Changes in gene expression within the ventral tegmental area following repeated excessive binge-like alcohol drinking by alcohol-preferring (P) rats

Alcohol

Volumn 47, Issue 5, 2013, Pages 367-380

  McBride, William J ^a   Kimpel, Mark W ^a   McClintick, Jeanette N ^a   Ding, Zheng Ming ^a   Hauser, Sheketha R ^a   Edenberg, Howard J ^a   Bell, Richard L ^a   Rodd, Zachary A ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alcohol preferring rat; Binge like alcohol drinking; Gene expression; Ventral tegmental area

Indexed keywords

PROTEIN FOS; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TRANSCRIPTION FACTOR;

ALCOHOL BLOOD LEVEL; ALCOHOL CONSUMPTION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINGE DRINKING; BIOINFORMATICS; CHOLESTEROL SYNTHESIS; CONTROLLED STUDY; DOWN REGULATION; EXCITOTOXICITY; FATTY ACID SYNTHESIS; FEMALE; FOS GENE; GENE; GENE EXPRESSION; INFLAMMATION; NONHUMAN; NUCLEAR FACTOR OF KAPPA LIGHT POLYPEPTIDE GENE ENHANCER IN B CELLS INHIBITOR ALPHA; PROTEIN DEGRADATION; PROTEIN METABOLISM; RAT; STEROID METABOLISM; STEROL REGULATORY ELEMENT BINDING TRANSCRIPTION FACTOR 1 GENE; UPREGULATION; VENTRAL TEGMENTUM;

ALCOHOLISM; ANIMALS; BINGE DRINKING; FEMALE; GENE EXPRESSION REGULATION; RATS; RATS, INBRED STRAINS; VENTRAL TEGMENTAL AREA;

RATTUS;

EID: 84879781638     PISSN: 07418329     EISSN: 18736823     Source Type: Journal    
DOI: 10.1016/j.alcohol.2013.04.002     Document Type: Article

References (77)

