Mutations in a gene encoding a midbody kelch protein in familial and sporadic classical Hodgkin lymphoma lead to binucleated cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 35, 2009, Pages 14920-14925

  Salipante, Stephen J ^a   Mealiffe, Matthew E ^a,g   Wechsler, Jeremy ^a   Krem, Maxwell M ^a   Liu, Yajuan ^a   Namkoong, Shinae ^a   Bhagat, Govind ^b   Kirchhoff, Tomas ^c   Offit, Kenneth ^c   Lynch, Henry ^d   Wiernik, Peter H ^e   Roshal, Mikhail ^a   McMaster, Mary Lou ^f   Tucker, Margaret ^f   Fromm, Jonathan R ^a   Goldin, Lynn R ^f   Horwitz, Marshall S ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b College of Physicians and Surgeons of Columbia University ^*  (United States)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^d CREIGHTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e NEW YORK MEDICAL COLLEGE   (United States)

^f NATIONAL CANCER INSTITUTE   (United States)

^g Perlegen Sciences Inc   (United States)

Author keywords

Cancer; Cytokinesis

Indexed keywords

CARRIER PROTEIN; PROTEIN KLHDC8B; UNCLASSIFIED DRUG;

5' UNTRANSLATED REGION; ARTICLE; B LYMPHOCYTE; CELL DIVISION; CELL NUCLEUS; CHROMOSOME 2; CHROMOSOME 3; CLASSICAL HODGKIN LYMPHOMA; CONTROLLED STUDY; CYTOKINESIS; DNA POLYMORPHISM; GENE EXPRESSION; GENE MAPPING; GENE MUTATION; GENE TRANSLOCATION; HETEROZYGOSITY LOSS; HUMAN; HUMAN CELL; NUCLEAR DIVISION; PRIORITY JOURNAL; PROTEIN DEGRADATION; RECIPROCAL CHROMOSOME TRANSLOCATION; REED STERNBERG CELL; RNA INTERFERENCE; T LYMPHOCYTE;

5' UNTRANSLATED REGIONS; ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANIMALS; ANTIGENS, NEOPLASM; BASE SEQUENCE; CELL NUCLEUS; CHROMOSOMES, HUMAN, PAIR 2; CHROMOSOMES, HUMAN, PAIR 3; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HODGKIN DISEASE; HUMANS; MALE; MIDDLE AGED; MUTATION; PEDIGREE; REED-STERNBERG CELLS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, NUCLEIC ACID; YOUNG ADULT;

EID: 70349279998     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0904231106     Document Type: Article

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