메뉴 건너뛰기




Volumn 8, Issue 7, 2013, Pages

Dual Regulatory Roles of Human AP-Endonuclease (APE1/Ref-1) in CDKN1A/p21 Expression

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1A; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; PROTEIN P21; PROTEIN P53;

EID: 84880486045     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0068467     Document Type: Article
Times cited : (20)

References (69)
  • 2
    • 0025120572 scopus 로고
    • The enzymology of apurinic/apyrimidinic endonucleases
    • Doetsch PW, Cunningham RP, (1990) The enzymology of apurinic/apyrimidinic endonucleases. Mutat Res 236: 173-201.
    • (1990) Mutat Res , vol.236 , pp. 173-201
    • Doetsch, P.W.1    Cunningham, R.P.2
  • 3
    • 0242268065 scopus 로고    scopus 로고
    • Mammalian DNA base excision repair proteins: their interactions and role in repair of oxidative DNA damage
    • Izumi T, Wiederhold LR, Roy G, Roy R, Jaiswal A, et al. (2003) Mammalian DNA base excision repair proteins: their interactions and role in repair of oxidative DNA damage. Toxicology 193: 43-65.
    • (2003) Toxicology , vol.193 , pp. 43-65
    • Izumi, T.1    Wiederhold, L.R.2    Roy, G.3    Roy, R.4    Jaiswal, A.5
  • 4
    • 33845755016 scopus 로고    scopus 로고
    • Major oxidative products of cytosine are substrates for the nucleotide incision repair pathway
    • Daviet S, Couve-Privat S, Gros L, Shinozuka K, Ide H, et al. (2007) Major oxidative products of cytosine are substrates for the nucleotide incision repair pathway. DNA repair 6: 8-18.
    • (2007) DNA Repair , vol.6 , pp. 8-18
    • Daviet, S.1    Couve-Privat, S.2    Gros, L.3    Shinozuka, K.4    Ide, H.5
  • 5
    • 1242320312 scopus 로고    scopus 로고
    • The major human AP endonuclease (Ape1) is involved in the nucleotide incision repair pathway
    • Gros L, Ishchenko AA, Ide H, Elder RH, Saparbaev MK, (2004) The major human AP endonuclease (Ape1) is involved in the nucleotide incision repair pathway. Nucleic acids research 32: 73-81.
    • (2004) Nucleic Acids Research , vol.32 , pp. 73-81
    • Gros, L.1    Ishchenko, A.A.2    Ide, H.3    Elder, R.H.4    Saparbaev, M.K.5
  • 7
    • 58849117092 scopus 로고    scopus 로고
    • Transcriptional regulatory functions of mammalian AP-endonuclease (APE1/Ref-1), an essential multifunctional protein
    • Bhakat KK, Mantha AK, Mitra S, (2009) Transcriptional regulatory functions of mammalian AP-endonuclease (APE1/Ref-1), an essential multifunctional protein. Antioxidants & redox signaling 11: 621-638.
    • (2009) Antioxidants & Redox Signaling , vol.11 , pp. 621-638
    • Bhakat, K.K.1    Mantha, A.K.2    Mitra, S.3
  • 10
    • 0027985675 scopus 로고
    • A redox factor protein, ref1, is involved in negative gene regulation by extracellular calcium
    • Okazaki T, Chung U, Nishishita T, Ebisu S, Usuda S, et al. (1994) A redox factor protein, ref1, is involved in negative gene regulation by extracellular calcium. J Biol Chem 269: 27855-27862.
    • (1994) J Biol Chem , vol.269 , pp. 27855-27862
    • Okazaki, T.1    Chung, U.2    Nishishita, T.3    Ebisu, S.4    Usuda, S.5
  • 11
    • 0037331196 scopus 로고    scopus 로고
    • Implication of Ref-1 in the repression of renin gene transcription by intracellular calcium
    • Fuchs S, Philippe J, Corvol P, Pinet F, (2003) Implication of Ref-1 in the repression of renin gene transcription by intracellular calcium. J Hypertens 21: 327-335.