1. Alexander-Kaufman K., Harper C., Wilce P., Matsumoto I. Cerebellar vermis proteome of chronic alcoholic individuals. Alcoholism: Clinical and Experimental Research 2007, 31:1286-1296.
2. Alexander-Kaufman K., James G., Sheedy D., Harper C., Matsumoto I. Differential protein expression in the prefrontal white matter of human alcoholics: a proteomics study. Molecular Psychiatry 2006, 11:56-65.
3. Ashburner M., Ball C.A., Blake J.A., Botstein D., Butler H., Cherry J.M., et al. Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nature Genetics 2000, 25:25-29.
4. Bell R.L., Kimpel M.W., McClintick J.N., Strother W.N., Carr L.G., Liang T., et al. Gene expression changes in the nucleus accumbens of alcohol-preferring rats following chronic ethanol consumption. Pharmacology Biochemistry & Behavior 2009, 94:131-147.
5. Bell R.L., Kimpel M.W., Rodd Z.A., Strother W.N., Bai F., Peper C.L., et al. Protein expression changes in the nucleus accumbens and amygdala of inbred alcohol-preferring rats given either continuous or scheduled access to ethanol. Alcohol 2006, 40:3-17.
6. Bice P.J., Liang T., Zhang L., Graves T.J., Carr L.G., Lai D., et al. Fine mapping and expression of candidate genes within the chromosome 10 QTL region of the high and low alcohol-drinking rats. Alcohol 2010, 44:477-485.
7. Cahoy J.D., Emery B., Kaushal A., Foo L.C., Zamanian J.L., Christopherson K.S., et al. Atranscriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function. Journal of Neuroscience 2008, 28:264-278.
8. Carr L.G., Kimpel M.W., Liang T., McClintick J.N., McCall K., Morse M., et al. Identification of candidate genes for alcohol preference by expression profiling of congenic rat strains. Alcoholism: Clinical and Experimental Research 2007, 31:1089-1098.
9. Carter C.J. Convergence of genes implicated in Alzheimer's disease on the cerebral cholesterol shuttle: APP, cholesterol, lipoproteins, and atherosclerosis. Neurochemistry International 2007, 50:12-38.
10. Crews F.T., Qin L., Sheedy D., Vetreno R.P., Zou J. High mobility group box 1/toll-like receptor danger signaling increases brain neuroimmune activation in alcohol dependence. Biological Psychiatry 2013, 73:602-612.
11. Cuajungco M.P., Podevin W., Valluri V.K., Bui Q., Nguyen V.H., Taylor K. Abnormal accumulation of human transmembrane (TMEM)-176A and 176B proteins is associated with cancer pathology. Acta Histochemica 2012, 114:705-712.
12. D'Adamio F., Zollo O., Moraca R., Ayroldi E., Bruscoli S., Bartoli A., et al. Anew dexamethasone-induced gene of the leucine zipper family protects T lymphocytes from TCR/CD3-activated cell death. Immunity 1997, 7:803-812.
13. Dandoy-Dron F., Griffond B., Mishal Z., Tovey M.G., Dron M. Scrg1, a novel protein of the CNS, is targeted to the large dense-core vesicles in neuronal cells. European Journal of Neuroscience 2003, 18:2449-2459.
14. Ding Z.-M., Rodd Z.A., Engleman E.A., McBride W.J. Sensitization of ventral tegmental area dopamine neurons to the stimulating effects of ethanol. Alcoholism: Clinical and Experimental Research 2009, 33:1571-1581.
15. Edenberg H.J., Strother W.N., McClintick J.N., Tian H., Stephans M., Jerome R.E., et al. Gene expression in the hippocampus of inbred alcohol-preferring and -nonpreferring rats. Genes, Brain and Behavior 2005, 4:20-30.
16. Flatscher-Bader T., Harrison E., Matsumoto I., Wilce P.A. Genes associated with alcohol abuse and tobacco smoking in the human nucleus accumbens and ventral tegmental area. Alcoholism: Clinical and Experimental Research 2010, 34:1291-1302.
17. Flatscher-Bader T., van der Brug M., Hwang J.W., Gochee P.A., Matsumoto I., Niwa S., et al. Alcohol-responsive genes in the frontal cortex and nucleus accumbens of human alcoholics. Journal of Neurochemistry 2005, 93:359-370.
18. Flatscher-Bader T., Zuvela N., Landis N., Wilce P.A. Smoking and alcoholism target genes associated with plasticity and glutamate transmission in the human ventral tegmental area. Human Molecular Genetics 2008, 17:38-51.
19. Gatto G.J., McBride W.J., Murphy J.M., Lumeng L., Li T.-K. Ethanol self-infusion into the ventral tegmental area by alcohol-preferring rats. Alcohol 1994, 11:557-564.
