL, Baile CA. Leptin regulation of peroxisome proliferator-activated receptor-gamma, tumor necrosis factor, and uncoupling protein-2 expression in adipose tissues. Biochem Biophys Res Commun 1998;246:660-7.
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.246
, pp. 660-667
-
-
Qian, H.1
Hausman, G.J.2
Compton, M.M.3
Azain, M.J.4
Hartzell, D.L.5
Baile, C.A.6
-
45
-
-
0041302377
-
The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice
-
Xu A, Wang Y, Keshaw H, Xu LY, Lam KS, Cooper GJ. The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice. J Clin Invest 2003;112:91-100.
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 91-100
-
-
Xu, A.1
Wang, Y.2
Keshaw, H.3
Xu, L.Y.4
Lam, K.S.5
Cooper, G.J.6
-
46
-
-
0037205414
-
Hydroxylation and glycosylation of the four conserved lysine residues in the collagenous domain of adiponectin. Potential role in the modulation of its insulin-sensitizing activity
-
Wang Y, Xu A, Knight C, Xu LY, Cooper GJ. Hydroxylation and glycosylation of the four conserved lysine residues in the collagenous domain of adiponectin. Potential role in the modulation of its insulin-sensitizing activity. J Biol Chem 2002;277:19521-9.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 19521-19529
-
-
Wang, Y.1
Xu, A.2
Knight, C.3
Xu, L.Y.4
Cooper, G.J.5
-
47
-
-
0028815235
-
Insulin and counterregulatory hormones influence acute-phase protein production in human hepatocytes
-
O'Riordain MG, Ross JA, Fearon KC, Maingay J, Farouk M, Garden OJ, et al. Insulin and counterregulatory hormones influence acute-phase protein production in human hepatocytes. Am J Physiol 1995;269:E323-30.
-
(1995)
Am. J. Physiol.
, vol.269
-
-
O'Riordain, M.G.1
Ross, J.A.2
Fearon, K.C.3
Maingay, J.4
Farouk, M.5
Garden, O.J.6
-
48
-
-
0024454923
-
Increased levels of acute-phase serum proteins in diabetes
-
McMillan DE. Increased levels of acute-phase serum proteins in diabetes. Metabolism 1989;38:1042-6.
-
(1989)
Metabolism
, vol.38
, pp. 1042-1046
-
-
McMillan, D.E.1
-
49
-
-
0033556440
-
Diabetes mellitus and serum carotenoids: Findings from the Third National Health and Nutrition Examination Survey
-
Ford ES, Will JC, Bowman BA, Narayan KM. Diabetes mellitus and serum carotenoids: findings from the Third National Health and Nutrition Examination Survey. Am J Epidemiol 1999;149:168-76.
-
(1999)
Am. J. Epidemiol.
, vol.149
, pp. 168-176
-
-
Ford, E.S.1
Will, J.C.2
Bowman, B.A.3
Narayan, K.M.4
-
50
-
-
12244280846
-
Insulin resistance and adiposity correlate with acute-phase reaction and soluble cell adhesion molecules in type 2 diabetes
-
Leinonen E, Hurt-Camejo E, Wiklund O, Hulten LM, Hiukka A, Taskinen MR. Insulin resistance and adiposity correlate with acute-phase reaction and soluble cell adhesion molecules in type 2 diabetes. Atherosclerosis 2003;166:387-94.
-
(2003)
Atherosclerosis
, vol.166
, pp. 387-394
-
-
Leinonen, E.1
Hurt-Camejo, E.2
Wiklund, O.3
Hulten, L.M.4
Hiukka, A.5
Taskinen, M.R.6
-
51
-
-
0033537013
-
Elevated C-reactive protein levels in overweight and obese adults
-
Visser M, Bouter LM, McQuillan GM, Wener MH, Harris TB. Elevated C-reactive protein levels in overweight and obese adults. J Am Med Assoc 1999;282:2131-5.
-
(1999)
J. Am. Med. Assoc.
, vol.282
, pp. 2131-2135
-
-
Visser, M.1
Bouter, L.M.2
McQuillan, G.M.3
Wener, M.H.4
Harris, T.B.5
-
52
-
-
18744424296
-
Relation between iron stores and non-insulin dependent diabetes in men: Case-control study
-
Salonen JT, Tuomainen TP, Nyyssonen K, Lakka HM, Punnonen K. Relation between iron stores and non-insulin dependent diabetes in men: case-control study. Br Med J 1998;317:727.
