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Volumn 162, Issue 2, 2013, Pages 162-176

MicroRNAs in myeloid malignancies

Author keywords

Acute myeloid leukaemia; Chronic myeloid leukaemia; Leukaemia; MicroRNAs; Myeloid

Indexed keywords

BCR ABL PROTEIN; BCR ABL1 PROTEIN; CORE BINDING FACTOR; MESSENGER RNA; MICRORNA; MICRORNA 125B; MICRORNA 125B2; MICRORNA 126; MICRORNA 142 3P; MICRORNA 150; MICRORNA 17HG; MICRORNA 181A; MICRORNA 181B; MICRORNA 196B; MICRORNA 223; MICRORNA 29; MICRORNA 29A; MICRORNA 328; MICRORNA 495; NUCLEOPHOSMIN; TRANSCRIPTION FACTOR ERG; TRANSCRIPTION FACTOR RUNX1; TUMOR MARKER; UNCLASSIFIED DRUG;

EID: 84879839817     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/bjh.12364     Document Type: Review
Times cited : (40)

References (151)
  • 2
    • 0021771445 scopus 로고
    • Heterochronic mutants of the nematode Caenorhabditis elegans
    • Ambros, V. & Horvitz, H.R. (1984) Heterochronic mutants of the nematode Caenorhabditis elegans. Science, 226, 409-416.
    • (1984) Science , vol.226 , pp. 409-416
    • Ambros, V.1    Horvitz, H.R.2
  • 7
    • 81355123438 scopus 로고    scopus 로고
    • Evolution of microRNA diversity and regulation in animals
    • Berezikov, E. (2011) Evolution of microRNA diversity and regulation in animals. Nature Reviews Genetics, 12, 846-860.
    • (2011) Nature Reviews Genetics , vol.12 , pp. 846-860
    • Berezikov, E.1
  • 12
    • 79551499254 scopus 로고    scopus 로고
    • Human box C/D snoRNAs with miRNA like functions: expanding the range of regulatory RNAs
    • Brameier, M., Herwig, A., Reinhardt, R., Walter, L. & Gruber, J. (2011) Human box C/D snoRNAs with miRNA like functions: expanding the range of regulatory RNAs. Nucleic Acids Research, 39, 675-686.
    • (2011) Nucleic Acids Research , vol.39 , pp. 675-686
    • Brameier, M.1    Herwig, A.2    Reinhardt, R.3    Walter, L.4    Gruber, J.5
  • 13
    • 0037418839 scopus 로고    scopus 로고
    • Bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila
    • Brennecke, J., Hipfner, D.R., Stark, A., Russell, R.B. & Cohen, S.M. (2003) Bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila. Cell, 113, 25-36.
    • (2003) Cell , vol.113 , pp. 25-36
    • Brennecke, J.1    Hipfner, D.R.2    Stark, A.3    Russell, R.B.4    Cohen, S.M.5
  • 15
  • 16
    • 84857136301 scopus 로고    scopus 로고
    • miR-10a is aberrantly overexpressed in Nucleophosmin1 mutated acute myeloid leukaemia and its suppression induces cell death
    • Bryant, A., Palma, C.A., Jayaswal, V., Yang, Y.W., Lutherborrow, M. & Ma, D.D. (2012) miR-10a is aberrantly overexpressed in Nucleophosmin1 mutated acute myeloid leukaemia and its suppression induces cell death. Molecular Cancer, 11, 8.
    • (2012) Molecular Cancer , vol.11 , pp. 8
    • Bryant, A.1    Palma, C.A.2    Jayaswal, V.3    Yang, Y.W.4    Lutherborrow, M.5    Ma, D.D.6
  • 23
    • 22244467087 scopus 로고    scopus 로고
    • MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells
    • Chan, J.A., Krichevsky, A.M. & Kosik, K.S. (2005) MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Research, 65, 6029-6033.
    • (2005) Cancer Research , vol.65 , pp. 6029-6033
    • Chan, J.A.1    Krichevsky, A.M.2    Kosik, K.S.3
  • 25
    • 77953183812 scopus 로고    scopus 로고
    • A dicer-independent miRNA biogenesis pathway that requires Ago catalysis
    • Cheloufi, S., Dos Santos, C.O., Chong, M.M.W. & Hannon, G.J. (2010) A dicer-independent miRNA biogenesis pathway that requires Ago catalysis. Nature, 465, 584-589.
