Innate immune protein lactotransferrin prevents initiation and arrests progression of nasopharyngeal carcinoma

Progress in Biochemistry and Biophysics

Volumn 40, Issue 4, 2013, Pages 319-324

  Huang, Hong Bin ^a   Deng, Min ^a   Zheng, Ying ^a   Zhou, Yan Hong ^a   Zhang, Wen Ling ^a   Ma, Jian ^a   Liao, Qian Jin ^a   Xiong, Wei ^a   Li, Xiao Ling ^a   Zeng, Zhao Yang ^a   Li, Gui Yuan ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84879740162     PISSN: 10003282     EISSN: None     Source Type: Journal    
DOI: 10.3724/SP.J.1206.2012.00540     Document Type: Review

References (72)

1. Zeng Z, Huang H, Zhang W, et al. Nasopharyngeal carcinoma: advances in genomics and molecular genetics. Sci China Life Sci, 2011, 54(10):966-975
2. Deng M, Tang H, Zhou Y, et al. miR-216b suppresses tumor growth and invasion by targeting KRAS in nasopharyngeal carcinoma. J Cell Sci, 2011, 124(Pt 17):2997-3005
3. Li W, Li X, Wang W, et al. NOR1 is an HSF1-and NRF1-regulated putative tumor suppressor inactivated by promoter hypermethylation in nasopharyngeal carcinoma. Carcinogenesis, 2011, 32(9):1305-1314
4. Liao Q, Guo X, Li X, et al. Prohibitin is an important biomarker for nasopharyngeal carcinoma progression and prognosis. Eur J Cancer Prev, 2013, 22(1):68-76
5. Yu Z, Lu J, Yu H, et al. A precise excision of the complete Epstein-Barr virus genome in a plasmid based on a bacterial artificial chromosome. J Virol Methods, 2011, 176 (1-4):103-107
6. Lu J H, Tang Y L, Yu H B, et al. Epstein-Barr virus facilitates the malignant potential of immortalized epithelial cells: from latent genome to viral production and maintenance. Lab Invest, 2010, 90(2):196-209
7. Li S, Du H, Wang Z, et al. Meta-analysis of the relationship between Epstein-Barr virus infection and clinicopathological features of patients with gastric carcinoma. Sci China Life Sci, 2010, 53(4):524-530
8. Zhang Y, Zhao H, He X, et al. Effects of Epstein-Barr virus infection on the development of multiple myeloma after liver transplantation. Sci China Life Sci, 2012, 55(8):735-743
9. Li Z, Wang L, Zhang X, et al. Chin J Med Genet, 2001, 18(5):338-342
10. Deng L, Jing N, Tan G, et al. A common region of allelic loss on chromosome region 3p25.3-26.3 in nasopharyngeal carcinoma. Genes Chromosomes Cancer, 1998, 23(1):21-25
11. Yang S, Hu H, Deng M, et al. Prog Biochem Biophys, 2010, 37(2):167-174
12. Li L, He X S, Luo Q, et al. Prog Biochem Biophys, 2011, 38(3):248-253
13. Hou D F, Guan Y J, Guan R, et al. Prog Biochem Biophys, 2011, 38(8):713-723
14. Zhang Z W, Zhang Q, Yu Y H, et al. Prog Biochem Biophys, 2009, 36(5):580-586
15. Xiong W, Zeng Z Y, Xia J H, et al. A susceptibility locus at chromosome 3p21 linked to familial nasopharyngeal carcinoma. Cancer Res, 2004, 64(6):1972-1974
16. Zeng Z, Zhou Y, Zhang W, et al. Family-based association analysis validates chromosome 3p21 as a putative nasopharyngeal carcinoma susceptibility locus. Genet Med, 2006, 8(3):156-160
17. Ng C C, Yew P Y, Puah S M, et al. A genome-wide association study identifies ITGA9 conferring risk of nasopharyngeal carcinoma. J Hum Genet, 2009, 54(7):392-397
18. Salipante S J, Mealiffe M E, Wechsler J, et al. Mutations in a gene encoding a midbody kelch protein in familial and sporadic classical Hodgkin lymphoma lead to binucleated cells. Proc Natl Acad Sci USA, 2009, 106(35):14920-14925
19. Zeng Z, Zhou Y, Xiong W, et al. Analysis of gene expression identifies candidate molecular markers in nasopharyngeal carcinoma using microdissection and cDNA microarray. J Cancer Res Clin Oncol, 2007, 133(2):71-81