-
(1998)
Br. Med. J.
, vol.317
, pp. 727
-
-
Salonen, J.T.1
Tuomainen, T.P.2
Nyyssonen, K.3
Lakka, H.M.4
Punnonen, K.5
-
53
-
-
1442281989
-
Relative contribution of iron burden, HFE mutations and insulin resistance to fibrosis in nonalcoholic fatty liver
-
Bugianesi E, Manzini P, D'Antico S, Vanni E, Longo F, Leone N, et al. Relative contribution of iron burden, HFE mutations and insulin resistance to fibrosis in nonalcoholic fatty liver. Hepatology 2004;39:179-87.
-
(2004)
Hepatology
, vol.39
, pp. 179-187
-
-
Bugianesi, E.1
Manzini, P.2
D'Antico, S.3
Vanni, E.4
Longo, F.5
Leone, N.6
-
54
-
-
0034794965
-
Turning down insulin signaling
-
Birnbaum MJ. Turning down insulin signaling. J Clin Invest 2001;108:655-9.
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 655-659
-
-
Birnbaum, M.J.1
-
55
-
-
0030061922
-
IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance
-
Hotamisligil GS, Peraldi P, Budavari A, Ellis R, White MF, Spiegelman BM. IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance. Science 1996;271:665-8.
-
(1996)
Science
, vol.271
, pp. 665-668
-
-
Hotamisligil, G.S.1
Peraldi, P.2
Budavari, A.3
Ellis, R.4
White, M.F.5
Spiegelman, B.M.6
-
56
-
-
18144444592
-
Defective hepatic mitochondrial respiratory chain in patients with nonalcoholic steatohepatitis
-
Perez-Carreras M, Del Hoyo P, Martin MA, Rubio JC, Martin A, Castellano G, et al. Defective hepatic mitochondrial respiratory chain in patients with nonalcoholic steatohepatitis. Hepatology 2003;38:999-1007.
-
(2003)
Hepatology
, vol.38
, pp. 999-1007
-
-
Perez-Carreras, M.1
Del Hoyo, P.2
Martin, M.A.3
Rubio, J.C.4
Martin, A.5
Castellano, G.6
-
57
-
-
0031014830
-
Role of fatty acids in the pathogenesis of insulin resistance and NIDDM
-
Boden G. Role of fatty acids in the pathogenesis of insulin resistance and NIDDM. Diabetes 1997;46:3-10.
-
(1997)
Diabetes
, vol.46
, pp. 3-10
-
-
Boden, G.1
-
58
-
-
0345086474
-
Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade
-
Griffin ME, Marcucci MJ, Cline GW, Bell K, Barucci N, Lee D, et al. Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade. Diabetes 1999;48:1270-4.
-
(1999)
Diabetes
, vol.48
, pp. 1270-1274
-
-
Griffin, M.E.1
Marcucci, M.J.2
Cline, G.W.3
Bell, K.4
Barucci, N.5
Lee, D.6
-
59
-
-
0033996762
-
The I kappa B kinase (IKK) and NF-kappa B: Key elements of proinflammatory signalling
-
Karin M, Delhase M. The I kappa B kinase (IKK) and NF-kappa B: key elements of proinflammatory signalling. Semin Immunol 2000;12:85-98.
-
(2000)
Semin. Immunol.
, vol.12
, pp. 85-98
-
-
Karin, M.1
Delhase, M.2
-
60
-
-
0037836086
-
Insulin resistance, inflammation, and serum fatty acid composition
-
Fernandez-Real JM, Broch M, Vendrell J, Ricart W. Insulin resistance, inflammation, and serum fatty acid composition. Diabetes Care 2003;26:1362-8.
-
(2003)
Diabetes Care
, vol.26
, pp. 1362-1368
-
-
Fernandez-Real, J.M.1
Broch, M.2
Vendrell, J.3
Ricart, W.4
-
61
-
-
0024489402
-
The effect of dietary supplementation with n-3 polyunsaturated fatty acids on the synthesis of interleukin-1 and tumor necrosis factor by mononuclear cells
-
Endres S, Ghorbani R, Kelley VE, Georgilis K, Lonnemann G, van der Meer JW, et al. The effect of dietary supplementation with n-3 polyunsaturated fatty acids on the synthesis of interleukin-1 and tumor necrosis factor by mononuclear cells. N Engl J Med 1989;320:265-71.
