Frontal white matter and cingulum diffusion tensor imaging deficits in alcoholism

Alcoholism: Clinical and Experimental Research

Volumn 32, Issue 6, 2008, Pages 1001-1013

  Harris, Gordon J ^a   Jaffin, Sharon Kim ^a   Hodge, Steven M ^a   Kennedy, David ^a   Caviness, Verne S ^a   Marinkovic, Ksenija ^a   Papadimitriou, George M ^a   Makris, Nikos ^a,b   Oscar Berman, Marlene ^b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alcoholism; Diffusion Tensor Magnetic Resonance Imaging; Reward System; Right Hemisphere; White Matter

Indexed keywords

ADULT; AGED; ALCOHOLISM; ANISOTROPY; ARTICLE; BRAIN DYSFUNCTION; CINGULATE GYRUS; CLINICAL ARTICLE; DIFFUSION TENSOR IMAGING; EMOTIONAL DISORDER; FRONTAL LOBE; HUMAN; MALE; MEMORY DISORDER; NEUROPSYCHOLOGICAL TEST; PERCEPTIVE DISCRIMINATION; PRIORITY JOURNAL; REWARD; RIGHT HEMISPHERE; WHITE MATTER; WORKING MEMORY;

ADULT; AGED; ALCOHOLISM; ANISOTROPY; DIFFUSION MAGNETIC RESONANCE IMAGING; EMOTIONS; FRONTAL LOBE; FUNCTIONAL LATERALITY; GYRUS CINGULI; HUMANS; LIMBIC SYSTEM; MALE; MEMORY; MIDDLE AGED; REWARD;

EID: 44349119143     PISSN: 01456008     EISSN: 15300277     Source Type: Journal    
DOI: 10.1111/j.1530-0277.2008.00661.x     Document Type: Article

References (107)

1. Abi-Dargham A, Krystal JH, Anjilvel S, Scanley BE, Zoghbi S, Baldwin RM, Rajeevan N, Ellis S, Petrakis IL, Seibyl JP, Charney DS, Laruelle M, Innis RB (1998) Alterations of benzodiazepine receptors in type II alcoholic subjects measured with SPECT and [123I]iomazenil. Am J Psychiatry 155 : 1550 1555.
2. APA (1994) Diagnostic and Statistical Manual of Mental Disorders (DSM-IV). American Psychiatric Association, Washington, DC.
3. Baker TB, Piper ME, McCarthy DE, Majeskie MR, Fiore MC (2004) Addiction motivation reformulated: an affective processing model of negative reinforcement. Psychol Rev 111 : 33 51.
4. Basser PJ, Mattiello J, LeBihan D (1994) Estimation of the effective self-diffusion tensor from the NMR spin echo. J Magn Reson B 103 : 247 254.
5. Berg EA (1948) A simple objective technique for measuring flexibility in thinking. J Gen Psychol 39 : 15 22.
6. Blum K, Braverman ER, Holder JM, Lubar JF, Monastra VJ, Miller D, Lubar JO, Chen TJ, Comings DE (2000) Reward deficiency syndrome: a biogenetic model for the diagnosis and treatment of impulsive, addictive, and compulsive behaviors. J Psychoactive Drugs 32 (Suppl. i-iv 1 112.
7. Bowirrat A, Oscar-Berman M (2005) Relationship between dopaminergic neurotransmission, alcoholism, and Reward Deficiency Syndrome. Am J Med Genet B Neuropsychiatr Genet 132 : 29 37.
8. Briggs GG, Nebes RD (1975) Patterns of hand preference in a student population. Cortex 11 : 230 238.
9. Cahalan V, Cisin I, Crossley HM (1969) American Drinking Practices: A National Study of Drinking Behavior and Attitudes, Report 6. Rutgers Center for Alcohol Studies, New Brunswick, NJ.
10. Caviness VS Jr., Meyer JW, Makris N, Kennedy DN (1996) MRI-based topographic parcellation of the human neocortex: an anatomically specified method with estimate of reliability. J Cogn Neurosci 8 : 566 587.
11. Comings DE, Blum K (2000) Reward deficiency syndrome: genetic aspects of behavioral disorders. Prog Brain Res 126 : 325 341.