    • (2010) Nature , vol.465 , pp. 584-589
    • Cheloufi, S.1    Dos Santos, C.O.2    Chong, M.M.W.3    Hannon, G.J.4
  • 28
    • 84878445471 scopus 로고    scopus 로고
    • A polymorphism in the 3′-untranslated region of the NPM1 gene causes illegitimate regulation by microRNA-337-5p and correlates with adverse outcome in acute myeloid leukemia
    • doi: 10.3324/haematol.2012.073015.
    • Cheng, C.K., Kwan, T.K., Cheung, C.Y., Ng, K., Liang, P., Cheng, S.H., Chan, N.P., Ip, R.K., Wong, R.S., Lee, V., Li, C.K., Yip, S.F. & Ng, M.H. (2012) A polymorphism in the 3′-untranslated region of the NPM1 gene causes illegitimate regulation by microRNA-337-5p and correlates with adverse outcome in acute myeloid leukemia. Haematologica, doi: 10.3324/haematol.2012.073015.
    • (2012) Haematologica
    • Cheng, C.K.1    Kwan, T.K.2    Cheung, C.Y.3    Ng, K.4    Liang, P.5    Cheng, S.H.6    Chan, N.P.7    Ip, R.K.8    Wong, R.S.9    Lee, V.10    Li, C.K.11    Yip, S.F.12    Ng, M.H.13
  • 32
    • 0025117392 scopus 로고
    • Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome
    • Daley, G.Q., Van Etten, R.A. & Baltimore, D. (1990) Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome. Science, 247, 824-830.
    • (1990) Science , vol.247 , pp. 824-830
    • Daley, G.Q.1    Van Etten, R.A.2    Baltimore, D.3
  • 37
  • 39
    • 84859632747 scopus 로고    scopus 로고
    • miRNA-mediated gene silencing by translational repression followed by mRNA deadenylation and decay
    • Djuranovic, S., Nahvi, A. & Green, R. (2012) miRNA-mediated gene silencing by translational repression followed by mRNA deadenylation and decay. Science, 336, 237-240.
    • (2012) Science , vol.336 , pp. 237-240
    • Djuranovic, S.1    Nahvi, A.2    Green, R.3
  • 40
    • 78149303249 scopus 로고    scopus 로고
    • MicroRNA sponges: progress and possibilities
    • Ebert, M.S. & Sharp, P.A. (2010) MicroRNA sponges: progress and possibilities. RNA, 16, 2043-2050.
    • (2010) RNA , vol.16 , pp. 2043-2050
    • Ebert, M.S.1    Sharp, P.A.2
  • 41
    • 34548316982 scopus 로고    scopus 로고
    • MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells
    • Ebert, M.S., Neilson, J.R. & Sharp, P.A. (2007) MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells. Nature Methods, 4, 721-726.
    • (2007) Nature Methods , vol.4 , pp. 721-726
    • Ebert, M.S.1    Neilson, J.R.2    Sharp, P.A.3
  • 45
    • 77954647669 scopus 로고    scopus 로고
    • The tumour-suppressive miR-29a/b1 cluster is regulated by CEBPA and blocked in human AML
    • Eyholzer, M., Schmid, S., Wilkens, L., Mueller, B.U. & Pabst, T. (2010) The tumour-suppressive miR-29a/b1 cluster is regulated by CEBPA and blocked in human AML. British Journal of Cancer, 103, 275-284.
    • (2010) British Journal of Cancer , vol.103 , pp. 275-284
    • Eyholzer, M.1    Schmid, S.2    Wilkens, L.3    Mueller, B.U.4    Pabst, T.5
  • 46
    • 79958776230 scopus 로고    scopus 로고
    • Role of microRNAs in lymphoid biology and disease
    • Fabbri, M. & Croce, C.M. (2011) Role of microRNAs in lymphoid biology and disease. Current opinion in hematology, 18, 266-272.