-
(1989)
N. Engl. J. Med.
, vol.320
, pp. 265-271
-
-
Endres, S.1
Ghorbani, R.2
Kelley, V.E.3
Georgilis, K.4
Lonnemann, G.5
van der Meer, J.W.6
-
62
-
-
0037382071
-
Dietary habits and their relations to insulin resistance and postprandial lipemia in nonalcoholic steatohepatitis
-
Musso G, Gambino R, De Michieli F, Cassader M, Rizzetto M, Durazzo M, et al. Dietary habits and their relations to insulin resistance and postprandial lipemia in nonalcoholic steatohepatitis. Hepatology 2003;37:909-16.
-
(2003)
Hepatology
, vol.37
, pp. 909-916
-
-
Musso, G.1
Gambino, R.2
De Michieli, F.3
Cassader, M.4
Rizzetto, M.5
Durazzo, M.6
-
63
-
-
0034915177
-
Insulin inhibits intranuclear nuclear factor kappaB and stimulates IkappaB in mononuclear cells in obese subjects: Evidence for an anti-inflammatory effect?
-
Dandona P, Aljada A, Mohanty P, Ghanim H, Hamouda W, Assian E, et al. Insulin inhibits intranuclear nuclear factor kappaB and stimulates IkappaB in mononuclear cells in obese subjects: evidence for an anti-inflammatory effect? J Clin Endocrinol Metab 2001;86:3257-65.
-
(2001)
J. Clin. Endocrinol. Metab.
, vol.86
, pp. 3257-3265
-
-
Dandona, P.1
Aljada, A.2
Mohanty, P.3
Ghanim, H.4
Hamouda, W.5
Assian, E.6
-
64
-
-
0035045084
-
Suppression of nuclear factor-kappaB and stimulation of inhibitor kappaB by troglitazone: Evidence for an anti-inflammatory effect and a potential antiatherosclerotic effect in the obese
-
Ghanim H, Garg R, Aljada A, Mohanty P, Kumbkarni Y, Assian E, et al. Suppression of nuclear factor-kappaB and stimulation of inhibitor kappaB by troglitazone: evidence for an anti-inflammatory effect and a potential antiatherosclerotic effect in the obese. J Clin Endocrinol Metab 2001;86:1306-12.
-
(2001)
J. Clin. Endocrinol. Metab.
, vol.86
, pp. 1306-1312
-
-
Ghanim, H.1
Garg, R.2
Aljada, A.3
Mohanty, P.4
Kumbkarni, Y.5
Assian, E.6
-
65
-
-
0036842574
-
Antiinflammatory and antiarteriosclerotic effects of pioglitazone
-
Ishibashi M, Egashira K, Hiasa K, Inoue S, Ni W, Zhao Q, et al. Antiinflammatory and antiarteriosclerotic effects of pioglitazone. Hypertension 2002;40:687-93.
-
(2002)
Hypertension
, vol.40
, pp. 687-693
-
-
Ishibashi, M.1
Egashira, K.2
Hiasa, K.3
Inoue, S.4
Ni, W.5
Zhao, Q.6
-
66
-
-
0036597085
-
The anti-inflammatory and potential anti-atherogenic effect of insulin: A new paradigm
-
Dandona P, Aljada A, Mohanty P. The anti-inflammatory and potential anti-atherogenic effect of insulin: a new paradigm. Diabetologia 2002;45:924-30.
-
(2002)
Diabetologia
, vol.45
, pp. 924-930
-
-
Dandona, P.1
Aljada, A.2
Mohanty, P.3
-
67
-
-
0037010478
-
Role of peroxisome proliferator-activated receptor gamma and retinoid X receptor heterodimer in hepatogastroenterological diseases
-
Dubuquoy L, Dharancy S, Nutten S, Pettersson S, Auwerx J, Desreumaux P. Role of peroxisome proliferator-activated receptor gamma and retinoid X receptor heterodimer in hepatogastroenterological diseases. Lancet 2002;360:1410-8.