12. Crews FT, Buckley T, Dodd PR, Ende G, Foley N, Harper C, He J, Innes D, Lohel W, Pfefferbaum A, Zou J, Sullivan EV (2005) Alcoholic neurobiology: changes in dependence and recovery. Alcohol Clin Exp Res 29 : 1504 1513.
13. Davis KD, Taylor KS, Hutchison WD, Dostrovsky JO, McAndrews MP, Richter EO, Lozano AM (2005) Human anterior cingulate cortex neurons encode cognitive and emotional demands. J Neurosci 25 : 8402 8406.
14. Demaree HA, Everhart DE, Youngstrom EA, Harrison DW (2005) Brain lateralization of emotional processing: historical roots and a future incorporating "dominance". Behav Cogn Neurosci Rev 4 : 3 20.
15. Desmond JE, Chen SH, DeRosa E, Pryor MR, Pfefferbaum A, Sullivan EV (2003) Increased frontocerebellar activation in alcoholics during verbal working memory: an fMRI study. Neuroimage 19 : 1510 1520.
16. Elliott R, Newman JL, Longe OA, Deakin JF (2003) Differential response patterns in the striatum and orbitofrontal cortex to financial reward in humans: a parametric functional magnetic resonance imaging study. J Neurosci 23 : 303 307.
17. Ellis RJ, Oscar-Berman M (1989) Alcoholism, aging, and functional cerebral asymmetries. Psychol Bull 106 : 128 147.
18. Estruch R, Nicolas JM, Salamero M, Aragon C, Sacanella E, Fernandez-Sola J, Urbano-Marquez A (1997) Atrophy of the corpus callosum in chronic alcoholism. J Neurol Sci 146 : 145 151.
19. Flatscher-Bader T, van der Brug M, Hwang JW, Gochee PA, Matsumoto I, Niwa S, Wilce PA (2005) Alcohol-responsive genes in the frontal cortex and nucleus accumbens of human alcoholics. J Neurochem 93 : 359 370.
20. Fuster JM (2003) Cortex and Mind. Oxford University Press, New York.
21. Goldstein RZ, Volkow ND (2002) Drug addiction and its underlying neurobiological basis: neuroimaging evidence for the involvement of the frontal cortex. Am J Psychiatry 159 : 1642 1652.
22. Grant DA, Berg EA (1948) A behavioral analysis of degree of reinforcement and ease of shifting to new responses in a Weigl-type card-sorting problem. J Exp Psychol 38 : 404 411.
23. Grusser SM, Wrase J, Klein S, Hermann D, Smolka MN, Ruf M, Weber-Fahr W, Flor H, Mann K, Braus DF, Heinz A (2004) Cue-induced activation of the striatum and medial prefrontal cortex is associated with subsequent relapse in abstinent alcoholics. Psychopharmacology 175 : 296 302.
24. Ham HP, Parsons OA (1997) Organization of psychological functions in alcoholics and nonalcoholics: a test of the compensatory hypothesis. J Stud Alcohol 58 : 67 74.
25. Hamilton MA (1960) A rating scale for depression. J Neurol Neurosurg Psychiatry 23 : 56 62.
26. Harper C, Dixon G, Sheedy D, Garrick T (2003) Neuropathological alterations in alcoholic brains. Studies arising from the New South Wales Tissue Resource Centre. Prog Neuropsychopharmacol Biol Psychiatry 27 : 951 961.
27. Harper C, Kril J, Daly J (1987) Are we drinking our neurones away? Br Med J (Clin Res Ed) 294 : 534 536.
28. Heaton R, Chelune G, Talley J, Kay G, Curtis G (1993) Wisconsin Card Sorting Test: Computer Version 4. Psychological Assessment Resources Inc., Lutz, FL.
29. Heimer L, Van Hoesen GW (2006) The limbic lobe and its output channels: implications for emotional functions and adaptive behavior. Neurosci Biobehav Rev 30 : 126 147.
30. Heinz A, Siessmeier T, Wrase J, Hermann D, Klein S, Grusser SM, Flor H, Braus DF, Buchholz HG, Grunder G, Schreckenberger M, Smolka MN, Rosch F, Mann K, Bartenstein P (2004) Correlation between dopamine D(2) receptors in the ventral striatum and central processing of alcohol cues and craving. Am J Psychiatry 161 : 1783 1789.