    • (2003) J Hypertens , vol.21 , pp. 327-335
    • Fuchs, S.1    Philippe, J.2    Corvol, P.3    Pinet, F.4
  • 12
    • 84859882113 scopus 로고    scopus 로고
    • Regulation of mouse-renin gene by apurinic/apyrimidinic-endonuclease 1 (APE1/Ref-1) via recruitment of histone deacetylase 1 corepressor complex
    • Sengupta S, Chattopadhyay R, Mantha AK, Mitra S, Bhakat KK, (2012) Regulation of mouse-renin gene by apurinic/apyrimidinic-endonuclease 1 (APE1/Ref-1) via recruitment of histone deacetylase 1 corepressor complex. Journal of hypertension 30: 917-925.
    • (2012) Journal of Hypertension , vol.30 , pp. 917-925
    • Sengupta, S.1    Chattopadhyay, R.2    Mantha, A.K.3    Mitra, S.4    Bhakat, K.K.5
  • 13
    • 0347504848 scopus 로고    scopus 로고
    • Role of acetylated human AP-endonuclease (APE1/Ref-1) in regulation of the parathyroid hormone gene
    • Bhakat KK, Izumi T, Yang SH, Hazra TK, Mitra S, (2003) Role of acetylated human AP-endonuclease (APE1/Ref-1) in regulation of the parathyroid hormone gene. Embo J 22: 6299-6309.
    • (2003) Embo J , vol.22 , pp. 6299-6309
    • Bhakat, K.K.1    Izumi, T.2    Yang, S.H.3    Hazra, T.K.4    Mitra, S.5
  • 15
    • 66149107948 scopus 로고    scopus 로고
    • Acetylation of apurinic/apyrimidinic endonuclease-1 regulates Helicobacter pylori-mediated gastric epithelial cell apoptosis
    • Bhattacharyya A, Chattopadhyay R, Burnette BR, Cross JV, Mitra S, et al. (2009) Acetylation of apurinic/apyrimidinic endonuclease-1 regulates Helicobacter pylori-mediated gastric epithelial cell apoptosis. Gastroenterology 136: 2258-2269.
    • (2009) Gastroenterology , vol.136 , pp. 2258-2269
    • Bhattacharyya, A.1    Chattopadhyay, R.2    Burnette, B.R.3    Cross, J.V.4    Mitra, S.5
  • 17
    • 75149123984 scopus 로고    scopus 로고
    • Regulation of signal transducer and activator of transcription 3 enhanceosome formation by apurinic/apyrimidinic endonuclease 1 in hepatic acute phase response
    • Ray S, Lee C, Hou T, Bhakat KK, Brasier AR, (2010) Regulation of signal transducer and activator of transcription 3 enhanceosome formation by apurinic/apyrimidinic endonuclease 1 in hepatic acute phase response. Mol Endocrinol 24: 391-401.
    • (2010) Mol Endocrinol , vol.24 , pp. 391-401
    • Ray, S.1    Lee, C.2    Hou, T.3    Bhakat, K.K.4    Brasier, A.R.5
  • 18
    • 0029829265 scopus 로고    scopus 로고
    • The redox/DNA repair protein, Ref-1, is essential for early embryonic development in mice
    • Xanthoudakis S, Smeyne RJ, Wallace JD, Curran T, (1996) The redox/DNA repair protein, Ref-1, is essential for early embryonic development in mice. Proc Natl Acad Sci U S A 93: 8919-8923.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 8919-8923
    • Xanthoudakis, S.1    Smeyne, R.J.2    Wallace, J.D.3    Curran, T.4
  • 19
    • 0035879043 scopus 로고    scopus 로고
    • Heterozygosity for the mouse Apex gene results in phenotypes associated with oxidative stress
    • Meira LB, Devaraj S, Kisby GE, Burns DK, Daniel RL, et al. (2001) Heterozygosity for the mouse Apex gene results in phenotypes associated with oxidative stress. Cancer Res 61: 5552-5557.