-
(2002)
Lancet
, vol.360
, pp. 1410-1418
-
-
Dubuquoy, L.1
Dharancy, S.2
Nutten, S.3
Pettersson, S.4
Auwerx, J.5
Desreumaux, P.6
-
68
-
-
0036086754
-
Pioglitazone prevents early-phase hepatic fibrogenesis caused by carbon tetrachloride
-
Kon K, Ikejima K, Hirose M, Yoshikawa M, Enomoto N, Kitamura T, et al. Pioglitazone prevents early-phase hepatic fibrogenesis caused by carbon tetrachloride. Biochem Biophys Res Commun 2002;291: 55-61.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.291
, pp. 55-61
-
-
Kon, K.1
Ikejima, K.2
Hirose, M.3
Yoshikawa, M.4
Enomoto, N.5
Kitamura, T.6
-
69
-
-
0033855572
-
Ligands of peroxisome proliferator-activated receptor gamma modulate profibrogenic and proinflammatory actions in hepatic stellate cells
-
Marra F, Efsen E, Romanelli RG, Caligiuri A, Pastacaldi S, Batignani G, et al. Ligands of peroxisome proliferator-activated receptor gamma modulate profibrogenic and proinflammatory actions in hepatic stellate cells. Gastroenterology 2000;119:466-78.
-
(2000)
Gastroenterology
, vol.119
, pp. 466-478
-
-
Marra, F.1
Efsen, E.2
Romanelli, R.G.3
Caligiuri, A.4
Pastacaldi, S.5
Batignani, G.6
-
70
-
-
0042165989
-
Hepatocyte apoptosis and fas expression are prominent features of human nonalcoholic steatohepatitis
-
Feldstein AE, Canbay A, Angulo P, Taniai M, Burgart LJ, Lindor KD, et al. Hepatocyte apoptosis and fas expression are prominent features of human nonalcoholic steatohepatitis. Gastroenterology 2003;125:437-43.
-
(2003)
Gastroenterology
, vol.125
, pp. 437-443
-
-
Feldstein, A.E.1
Canbay, A.2
Angulo, P.3
Taniai, M.4
Burgart, L.J.5
Lindor, K.D.6
-
71
-
-
0030943158
-
Hyperleptinaemia: The missing link in the metabolic syndrome?
-
de Courten M, Zimmet P, Hodge A, Collins V, Nicolson M, Staten M, et al. Hyperleptinaemia: the missing link in the metabolic syndrome? Diabet Med 1997;14:200-8.
-
(1997)
Diabet. Med.
, vol.14
, pp. 200-208
-
-
de Courten, M.1
Zimmet, P.2
Hodge, A.3
Collins, V.4
Nicolson, M.5
Staten, M.6
-
72
-
-
0033811210
-
Leptin plasma concentrations are dependent on body fat distribution in obese patients
-
Minocci A, Savia G, Lucantoni R, Berselli ME, Tagliaferri M, Calo G, et al. Leptin plasma concentrations are dependent on body fat distribution in obese patients. Int J Obes Relat Metab Disord 2000;24:1139-44.
-
(2000)
Int. J. Obes. Relat. Metab. Disord.
, vol.24
, pp. 1139-1144
-
-
Minocci, A.1
Savia, G.2
Lucantoni, R.3
Berselli, M.E.4
Tagliaferri, M.5
Calo, G.6
-
73
-
-
0034668796
-
Gene polymorphisms in the TNF locus and the risk of myocardial infarction
-
Padovani JC, Pazin-Filho A, Simoes MV, Marin-Neto JA, Zago MA, Franco RF. Gene polymorphisms in the TNF locus and the risk of myocardial infarction. Thromb Res 2000;100:263-9.
-
(2000)
Thromb. Res.
, vol.100
, pp. 263-269
-
-
Padovani, J.C.1
Pazin-Filho, A.2
Simoes, M.V.3
Marin-Neto, J.A.4
Zago, M.A.5
Franco, R.F.6
-
74
-
-
0034053908
-
Excessive fat accumulation is associated with the TNF alpha-308 G/A promoter polymorphism in women but not in men
-
Hoffstedt J, Eriksson P, Hellstrom L, Rossner S, Ryden M, Arner P. Excessive fat accumulation is associated with the TNF alpha-308 G/A promoter polymorphism in women but not in men. Diabetologia 2000;43:117-20.