    • (2011) Current opinion in hematology , vol.18 , pp. 266-272
    • Fabbri, M.1    Croce, C.M.2
  • 47
    • 28344438648 scopus 로고    scopus 로고
    • A minicircuitry comprised of microRNA-223 and transcription factors NFI-A and C/EBPalpha regulates human granulopoiesis
    • Fazi, F., Rosa, A., Fatica, A., Gelmetti, V., De Marchis, M.L., Nervi, C. & Bozzoni, I. (2005) A minicircuitry comprised of microRNA-223 and transcription factors NFI-A and C/EBPalpha regulates human granulopoiesis. Cell, 123, 819-831.
    • (2005) Cell , vol.123 , pp. 819-831
    • Fazi, F.1    Rosa, A.2    Fatica, A.3    Gelmetti, V.4    De Marchis, M.L.5    Nervi, C.6    Bozzoni, I.7
  • 49
    • 84863357550 scopus 로고    scopus 로고
    • miR-181a post-transcriptionally downregulates oncogenic RalA and contributes to growth inhibition and apoptosis in chronic myelogenous leukemia (CML)
    • Fei, J., Li, Y., Zhu, X. & Luo, X. (2012) miR-181a post-transcriptionally downregulates oncogenic RalA and contributes to growth inhibition and apoptosis in chronic myelogenous leukemia (CML). PLoS One, 7, e32834.
    • (2012) PLoS One , vol.7
    • Fei, J.1    Li, Y.2    Zhu, X.3    Luo, X.4
  • 53
    • 79961171626 scopus 로고    scopus 로고
    • MicroRNA-193a represses c-kit expression and functions as a methylation-silenced tumor suppressor in acute myeloid leukemia
    • Gao, X.N., Lin, J., Li, Y.H., Gao, L., Wang, X.R., Wang, W., Kang, H.Y., Yan, G.T., Wang, L.L. & Yu, L. (2011a) MicroRNA-193a represses c-kit expression and functions as a methylation-silenced tumor suppressor in acute myeloid leukemia. Oncogene, 30, 3416-3428.
    • (2011) Oncogene , vol.30 , pp. 3416-3428
    • Gao, X.N.1    Lin, J.2    Li, Y.H.3    Gao, L.4    Wang, X.R.5    Wang, W.6    Kang, H.Y.7    Yan, G.T.8    Wang, L.L.9    Yu, L.10
  • 54
    • 80051472789 scopus 로고    scopus 로고
    • MicroRNA-193b regulates c-Kit proto-oncogene and represses cell proliferation in acute myeloid leukemia
    • Gao, X.N., Lin, J., Gao, L., Li, Y.H., Wang, L.L. & Yu, L. (2011b) MicroRNA-193b regulates c-Kit proto-oncogene and represses cell proliferation in acute myeloid leukemia. Leukemia Research, 35, 1226-1232.
    • (2011) Leukemia Research , vol.35 , pp. 1226-1232
    • Gao, X.N.1    Lin, J.2    Gao, L.3    Li, Y.H.4    Wang, L.L.5    Yu, L.6
  • 60
    • 77957361864 scopus 로고    scopus 로고
    • Targeting microRNAs in cancer: rationale, strategies and challenges
    • Garzon, R., Marcucci, G. & Croce, C.M. (2010) Targeting microRNAs in cancer: rationale, strategies and challenges. Nature Reviews Drug Discovery, 9, 775-789.
    • (2010) Nature Reviews Drug Discovery , vol.9 , pp. 775-789
    • Garzon, R.1    Marcucci, G.2    Croce, C.M.3
  • 61
    • 0036720398 scopus 로고    scopus 로고
    • The roles of FLT3 in hematopoiesis and leukemia
    • Gilliland, D.G. & Griffin, J.D. (2002) The roles of FLT3 in hematopoiesis and leukemia. Blood, 100, 1532-1542.
    • (2002) Blood , vol.100 , pp. 1532-1542
    • Gilliland, D.G.1    Griffin, J.D.2
  • 63
    • 0034673638 scopus 로고    scopus 로고
    • An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
    • Hammond, S.M., Bernstein, E., Beach, D. & Hannon, G.J. (2000) An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells. Nature, 404, 293-296.