    • (2001) Cancer Res , vol.61 , pp. 5552-5557
    • Meira, L.B.1    Devaraj, S.2    Kisby, G.E.3    Burns, D.K.4    Daniel, R.L.5
  • 21
    • 64049110265 scopus 로고    scopus 로고
    • Ubiquitination of mammalian AP endonuclease (APE1) regulated by the p53-MDM2 signaling pathway
    • Busso CS, Iwakuma T, Izumi T, (2009) Ubiquitination of mammalian AP endonuclease (APE1) regulated by the p53-MDM2 signaling pathway. Oncogene 28: 1616-1625.
    • (2009) Oncogene , vol.28 , pp. 1616-1625
    • Busso, C.S.1    Iwakuma, T.2    Izumi, T.3
  • 22
    • 77953121792 scopus 로고    scopus 로고
    • The role of Cdk5-mediated apurinic/apyrimidinic endonuclease 1 phosphorylation in neuronal death
    • Huang E, Qu D, Zhang Y, Venderova K, Haque ME, et al. (2010) The role of Cdk5-mediated apurinic/apyrimidinic endonuclease 1 phosphorylation in neuronal death. Nature cell biology 12: 563-571.
    • (2010) Nature Cell Biology , vol.12 , pp. 563-571
    • Huang, E.1    Qu, D.2    Zhang, Y.3    Venderova, K.4    Haque, M.E.5
  • 23
    • 80054083892 scopus 로고    scopus 로고
    • Ubiquitination of human AP-endonuclease 1 (APE1) enhanced by T233E substitution and by CDK5
    • Busso CS, Wedgeworth CM, Izumi T, (2011) Ubiquitination of human AP-endonuclease 1 (APE1) enhanced by T233E substitution and by CDK5. Nucleic acids research 39: 8017-8028.
    • (2011) Nucleic Acids Research , vol.39 , pp. 8017-8028
    • Busso, C.S.1    Wedgeworth, C.M.2    Izumi, T.3
  • 24
    • 0034905642 scopus 로고    scopus 로고
    • Elevated and altered expression of the multifunctional DNA base excision repair and redox enzyme Ape1/ref-1 in prostate cancer
    • Kelley MR, Cheng L, Foster R, Tritt R, Jiang J, et al. (2001) Elevated and altered expression of the multifunctional DNA base excision repair and redox enzyme Ape1/ref-1 in prostate cancer. Clin Cancer Res 7: 824-830.
    • (2001) Clin Cancer Res , vol.7 , pp. 824-830
    • Kelley, M.R.1    Cheng, L.2    Foster, R.3    Tritt, R.4    Jiang, J.5
  • 25
    • 0035266131 scopus 로고    scopus 로고
    • Altered expression of Ape1/ref-1 in germ cell tumors and overexpression in NT2 cells confers resistance to bleomycin and radiation
    • Robertson KA, Bullock HA, Xu Y, Tritt R, Zimmerman E, et al. (2001) Altered expression of Ape1/ref-1 in germ cell tumors and overexpression in NT2 cells confers resistance to bleomycin and radiation. Cancer Res 61: 2220-2225.
    • (2001) Cancer Res , vol.61 , pp. 2220-2225
    • Robertson, K.A.1    Bullock, H.A.2    Xu, Y.3    Tritt, R.4    Zimmerman, E.5
  • 26
    • 0031439376 scopus 로고    scopus 로고
    • The apurinic/apyrimidinic endonuclease (APE/ref-1) DNA repair enzyme is elevated in premalignant and malignant cervical cancer
    • Xu Y, Moore DH, Broshears J, Liu L, Wilson TM, et al. (1997) The apurinic/apyrimidinic endonuclease (APE/ref-1) DNA repair enzyme is elevated in premalignant and malignant cervical cancer. Anticancer Res 17: 3713-3719.
    • (1997) Anticancer Res , vol.17 , pp. 3713-3719
    • Xu, Y.1    Moore, D.H.2    Broshears, J.3    Liu, L.4    Wilson, T.M.5
  • 27
    • 57349170258 scopus 로고    scopus 로고
    • Regulatory role of human AP-endonuclease (APE1/Ref-1) in YB-1-mediated activation of the multidrug resistance gene MDR1
    • Chattopadhyay R, Das S, Maiti AK, Boldogh I, Xie J, et al. (2008) Regulatory role of human AP-endonuclease (APE1/Ref-1) in YB-1-mediated activation of the multidrug resistance gene MDR1. Mol Cell Biol 28: 7066-7080.
