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Volumn 25, Issue 2, 2013, Pages 225-233

Impact of microRNAs on the understanding and treatment of rheumatoid arthritis

Author keywords

biomarker; miRNA; pathogenesis; rheumatoid arthritis; treatment

Indexed keywords

HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; INTERSTITIAL COLLAGENASE; MICRORNA; MICRORNA 124; MICRORNA 132; MICRORNA 133A; MICRORNA 142 3P; MICRORNA 146A; MICRORNA 150; MICRORNA 155; MICRORNA 16; MICRORNA 203; MICRORNA 221; MICRORNA 222; MICRORNA 223; MICRORNA 23B; MICRORNA 26A; MICRORNA 323 3P; MICRORNA 34A; MICRORNA 363; MICRORNA 498; PROTEIN SH2; STROMELYSIN; TRANSCRIPTION FACTOR FOXP3; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 84873406120     PISSN: 10408711     EISSN: 15316963     Source Type: Journal    
DOI: 10.1097/BOR.0b013e32835d8385     Document Type: Review
Times cited : (64)

References (46)
  • 1
    • 77955434703 scopus 로고    scopus 로고
    • Investigation of potential non-HLA rheu-matoid arthritis susceptibility loci in a European cohort increases the evidence for nine markers
    • Plant D, Flynn E, Mbarek H, et al. Investigation of potential non-HLA rheu-matoid arthritis susceptibility loci in a European cohort increases the evidence for nine markers. Ann Rheum Dis 2010; 69:1548-1553.
    • (2010) Ann Rheum Dis , vol.69 , pp. 1548-1553
    • Plant, D.1    Flynn, E.2    Mbarek, H.3
  • 3
    • 77950625195 scopus 로고    scopus 로고
    • Epigenetictransgenerational actionsofenvironmentalfactors in diseaseetiology
    • Skinner MK, Manikkam M, Guerrero-Bosagna C. Epigenetictransgenerational actionsofenvironmentalfactors in diseaseetiology. Trends Endocrinol Metab 2010; 21:214-222.
    • (2010) Trends Endocrinol Metab , vol.21 , pp. 214-222
    • Skinner, M.K.1    Manikkam, M.2    Guerrero-Bosagna, C.3
  • 4
    • 79957927256 scopus 로고    scopus 로고
    • Inflammatory memories: Is epigenetics the missing linkto persistent stromal cell activation in rheumatoid arthritis?
    • Ospelt C, Reedquist KA, Gay S, et al. Inflammatory memories: is epigenetics the missing linkto persistent stromal cell activation in rheumatoid arthritis? Autoimmun Rev 2011; 10:519-524.
    • (2011) Autoimmun Rev , vol.10 , pp. 519-524
    • Ospelt, C.1    Reedquist, K.A.2    Gay, S.3
  • 5
    • 77950202883 scopus 로고    scopus 로고
    • What can we learn from epigenetics in the year 2009?
    • Jüngel A, Ospelt C, Gay S. What can we learn from epigenetics in the year 2009? Curr Opin Rheumatol 2010; 22:284-292.
    • (2010) Curr Opin Rheumatol , vol.22 , pp. 284-292
    • Jüngel, A.1    Ospelt, C.2    Gay, S.3
  • 7
    • 36149000969 scopus 로고    scopus 로고
    • Clinical and serological features of patientswith autoantibodies to GW/P bodies
    • Bhanji RA, Eystathioy T, Chan EK, et al. Clinical and serological features of patientswith autoantibodies to GW/P bodies. Clin Immunol 2007; 125:247-256.
    • (2007) Clin Immunol , vol.125 , pp. 247-256
    • Bhanji, R.A.1    Eystathioy, T.2    Chan, E.K.3
  • 8
    • 79961025970 scopus 로고    scopus 로고
    • MicroRNAs in body fluids-The mix of hormones and biomarkers
    • Cortez MA, Bueso-Ramos C, Ferdin J, et al. MicroRNAs in body fluids-the mix of hormones and biomarkers. Nat Rev Clin Oncol 2011; 8:467-477.