20. Gentleman, R. C. (2004). Using GO for statistical analysis. Proceedings in Computational Statistics-COMPSTAT 2004, 171-180.
21. Gentleman R.C., Carey V.J., Bates D.M., Bolstad B., Dettling M., Dudoit S., et al. Bioconductor: open software development for computational biology and bioinformatics. Genome Biology 2004, 5:R80.
22. George O., Sanders C., Freiling J., Grigoryan E., Vu S., Allen C.D., et al. Recruitment of medial prefrontal cortex neurons during alcohol withdrawal predicts cognitive impairment and excessive alcohol drinking. Proceedings of theNational Academy of Sciences of the United States of America 2012, 109:18156-18161.
23. Harris M.A., Clark J., Ireland A., Lomax J., Ashburner M., Foulger R., et al. The Gene Ontology (GO) database and informatics resource. Nucleic Acids Research 2004, 32:D258-D261. Database issue.
24. Harris G.J., Jaffin S.K., Hodge S.M., Kennedy D., Caviness V.S., Marinkovic K., et al. Frontal white matter and cingulum diffusion tensor imaging deficits in alcoholism. Alcoholism: Clinical and Experimental Research 2008, 32:1001-1013.
25. Hauser S.R., Ding Z.-M., Getachew B., Toalston J.E., Oster S.M., McBride W.J., et al. The posterior ventral tegmental area mediates alcohol-seeking behavior in alcohol-preferring rats. Journal of Pharmacology and Experimental Therapeutics 2011, 336:857-865.
26. He M., Kratz L.E., Michel J.J., Vallejo A.N., Ferris L., Kelley R.I., et al. Mutations in the human SC4MOL gene encoding a methyl sterol oxidase cause psoriasiform dermatitis, microcephaly, and developmental delay. Journal of Clinical Investigation 2011, 121:976-984.
27. Himadri P., Kumari S.S., Chitharanjan S., Dhananjay S. Role of oxidative stress and inflammation in hypoxia-induced cerebral edema: a molecular approach. High Altitude Medicine & Biology 2010, 11:231-244.
28. Hodge C.W., Haraguchi M., Erickson H., Samson H.H. Ventral tegmental microinjections of quinpirole decrease ethanol and sucrose-reinforced responding. Alcoholism: Clinical and Experimental Research 1993, 17:370-375.
29. Hou H.F., Liang Y.H., Li L.F., Su X.D., Dong Y.H. Crystal structures of Streptococcus mutans 2'-desoxycytidylate deaminase and its complex with substrate analog and allosteric regulator dCTP x Mg2+. Journal of Molecular Biology 2008, 377:220-231.
30. Hwa L.S., Debold J.F., Miczek K.A. Alcohol in excess: CRF (1) receptors in the rat and mouse VTA and DRN. Psychopharmacology 2013, 225:313-327.
31. Irizarry R.A., Hobbs B., Collin F., Beazer-Barclay Y.D., Antonellis K.J., Scherf U., et al. Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics 2003, 4:249-264.
32. Katoh M., Katoh M. Identification and characterization of ARHGAP24 and ARHGAP25 genes in silico. International Journal of Molecular Medicine 2004, 14:333-338.
33. Kerns R.T., Ravindranathan A., Hassan S., Cage M.P., York T., Sikela J.M., et al. Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. Journal of Neuroscience 2005, 25:2255-2266.
34. Kimpel M.W., Strother W.N., McClintick J.N., Carr L.G., Edenberg H.J., McBride W.J. Functional gene expression differences between inbred alcohol-preferring (iP) and -non-preferring (iNP) rats in five brain regions. Alcohol 2007, 41:95-132.
35. Koltsova S.V., Truchina Y., Haloui M., Akimova O.A., Tremblay J., Harnet P., et al. Unbiquitous [Na+]i/[K+]i-sensitive transcriptome in mammalian cells: evidence for Ca(2+)i-independent excitation-transcription coupling. PloS One 2012, 7:e38032.
36. Korostynski M., Piechota M., Kaminska D., Solecki W., Przewlocki R. Morphine effects on striatal transcriptome in mice. Genome Biology 2007, 8:R128.
37. Langfelder P., Horvath S. WGCNA: an R package for weighted correlation network analysis. BMC Bioinformatics 2008, 9:559.
38. Langfelder P., Horvath S. Fast R functions for robust correlations and hierarchical clustering. Journal of Statistical Software 2012, 46.
39. Larson K.C., Lipko M., Dabrowski M., Draper M.P. Gng12 is a novel negative regulator of LPS-induced inflammation in the microglial cell line BV-2. Inflammation Research 2010, 59. Epub 01.07.09.