    • (2000) Nature , vol.404 , pp. 293-296
    • Hammond, S.M.1    Bernstein, E.2    Beach, D.3    Hannon, G.J.4
  • 64
    • 77949518018 scopus 로고    scopus 로고
    • microRNA-29a induces aberrant self-renewal capacity in hematopoietic progenitors, biased myeloid development, and acute myeloid leukemia
    • Han, Y.C., Park, C.Y., Bhagat, G., Zhang, J., Wang, Y., Fan, J.B., Liu, M., Zou, Y., Weissman, I.L. & Gu, H. (2010) microRNA-29a induces aberrant self-renewal capacity in hematopoietic progenitors, biased myeloid development, and acute myeloid leukemia. Journal of Experimental Medicine, 207, 475-489.
    • (2010) Journal of Experimental Medicine , vol.207 , pp. 475-489
    • Han, Y.C.1    Park, C.Y.2    Bhagat, G.3    Zhang, J.4    Wang, Y.5    Fan, J.B.6    Liu, M.7    Zou, Y.8    Weissman, I.L.9    Gu, H.10
  • 65
    • 78649526236 scopus 로고    scopus 로고
    • MicroRNAs: emerging key regulators of hematopoiesis
    • Havelange, V. & Garzon, R. (2010) MicroRNAs: emerging key regulators of hematopoiesis. American Journal of Hematology, 85, 935-942.
    • (2010) American Journal of Hematology , vol.85 , pp. 935-942
    • Havelange, V.1    Garzon, R.2
  • 67
    • 33845263501 scopus 로고    scopus 로고
    • High meningioma 1 (MN1) expression as a predictor for poor outcome in acute myeloid leukemia with normal cytogenetics
    • Heuser, M., Beutel, G., Krauter, J., Döhner, K., von Neuhoff, N., Schlegelberger, B. & Ganser, A. (2006) High meningioma 1 (MN1) expression as a predictor for poor outcome in acute myeloid leukemia with normal cytogenetics. Blood, 108, 3898-3905.
    • (2006) Blood , vol.108 , pp. 3898-3905
    • Heuser, M.1    Beutel, G.2    Krauter, J.3    Döhner, K.4    von Neuhoff, N.5    Schlegelberger, B.6    Ganser, A.7
  • 68
    • 0035800521 scopus 로고    scopus 로고
    • A cellular function for the RNA-interference enzyme dicer in the maturation of the let-7 small temporal RNA
    • Hutvägner, G., McLachlan, J., Pasquinelli, A.E., Bálint, É., Tuschl, T. & Zamore, P.D. (2001) A cellular function for the RNA-interference enzyme dicer in the maturation of the let-7 small temporal RNA. Science, 293, 834-838.
    • (2001) Science , vol.293 , pp. 834-838
    • Hutvägner, G.1    McLachlan, J.2    Pasquinelli, A.E.3    Bálint, E.4    Tuschl, T.5    Zamore, P.D.6
  • 71
    • 46749108531 scopus 로고    scopus 로고
    • MicroRNA expression profiling in relation to the genetic heterogeneity of acute myeloid leukemia
    • Jongen-Lavrencic, M., Sun, S.M., Dijkstra, M.K., Valk, P.J. & Löwenberg, B. (2008) MicroRNA expression profiling in relation to the genetic heterogeneity of acute myeloid leukemia. Blood, 111, 5078-5085.
    • (2008) Blood , vol.111 , pp. 5078-5085
    • Jongen-Lavrencic, M.1    Sun, S.M.2    Dijkstra, M.K.3    Valk, P.J.4    Löwenberg, B.5
  • 72
    • 84867304399 scopus 로고    scopus 로고
    • Spi-1, Fli-1 and Fli-3 (miR-17-92) oncogenes contribute to a single oncogenic network controlling cell proliferation in Friend Erythroleukemia
    • Kayali, S., Giraud, G., Morlé, F. & Guyot, B. (2012) Spi-1, Fli-1 and Fli-3 (miR-17-92) oncogenes contribute to a single oncogenic network controlling cell proliferation in Friend Erythroleukemia. PLoS One, 7, e46799.
    • (2012) PLoS One , vol.7
    • Kayali, S.1    Giraud, G.2    Morlé, F.3    Guyot, B.4
  • 73
    • 84866125820 scopus 로고    scopus 로고
    • MicroRNA-16 is down-regulated in mutated FLT3 expressing murine myeloid FDC-P1 cells and interacts with Pim-1
    • Kim, K.T., Carroll, A.P., Mashkani, B., Cairns, M.J., Small, D. & Scott, R.J. (2012) MicroRNA-16 is down-regulated in mutated FLT3 expressing murine myeloid FDC-P1 cells and interacts with Pim-1. PLoS One, 7, e44546.