    • (2011) Nat Rev Clin Oncol , vol.8 , pp. 467-477
    • Cortez, M.A.1    Bueso-Ramos, C.2    Ferdin, J.3
  • 9
    • 52249094653 scopus 로고    scopus 로고
    • Upregulated miR-146a expression in peripheral blood mononuclear cells from rheumatoid arthritis patients
    • Pauley KM, Satoh M, Chan AL, et al. Upregulated miR-146a expression in peripheral blood mononuclear cells from rheumatoid arthritis patients. Arthritis Res Ther 2008; 10:R101.
    • (2008) Arthritis Res Ther , vol.10
    • Pauley, K.M.1    Satoh, M.2    Chan, A.L.3
  • 10
    • 77952086523 scopus 로고    scopus 로고
    • Plasma and synovial fluid microRNAs as potential biomarkers of rheumatoid arthritis and osteoarthritis
    • Murata K, Yoshitomi H, Tanida S, et al. Plasma and synovial fluid microRNAs as potential biomarkers of rheumatoid arthritis and osteoarthritis. Arthritis Res Ther 2010; 12:R86.
    • (2010) Arthritis Res Ther , vol.12
    • Murata, K.1    Yoshitomi, H.2    Tanida, S.3
  • 11
    • 84863686039 scopus 로고    scopus 로고
    • The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-α
    • Zhu S, Pan W, Song X, et al. The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-α. Nat Med 2012; 18:1077-1086.
    • (2012) Nat Med , vol.18 , pp. 1077-1086
    • Zhu, S.1    Pan, W.2    Song, X.3
  • 12
    • 77956511013 scopus 로고    scopus 로고
    • MicroRNA-146a expresses in inter-leukin-17 producing T cells in rheumatoid arthritis patients
    • Niimoto T, Nakasa T, Ishikawa M, et al. MicroRNA-146a expresses in inter-leukin-17 producing T cells in rheumatoid arthritis patients. BMC Musculos-kelet Disord 2010; 11:209.
    • (2010) BMC Musculos-kelet Disord , vol.11 , pp. 209
    • Niimoto, T.1    Nakasa, T.2    Ishikawa, M.3
  • 13
    • 84857887315 scopus 로고    scopus 로고
    • Down-regulation of microRNA-34a&z.ast; In rheumatoid arthritis synovial fibroblasts promotes apoptosis resistance
    • Niederer F, Trenkmann M, Ospelt C, et al. Down-regulation of microRNA-34a&z. ast; in rheumatoid arthritis synovial fibroblasts promotes apoptosis resistance. Arthritis Rheum 2012; 64:1771-1779.
    • (2012) Arthritis Rheum , vol.64 , pp. 1771-1779
    • Niederer, F.1    Trenkmann, M.2    Ospelt, C.3
  • 14
    • 66049112958 scopus 로고    scopus 로고
    • MicroRNA-124a is a key regulator of proliferation and monocyte chemoattractant protein 1 secretion in fibroblast-like synoviocytes from patients with rheumatoid arthritis
    • Nakamachi Y, Kawano S, Takenokuchi M, et al. MicroRNA-124a is a key regulator of proliferation and monocyte chemoattractant protein 1 secretion in fibroblast-like synoviocytes from patients with rheumatoid arthritis. Arthritis Rheum 2009; 60:1294-1304.
    • (2009) Arthritis Rheum , vol.60 , pp. 1294-1304
    • Nakamachi, Y.1    Kawano, S.2    Takenokuchi, M.3
  • 15
    • 42449156220 scopus 로고    scopus 로고
    • Altered expression of microRNA in synovial fibroblasts and synovial tissue in rheumatoid arthritis
    • Stanczyk J, Pedrioli DM, Brentano F, et al. Altered expression of microRNA in synovial fibroblasts and synovial tissue in rheumatoid arthritis. Arthritis Rheum 2008; 58:1001-1009.
