AMD3100 aggravates atherogenesis by up-regulating inflammatory factor expression and down-regulating SDF-1/CXCR4 axis

Progress in Biochemistry and Biophysics

Volumn 39, Issue 2, 2012, Pages 168-174

  Wang, Zuo ^a   Su, Wei ^a   Zhou, Xiao Feng ^b   Zhang, Kai ^a   Li, Shuang ^a   Ma, Xiao Feng ^a   Jiang, Zhi Sheng ^a  

^a UNIVERSITY OF SOUTH CHINA   (China)

^b QINGHAI UNIVERSITY   (China)

Author keywords

AMD3100; Atherosclerosis; CXCR4; NF B; SDF 1 ; TNF

Indexed keywords

ANIMALIA; MUS;

EID: 84860861984     PISSN: 10003282     EISSN: None     Source Type: Journal    
DOI: 10.3724/SP.J.1206.2011.00187     Document Type: Article

References (20)

1. Steinberg D. Atherogenesis in perspective: Hypercholesterolemia and inflammation as partners in crime. Nat Med, 2002, 8 (11): 1211-1217 (Pubitemid 35373551)
2. Libby P. Inflammation in atherosclerosis. Nature, 2002, 420 (6): 868-874 (Pubitemid 36019640)
3. Abi-Younes S, Sauty A, Mach F, et al. The stromal cell-derived factor-1 chemokine is a potent platelet agonist highly expressed in atherosclerotic plaques. Circ Res, 1999, 86(2): 131-138 (Pubitemid 30086172)
4. Schober A, Knarren S, Lietz M, et al. Crucial role of stromal cell-derived factor-1α in neointima formation after vascular injury in apolipoprotein E-deficient mice. Circulation, 2003, 108 (2): 491-497
5. Sakihama H, Masunaga T, Yamashita K, et al. Stromal cell-derived factor-1 and CXCR4 interaction is critical for development of transplant arteriosclerosis. Circulation, 2004, 110(18): 2924-2930 (Pubitemid 39473619)
6. Damås J K, Waehre T, Yndestad A, et al. Stromal cell derived factor-1 in unstable angina potential antiinflammatory and matrix stabilizing effects. Circulation, 2002, 106(1): 36-42 (Pubitemid 34747439)
7. Zhou X F, Wang Z. Chin J Arteriosclerosis, 2008, 16(6): 445-448
8. Wang Z, Zhou X F, Wang R, et al. Prog Biochem Biophys, 2008, 35(7): 807-813
9. WeintraubWS, HarrisonD G. Creactive protein, inflammation and atherosclerosis: Do we really understand it yet?. Eur Heart J, 2000, 21(12): 958-960 (Pubitemid 30312081)
10. Belton O, Byrne D, Kearney D, et al. Cyclooxygenase-1 and -2-dependent prostacyclin formation in patients with atherosclerosis. Circulation, 2000, 102(8) : 840-845
11. κB structure function relationship of its protein subunits. Biochem J, 1993, 290(2): 297-308
12. Massberg S, Konrad I, Schürzinger K, et al. Platelets secrete stromal cell-derived factor 1α and recruit bone marrow-derived progenitor cells to arterial thrombi in vivo. J Exper Med, 2006, 203(5): 1221-1233 (Pubitemid 43736592)
13. Gear A R, Camerini D. Platelet chemokines and chemokines receptors: Linking hemostasis, inflammation and host defence. Microcirculation, 2003, 10(3-4): 335-350 (Pubitemid 39004260)
14. Zeiffer U, Schober A, Lietz M, et al. Neointimal Smooth muscle cells display a proinflammatory phenotype resulting in increased leukocyte recruitment mediated by p-selectin and chemokines. Cir Res, 2004, 94(6): 776-784 (Pubitemid 38451739)
15. Gupta S K, Pillarisetti K, Lysko P G. Modulation of CXCR4 expression and SDF-1alpha functional activity during differentiation of human monocytes and macrophages. J Leukoc Biol, 1999, 66(1): 135-143 (Pubitemid 29321381)
16. Han K H, Hong K H, Ko J, et al. Lysophosphatidylcholine up-regulates CXCR4 chemokine receptor experession in human CD4 T cells. J Leukoc Biol, 2004, 76(1): 195-202 (Pubitemid 38857187)
17. PoznanskyMC, Olszak I T, Foxall R, et al. Active movement of T cells away froma chemokine. Nat Med, 2000, 6(5): 543-548 (Pubitemid 30305904)
18. Salvucci O, Basik M, Yao L, et al. Evidence for the involvement of SDF-1 and CXCR4 in the disruption of endothelial cell-branching morphogenesis and angiogenesis by TNF-alpha and IFN-gamma. J Leukoc Biol. 2004, 76(1): 217-226 (Pubitemid 38857190)
19. Han Y, Wang J, He T, et al. TNF-α down-regulates CXCR4 expression in primary astrocytes. Brain Res, 2001, 888(1): 1-10 (Pubitemid 32056257)
20. Ueda Y, Yang K, Foster S J, et al. Inflammation controls B lymphopoiesis by regulating chemokine CXCL12 expression. J Exp Med, 2004, 199(1): 47-58