    • (2008) Mol Cell Biol , vol.28 , pp. 7066-7080
    • Chattopadhyay, R.1    Das, S.2    Maiti, A.K.3    Boldogh, I.4    Xie, J.5
  • 28
    • 34548276529 scopus 로고    scopus 로고
    • The DNA base excision repair protein Ape1/Ref-1 as a therapeutic and chemopreventive target
    • Fishel ML, Kelley MR, (2007) The DNA base excision repair protein Ape1/Ref-1 as a therapeutic and chemopreventive target. Mol Aspects Med 28: 375-395.
    • (2007) Mol Aspects Med , vol.28 , pp. 375-395
    • Fishel, M.L.1    Kelley, M.R.2
  • 29
    • 70349991252 scopus 로고    scopus 로고
    • Role of APE1 in differentiated neuroblastoma SH-SY5Y cells in response to oxidative stress: use of APE1 small molecule inhibitors to delineate APE1 functions
    • Jiang Y, Guo C, Fishel ML, Wang ZY, Vasko MR, et al. (2009) Role of APE1 in differentiated neuroblastoma SH-SY5Y cells in response to oxidative stress: use of APE1 small molecule inhibitors to delineate APE1 functions. DNA Repair (Amst) 8: 1273-1282.
    • (2009) DNA Repair (Amst) , vol.8 , pp. 1273-1282
    • Jiang, Y.1    Guo, C.2    Fishel, M.L.3    Wang, Z.Y.4    Vasko, M.R.5
  • 30
    • 51049100621 scopus 로고    scopus 로고
    • Implications of apurinic/apyrimidinic endonuclease in reactive oxygen signaling response after cisplatin treatment of dorsal root ganglion neurons
    • Jiang Y, Guo C, Vasko MR, Kelley MR, (2008) Implications of apurinic/apyrimidinic endonuclease in reactive oxygen signaling response after cisplatin treatment of dorsal root ganglion neurons. Cancer Res 68: 6425-6434.
    • (2008) Cancer Res , vol.68 , pp. 6425-6434
    • Jiang, Y.1    Guo, C.2    Vasko, M.R.3    Kelley, M.R.4
  • 31
    • 67649580307 scopus 로고    scopus 로고
    • Impairment of APE1 function enhances cellular sensitivity to clinically relevant alkylators and antimetabolites
    • McNeill DR, Lam W, DeWeese TL, Cheng YC, Wilson DM 3rd (2009) Impairment of APE1 function enhances cellular sensitivity to clinically relevant alkylators and antimetabolites. Mol Cancer Res 7: 897-906.
    • (2009) Mol Cancer Res , vol.7 , pp. 897-906
    • McNeill, D.R.1    Lam, W.2    DeWeese, T.L.3    Cheng, Y.C.4    Wilson 3rd, D.M.5
  • 32
    • 0030954254 scopus 로고    scopus 로고
    • Down-regulation of apurinic/apyrimidinic endonuclease expression is associated with the induction of apoptosis in differentiating myeloid leukemia cells
    • Robertson KA, Hill DP, Xu Y, Liu L, Van Epps S, et al. (1997) Down-regulation of apurinic/apyrimidinic endonuclease expression is associated with the induction of apoptosis in differentiating myeloid leukemia cells. Cell Growth Differ 8: 443-449.
    • (1997) Cell Growth Differ , vol.8 , pp. 443-449
    • Robertson, K.A.1    Hill, D.P.2    Xu, Y.3    Liu, L.4    Van Epps, S.5
  • 33
    • 4444327784 scopus 로고    scopus 로고
    • Human apurinic endonuclease 1 (APE1) expression and prognostic significance in osteosarcoma: enhanced sensitivity of osteosarcoma to DNA damaging agents using silencing RNA APE1 expression inhibition
    • Wang D, Luo M, Kelley MR, (2004) Human apurinic endonuclease 1 (APE1) expression and prognostic significance in osteosarcoma: enhanced sensitivity of osteosarcoma to DNA damaging agents using silencing RNA APE1 expression inhibition. Mol Cancer Ther 3: 679-686.