    • (2008) Arthritis Rheum , vol.58 , pp. 1001-1009
    • Stanczyk, J.1    Pedrioli, D.M.2    Brentano, F.3
  • 16
    • 43949136123 scopus 로고    scopus 로고
    • Expression of microRNA-146 in rheu-matoid arthritis synovial tissue
    • Nakasa T, Miyaki S, Okubo A, et al. Expression of microRNA-146 in rheu-matoid arthritis synovial tissue. Arthritis Rheum 2008; 58:1284-1292.
    • (2008) Arthritis Rheum , vol.58 , pp. 1284-1292
    • Nakasa, T.1    Miyaki, S.2    Okubo, A.3
  • 17
    • 77951973193 scopus 로고    scopus 로고
    • + T cells from patients with rheumatoid arthritis
    • + T cells from patients with rheumatoid arthritis. Arthritis Res Ther 2010; 12:R81.
    • (2010) Arthritis Res Ther , vol.12
    • Li, J.1    Wan, Y.2    Guo, Q.3
  • 18
    • 79960595150 scopus 로고    scopus 로고
    • MicroRNA-155 as a proinflammatory regulator in clinical and experimental arthritis
    • Kurowska-Stolarska M, Alivernini S, Ballantine LE, et al. MicroRNA-155 as a proinflammatory regulator in clinical and experimental arthritis. Proc Natl Acad Sci USA 2011; 108:11193-11198.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 11193-11198
    • Kurowska-Stolarska, M.1    Alivernini, S.2    Ballantine, L.E.3
  • 19
    • 79551655444 scopus 로고    scopus 로고
    • Altered expression of microRNA-203 in rheumatoid arthritis synovial fibroblasts and its role in fibroblast activation
    • Stanczyk J, Ospelt C, Karouzakis E, et al. Altered expression of microRNA-203 in rheumatoid arthritis synovial fibroblasts and its role in fibroblast activation. Arthritis Rheum 2011; 63:373-381.
    • (2011) Arthritis Rheum , vol.63 , pp. 373-381
    • Stanczyk, J.1    Ospelt, C.2    Karouzakis, E.3
  • 20
    • 84866111542 scopus 로고    scopus 로고
    • Identification of microRNA-221/222 and microRNA-323-3p association with rheumatoid arthritis via predictions using the humantumournecrosisfactortransgenic mouse model
    • Pandis I, Ospelt C, Karagianni N, et al. Identification of microRNA-221/222 and microRNA-323-3p association with rheumatoid arthritis via predictions using the humantumournecrosisfactortransgenic mouse model. Ann Rheum Dis 2012; 71:1716-1723.
    • (2012) Ann Rheum Dis , vol.71 , pp. 1716-1723
    • Pandis, I.1    Ospelt, C.2    Karagianni, N.3
  • 21
    • 74449090482 scopus 로고    scopus 로고
    • MiR-223 is overexpressed in T-lymphocytes of patients affected by rheumatoid arthritis
    • Fulci V, Scappucci G, Sebastiani GD, et al. miR-223 is overexpressed in T-lymphocytes of patients affected by rheumatoid arthritis. Hum Immunol 2010; 71:206-211.
    • (2010) Hum Immunol , vol.71 , pp. 206-211
    • Fulci, V.1    Scappucci, G.2    Sebastiani, G.D.3
  • 22
    • 84880849845 scopus 로고    scopus 로고
    • Overexpression of microRNA-223 in rheumatoid arthritis synovium controls osteoclast differentiation
    • Shibuya H, Nakasa T, Adachi N, et al. Overexpression of microRNA-223 in rheumatoid arthritis synovium controls osteoclast differentiation. Mod Rheu-matol 2012.
    • (2012) Mod Rheu-matol
    • Shibuya, H.1    Nakasa, T.2    Adachi, N.3
  • 23
    • 0038011833 scopus 로고    scopus 로고
    • Evolving concepts of rheumatoid arthritis
    • Firestein GS. Evolving concepts of rheumatoid arthritis. Nature 2003; 423:356-361.
