P2X7 receptor-NADPH oxidase axis mediates protein radical formation and Kupffer cell activation in carbon tetrachloride-mediated steatohepatitis in obese mice

Free Radical Biology and Medicine

Volumn 52, Issue 9, 2012, Pages 1666-1679

  Chatterjee, Saurabh ^a   Rana, Ritu ^a   Corbett, Jean ^a   Kadiiska, Maria B ^a   Goldstein, Joyce ^a   Mason, Ronald P ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Antigen presentation; Damage Associated Molecular Pattern; Kupffer cell; NADPH oxidase steatohepatitis; Protein radical

Indexed keywords

ADENOSINE TRIPHOSPHATE; APOCYNIN; CARBON TETRACHLORIDE; FREE RADICAL; MONOCYTE CHEMOTACTIC PROTEIN 2; PROTEIN P47; PURINERGIC P2X7 RECEPTOR; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; EXTRACELLULAR SPACE; GENE SILENCING; KUPFFER CELL; LIVER CELL; MALE; MOUSE; NONALCOHOLIC FATTY LIVER; NONHUMAN; OBESITY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN SYNTHESIS;

ANIMALS; CARBON TETRACHLORIDE; COCULTURE TECHNIQUES; FATTY LIVER; KUPFFER CELLS; MALE; MICE; MICE, INBRED C57BL; MICROSCOPY, CONFOCAL; NADPH OXIDASE; OBESITY; OXIDATIVE STRESS; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, PURINERGIC P2X7;

MUS;

EID: 84858968917     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2012.02.010     Document Type: Article

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