    • (2004) Mol Cancer Ther , vol.3 , pp. 679-686
    • Wang, D.1    Luo, M.2    Kelley, M.R.3
  • 34
    • 79251647522 scopus 로고    scopus 로고
    • Human AP endonuclease (APE1/Ref-1) and its acetylation regulate YB-1-p300 recruitment and RNA polymerase II loading in the drug-induced activation of multidrug resistance gene MDR1
    • Sengupta S, Mantha AK, Mitra S, Bhakat KK, (2011) Human AP endonuclease (APE1/Ref-1) and its acetylation regulate YB-1-p300 recruitment and RNA polymerase II loading in the drug-induced activation of multidrug resistance gene MDR1. Oncogene 30: 482-493.
    • (2011) Oncogene , vol.30 , pp. 482-493
    • Sengupta, S.1    Mantha, A.K.2    Mitra, S.3    Bhakat, K.K.4
  • 35
    • 70349438994 scopus 로고    scopus 로고
    • Tumour suppression by p53: a role for the DNA damage response?
    • Meek DW, (2009) Tumour suppression by p53: a role for the DNA damage response? Nature reviews Cancer 9: 714-723.
    • (2009) Nature Reviews Cancer , vol.9 , pp. 714-723
    • Meek, D.W.1
  • 37
    • 67649424560 scopus 로고    scopus 로고
    • p21 in cancer: intricate networks and multiple activities
    • Abbas T, Dutta A, (2009) p21 in cancer: intricate networks and multiple activities. Nat Rev Cancer 9: 400-414.
    • (2009) Nat Rev Cancer , vol.9 , pp. 400-414
    • Abbas, T.1    Dutta, A.2
  • 39
    • 0032553485 scopus 로고    scopus 로고
    • Requirement for p53 and p21 to sustain G2 arrest after DNA damage
    • Bunz F, Dutriaux A, Lengauer C, Waldman T, Zhou S, et al. (1998) Requirement for p53 and p21 to sustain G2 arrest after DNA damage. Science 282: 1497-1501.
    • (1998) Science , vol.282 , pp. 1497-1501
    • Bunz, F.1    Dutriaux, A.2    Lengauer, C.3    Waldman, T.4    Zhou, S.5
  • 40
    • 0030900605 scopus 로고    scopus 로고
    • Identification of redox/repair protein Ref-1 as a potent activator of p53
    • Jayaraman L, Murthy KG, Zhu C, Curran T, Xanthoudakis S, et al. (1997) Identification of redox/repair protein Ref-1 as a potent activator of p53. Genes Dev 11: 558-570.
    • (1997) Genes Dev , vol.11 , pp. 558-570
    • Jayaraman, L.1    Murthy, K.G.2    Zhu, C.3    Curran, T.4    Xanthoudakis, S.5
  • 41
    • 0033570048 scopus 로고    scopus 로고
    • Ref-1 regulates the transactivation and pro-apoptotic functions of p53 in vivo
    • Gaiddon C, Moorthy NC, Prives C, (1999) Ref-1 regulates the transactivation and pro-apoptotic functions of p53 in vivo. Embo J 18: 5609-5621.
    • (1999) Embo J , vol.18 , pp. 5609-5621
    • Gaiddon, C.1    Moorthy, N.C.2    Prives, C.3
  • 42
    • 61549109882 scopus 로고    scopus 로고
    • Genome-wide analysis and proteomic studies reveal APE1/Ref-1 multifunctional role in mammalian cells
    • Vascotto C, Cesaratto L, Zeef LA, Deganuto M, D'Ambrosio C, et al. (2009) Genome-wide analysis and proteomic studies reveal APE1/Ref-1 multifunctional role in mammalian cells. Proteomics 9: 1058-1074.