    • (2003) Nature , vol.423 , pp. 356-361
    • Firestein, G.S.1
  • 24
    • 47849125676 scopus 로고    scopus 로고
    • MicroRNAs: New regulators of immune cell development and function
    • Baltimore D, Boldin MP, O'Connell RM, et al. microRNAs: new regulators of immune cell development and function. Nat Immunol 2008; 9:839-845.
    • (2008) Nat Immunol , vol.9 , pp. 839-845
    • Baltimore, D.1    Boldin, M.P.2    O'Connell, R.M.3
  • 25
    • 34247584465 scopus 로고    scopus 로고
    • Requirement of bic/microRNA-155 for normal immune function
    • Rodriguez A, Vigorito E, Clare S, et al. Requirement of bic/microRNA-155 for normal immune function. Science 2007; 316:608-611.
    • (2007) Science , vol.316 , pp. 608-611
    • Rodriguez, A.1    Vigorito, E.2    Clare, S.3
  • 26
    • 33747608638 scopus 로고    scopus 로고
    • NF-KB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses
    • Taganov KD, Boldin MP, Chang KJ, Baltimore D. NF-KB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc Natl Acad Sci USA 2006; 103:12481-12486.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 12481-12486
    • Taganov, K.D.1    Boldin, M.P.2    Chang, K.J.3    Baltimore, D.4
  • 27
    • 67650227725 scopus 로고    scopus 로고
    • MicroRNA-155 modulates the pathogen binding ability of dendritic cells (DCs) by down-regulation of DC-specific intercellular adhesion molecule-3 grabbing nonintegrin (DC-SIGN)
    • Martinez-Nunez RT, Louafi F, Friedmann PS, et al. MicroRNA-155 modulates the pathogen binding ability of dendritic cells (DCs) by down-regulation of DC-specific intercellular adhesion molecule-3 grabbing nonintegrin (DC-SIGN). J Biol Chem 2009; 284:16334-16342.
    • (2009) J Biol Chem , vol.284 , pp. 16334-16342
    • Martinez-Nunez, R.T.1    Louafi, F.2    Friedmann, P.S.3
  • 28
    • 66349137358 scopus 로고    scopus 로고
    • Inositol phosphatase SHIP1 is a primary target of miR-155
    • O'Connell RM, Chaudhuri AA, Rao DS, et al. Inositol phosphatase SHIP1 is a primary target of miR-155. Proc Natl Acad Sci USA 2009; 106:7113-7118.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 7113-7118
    • O'Connell, R.M.1    Chaudhuri, A.A.2    Rao, D.S.3
  • 29
    • 79955561084 scopus 로고    scopus 로고
    • Essential roleof microRNA-155 in the pathogenesis of autoimmune arthritis in mice
    • Blüml S, Bonelli M, Niederreiter B, et al. Essential roleof microRNA-155 in the pathogenesis of autoimmune arthritis in mice. Arthritis Rheum 2011; 63:1281-1288.
    • (2011) Arthritis Rheum , vol.63 , pp. 1281-1288
    • Blüml, S.1    Bonelli, M.2    Niederreiter, B.3
  • 30
    • 68149165370 scopus 로고    scopus 로고
    • MicroRNA-146afeedbackinhibits RIG-I-dependent Type i IFN production in macrophages by targeting TRAF6, IRAK1, and IRAK2
    • Hou J, Wang P, Lin L, et al. MicroRNA-146afeedbackinhibits RIG-I-dependent Type I IFN production in macrophages by targeting TRAF6, IRAK1, and IRAK2. J Immunol 2009; 183:2150-2158.
    • (2009) J Immunol , vol.183 , pp. 2150-2158
    • Hou, J.1    Wang, P.2    Lin, L.3
  • 31
    • 75649108622 scopus 로고    scopus 로고
    • An emerging player in the adaptive immune response: MicroRNA-146a is a modulator of IL-2 expression and activation-induced cell death in T lymphocytes
    • Curtale G, Citarella F, Carissimi C, et al. An emerging player in the adaptive immune response: microRNA-146a is a modulator of IL-2 expression and activation-induced cell death in T lymphocytes. Blood 2010; 115:265-273.