20. Zeng Z Y, Zhou Y H, Zhang W L, et al. Gene expression profiling of nasopharyngeal carcinoma reveals the abnormally regulated Wnt signaling pathway. Hum Pathol, 2007, 38(1):120-133
21. Zhou Y, Zeng Z, Zhang W, et al. Identification of candidate molecular markers of nasopharyngeal carcinoma by microarray analysis of subtracted cDNA libraries constructed by suppression subtractive hybridization. Eur J Cancer Prev, 2008, 17(6):561-571
22. Zhang W, Zeng Z, Fan S, et al. Evaluation of the prognostic value of TGF-beta superfamily type I receptor and TGF-bcta type II receptor expression in nasopharyngeal carcinoma using high-throughput tissue microarrays. J Mol Histol, 2012, 43(3):297-306
23. Zhou Y H, Zeng Z Y, Xiong W, et al. Prog Biochem Biophys, 2005, 32(5):463-467
24. Zhou Y H, Zhang B C, Zeng Z Y, et al. Prog Biochem Biophys, 2005, 32(12):1121-1129
25. Zhou Y, Zeng Z, Zhang W, et al. Lactotransferrin: a candidate tumor suppressor-Deficient expression in human nasopharyngeal carcinoma and inhibition of NPC cell proliferation by modulating the mitogen-activated protein kinase pathway. Int J Cancer, 2008, 123(9):2065-2072
26. Fan S Q, Zhang W L, Xiong W, et al. Prog Biochem Biophys, 2005, 32(5):474-479
27. Fan S Q, Zhang W L, Zhou M, et al. Prog Biochem Biophys, 2008, 35(9):1014-1020
28. Fan S Q, Zhang W L, Xu L N, et al. Prog Biochem Biophys, 2009, 36(5):616-623
29. Zhou Y, Wang W, Zheng D, et al. Risk of nasopharyngeal carcinoma associated with polymorphic lactotransferrin haplotypes. Med Oncol, 2012, 29(3):1456-1462
30. Xiong W, Zeng Z Y, Li X L, et al. Acta Biochim Biophys Sin, 2002, 34(4):512-515
31. Xiong W, Zeng Z Y, Shen S R, et al. Prog Biochem Biophys, 2002, 29(5):766-770
32. Xiong W, Zeng Z Y, Xiao B Y, et al. Prog Biochem Biophys, 2003, 30(3):401-405
33. Huang J, Zhao Y P, Li Q, et al. Prog Biochem Biophys, 2012, 39(7):678-686
34. Watanabe T, Nagura H, Watanabe K, et al. The binding of human milk lactofemn to immunoglobulin A. FEBS Lett, 1984, 168(2):203-207
35. Leng F. Recent progress of immunology research in China. Sci China Life Sci, 2011, 54(11):1068-1070
36. Qi Y, Li D K.. Prog Biochem Biophys, 2011, 38(10):900-907
37. Xing Y L, Zheng Y, Wang K, et al. Prog Biochem Biophys, 2011, 38(12):1099-1105
38. Zhang J J, Zhou K Y, Cai C. Prog Biochem Biophys, 2011, 38(1):20-27
39. An H, Qian C, Cao X. Regulation of Toll-like receptor signaling in the innate immunity. Sci China Life Sci, 2010, 53(1):34-43
40. Dai X, Zhang L, Hong T. Host cellular signaling induced by influenza virus. Sci China Life Sci, 2011, 54(1):68-74
41. Zheng D. A highlight of recent advances in immunology. Sci China Life Sci, 2012, 54(12):1151-1152
42. Zhang W, Zeng Z, Zhou Y, et al. Identification of aberrant cell cycle regulation in Epstein-Barr virus-associated nasopharyngeal carcinoma by cDNA microarray and gene set enrichment analysis. Acta Biochim Biophys Sin, 2009, 41(5):414-428
43. Fan S Q, Ma J, Zhou J, et al. Differential expression of Epstein-Barr virus-encoded RNA and several tumor-related genes in various types of nasopharyngeal epithelial lesions and nasopharyngeal carcinoma using tissue microarray analysis. Hum Pathol, 2006, 37(5):593-605
44. Yang W. Some research advances of immune mechanism during infection in China. Sci China Life Sci, 2012, 54(12):1153-1155
45. Yu H, Lu J, Zuo L, et al. Epstein-Barr virus downregulates microRNA 203 through the oncoprotein latent membrane protein 1: a contribution to increased tumor incidence in epithelial cells. J Virol, 2012, 86(6):3088-3099
