-
1
-
-
0029007407
-
PKR: A new name and new roles
-
Proud C G. PKR: A new name and new roles. Trends Biochem Sci, 1995, 20: 241-246.
-
(1995)
Trends Biochem Sci
, vol.20
, pp. 241-246
-
-
Proud, C.G.1
-
2
-
-
0033230617
-
PKR; a sentinel kinase for cellular stress
-
Williams B R. PKR; a sentinel kinase for cellular stress. Oncogene, 1999, 18: 6112-6120.
-
(1999)
Oncogene
, vol.18
, pp. 6112-6120
-
-
Williams, B.R.1
-
3
-
-
67650917895
-
Influenza B virus ribonucleoprotein is a potent activator of the antiviral kinase PKR
-
Dauber B, Martinez-Sobrido L, Schneider J, et al. Influenza B virus ribonucleoprotein is a potent activator of the antiviral kinase PKR. PLoS Pathog, 2009, 5: e1000473.
-
(2009)
PLoS Pathog
, vol.5
-
-
Dauber, B.1
Martinez-Sobrido, L.2
Schneider, J.3
-
4
-
-
42449121506
-
PKR in innate immunity, cancer, and viral oncolysis
-
Balachandran S, Barber G N. PKR in innate immunity, cancer, and viral oncolysis. Methods Mol Biol, 2007, 383: 277-301.
-
(2007)
Methods Mol Biol
, vol.383
, pp. 277-301
-
-
Balachandran, S.1
Barber, G.N.2
-
5
-
-
34347225099
-
The dsRNA protein kinase PKR: virus and cell control
-
Garcia M A, Meurs E F, Esteban M. The dsRNA protein kinase PKR: virus and cell control. Biochimie, 2007, 89: 799-811.
-
(2007)
Biochimie
, vol.89
, pp. 799-811
-
-
Garcia, M.A.1
Meurs, E.F.2
Esteban, M.3
-
6
-
-
0033679958
-
Essential role for the dsRNA-dependent protein kinase PKR in innate immunity to viral infection
-
Balachandran S, Roberts P C, Brown L E, et al. Essential role for the dsRNA-dependent protein kinase PKR in innate immunity to viral infection. Immunity, 2000, 13: 129-141.
-
(2000)
Immunity
, vol.13
, pp. 129-141
-
-
Balachandran, S.1
Roberts, P.C.2
Brown, L.E.3
-
7
-
-
0029842883
-
Possible involvement of double-stranded RNA-activated protein kinase in cell death by influenza virus infection
-
Takizawa T, Ohashi K, Nakanishi Y. Possible involvement of double-stranded RNA-activated protein kinase in cell death by influenza virus infection. J Virol, 1996, 70: 8128-8132.
-
(1996)
J Virol
, vol.70
, pp. 8128-8132
-
-
Takizawa, T.1
Ohashi, K.2
Nakanishi, Y.3
-
8
-
-
0033970831
-
Alpha/beta interferons potentiate virus-induced apoptosis through activation of the FADD/Caspase-8 death signaling pathway
-
Balachandran S, Roberts P C, Kipperman T, et al. Alpha/beta interferons potentiate virus-induced apoptosis through activation of the FADD/Caspase-8 death signaling pathway. J Virol, 2000, 74: 1513-1523.
-
(2000)
J Virol
, vol.74
, pp. 1513-1523
-
-
Balachandran, S.1
Roberts, P.C.2
Kipperman, T.3
-
9
-
-
33646517711
-
Binding of the influenza A virus NS1 protein to PKR mediates the inhibition of its activation by either PACT or double-stranded RNA
-
Li S, Min J Y, Krug R M, et al. Binding of the influenza A virus NS1 protein to PKR mediates the inhibition of its activation by either PACT or double-stranded RNA. Virology, 2006, 349: 13-21.
-
(2006)
Virology
, vol.349
, pp. 13-21
-
-
Li, S.1
Min, J.Y.2
Krug, R.M.3
-
10
-
-
0028847292
-
Binding of the influenza virus NS1 protein to double-stranded RNA inhibits the activation of the protein kinase that phosphorylates the elF-2 translation initiation factor
-
Lu Y, Wambach M, Katze M G, et al. Binding of the influenza virus NS1 protein to double-stranded RNA inhibits the activation of the protein kinase that phosphorylates the elF-2 translation initiation factor. Virology, 1995, 214: 222-228.