    • (2012) PLoS One , vol.7
    • Kim, K.T.1    Carroll, A.P.2    Mashkani, B.3    Cairns, M.J.4    Small, D.5    Scott, R.J.6
  • 79
    • 0035955374 scopus 로고    scopus 로고
    • Identification of novel genes coding for small expressed RNAs
    • Lagos-Quintana, M., Rauhut, R., Lendeckel, W. & Tuschl, T. (2001) Identification of novel genes coding for small expressed RNAs. Science, 294, 853-858.
    • (2001) Science , vol.294 , pp. 853-858
    • Lagos-Quintana, M.1    Rauhut, R.2    Lendeckel, W.3    Tuschl, T.4
  • 80
    • 10344248903 scopus 로고    scopus 로고
    • The human DiGeorge Syndrome Critical Region Gene 8 and its D. melanogaster homolog are required for miRNA biogenesis
    • Landthaler, M., Yalcin, A. & Tuschl, T. (2004) The human DiGeorge Syndrome Critical Region Gene 8 and its D. melanogaster homolog are required for miRNA biogenesis. Current Biology, 14, 2162-2167.
    • (2004) Current Biology , vol.14 , pp. 2162-2167
    • Landthaler, M.1    Yalcin, A.2    Tuschl, T.3
  • 82
    • 0035955361 scopus 로고    scopus 로고
    • An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans
    • Lau, N.C., Lim, L.P., Weinstein, E.G. & Bartel, D.P. (2001) An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science, 294, 858-862.
    • (2001) Science , vol.294 , pp. 858-862
    • Lau, N.C.1    Lim, L.P.2    Weinstein, E.G.3    Bartel, D.P.4
  • 84
    • 0027751663 scopus 로고
    • The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • Lee, R.C., Feinbaum, R.L. & Ambros, V. (1993) The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell, 75, 843-854.
    • (1993) Cell , vol.75 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 86
    • 83255194160 scopus 로고    scopus 로고
    • Chemical modification and design of anti-miRNA oligonucleotides
    • Lennox, K.A. & Behlke, M.A. (2011) Chemical modification and design of anti-miRNA oligonucleotides. Gene Therapy, 18, 1111-1120.
    • (2011) Gene Therapy , vol.18 , pp. 1111-1120
    • Lennox, K.A.1    Behlke, M.A.2
  • 87
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
    • Lewis, B.P., Burge, C.B. & Bartel, D.P. (2005) Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell, 120, 15-20.
    • (2005) Cell , vol.120 , pp. 15-20
    • Lewis, B.P.1    Burge, C.B.2    Bartel, D.P.3
  • 90
    • 84861048490 scopus 로고    scopus 로고
    • The miR-17-92 cluster expands multipotent hematopoietic progenitors whereas imbalanced expression of its individual oncogenic miRNAs promotes leukemia in mice
    • Li, Y., Vecchiarelli-Federico, L.M., Li, Y.J., Egan, S.E., Spaner, D., Hough, M.R. & Ben-David, Y. (2012b) The miR-17-92 cluster expands multipotent hematopoietic progenitors whereas imbalanced expression of its individual oncogenic miRNAs promotes leukemia in mice. Blood, 119, 4486-4498.
    • (2012) Blood , vol.119 , pp. 4486-4498
    • Li, Y.1    Vecchiarelli-Federico, L.M.2    Li, Y.J.3    Egan, S.E.4    Spaner, D.5    Hough, M.R.6    Ben-David, Y.7
  • 91
    • 45849144168 scopus 로고    scopus 로고
    • Requirement of c-Myb for p210(BCR/ABL)-dependent transformation of hematopoietic progenitors and leukemogenesis
    • Lidonnici, M.R., Corradini, F., Waldron, T., Bender, T.P. & Calabretta, B. (2008) Requirement of c-Myb for p210(BCR/ABL)-dependent transformation of hematopoietic progenitors and leukemogenesis. Blood, 111, 4771-4779.
