Resistin impairs SIRT1 function and induces senescence-associated phenotype in hepatocytes

Molecular and Cellular Endocrinology

Volumn 377, Issue 1-2, 2013, Pages 23-32

  Yu, An ^a   Zheng, Yu ^a   Zhang, Rongrong ^b   Huang, Jianfeng ^c   Zhu, Zhoujie ^a   Zhou, Ronghua ^a   Jin, Dan ^a   Yang, Zaiqing ^a  

^a HUAZHONG AGRICULTURAL UNIVERSITY   (China)

^b TULANE UNIVERSITY   (United States)

^c MEDICAL UNIVERSITY OF GRAZ   (Austria)

Author keywords

Hepatocytes; PGC 1 ; PPAR ; Resistin; Senescence associated galactosidase activity; SIRT1

Indexed keywords

BETA GALACTOSIDASE; GLUCOSE; MICRORNA 34A; NICOTINAMIDE NUCLEOTIDE; PALMITIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; RESISTIN; RESVERATROL; SIRTUIN 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ATTENUATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME REGULATION; IN VITRO STUDY; LIVER CELL; LIVER DISEASE; MACROPHAGE; MALE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; SENESCENCE;

HEPATOCYTES; PGC-1Α; PPARΑ; RESISTIN; SENESCENCE-ASSOCIATED Β-GALACTOSIDASE ACTIVITY; SIRT1;

ANIMALS; BETA-GALACTOSIDASE; CELL AGING; DNA; GENE EXPRESSION REGULATION; HEP G2 CELLS; HEPATOCYTES; HUMANS; MALE; MICE; MICE, INBRED C57BL; MICRORNAS; PHENOTYPE; PROTEIN BINDING; RESISTIN; SIRTUIN 1; TRANSCRIPTION, GENETIC;

EID: 84880375883     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2013.06.028     Document Type: Article

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