    • (2009) Proteomics , vol.9 , pp. 1058-1074
    • Vascotto, C.1    Cesaratto, L.2    Zeef, L.A.3    Deganuto, M.4    D'Ambrosio, C.5
  • 43
    • 77958001097 scopus 로고    scopus 로고
    • Reduced expression of DNA repair and redox signaling protein APE1/Ref-1 impairs human pancreatic cancer cell survival, proliferation, and cell cycle progression
    • Jiang Y, Zhou S, Sandusky GE, Kelley MR, Fishel ML, (2010) Reduced expression of DNA repair and redox signaling protein APE1/Ref-1 impairs human pancreatic cancer cell survival, proliferation, and cell cycle progression. Cancer investigation 28: 885-895.
    • (2010) Cancer Investigation , vol.28 , pp. 885-895
    • Jiang, Y.1    Zhou, S.2    Sandusky, G.E.3    Kelley, M.R.4    Fishel, M.L.5
  • 44
    • 3042674067 scopus 로고    scopus 로고
    • Acetylation of the human DNA glycosylase NEIL2 and inhibition of its activity
    • Bhakat KK, Hazra TK, Mitra S, (2004) Acetylation of the human DNA glycosylase NEIL2 and inhibition of its activity. Nucleic Acids Res 32: 3033-3039.
    • (2004) Nucleic Acids Res , vol.32 , pp. 3033-3039
    • Bhakat, K.K.1    Hazra, T.K.2    Mitra, S.3
  • 45
    • 35348971904 scopus 로고    scopus 로고
    • Stimulation of NEIL2-mediated oxidized base excision repair via YB-1 interaction during oxidative stress
    • Das S, Chattopadhyay R, Bhakat KK, Boldogh I, Kohno K, et al. (2007) Stimulation of NEIL2-mediated oxidized base excision repair via YB-1 interaction during oxidative stress. J Biol Chem 282: 28474-28484.
    • (2007) J Biol Chem , vol.282 , pp. 28474-28484
    • Das, S.1    Chattopadhyay, R.2    Bhakat, K.K.3    Boldogh, I.4    Kohno, K.5
  • 46
    • 0032574770 scopus 로고    scopus 로고
    • Activation of apurinic/apyrimidinic endonuclease in human cells by reactive oxygen species and its correlation with their adaptive response to genotoxicity of free radicals
    • Ramana CV, Boldogh I, Izumi T, Mitra S, (1998) Activation of apurinic/apyrimidinic endonuclease in human cells by reactive oxygen species and its correlation with their adaptive response to genotoxicity of free radicals. Proc Natl Acad Sci U S A 95: 5061-5066.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 5061-5066
    • Ramana, C.V.1    Boldogh, I.2    Izumi, T.3    Mitra, S.4
  • 47
    • 33644873467 scopus 로고    scopus 로고
    • Two-step cross-linking method for identification of NF-kappaB gene network by chromatin immunoprecipitation
    • Nowak DE, Tian B, Brasier AR, (2005) Two-step cross-linking method for identification of NF-kappaB gene network by chromatin immunoprecipitation. BioTechniques 39: 715-725.
    • (2005) BioTechniques , vol.39 , pp. 715-725
    • Nowak, D.E.1    Tian, B.2    Brasier, A.R.3
  • 49
    • 0033080402 scopus 로고    scopus 로고
    • Transcriptional regulation of the p21((WAF1/CIP1)) gene
    • Gartel AL, Tyner AL, (1999) Transcriptional regulation of the p21((WAF1/CIP1)) gene. Exp Cell Res 246: 280-289.
    • (1999) Exp Cell Res , vol.246 , pp. 280-289
    • Gartel, A.L.1    Tyner, A.L.2
  • 51
    • 65949100126 scopus 로고    scopus 로고
    • The c-MYC-AP4-p21 cascade
    • Jung P, Hermeking H, (2009) The c-MYC-AP4-p21 cascade. Cell cycle 8: 982-989.