    • (2010) Blood , vol.115 , pp. 265-273
    • Curtale, G.1    Citarella, F.2    Carissimi, C.3
  • 32
    • 77958061493 scopus 로고    scopus 로고
    • Diazoxide potentiates mesenchymal stem cell survival viaNF-kappaB- dependentmiR-146aexpression bytargeting Fas
    • Suzuki Y, Kim HW, Ashraf M, et al. Diazoxide potentiates mesenchymal stem cell survival viaNF-kappaB-dependentmiR-146aexpression bytargeting Fas. Am J Physiol Heart Circ Physiol 2010; 299:H1077-H1082.
    • (2010) Am J Physiol Heart Circ Physiol , vol.299
    • Suzuki, Y.1    Kim, H.W.2    Ashraf, M.3
  • 33
    • 39849096995 scopus 로고    scopus 로고
    • Regulation of progenitor cell proliferation and granulocyte function by microRNA-223
    • Johnnidis JB, Harris MH, Wheeler RT, et al. Regulation of progenitor cell proliferation and granulocyte function by microRNA-223. Nature 2008; 451:1125-1129.
    • (2008) Nature , vol.451 , pp. 1125-1129
    • Johnnidis, J.B.1    Harris, M.H.2    Wheeler, R.T.3
  • 34
    • 58049186787 scopus 로고    scopus 로고
    • Suppression of LPS-induced Interferon-gamma and nitric oxide in splenic lymphocytes by select estrogen-regulated microRNAs: A novel mechanism of immune modulation
    • Dai R, Phillips RA, Zhang Y, et al. Suppression of LPS-induced Interferon-gamma and nitric oxide in splenic lymphocytes by select estrogen-regulated microRNAs: a novel mechanism of immune modulation. Blood 2008; 112: 4591-4597.
    • (2008) Blood , vol.112 , pp. 4591-4597
    • Dai, R.1    Phillips, R.A.2    Zhang, Y.3
  • 36
    • 84862150859 scopus 로고    scopus 로고
    • A novel regulator of macrophage activation: MiR-223 in obesity-associated adipose tissue inflammation
    • Zhuang G, Meng C, Guo X, et al. A novel regulator of macrophage activation: miR-223 in obesity-associated adipose tissue inflammation. Circulation 2012; 125:2892-2903.
    • (2012) Circulation , vol.125 , pp. 2892-2903
    • Zhuang, G.1    Meng, C.2    Guo, X.3
  • 37
    • 84867320879 scopus 로고    scopus 로고
    • Cutting edge: MiR-223 and EBV miR-BART15 regulate the NLRP3 inflammasome and IL-1 β produc-tion
    • Haneklaus M, Gerlic M, Kurowska-Stolarska M, et al. Cutting edge: miR-223 and EBV miR-BART15 regulate the NLRP3 inflammasome and IL-1 β produc-tion. J Immunol 2012; 189:3795-3799.
    • (2012) J Immunol , vol.189 , pp. 3795-3799
    • Haneklaus, M.1    Gerlic, M.2    Kurowska-Stolarska, M.3
  • 38
    • 33947583822 scopus 로고    scopus 로고
    • Osteoimmunology: Shared mechanisms and crosstalk between the immune and bone systems
    • Takayani H. Osteoimmunology: shared mechanisms and crosstalk between the immune and bone systems. Nat Rev Immunol 2007; 7:292-304.
    • (2007) Nat Rev Immunol , vol.7 , pp. 292-304
    • Takayani, H.1
  • 39
    • 63249113375 scopus 로고    scopus 로고
    • Impaired microRNA pathways diminish osteoclast differentiation and function
    • Suganati T, Hruska KA. Impaired microRNA pathways diminish osteoclast differentiation and function. J Biol Chem 2009; 284:4667-4678.
    • (2009) J Biol Chem , vol.284 , pp. 4667-4678
    • Suganati, T.1    Hruska, K.A.2
  • 40
    • 84864780886 scopus 로고    scopus 로고
    • MiR-155 modulates TNF-α-inhibited osteo-genic differentiation by targeting SOCS1 expression
    • Wua T, Xiea M, Wanga X, et al. miR-155 modulates TNF-α-inhibited osteo-genic differentiation by targeting SOCS1 expression. Bone 2012; 51:498-505.