-
(2000)
Diabetologia
, vol.43
, pp. 117-120
-
-
Hoffstedt, J.1
Eriksson, P.2
Hellstrom, L.3
Rossner, S.4
Ryden, M.5
Arner, P.6
-
75
-
-
0036389428
-
Pro12Ala substitution in the peroxisome proliferator-activated receptor-gamma is associated with increased leptin levels in women with type-2 diabetes mellitus
-
Simon I, Vendrell J, Gutierrez C, Fernandez-Real JM, Vendrell I, Gallart L, et al. Pro12Ala substitution in the peroxisome proliferator-activated receptor-gamma is associated with increased leptin levels in women with type-2 diabetes mellitus. Horm Res 2002;58:143-9.
-
(2002)
Horm. Res.
, vol.58
, pp. 143-149
-
-
Simon, I.1
Vendrell, J.2
Gutierrez, C.3
Fernandez-Real, J.M.4
Vendrell, I.5
Gallart, L.6
-
76
-
-
0033594980
-
A critical role for the peroxisome proliferator-activated receptor alpha (PPARalpha) in the cellular fasting response: The PPARalpha-null mouse as a model of fatty acid oxidation disorders
-
Leone TC, Weinheimer CJ, Kelly DP. A critical role for the peroxisome proliferator-activated receptor alpha (PPARalpha) in the cellular fasting response: the PPARalpha-null mouse as a model of fatty acid oxidation disorders. Proc Natl Acad Sci USA 1999;96: 7473-8.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 7473-7478
-
-
Leone, T.C.1
Weinheimer, C.J.2
Kelly, D.P.3
-
77
-
-
0030716183
-
Antibodies to tumor necrosis factor alfa attenuate hepatic necrosis and inflammation caused by chronic exposure to ethanol in the rat
-
Iimuro Y, Gallucci RM, Luster MI, Kono H, Thurman RG. Antibodies to tumor necrosis factor alfa attenuate hepatic necrosis and inflammation caused by chronic exposure to ethanol in the rat. Hepatology 1997;26:1530-7.
-
(1997)
Hepatology
, vol.26
, pp. 1530-1537
-
-
Iimuro, Y.1
Gallucci, R.M.2
Luster, M.I.3
Kono, H.4
Thurman, R.G.5
-
78
-
-
0030955323
-
Choline deficiency augments and antibody to tumor necrosis factor-alpha attenuates endotoxin-induced hepatic injury
-
Eastin CE, McClain CJ, Lee EY, Bagby GJ, Chawla RK. Choline deficiency augments and antibody to tumor necrosis factor-alpha attenuates endotoxin-induced hepatic injury. Alcohol Clin Exp Res 1997;21:1037-41.
-
(1997)
Alcohol Clin. Exp. Res.
, vol.21
, pp. 1037-1041
-
-
Eastin, C.E.1
McClain, C.J.2
Lee, E.Y.3
Bagby, G.J.4
Chawla, R.K.5
-
79
-
-
0037840403
-
Effect of weight loss and lifestyle changes on vascular inflammatory markers in obese women: A randomized trial
-
Esposito K, Pontillo A, Di Palo C, Giugliano G, Masella M, Marfella R, et al. Effect of weight loss and lifestyle changes on vascular inflammatory markers in obese women: a randomized trial. J Am Med Assoc 2003;289:1799-804.
-
(2003)
J. Am. Med. Assoc.
, vol.289
, pp. 1799-1804
-
-
Esposito, K.1
Pontillo, A.2
Di Palo, C.3
Giugliano, G.4
Masella, M.5
Marfella, R.6
-
80
-
-
0033549059
-
Long-term exercise and atherogenic activity of blood mononuclear cells in persons at risk of developing ischemic heart disease
-
Smith JK, Dykes R, Douglas JE, Krishnaswamy G, Berk S. Long-term exercise and atherogenic activity of blood mononuclear cells in persons at risk of developing ischemic heart disease. J Am Med Assoc 1999;281:1722-7.
-
(1999)
J. Am. Med. Assoc.
, vol.281
, pp. 1722-1727
-
-
Smith, J.K.1
Dykes, R.2
Douglas, J.E.3
Krishnaswamy, G.4
Berk, S.5
-
81
-
-
0242268980
-
Type 2 diabetes and the Naaman syndrome
-
Marchesini G, Trovati M. Type 2 diabetes and the Naaman syndrome. Diabetes Care 2003;26:3195.
-
(2003)
Diabetes Care
, vol.26
, pp. 3195
-
-
Marchesini, G.1
Trovati, M.2
|