    • (2009) Cell Cycle , vol.8 , pp. 982-989
    • Jung, P.1    Hermeking, H.2
  • 52
    • 71049180608 scopus 로고    scopus 로고
    • Complementary quantitative proteomics reveals that transcription factor AP-4 mediates E-box-dependent complex formation for transcriptional repression of HDM2
    • Ku WC, Chiu SK, Chen YJ, Huang HH, Wu WG, (2009) Complementary quantitative proteomics reveals that transcription factor AP-4 mediates E-box-dependent complex formation for transcriptional repression of HDM2. Molecular & cellular proteomics: MCP 8: 2034-2050.
    • (2009) Molecular & Cellular Proteomics: MCP , vol.8 , pp. 2034-2050
    • Ku, W.C.1    Chiu, S.K.2    Chen, Y.J.3    Huang, H.H.4    Wu, W.G.5
  • 54
    • 0031961995 scopus 로고    scopus 로고
    • Effects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication
    • Niculescu AB 3rd, Chen X, Smeets M, Hengst L, Prives C, et al (1998) Effects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication. Molecular and cellular biology 18: 629-643.
    • (1998) Molecular and Cellular Biology , vol.18 , pp. 629-643
    • Niculescu 3rd, A.B.1    Chen, X.2    Smeets, M.3    Hengst, L.4    Prives, C.5
  • 55
    • 0028899480 scopus 로고
    • Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA
    • Chen J, Jackson PK, Kirschner MW, Dutta A, (1995) Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA. Nature 374: 386-388.
    • (1995) Nature , vol.374 , pp. 386-388
    • Chen, J.1    Jackson, P.K.2    Kirschner, M.W.3    Dutta, A.4
  • 58
    • 0028981086 scopus 로고
    • Topological control of p21WAF1/CIP1 expression in normal and neoplastic tissues
    • el-Deiry WS, Tokino T, Waldman T, Oliner JD, Velculescu VE, et al. (1995) Topological control of p21WAF1/CIP1 expression in normal and neoplastic tissues. Cancer Res 55: 2910-2919.
    • (1995) Cancer Res , vol.55 , pp. 2910-2919
    • el-Deiry, W.S.1    Tokino, T.2    Waldman, T.3    Oliner, J.D.4    Velculescu, V.E.5
  • 59
    • 0032486475 scopus 로고    scopus 로고
    • Domain mapping of human apurinic/apyrimidinic endonuclease. Structural and functional evidence for a disordered amino terminus and a tight globular carboxyl domain
    • Strauss PR, Holt CM, (1998) Domain mapping of human apurinic/apyrimidinic endonuclease. Structural and functional evidence for a disordered amino terminus and a tight globular carboxyl domain. J Biol Chem 273: 14435-14441.
    • (1998) J Biol Chem , vol.273 , pp. 14435-14441
    • Strauss, P.R.1    Holt, C.M.2
  • 60
    • 0035890069 scopus 로고    scopus 로고
    • XRCC1 coordinates the initial and late stages of DNA abasic site repair through protein-protein interactions
    • Vidal AE, Boiteux S, Hickson ID, Radicella JP, (2001) XRCC1 coordinates the initial and late stages of DNA abasic site repair through protein-protein interactions. Embo J 20: 6530-6539.
    • (2001) Embo J , vol.20 , pp. 6530-6539
    • Vidal, A.E.1    Boiteux, S.2    Hickson, I.D.3    Radicella, J.P.4
  • 61
    • 63049121360 scopus 로고    scopus 로고
    • APE1/Ref-1 interacts with NPM1 within nucleoli and plays a role in the rRNA quality control process
    • Vascotto C, Fantini D, Romanello M, Cesaratto L, Deganuto M, et al. (2009) APE1/Ref-1 interacts with NPM1 within nucleoli and plays a role in the rRNA quality control process. Mol Cell Biol 29: 1834-1854.
    • (2009) Mol Cell Biol , vol.29 , pp. 1834-1854
    • Vascotto, C.1    Fantini, D.2    Romanello, M.3    Cesaratto, L.4    Deganuto, M.5
  • 62
    • 0036249661 scopus 로고    scopus 로고
    • Influence of p53 status on radiation and 5-flourouracil synergy in pancreatic cancer cells
    • Mohiuddin M, Chendil D, Dey S, Alcock RA, Regine W, et al. (2002) Influence of p53 status on radiation and 5-flourouracil synergy in pancreatic cancer cells. Anticancer research 22: 825-830.