31. Hommer DW (2003) Male and female sensitivity to alcohol-induced brain damage. Alcohol Res Health 27 : 181 185.
32. Hornak J, Rolls ET, Wade D (1996) Face and voice expression identification in patients with emotional and behavioural changes following ventral frontal lobe damage. Neuropsychologia 34 : 247 261.
33. Hutner N, Oscar-Berman M (1996) Visual laterality patterns for the perception of emotional words in alcoholic and aging individuals. J Stud Alcohol 57 : 144 154.
34. Jenkinson M, Bannister P, Brady M, Smith S (2002) Improved optimization for the robust and accurate linear registration and motion correction of brain images. Neuroimage 17 : 825 841.
35. Jenkinson M, Smith S (2001) A global optimisation method for robust affine registration of brain images. Med Image Anal 5 : 143 156.
36. Kornreich C, Blairy S, Philippot P, Hess U, Noel X, Streel E, Le Bon O, Dan B, Pelc I, Verbanck P (2001) Deficits in recognition of emotional facial expression are still present in alcoholics after mid- to long-term abstinence. J Stud Alcohol 62 : 533 542.
37. Lewohl JM, Wang L, Miles MF, Zhang L, Dodd PR, Harris RA (2000) Gene expression in human alcoholism: microarray analysis of frontal cortex. Alcohol Clin Exp Res 24 : 1873 1882.
38. MacVane J, Butters N, Montgomery K, Farber J (1982) Cognitive functioning in men social drinkers; a replication study. J Stud Alcohol 43 : 81 95.
39. Madden DJ, Whiting WL, Huettel SA, White LE, MacFall JR, Provenzale JM (2004) Diffusion tensor imaging of adult age differences in cerebral white matter: relation to response time. Neuroimage 21 : 1174 1181.
40. Makris N, Kennedy DN, McInerney S, Sorensen AG, Wang R, Caviness VS Jr., Pandya DN (2005) Segmentation of subcomponents within the superior longitudinal fascicle in humans: a quantitative, in vivo, DT-MRI study. Cereb Cortex 15 : 854 869.
41. Makris N, Meyer JW, Bates JF, Yeterian EH, Kennedy DN, Caviness VS (1999) MRI-Based topographic parcellation of human cerebral white matter and nuclei II. Rationale and applications with systematics of cerebral connectivity. Neuroimage 9 : 18 45.
42. Makris N, Oscar-Berman M, Kim SE, Hodge SM, Kennedy DN, Caviness VS, Marinkovic K, Breiter HC, Gasic GP, Harris GJ (2008) Decreased volume of the brain reward system in alcoholism. Biol Psychiatry (In press).
43. Makris N, Pandya DN, Normandin JJ (2002a) Quantitative DT-MRI investigations of the human cingulum bundle. Cent Nerv Sys Spectrums 7 : 522 528.
44. Makris N, Papadimitriou GM, Worth AJ, Jenkins BG, Garrido L, Sorensen AG, Wedeen V, Tuch DS, Wu O, Cudkowicz ME, Caviness VS Jr., Rosen B, Kennedy DN (2002b) Diffusion tensor imaging, in Neuropsychopharmacology: The Fifth Generation of Progress (Davis KL, Charney D, Coyle J, Nemeroff C eds pp 357 371. Lippincott, Williams, and Wilkins, New York.
45. Mantere T, Tupala E, Hall H, Sarkioja T, Rasanen P, Bergstrom K, Callaway J, Tiihonen J (2002) Serotonin transporter distribution and density in the cerebral cortex of alcoholic and nonalcoholic comparison subjects: a whole-hemisphere autoradiography study. Am J Psychiatry 159 : 599 606.
46. McNair DM, Lorr M, Droppleman LF (1981) Manual for the Profile of Mood States. Educational and Industrial Testing Service, San Diego, CA.
47. Morgane PJ, Galler JR, Mokler DJ (2005) A review of systems and networks of the limbic forebrain/limbic midbrain. Prog Neurobiol 75 : 143 160.
48. Moselhy HF, Georgiou G, Kahn A (2001) Frontal lobe changes in alcoholism: a review of the literature. Alcohol Alcohol 36 : 357 368.