46. Zuo L L, Lu J H, Yu H B, et al. Prog Biochem Biophys, 2011, 38(6):563-567
47. Zheng Y, Zhang W, Ye Q, et al. Inhibition of Epstein-Barr virus infection by lactoferrin. J Innate Immun, 2012, 4(4):387-398
48. Wang Z, Yang S, Zhou L, et al. Specific cellular immune responses in mice immunized with DNA, adeno-associated virus and adenoviral vaccines of Epstein-Barr virus-LMP2 alone or in combination. Sci China Life Sci, 2011, 54(3):263-266
49. Wang G, Lu J. Retrovirus-mediated delivery of an IL-4 receptor antagonist inhibits allergic responses in a murine model of asthma. Sci China Life Sci, 2010, 53(10):1215-1220
50. Wang Z, Su W, Zhou X F, et al. Prog Biochem Biophys, 2012, 39(2):168-174
51. Xue Y, Liu L L, He F, et al. Prog Biochem Biophys, 2011, 38(4):311-319
52. Zhao Y, Xue Y, Jiang X, et al. Prog Biochem Biophys, 2012, 39(5):483-490
53. Liu Z L, Sun W, He F C, et al. Prog Biochem Biophys, 2012, 39(5):416-422
54. Wang Y, Zhang P, Liu Y, et al. TRAF-mediated regulation of immune and inflammatory responses. Sci China Life Sci, 2010, 53(2):159-168
55. Liao Q, Guo X, Li X, et al. Analysis of the contribution of nasopharyngeal epithelial cancer cells to the induction of a local inflammatory response. J Cancer Res Clin Oncol, 2012, 138(1):57-64
56. Liu S, Wang S, Wu Y, et al. Production of proinflammatory cytokines in the human THP-1 monocyte cell line following induction by Tp0751, a recombinant protein of Treponema pallidum. Sci China Life Sci, 2010, 53(2):229-233
57. Fan P J, Yang X H, Xiao M Z, et al. Prog Biochem Biophys, 2011, 38(9):842-849
58. Sun P, Zhang Q, Han J, et al. TLR4 signaling induced TLR2 expression in the process of mimic cerebral ischemia/reperfusion in vitro. Sci China Life Sci, 2010, 53(2):223-228
59. Wei Y. NF-kappaB, a hot topic in biochemical and medical studies in China. Sci China Life Sci, 2010, 53(12):1485-1487
60. Wang S B, Lei W, Xu Y H, et al. Prog Biochem Biophys, 2012, 39(2):161-167
61. Yang L P, Yao Y M, Ye Q N, et al. Prog Biochem Biophys, 2011, 38(12):1145-1152
62. Matloob A, Pan L N, Pan H, et al. Prog Biochem Biophys, 2011, 38(6):543-550
63. Ma L, Tang H, Ren Y, et al. p38alpha MAP kinase phosphorylates RCAN1 and regulates its interaction with calcineurin. Sci China Life Sci, 2012, 55(7):559-566
64. Liang H, Liu T, Chen F, et al. A full-length 3D structure for MAPK/ERK kinase 2 (MEK2). Sci China Life Sci, 2011, 54(4):336-341
65. Rajasekaran R, Sethumadhavan R. Exploring the structural and functional effect of pRB by significant nsSNP in the coding region of RBI gene causing retinoblastoma. Sci China Life Sci, 2010, 53(2):234-240
66. Deng M, Zhang W, Tang H, et al. Lactotransferrin acts as a tumor suppressor in nasopharyngeal carcinoma by repressing AK. T through multiple mechanisms. Oncogene, 2012, doi: 10.1038/one. 2012.434
67. Pan W N, Li F, Mao X H, et al. Prog Biochem Biophys, 2011, 38(12):1153-1161
68. Feng S, Wang Y, Wang X, et al. Caveolin-1 gene silencing promotes the activation of PI3K/AK. T dependent on Eralpha36 and the transformation of MCF10ACE. Sci China Life Sci, 2011, 53(5):598-605
69. Tang H, Fu Y. A new role for T cells in dampening innate inflammatory responses. Sci China Life Sci, 2010, 53(2):190-194
70. Huang H B, Liang F, Xiong W, et al. Prog Biochem Biophys, 2012, 39(1):35-44
71. Cao C S, Shen W Z, Li Y L, et al. Prog Biochem Biophys, 2011, 38(3):254-261
72. Liu Q, Zhang X, Zeng Y. Targeted and personalized therapy for cancer: theory and practice in China. Sci China Life Sci, 2011, 54(12):1081-1084