40. Lewohl J.M., Van Dyk D.D., Craft G.E., Innes D.J., Mayfield R.D., Cobon G., et al. The application of proteomics to the human alcoholic brain. Annals of the New York Academy of Sciences 2004, 1025:14-26.
41. Lewohl J.M., Wang L., Miles M.F., Zhang L., Dodd P.R., Harris R.A. Gene expression in human alcoholism: microarray analysis of frontal cortex. Alcoholism: Clinical and Experimental Research 2000, 24:1873-1882.
42. Liu J., Lewohl J.M., Dodd P.R., Randall P.K., Harris R.A., Mayfield R.D. Gene expression profiling of individual cases reveals consistent transcriptional changes in alcoholic human brain. Journal of Neurochemistry 2004, 90:1050-1058.
43. Liu J., Lewohl J.M., Harris R.A., Iyer V.R., Dodd P.R., Randall P.K., et al. Patterns of gene expression in the frontal cortex discriminate alcoholic from nonalcoholic individuals. Neuropsychopharmacology 2006, 31:1574-1582.
44. Matsumoto I., Alexander-Kaufman K., Iwazaki T., Kashem M.A., Matsuda-Matsumoto H. CNS proteomes in alcohol and drug abuse and dependence. Expert Review of Proteomics 2007, 4:539-552.
45. Mayfield R.D., Lewohl J.M., Dodd P.R., Herlihy A., Liu J., Harris R.A. Patterns of gene expression are altered in the frontal and motor cortices of human alcoholics. Journal of Neurochemistry 2002, 81:802-813.
46. McBride W.J., Kimpel M.W., McClintick J.N., Ding Z.-M., Hyytia P., Colombo G., et al. Gene expression in the ventral tegmental area of 5 pairs of rat lines selectively bred for high or low ethanol consumption. Pharmacology Biochemistry & Behavior 2012, 102:275-285.
47. McBride W.J., Kimpel M.W., Schultz J.A., McClintick J.N., Edenberg H.J., Bell R.L. Changes in gene expression in regions of the extended amygdala of alcohol-preferring rats after binge-like alcohol drinking. Alcohol 2010, 44:171-183.
48. McBride W.J., Murphy J.M., Ikemoto S. Localization of brain reinforcement mechanism: intracranial self-administration and intracranial place-conditioning studies. Behavioural Brain Research 1999, 101:129-152.
49. McClintick J.N., Edenberg H.J. Effects of filtering by present call on analysis of microarray experiments. BMC Bioinformatics 2006, 7:49.
50. McClintick J.N., Jerome R.E., Nicholson C.R., Crabb D.W., Edenberg H.J. Reproducibility of oligonucleotide arrays using small samples. BMC Genomics 2003, 4:1-15.
51. Morel F., Aninat C. The glutathione transferase kappa family. Drug Metabolism Reviews 2011, 43:281-291.
52. Mulligan M.K., Ponomerav I., Hitzemann R.J., Belknap J.K., Tabakoff B., Harris R.A., et al. Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis. Proceedings of the National Academy of Sciences of the United States of America 2006, 103:6368-6373.
53. Mulligan M.K., Rhodes J.S., Crabbe J.C., Mayfield R.D., Harris R.A., Ponomarev I. Molecular profiles of drinking alcohol to intoxication in C57BL/6J mice. Alcoholism: Clinical and Experimental Research 2011, 35:659-670.
54. Ong W.Y., Hu C.Y., Soh Y.P., Lim T.M., Pentchev P.G., Patel S.C. Neuronal localization of sterol regulatory element binding protein-1 in the rodent and primate brain: a light and electron microscopic immunocytochemical study. Neuroscience 2000, 97:143-153.
55. Paxinos G., Watson C. The rat brain in stereotaxic coordinates 1998, Academic Press, New York.
56. Rodd Z.A., Bell R.L., McQueen V.K., Davids M.R., Hsu C.C., Murphy J.M., et al. Chronic alcohol drinking by alcohol-preferring rats increases the sensitivity of the posterior ventral tegmental area to the reinforcing effects of ethanol. Alcoholism: Clinical and Experimental Research 2005, 29:358-366.
57. Rodd Z.A., Bell R.L., McQueen V.K., Davids M.R., Hsu C.C., Murphy J.M., et al. Prolonged increases in the sensitivity of the posterior ventral tegmental area to the reinforcing effects of ethanol following repeated exposure to cycles of ethanol access and deprivation. Journal of Pharmacology and Experimental Therapeutics 2005, 315:648-657.
58. Rodd Z.A., Bell R.L., Melendez R.I., Kuc K.A., Lumeng L., Li T.-K., et al. Comparison of intracranial self-administration of ethanol within the posterior ventral tegmental area between alcohol-preferring and Wistar rats. Alcoholism: Clinical and Experimental Research 2004, 28:1212-1219.