49. Mufson EJ, Pandya DN (1984) Some observations on the course and composition of the cingulum bundle in the rhesus monkey. J Comp Neurol 225 : 31 43.
50. Mukamal KJ (2004) Alcohol consumption and abnormalities of brain structure and vasculature. Am J Geriatr Cardiol 13 : 22 28.
51. Myrick H, Anton RF, Li X, Henderson S, Drobes D, Voronin K, George MS (2004) Differential brain activity in alcoholics and social drinkers to alcohol cues: relationship to craving. Neuropsychopharmacology 29 : 393 402.
52. O'Doherty JP (2004) Reward representations and reward-related learning in the human brain: insights from neuroimaging. Curr Opin Neurobiol 14 : 769 776.
53. O'Neill J, Cardenas VA, Meyerhoff DJ (2001) Effects of abstinence on the brain: quantitative magnetic resonance imaging and magnetic resonance spectroscopic imaging in chronic alcohol abuse. Alcohol Clin Exp Res 25 : 1673 1682.
54. Oscar-Berman M, Bowirrat A (2005) Genetic influences in emotional dysfunction and alcoholism-related brain damage. Neuropsychiatr Dis Treat 1 : 211 229.
55. Oscar-Berman M, Marinkovic K (2003) Alcoholism and the brain: an overview. Alcohol Res Health 27 : 125 133.
56. Oscar-Berman M, Marinkovic K (2007) Alcohol: effects on neurobehavioral functions and the brain. Neuropsychol Rev 17 : 239 257.
57. Oscar-Berman M, Schendan HE (2000) Asymmetries of brain function in alcoholism: relationship to aging, in Neurobehavior of Language and Cognition: Studies of Normal Aging and Brain Damage (Obler L, Connor LT eds pp 213 240. Kluwer Academic Publishers, New York.
58. Paula-Barbosa MM, Tavares MA (1985) Long term alcohol consumption induces microtubular changes in the adult rat cerebellar cortex. Brain Res 339 : 195 199.
59. Pentney RJ (1991) Remodeling of neuronal dendritic networks with aging and alcohol. Alcohol Alcohol Suppl 1 : 393 397.
60. Petrides M (2005) Lateral prefrontal cortex: architectonic and functional organization. Philos Trans R Soc Lond B Biol Sci 360 : 781 795.
61. Petrides M, Pandya DN (1988) Association fiber pathways to the frontal cortex from the superior temporal region in the rhesus monkey. J Comp Neurol 273 : 52 66.
62. Petrides M, Pandya DN (2002) Association pathways of the prefrontal cortex and functional observations, in Principles of Frontal Lobe Function (Stuss DT, Knight RT eds pp 31 50. Oxford University Press, New York.
63. Pfefferbaum A, Adalsteinsson E, Sullivan EV (2005) Frontal circuitry degradation marks healthy adult aging: evidence from diffusion tensor imaging. Neuroimage 26 : 891 899.
64. Pfefferbaum A, Adalsteinsson E, Sullivan EV (2006) Supratentorial profile of white matter microstructural integrity in recovering alcoholic men and women. Biol Psychiatry 59 : 364 372.
65. Pfefferbaum A, Desmond JE, Galloway C, Menon V, Glover GH, Sullivan EV (2001a) Reorganization of frontal systems used by alcoholics for spatial working memory: an fMRI study. Neuroimage 14 : 7 20.
66. Pfefferbaum A, Lim KO, Desmond JE, Sullivan EV (1996) Thinning of the corpus callosum in older alcoholic men: a magnetic resonance imaging study. Alcohol Clin Exp Res 20 : 752 757.
67. Pfefferbaum A, Lim KO, Zipursky RB, Mathalon DH, Rosenbloom MJ, Lane B, Ha CN, Sullivan EV (1992) Brain gray and white matter volume loss accelerates with aging in chronic alcoholics: a quantitative MRI study. Alcohol Clin Exp Res 16 : 1078 1089.
68. Pfefferbaum A, Rosenbloom MJ, Adalsteinsson E, Sullivan EV (2007) Diffusion tensor imaging with quantitative fibre tracking in HIV infection and alcoholism comorbidity: synergistic white matter damage. Brain 130 (Pt. 1 48 64.
