Prohibitin is an important biomarker for nasopharyngeal carcinoma progression and prognosis

European Journal of Cancer Prevention

Volumn 22, Issue 1, 2013, Pages 68-76

  Liao, Qianjin ^a,b   Guo, Xiaofang ^a   Li, Xiaoling ^a   Xiong, Wei ^a   Li, Xiayu ^c   Yang, Jing ^a   Chen, Pan ^a   Zhang, Wenling ^a   Yu, Haibo ^a   Tang, Hailin ^a,b   Deng, Min ^a,b   Liang, Fang ^a   Wu, Minghua ^a   Luo, Zhaohui ^a   Wang, Rong ^a   Zeng, Xi ^a,b   Zeng, Zhaoyang ^a   Li, Guiyuan ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b UNIVERSITY OF SOUTH CHINA   (China)

^c THE THIRD XIANGYA HOSPITAL OF CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

2 D DIGE; immunohistochemistry; LPLUNC1; MALDI TOF TOF; nasopharyngeal carcinoma; Prohibitin; tissue microarray

Indexed keywords

BIOLOGICAL MARKER; MESSENGER RNA; PROHIBITIN;

ADULT; APOPTOSIS; ARTICLE; CANCER GROWTH; CANCER STAGING; CELL PROLIFERATION; CONTROLLED STUDY; CORRELATION ANALYSIS; DOWN REGULATION; EPITHELIUM; FEMALE; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KAPLAN MEIER METHOD; LOG RANK TEST; MAJOR CLINICAL STUDY; MALE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; METASTASIS; NASOPHARYNX CARCINOMA; NASOPHARYNX EPITHELIUM; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN FUNCTION; SURVIVAL TIME; TISSUE LEVEL; TISSUE MICROARRAY; TRANSCRIPTION REGULATION; TWO DIMENSIONAL DIFFERENCE GEL ELECTROPHORESIS;

ADULT; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DISEASE PROGRESSION; DOWN-REGULATION; FEMALE; HUMANS; MALE; MIDDLE AGED; NASOPHARYNGEAL NEOPLASMS; OLFACTORY MUCOSA; PROGNOSIS; REPRESSOR PROTEINS; TUMOR MARKERS, BIOLOGICAL;

EID: 84870991918     PISSN: 09598278     EISSN: 14735709     Source Type: Journal    
DOI: 10.1097/CEJ.0b013e328354d351     Document Type: Article

References (26)