59. Rodd Z.A., Bell R.L., Oster S.M., Toalston J.E., Pommer T.J., McBride W.J., et al. Serotonin-3 receptors in the posterior ventral tegmental area regulate ethanol self-administration of alcohol-preferring (P) rats. Alcohol 2010, 44:245-255.
60. Rodd Z.A., Kimpel M.W., Edenberg H.J., Bell R.L., Strother W.N., McClintick J.N., et al. Differential gene expression in the nucleus accumbens with ethanol self-administration in inbred alcohol-preferring rats. Pharmacology Biochemistry & Behavior 2008, 89:481-498.
61. Rodd-Henricks Z.A., Bell R.L., Kuc K.A., Murphy J.M., McBride W.J., Lumeng L., et al. Effects of ethanol exposure on subsequent acquisition and extinction of ethanol self-administration and expression of alcohol-seeking behavior in adult alcohol-preferring (P) rats: I. Peri-adolescent exposure. Alcoholism: Clinical and Experimental Research 2002, 26:1632-1641.
62. Rodd-Henricks Z.A., Bell R.L., Kuc K.A., Murphy J.M., McBride W.J., Lumeng L., et al. Effects of ethanol exposure on subsequent acquisition and extinction of ethanol self-administration and expression of alcohol-seeking behavior in adult alcohol-preferring (P) rats: I. Adult exposure. Alcoholism: Clinical and Experimental Research 2002, 26:1642-1652.
63. Rodd-Henricks Z.A., McKinzie D.L., Crile R.S., Murphy J.M., McBride W.J. Regional heterogeneity for the intracranial self-administration of ethanol within the ventral tegmental area of female Wistar rats. Psychopharmacology 2000, 149:217-224.
64. Saito M., Smiley J., Toth R., Vadasz C. Microarray analysis of gene expression in rat hippocampus after chronic ethanol treatment. Neurochemical Research 2002, 27:1221-1229.
65. Saito M., Szakall I., Toth R., Kovacs K.M., Oros M., Prasad V.V., et al. Mouse striatal transcriptome analysis: effects of oral self-administration of alcohol. Alcohol 2004, 32:223-241.
66. Scheinman R.I., Cogswell P.C., Lofquist A.K., Baldwin A.S. Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids. Science 1995, 270:283-286.
67. Schiavone D., Avalle L., Dewilde S., Poli V. The immediate early genes Fos and Egr1 become STAT1 transcriptional targets in the absence of STAT3. FEBS Letters 2011, 585:2455-2460.
68. Simon J.A., Lange C.A. Roles of the EZH2 histone methyltransferase in cancer epigenetics. Mutation Research 2008, 647:21-29.
69. Smyth G.K. Linear models and empirical Bayes methods for assessing differential expression in microarray experiments. Statistical Applications in Genetics and Molecular Biology 2004, 3. article 3.
70. Stephan A.H., Barres B.A., Stevens B. The complement system: an unexpected role in synaptic pruning during development and disease. Annual Review of Neuroscience 2012, 35:369-389.
71. Storey J.D., Taylor J.E., Siegmund D. Strong control, conservative point estimation, and simultaneous conservative consistency of false discovery rates: a unified approach. Journal of the Royal Statistical Society: Series B 2004, 66:187-205.
72. Tabakoff B., Saba L., Printz M., Flodman P., Hodgkinson C., Goldman D., et al. Genetical genomic determinants of alcohol consumption in rats and humans. BMC Biology 2009, 7:70-78.
73. Tabernero A., Velasco A., Granda B., Lavado E.M., Medina J.M. Transcytosis of albumin in astrocytes activates the sterol regulatory element-binding protein-1, which promotes the synthesis of the neurotrophic factor oleic acid. Journal of Biological Chemistry 2002, 277:4240-4246.
74. Treadwell J.A., Singh S.M. Microarray analysis of mouse brain gene expression following acute ethanol treatment. Neurochemical Research 2004, 29:357-369.
75. Xiang Z., Valenza M., Cui L., Leoni V., Jeong H.-K., Brilli E., et al. Peroxisome-proliferator-activated receptor gamma coactivator 1 alpha contributes to dysmyelination in experimental models of Huntington's disease. Journal of Neuroscience 2011, 31:9544-9553.
76. Yu D., Cook M.C., Shin D.M., Silva D.G., Marshall J., Toellner K.M., et al. Axon growth and guidance genes identify T-dependent germinal centre B cells. Immunology and Cell Biology 2008, 86:3-14.
77. Zhang B., Horvath S. Ageneral framework for weighted gene co-expression network analysis. Statistical Applications in Genetics and Molecular Biology 2005, 4. article 17.