69. Pfefferbaum A, Rosenbloom M, Deshmukh A, Sullivan E (2001b) Sex differences in the effects of alcohol on brain structure. Am J Psychiatry 158 : 188 197.
70. Pfefferbaum A, Sullivan EV (2002) Microstructural but not macrostructural disruption of white matter in women with chronic alcoholism. Neuroimage 15 : 708 718.
71. Pfefferbaum A, Sullivan EV (2003) Increased brain white matter diffusivity in normal adult aging: relationship to anisotropy and partial voluming. Magn Reson Med 49 : 953 961.
72. Pfefferbaum A, Sullivan EV (2005) Disruption of brain white matter microstructure by excessive intracellular and extracellular fluid in alcoholism: evidence from diffusion tensor imaging. Neuropsychopharmacology 30 : 423 432.
73. Pfefferbaum A, Sullivan EV, Hedehus M, Adalsteinsson E, Lim KO, Moseley M (2000) In vivo detection and functional correlates of white matter microstructural disruption in chronic alcoholism. Alcohol Clin Exp Res 24 : 1214 1221.
74. Pfefferbaum A, Sullivan EV, Mathalon DH, Lim KO (1997) Frontal lobe volume loss observed with magnetic resonance imaging in older chronic alcoholics. Alcohol Clin Exp Res 21 : 521 529.
75. Pfefferbaum A, Sullivan EV, Mathalon DH, Shear PK, Rosenbloom MJ, Lim KO (1995) Longitudinal changes in magnetic resonance imaging brain volumes in abstinent and relapsed alcoholics. Alcohol Clin Exp Res 19 : 1177 1191.
76. Pierpaoli C (2002) Inferring structural and architectural features of brain tissue from DT-MRI measurements. CNS Spectrums 7 : 510 515.
77. Pierpaoli C, Basser PJ (1996) Toward a quantitative assessment of diffusion anisotropy. Magn Reson Med 36 : 893 906.
78. Prendergast MA (2004) Do women possess a unique susceptibility to the neurotoxic effects of alcohol? J Am Med Womens Assoc 59 : 225 227.
79. Putzke J, De Beun R, Schreiber R, De Vry J, Tolle TR, Zieglgansberger W, Spanagel R (1998) Long-term alcohol self-administration and alcohol withdrawal differentially modulate microtubule-associated protein 2 (MAP2) gene expression in the rat brain. Brain Res Mol Brain Res 62 : 196 205.
80. Robins L, Helzer J, Cottler L, Goldring E (1989) NIMH Diagnostic Interview Schedule: Version III Revised (DIS-III-R). Washington University Louis, St Louis, MO.
81. Rourke SB, Loberg T (1996) The neurobehavioral correlates of alcoholism, in Neuropsychological Assessment of Neuropsychiatric Disorders, 2nd ed. (Grant I, Nixon SJ eds pp 423 485. Oxford University Press, New York.
82. Salat DH, Tuch DS, Greve DN, Van der Kouwe AJ, Hevelone ND, Zaleta AK, Rosen BR, Fischl B, Corkin S, Rosas HD, Dale AM (2005a) Age-related alterations in white matter microstructure measured by diffusion tensor imaging. Neurobiol Aging 26 : 1215 1227.
83. Salat DH, Tuch DS, Hevelone ND, Fischl B, Corkin S, Rosas HD, Dale AM (2005b) Age-related changes in prefrontal white matter measured by diffusion tensor imaging. Ann NY Acad Sci 1064 : 37 49.
84. Schmahmann JD, Pandya DN (2006) Fiber Pathways of the Brain. Oxford University Press, New York.
85. Shear PK, Jernigan TL, Butters N (1994) Volumetric magnetic resonance imaging quantification of longitudinal brain changes in abstinent alcoholics. Alcohol Clin Exp Res 18 : 172 176.
86. Smith SM (2002) Fast robust automated brain extraction. Hum Brain Mapp 17 : 143 155.
87. Smith SM, De Stefano N, Jenkinson M, Matthews PM (2001) Normalized accurate measurement of longitudinal brain change. J Comput Assist Tomogr 25 : 466 475.