1. Bingle CD, Wilson K, Lunn H, Barnes FA, High AS, Wallace WA, et al. (2010). Human LPLUNC1 is a secreted product of goblet cells and minor glands of the respiratory and upper aerodigestive tracts. Histochem Cell Biol 133:505-515
2. Chander H, Halpern M, Resnick-Silverman L, Manfredi JJ, Germain D (2010). Skp2B attenuates p53 function by inhibiting prohibitin. EMBO Rep 11: 220-225
3. Chumbalkar VC, Subhashini C, Dhople VM, Sundaram CS, Jagannadham MV, Kumar KN, et al. (2005). Differential protein expression in human gliomas and molecular insights. Proteomics 5:1167-1177
4. Cilia M, Fish T, Yang X, McLaughlin M, Thannhauser TW, Gray S (2009). A comparison of protein extraction methods suitable for gel-based proteomic studies of aphid proteins. J Biomol Tech 20:201-215
5. Dai Z, Yin J, He H, Li W, Hou C, Qian X, et al. (2010). Mitochondrial comparative proteomics of human ovarian cancer cells and their platinum-resistant sublines. Proteomics 10:3789-3799
6. Dart DA, Spencer-Dene B, Gamble SC, Waxman J, Bevan CL (2009). Manipulating prohibitin levels provides evidence for an in vivo role in androgen regulation of prostate tumours. Endocr Relat Cancer 16:1157-1169
7. Fan SQ, Ma J, Zhou J, Xiong W, Xiao BY, Zhang WL, et al. (2006). Differential expression of Epstein-Barr virus-encoded RNA and several tumorrelated genes in various types of nasopharyngeal epithelial lesions and nasopharyngeal carcinoma using tissue microarray analysis. Hum Pathol 37:593-605
8. Fusaro G, Dasgupta P, Rastogi S, Joshi B, Chellappan S (2003). Prohibitin induces the transcriptional activity of p53 and is exported from the nucleus upon apoptotic signaling. J Biol Chem 278:47853-47861
9. Gregory-Bass RC, Olatinwo M, Xu W, Matthews R, Stiles JK, Thomas K, et al. (2008). Prohibitin silencing reverses stabilization of mitochondrial integrity and chemoresistance in ovarian cancer cells by increasing their sensitivity to apoptosis. Int J Cancer 122:1923-1930
10. Gu Y, Ande SR, Mishra S (2010). Altered O-GlcNAc modification and phosphorylation of mitochondrial proteins in myoblast cells exposed to high glucose. Arch Biochem Biophys 505:98-104
11. He B, Feng Q, Mukherjee A, Lonard DM, DeMayo FJ, Katzenellenbogen BS, et al. (2008). A repressive role for prohibitin in estrogen signaling. Mol Endocrinol 22:344-360
12. He Q, Zhang SQ, Chu YL, Jia XL, Zhao LH, Wang XL (2010). Separation and identification of differentially expressed nuclear matrix proteins in breast carcinoma forming. Acta Oncol 49:76-84
13. Kang X, Zhang L, Sun J, Ni Z, Ma Y, Chen X, et al. (2008). Prohibitin: A potential biomarker for tissue-based detection of gastric cancer. J Gastroenterol 43:618-625
14. Ko KS, Tomasi ML, Iglesias-Ara A, French BA, French SW, Ramani K, et al. (2010). Liver-specific deletion of prohibitin 1 results in spontaneous liver injury, fibrosis, and hepatocellular carcinoma in mice. Hepatology 52: 2096-2108
15. Liu T, Tang H, Lang Y, Liu M, Li X (2009). MicroRNA-27a functions as an oncogene in gastric adenocarcinoma by targeting prohibitin. Cancer Lett 273:233-242
16. Merkwirth C, Langer T (2009). Prohibitin function within mitochondria: Essential roles for cell proliferation and cristae morphogenesis. Biochim Biophys Acta 1793:27-32
17. Mishra S, Murphy LC, Murphy LJ (2006). The prohibitins: Emerging roles in diverse functions. J Cell Mol Med 10:353-363
18. Rajalingam K, Wunder C, Brinkmann V, Churin Y, Hekman M, Sievers C, et al. (2005). Prohibitin is required for Ras-induced Raf-MEK-ERK activation and epithelial cell migration. Nat Cell Biol 7:837-843
19. Ren HZ, Wang JS, Wang P, Pan GQ, Wen JF, Fu H, et al. (2010). Increased expression of prohibitin and its relationship with poor prognosis in esophageal squamous cell carcinoma. Pathol Oncol Res 16:515-522
20. Rizwani W, Alexandrow M, Chellappan S (2009). Prohibitin physically interacts with MCM proteins and inhibits mammalian DNA replication. Cell Cycle 8:1621-1629
21. Wang R,Wang Z, Yang J, Liu X,Wang L, Guo X, et al. (2011). LRRC4 inhibits the proliferation of human glioma cells by modulating the expression of STMN1 and microtubule polymerization. J Cell Biochem 112:3621-3629
22. Yang Y, Yang Y, Li X, Peng C, Guo Q, Shen S, et al. (2007). The study of LPLUNC1 gene inhibit human nasopharyngeal carcinoma cell line HNE1 growth and proliferation. Prog Biochem Biophys 34:9
23. Zhou Y, Zeng Z, Zhang W, Xiong W, Li X, Zhang B, et al. (2008). Identification of candidate molecular markers of nasopharyngeal carcinoma by microarray analysis of subtracted cDNA libraries constructed by suppression subtractive hybridization. Eu J Cancer Prev 17:561-571
24. Zhang B, Nie X, Xiao B, Xiang J, Shen S, Gong J, et al. (2003). Identification of tissue-specific genes in nasopharyngeal epithelial tissue and differentially expressed genes in nasopharyngeal carcinoma by suppression subtractive hybridization and cDNA microarray. Genes Chromosomes Cancer 38:80-90
25. Zhang W, Zeng Z, Zhou Y, Xiong W, Fan S, Xiao L, et al. (2009). Identification of aberrant cell cycle regulation in Epstein-Barr virus-associated nasopharyngeal carcinoma by cDNA microarray and gene set enrichment analysis. Acta Biochim Biophys Sin (Shanghai) 41:414-428
26. Zhu B, Zhai J, Zhu H, Kyprianou N (2010). Prohibitin regulates TGF-beta induced apoptosis as a downstream effector of Smad-dependent and -independent signaling. Prostate 70:17-26