Comparative study on the level of B lymphocyte stimulator (BlyS) and frequency of lymphocytes between sero-negative and sero-positive rheumatoid arthritis patients

International Journal of Rheumatic Diseases

Volumn 15, Issue 5, 2012, Pages 478-485

  Geng, Yan ^a   Zhang, Zhuo li ^a  

^a PEKING UNIVERSITY FIRST HOSPITAL   (China)

Author keywords

B lymphocyte stimulator (BlyS); Rheumatoid arthritis; Sero negative; Sero positive

Indexed keywords

B CELL ACTIVATING FACTOR; C REACTIVE PROTEIN; CYCLIC CITRULLINATED PEPTIDE ANTIBODY; RHEUMATOID FACTOR;

ADULT; ANTIBODY TITER; ARTICLE; B LYMPHOCYTE; COMPARATIVE STUDY; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE ACTIVITY; ERYTHROCYTE SEDIMENTATION RATE; FEMALE; FLOW CYTOMETRY; HELPER CELL; HUMAN; HUMAN CELL; LYMPHOCYTE; LYMPHOCYTE ACTIVATION; MAJOR CLINICAL STUDY; MALE; OSTEOARTHRITIS; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROGNOSIS; RADIODIAGNOSIS; RHEUMATOID ARTHRITIS; SCORING SYSTEM; SEROLOGY; T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION;

ADULT; AGED; ARTHRITIS, RHEUMATOID; B-CELL ACTIVATING FACTOR; B-LYMPHOCYTES; BIOLOGICAL MARKERS; BLOOD SEDIMENTATION; C-REACTIVE PROTEIN; FEMALE; HUMANS; MALE; MIDDLE AGED; OSTEOARTHRITIS; PROGNOSIS; SEVERITY OF ILLNESS INDEX; T-LYMPHOCYTES; T-LYMPHOCYTES, HELPER-INDUCER;

EID: 84867905581     PISSN: 17561841     EISSN: 1756185X     Source Type: Journal    
DOI: 10.1111/j.1756-185X.2012.01814.x     Document Type: Article

References (26)

1. Porter D, Madhok R, Capell H (1991) Non-Hodgkin's lymphoma in rheumatoid arthritis. Ann Rheum Dis 50, 275-6.
2. Atzeni F, Doria A, Turiel M, Sarzi-Puttini P (2007) What is the role of rituximab in the treatment of rheumatoid arthritis? Autoimmun Rev 6, 553-8.
3. Moore PA, Belvedere O, Orr A et al. (1999) BlyS: member of the tumor necrosis factor family and B lymphocyte stimulator. Science 285, 260-3.
4. Pers JO, Daridon C, Devauchelle V et al. (2005) BAFF overexpression is associated with autoantibody production in autoimmune diseases. Ann N Y Acad Sci 1050, 34-9.
5. Mackay F, Sierro F, Grey ST, Gordon TP (2005) The BAFF/APRIL system: an important player in systemic rheumatic diseases. Curr Dir Autoimmun 8, 243-65.
6. Schaller M, Stohl W, Tan SM, Benoit VM, Hilbert DM, Ditzel HJ (2005) Raised levels of anti-glucose-6-phosphate isomerase IgG in serum and synovial fluid from patients with inflammatory arthritis. Ann Rheum Dis 64, 743-9.
7. Cheema GS, Roschke V, Hilbert DM, Stohl W (2001) Elevated serum B lymphocyte stimulator levels in patients with systemic immune-based rheumatic diseases. Arthritis Rheum 44, 1313-9.
8. Tan SM, Xu D, Roschke V et al. (2003) Local production of B lymphocyte stimulator protein and APRIL in arthritic joints of patients with inflammatory arthritis. Arthritis Rheum 48, 982-92.
9. Bosello S, Youinou P, Daridon C et al. (2008) Concentrations of BAFF correlate with autoantibody levels, clinical disease activity, and response to treatment in early rheumatoid arthritis. J Rheumatol 35, 1256-64.
10. Gottenberg JE, Miceli-Richard C, Ducot B, Goupille P, Combe B, Mariette X (2009) Markers of B-lymphocyte activation are elevated in patients with early rheumatoid arthritis and correlated with disease activity in the ESPOIR cohort. Arthritis Res Ther 11, R114.
11. Mackay F, Woodcock SA, Lawton P et al. (1999) Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations. J Exp Med 190, 1697-710.
12. Khare SD, Sarosi I, Xia XZ et al. (2000) Severe B cell hyperplasia and autoimmune disease in TALL-1 transgenic mice. Proc Natl Acad Sci USA 97, 3370-5.
13. Schiemann B, Gommerman JL, Vora K et al. (2001) An essential role for BAFF in the normal development of B cells through a BCMA-independent pathway. Science 293, 2111-4.
14. Gross JA, Dillon SR, Mudri S et al. (2001) TACI-Ig neutralizes molecules critical for B cell development and autoimmune disease. impaired B cell maturation in mice lacking BlyS. Immunity 15, 289-302.
15. von Bulow GU, van Deursen JM, Bram RJ (2001) Regulation of the T-independent humoral response by TACI. Immunity 14, 573-82.
16. Yan M, Wang H, Chan B et al. (2001) Activation and accumulation of B cells in TACI-deficient mice. Nat Immunol 2, 638-43.
17. Cambridge G, Stohl W, Leandro MJ, Migone TS, Hilbert DM, Edwards JC (2006) Circulating levels of B lymphocyte stimulator in patients with rheumatoid arthritis following rituximab treatment: relationships with B cell depletion, circulating antibodies, and clinical relapse. Arthritis Rheum 54, 723-32.
18. Buchan G, Barrett K, Turner M, Chantry D, Maini RN, Feldmann M (1988) Interleukin-1 and tumor necrosis factor mRNA expression in rheumatoid arthritis: prolonged production of IL-1 alpha. Clin Exp Immunol 73, 449-55.
19. Miossec P, van den Berg W (1997) Th1/Th2 cytokine balance in arthritis. Arthritis Rheum 40, 2105-15.
20. Chen DY, Lan JL, Lin FJ, Hsieh TY, Wen MC (2004) Predominance of Th1 cytokine in peripheral blood and pathological tissues of patients with active untreated adult onset Still's disease. Ann Rheum Dis 63, 1300-6.
21. Aarvak T, Chabaud M, Thoen J, Miossec P, Natvig JB (2000) Changes in the Th1 or Th2 cytokine dominance in the synovium of rheumatoid arthritis (RA): a kinetic study of the Th subsets in one unusual RA patient. Rheumatology (Oxford) 39, 513-22.
22. Stockinger B, Veldhoen M (2007) Differentiation and function of Th17 T cells. Curr Opin Immunol 19, 281-6.
23. Chabaud M, Durand JM, Buchs N et al. (1999) Human interleukin-17: a T cell-derived proinflammatory cytokine produced by the rheumatoid synovium. Arthritis Rheum 42, 963-70.
24. Kotake S, Udagawa N, Takahashi N et al. (1999) IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis. J Clin Invest 103, 1345-52.
25. Shahrara S, Huang Q, Mandelin AM II, Pope RM (2008) TH-17 cells in rheumatoid arthritis. Arthritis Res Ther 10, R93.
26. Lai Kwan Lam Q, King Hung Ko O, Zheng BJ, Lu L (2008) Local BAFF gene silencing suppresses Th17-cell generation and ameliorates autoimmune arthritis. Proc Natl Acad Sci USA 105, 14993-8.