88. Spreen O, Strauss E (1998) A Compendium of Neuropsychological Tests. Oxford University Press, New York.
89. Sullivan EV, Deshmukh A, Desmond JE, Lim KO, Pfefferbaum A (2000) Cerebellar volume decline in normal aging, alcoholism, and Korsakoff's syndrome: relation to ataxia. Neuropsychology 14 : 341 352.
90. Sullivan EV, Marsh L, Mathalon DH, Lim KO, Pfefferbaum A (1996) Relationship between alcohol withdrawal seizures and temporal lobe white matter volume deficits. Alcohol Clin Exp Res 20 : 348 354.
91. Sullivan EV, Pfefferbaum A (2003) Diffusion tensor imaging in normal aging and neuropsychiatric disorders. Eur J Radiol 45 : 244 255.
92. Talairach J, Tournoux P (1988) Co-Planar Stereotaxic Atlas of the Human Brain. Thieme Medical Publishers Inc., New York.
93. Tang Y, Pakkenberg B, Nyengaard JR (2004) Myelinated nerve fibres in the subcortical white matter of cerebral hemispheres are preserved in alcoholic subjects. Brain Res 1029 : 162 167.
94. Tapert SF, Brown GG, Kindermann SS, Cheung EH, Frank LR, Brown SA (2001) fMRI measurement of brain dysfunction in alcohol-dependent young women. Alcohol Clin Exp Res 25 : 236 245.
95. Tapert SF, Schweinsburg AD, Barlett VC, Brown SA, Frank LR, Brown GG, Meloy MJ (2004) Blood oxygen level dependent response and spatial working memory in adolescents with alcohol use disorders. Alcohol Clin Exp Res 28 : 1577 1586.
96. Tarnowska-Dziduszko E, Bertrand E, Szpak GM (1995) Morphological changes in the corpus callosum in chronic alcoholism. Folia Neuropathol 33 : 25 29.
97. Tuch DS, Salat DH, Wisco JJ, Zaleta AK, Hevelone ND, Rosas HD (2005) Choice reaction time performance correlates with diffusion anisotropy in white matter pathways supporting visuospatial attention. Proc Natl Acad Sci USA 102 : 12212 12217.
98. Tupala E, Hall H, Halonen P, Tiihonen J (2004) Cortical dopamine D2 receptors in type 1 and 2 alcoholics measured with human whole hemisphere autoradiography. Synapse 54 : 129 137.
99. Uekermann J, Daum I, Schlebusch P, Trenckmann U (2005) Processing of affective stimuli in alcoholism. Cortex 41 : 189 194.
100. US-Army (1944) Army Individual Test Battery. Manual of Directions and Scoring. War Department, Adjutant General's Office, Washington, DC.
101. Volkow ND, Fowler JS, Wang GJ, Goldstein RZ (2002) Role of dopamine, the frontal cortex and memory circuits in drug addiction: insight from imaging studies. Neurobiol Learn Mem 78 : 610 624.
102. Volkow ND, Wang GJ, Begleiter H, Porjesz B, Fowler JS, Telang F, Wong C, Ma Y, Logan J, Goldstein R, Alexoff D, Thanos PK (2006) High levels of dopamine D2 receptors in unaffected members of alcoholic families: possible protective factors. Arch Gen Psychiatry 63 : 999 1008.
103. Volkow ND, Wang GJ, Overall JE, Hitzemann R, Fowler JS, Pappas N, Frecska E, Piscani K (1997) Regional brain metabolic response to lorazepam in alcoholics during early and late alcohol detoxification. Alcohol Clin Exp Res 21 : 1278 1284.
104. Wechsler D (1997a) Wechsler Adult Intelligence Scale-III. The Psychological Corporation, San Antonio, TX.
105. Wechsler D (1997b) Wechsler Memory Scale-III. The Psychological Corporation, San Antonio, TX.
106. Yakovlev PI, Locke S (1961) Limbic nuclei of thalamus and connections of limbic cortex. III. Corticocortical connections of the anterior cingulate gyrus, the cingulum, and the subcallosal bundle in monkey. Arch Neurol 5 : 364 400.
107. Zuckerman M, Lubin B (1965) Multiple Affect Adjective Check List. Educational and Industrial Testing Service, San Diego, CA.