    • (2008) Blood , vol.111 , pp. 4771-4779
    • Lidonnici, M.R.1    Corradini, F.2    Waldron, T.3    Bender, T.P.4    Calabretta, B.5
  • 92
    • 22144478256 scopus 로고    scopus 로고
    • MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies
    • Liu, J., Valencia-Sanchez, M.A., Hannon, G.J. & Parker, R. (2005) MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies. Nature Cell Biology, 7, 719-723.
    • (2005) Nature Cell Biology , vol.7 , pp. 719-723
    • Liu, J.1    Valencia-Sanchez, M.A.2    Hannon, G.J.3    Parker, R.4
  • 96
    • 0025348013 scopus 로고
    • Tyrosine kinase activity and transformation potency of bcr-abl oncogene products
    • Lugo, T.G., Pendergast, A.M., Muller, A.J. & Witte, O.N. (1990) Tyrosine kinase activity and transformation potency of bcr-abl oncogene products. Science, 247, 1079-1082.
    • (1990) Science , vol.247 , pp. 1079-1082
    • Lugo, T.G.1    Pendergast, A.M.2    Muller, A.J.3    Witte, O.N.4
  • 101
    • 79952092487 scopus 로고    scopus 로고
    • Molecular genetics of adult acute myeloid leukemia: prognostic and therapeutic implications
    • Marcucci, G., Haferlach, T. & Döhner, H. (2011a) Molecular genetics of adult acute myeloid leukemia: prognostic and therapeutic implications. Journal of Clinical Oncology, 29, 475-486.
    • (2011) Journal of Clinical Oncology , vol.29 , pp. 475-486
    • Marcucci, G.1    Haferlach, T.2    Döhner, H.3
  • 102
    • 79251585937 scopus 로고    scopus 로고
    • The prognostic and functional role of microRNAs in acute myeloid leukemia
    • Marcucci, G., Mrózek, K., Radmacher, M.D., Garzon, R. & Bloomfield, C.D. (2011b) The prognostic and functional role of microRNAs in acute myeloid leukemia. Blood, 117, 1121-1129.
    • (2011) Blood , vol.117 , pp. 1121-1129
    • Marcucci, G.1    Mrózek, K.2    Radmacher, M.D.3    Garzon, R.4    Bloomfield, C.D.5
  • 120
    • 34447097693 scopus 로고    scopus 로고
    • Intronic microRNA precursors that bypass Drosha processing
    • Ruby, J.G., Jan, C.H. & Bartel, D.P. (2007) Intronic microRNA precursors that bypass Drosha processing. Nature, 448, 83-86.
    • (2007) Nature , vol.448 , pp. 83-86
    • Ruby, J.G.1    Jan, C.H.2    Bartel, D.P.3
  • 121
  • 133
    • 79955010455 scopus 로고    scopus 로고
    • MicroRNA fate upon targeting with anti-miRNA oligonucleotides as revealed by an improved Northern-blot-based method for miRNA detection
    • Torres, A.G., Fabani, M.M., Vigorito, E. & Gait, M.J. (2011) MicroRNA fate upon targeting with anti-miRNA oligonucleotides as revealed by an improved Northern-blot-based method for miRNA detection. RNA, 17, 933-943.
    • (2011) RNA , vol.17 , pp. 933-943
    • Torres, A.G.1    Fabani, M.M.2    Vigorito, E.3    Gait, M.J.4
  • 136
    • 41949111045 scopus 로고    scopus 로고
    • Acute promyelocytic leukemia: from highly fatal to highly curable
    • Wang, Z.Y. & Chen, Z. (2008) Acute promyelocytic leukemia: from highly fatal to highly curable. Blood, 111, 2505-2515.
    • (2008) Blood , vol.111 , pp. 2505-2515
    • Wang, Z.Y.1    Chen, Z.2
  • 137
    • 64149121172 scopus 로고    scopus 로고
    • MicroRNA-based therapeutics for cancer
    • Wang, V. & Wu, W. (2009) MicroRNA-based therapeutics for cancer. BioDrugs, 23, 15-23.