    • (2002) Anticancer Research , vol.22 , pp. 825-830
    • Mohiuddin, M.1    Chendil, D.2    Dey, S.3    Alcock, R.A.4    Regine, W.5
  • 63
    • 37549033163 scopus 로고    scopus 로고
    • Knockdown of the DNA repair and redox signaling protein Ape1/Ref-1 blocks ovarian cancer cell and tumor growth
    • Fishel ML, He Y, Reed AM, Chin-Sinex H, Hutchins GD, et al. (2008) Knockdown of the DNA repair and redox signaling protein Ape1/Ref-1 blocks ovarian cancer cell and tumor growth. DNA Repair (Amst) 7: 177-186.
    • (2008) DNA Repair (Amst) , vol.7 , pp. 177-186
    • Fishel, M.L.1    He, Y.2    Reed, A.M.3    Chin-Sinex, H.4    Hutchins, G.D.5
  • 64
    • 41149097172 scopus 로고    scopus 로고
    • Regulation of the human AP-endonuclease (APE1/Ref-1) expression by the tumor suppressor p53 in response to DNA damage
    • Zaky A, Busso C, Izumi T, Chattopadhyay R, Bassiouny A, et al. (2008) Regulation of the human AP-endonuclease (APE1/Ref-1) expression by the tumor suppressor p53 in response to DNA damage. Nucleic Acids Res.
    • (2008) Nucleic Acids Res
    • Zaky, A.1    Busso, C.2    Izumi, T.3    Chattopadhyay, R.4    Bassiouny, A.5
  • 65
    • 84864881930 scopus 로고    scopus 로고
    • The overexpression of AP-4 as a prognostic indicator for gastric carcinoma
    • Xinghua L, Bo Z, Yan G, Lei W, Changyao W, et al. (2012) The overexpression of AP-4 as a prognostic indicator for gastric carcinoma. Medical oncology 29: 871-877.
    • (2012) Medical Oncology , vol.29 , pp. 871-877
    • Xinghua, L.1    Bo, Z.2    Yan, G.3    Lei, W.4    Changyao, W.5
  • 67
    • 84861217899 scopus 로고    scopus 로고
    • Down-regulation of AP-4 inhibits proliferation, induces cell cycle arrest and promotes apoptosis in human gastric cancer cells
    • Liu X, Zhang B, Guo Y, Liang Q, Wu C, et al. (2012) Down-regulation of AP-4 inhibits proliferation, induces cell cycle arrest and promotes apoptosis in human gastric cancer cells. PloS one 7: e37096.
    • (2012) PloS One , vol.7
    • Liu, X.1    Zhang, B.2    Guo, Y.3    Liang, Q.4    Wu, C.5
  • 68
    • 60849127593 scopus 로고    scopus 로고
    • The Ape-1/Ref-1 redox antagonist E3330 inhibits the growth of tumor endothelium and endothelial progenitor cells: therapeutic implications in tumor angiogenesis
    • Zou GM, Karikari C, Kabe Y, Handa H, Anders RA, et al. (2009) The Ape-1/Ref-1 redox antagonist E3330 inhibits the growth of tumor endothelium and endothelial progenitor cells: therapeutic implications in tumor angiogenesis. Journal of cellular physiology 219: 209-218.
    • (2009) Journal of Cellular Physiology , vol.219 , pp. 209-218
    • Zou, G.M.1    Karikari, C.2    Kabe, Y.3    Handa, H.4    Anders, R.A.5
  • 69
    • 51049091691 scopus 로고    scopus 로고
    • Small-molecule inhibitor of the AP endonuclease 1/REF-1 E3330 inhibits pancreatic cancer cell growth and migration
    • Zou GM, Maitra A, (2008) Small-molecule inhibitor of the AP endonuclease 1/REF-1 E3330 inhibits pancreatic cancer cell growth and migration. Molecular cancer therapeutics 7: 2012-2021.
    • (2008) Molecular Cancer Therapeutics , vol.7 , pp. 2012-2021
    • Zou, G.M.1    Maitra, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.