    • (2012) Bone , vol.51 , pp. 498-505
    • Wua, T.1    Xiea, M.2    Wanga, X.3
  • 41
    • 79958053053 scopus 로고    scopus 로고
    • The inhibitory effect of microRNA-146a expression on bone destruction in collagen-induced arthritis
    • Nakasa T, Shibuya H, Nagata Y, et al. The inhibitory effect of microRNA-146a expression on bone destruction in collagen-induced arthritis. Arthritis Rheum 2011; 63:1582-1590.
    • (2011) Arthritis Rheum , vol.63 , pp. 1582-1590
    • Nakasa, T.1    Shibuya, H.2    Nagata, Y.3
  • 42
    • 0141989771 scopus 로고    scopus 로고
    • Receptor activator of NF-kappa B ligand stimulates recruitment of SHP-1 to the complex containing TNFR-associated factor 6 that regulates osteoclastogenesis
    • Zhang Z, Jimi E, Bothwell AL. Receptor activator of NF-kappa B ligand stimulates recruitment of SHP-1 to the complex containing TNFR-associated factor 6 that regulates osteoclastogenesis. J Immunol 2003; 171:3620-3626.
    • (2003) J Immunol , vol.171 , pp. 3620-3626
    • Zhang, Z.1    Jimi, E.2    Bothwell, A.L.3
  • 43
    • 84862263981 scopus 로고    scopus 로고
    • TRAF-6 dependent signaling pathway is essential for TNF-related apoptosis-inducing ligand (TRAIL) induces osteo-clast differentiation
    • Yen ML, Hsu PN, Liao HJ, et al. TRAF-6 dependent signaling pathway is essential for TNF-related apoptosis-inducing ligand (TRAIL) induces osteo-clast differentiation. PLoS One 2012; 7:e38048.
    • (2012) PLoS One , vol.7
    • Yen, M.L.1    Hsu, P.N.2    Liao, H.J.3
  • 44
    • 0034735842 scopus 로고    scopus 로고
    • Infliximab and methotrexate in the treatment of rheumatoid arthritis. Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy Study Group
    • Lipsky PE, van der Heijde DM, St Clair EW, et al. Infliximab and methotrexate in the treatment of rheumatoid arthritis. Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy Study Group. N Engl J Med 2000; 343:1594-1602.
    • (2000) N Engl J Med , vol.343 , pp. 1594-1602
    • Lipsky, P.E.1    Van Der Heijde, D.M.2    St Clair, E.W.3
  • 45
    • 40849112979 scopus 로고    scopus 로고
    • Activation of peroxisome pro-liferator-activated receptor gamma inhibits TNF-alpha-mediated osteoclast differentiation in human peripheral monocytes in partviasuppression of mono-cyte chemoattractant protein-1 expression
    • Hounoki H, Sugiyama E, Mohamed SG, et al. Activation of peroxisome pro-liferator-activated receptor gamma inhibits TNF-alpha-mediated osteoclast differentiation in human peripheral monocytes in partviasuppression of mono-cyte chemoattractant protein-1 expression. Bone 2008; 42:765-774.
    • (2008) Bone , vol.42 , pp. 765-774
    • Hounoki, H.1    Sugiyama, E.2    Mohamed, S.G.3
  • 46
    • 84869063724 scopus 로고    scopus 로고
    • Briefreport:amelioration ofcollagen-induced arthritis in mice by lentivirus-mediated silencing of microRNA-223
    • Li YT, Chen SY, Wang CR, et al. Briefreport:amelioration ofcollagen-induced arthritis in mice by lentivirus-mediated silencing of microRNA-223. Arthritis Rheum 2012; 64:3240-3245.
    • (2012) Arthritis Rheum , vol.64 , pp. 3240-3245
    • Li, Y.T.1    Chen, S.Y.2    Wang, C.R.3


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