    • (2009) BioDrugs , vol.23 , pp. 15-23
    • Wang, V.1    Wu, W.2
  • 141
  • 142
    • 80052527459 scopus 로고    scopus 로고
    • Post-transcriptional generation of miRNA variants by multiple nucleotidyl transferases contributes to miRNA transcriptome complexity
    • Wyman, S.K., Knouf, E.C., Parkin, R.K., Fritz, B.R., Lin, D.W., Dennis, L.M., Krouse, M.A., Webster, P.J. & Tewari, M. (2011) Post-transcriptional generation of miRNA variants by multiple nucleotidyl transferases contributes to miRNA transcriptome complexity. Genome Research, 21, 1450-1461.
    • (2011) Genome Research , vol.21 , pp. 1450-1461
    • Wyman, S.K.1    Knouf, E.C.2    Parkin, R.K.3    Fritz, B.R.4    Lin, D.W.5    Dennis, L.M.6    Krouse, M.A.7    Webster, P.J.8    Tewari, M.9
  • 143
    • 34748837455 scopus 로고    scopus 로고
    • Systematic analysis of microRNA expression of RNA extracted from fresh frozen and formalin-fixed paraffin-embedded samples
    • Xi, Y., Nakajima, G., Gavin, E., Morris, C.G., Kudo, K., Hayashi, K. & Ju, J. (2007) Systematic analysis of microRNA expression of RNA extracted from fresh frozen and formalin-fixed paraffin-embedded samples. RNA, 13, 1668-1674.
    • (2007) RNA , vol.13 , pp. 1668-1674
    • Xi, Y.1    Nakajima, G.2    Gavin, E.3    Morris, C.G.4    Kudo, K.5    Hayashi, K.6    Ju, J.7
  • 144
    • 2142654329 scopus 로고    scopus 로고
    • MicroRNA-directed cleavage of HOXB8 mRNA
    • Yekta, S., Shih, I.H. & Bartel, D.P. (2004) MicroRNA-directed cleavage of HOXB8 mRNA. Science, 304, 594-596.
    • (2004) Science , vol.304 , pp. 594-596
    • Yekta, S.1    Shih, I.H.2    Bartel, D.P.3
  • 145
    • 0347361541 scopus 로고    scopus 로고
    • Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs
    • Yi, R., Qin, Y., Macara, I.G. & Cullen, B.R. (2003) Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes and Development, 17, 3011-3016.
    • (2003) Genes and Development , vol.17 , pp. 3011-3016
    • Yi, R.1    Qin, Y.2    Macara, I.G.3    Cullen, B.R.4
  • 146
    • 65549111789 scopus 로고    scopus 로고
    • Targeted delivery systems for oligonucleotide therapeutics
    • Yu, B., Zhao, X., Lee, L.J. & Lee, R.J. (2009) Targeted delivery systems for oligonucleotide therapeutics. The AAPS Journal, 11, 195-203.
    • (2009) The AAPS Journal , vol.11 , pp. 195-203
    • Yu, B.1    Zhao, X.2    Lee, L.J.3    Lee, R.J.4
  • 149
    • 80052169985 scopus 로고    scopus 로고
    • Upregulation of microRNA-125b contributes to leukemogenesis and increases drug resistance in pediatric acute promyelocytic leukemia
    • Zhang, H., Luo, X.Q., Feng, D.D., Zhang, X.J., Wu, J., Zheng, Y.S., Chen, X., Xu, L. & Chen, Y.Q. (2011) Upregulation of microRNA-125b contributes to leukemogenesis and increases drug resistance in pediatric acute promyelocytic leukemia. Molecular Cancer, 10, 108.
    • (2011) Molecular Cancer , vol.10 , pp. 108
    • Zhang, H.1    Luo, X.Q.2    Feng, D.D.3    Zhang, X.J.4    Wu, J.5    Zheng, Y.S.6    Chen, X.7    Xu, L.8    Chen, Y.Q.9
  • 150
    • 84871735114 scopus 로고    scopus 로고
    • Prognostic value of miR-29a expression in pediatric acute myeloid leukemia
    • Zhu, C., Wang, Y., Kuai, W., Sun, X., Chen, H. & Hong, Z. (2013) Prognostic value of miR-29a expression in pediatric acute myeloid leukemia. Clinical Biochemistry, 46, 49-53.
    • (2013) Clinical Biochemistry , vol.46 , pp. 49-53
    • Zhu, C.1    Wang, Y.2    Kuai, W.3    Sun, X.4    Chen, H.5    Hong, Z.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.