-
(1995)
Virology
, vol.214
, pp. 222-228
-
-
Lu, Y.1
Wambach, M.2
Katze, M.G.3
-
12
-
-
3142724031
-
Toll-like receptor signalling
-
Akira S, Takeda K. Toll-like receptor signalling. Nat Rev Immunol, 2004, 4: 499-511.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 499-511
-
-
Akira, S.1
Takeda, K.2
-
13
-
-
1542317550
-
Innate Antiviral responses by means of TLR7-Mediated recognition of single-stranded RNA
-
Diebold S S, Kaisho T, Hemmi H, et al. Innate Antiviral responses by means of TLR7-Mediated recognition of single-stranded RNA. Science, 2004, 303: 1529-1531.
-
(2004)
Science
, vol.303
, pp. 1529-1531
-
-
Diebold, S.S.1
Kaisho, T.2
Hemmi, H.3
-
14
-
-
1842631428
-
Recognition of sin gle-stranded RNA viruses by Toll-like receptor 7
-
Lund J M, Alexopoulou L, Sato A, et al. Recognition of sin gle-stranded RNA viruses by Toll-like receptor 7. Proc Natl Acad Sci USA, 2004, 101: 5598-5603.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 5598-5603
-
-
Lund, J.M.1
Alexopoulou, L.2
Sato, A.3
-
15
-
-
14044267522
-
Involvement of toll-like receptor 3 in the immune response of lung epithelial cells to double-stranded RNA and influenza A virus
-
Guillot L, Le Goffic R, Bloch S, et al. Involvement of toll-like receptor 3 in the immune response of lung epithelial cells to double-stranded RNA and influenza A virus. J Biol Chem, 2005, 280: 5571-5580.
-
(2005)
J Biol Chem
, vol.280
, pp. 5571-5580
-
-
Guillot, L.1
Le Goffic, R.2
Bloch, S.3
-
16
-
-
23244461479
-
p38 mitogen-activated protein kinase-dependent hyperinduction of tumor necrosis factor alpha expression in response to avian influenza virus H5N1
-
Lee D C, Cheung C Y, Law A H, et al. p38 mitogen-activated protein kinase-dependent hyperinduction of tumor necrosis factor alpha expression in response to avian influenza virus H5N1. J Virol, 2005, 79: 10147-10154.
-
(2005)
J Virol
, vol.79
, pp. 10147-10154
-
-
Lee, D.C.1
Cheung, C.Y.2
Law, A.H.3
-
17
-
-
0038105474
-
ASK1 regulates influenza virus infection-induced apoptotic cell death
-
Maruoka S, Hashimoto S, Gon Y, et al. ASK1 regulates influenza virus infection-induced apoptotic cell death. Biochem Biophys Res Commun, 2003, 307: 870-876.
-
(2003)
Biochem Biophys Res Commun
, vol.307
, pp. 870-876
-
-
Maruoka, S.1
Hashimoto, S.2
Gon, Y.3
-
18
-
-
0034653508
-
p38 mitogen-activated protein kinase and c-jun-NH2-terminal kinase regulate RANTES production by influenza virus-infected human bronchial epithelial cells
-
Kujime K, Hashimoto S, Gon Y, et al. p38 mitogen-activated protein kinase and c-jun-NH2-terminal kinase regulate RANTES production by influenza virus-infected human bronchial epithelial cells. J Immunol, 2000, 164: 3222-3228.
-
(2000)
J Immunol
, vol.164
, pp. 3222-3228
-
-
Kujime, K.1
Hashimoto, S.2
Gon, Y.3
-
19
-
-
0035815684
-
Influenza virus-induced AP-1-dependent gene expression requires activation of the JNK signaling pathway
-
Ludwig S, Ehrhardt C, Neumeier E R, et al. Influenza virus-induced AP-1-dependent gene expression requires activation of the JNK signaling pathway. J Biol Chem, 2001, 276: 10990-10998.
-
(2001)
J Biol Chem
, vol.276
, pp. 10990-10998
-
-
Ludwig, S.1
Ehrhardt, C.2
Neumeier, E.R.3
-
20
-
-
78751674806
-
The MAPK-activated kinase RSK2 plays a role in innate immune responses to influenza virus infection
-
Kakugawa S, Shimojima M, Goto H, et al. The MAPK-activated kinase RSK2 plays a role in innate immune responses to influenza virus infection. J Virol, 2009.
-
(2009)
J Virol
-
-
Kakugawa, S.1
Shimojima, M.2
Goto, H.3
-
21
-
-
50449106423
-
Toll-like receptor 2 expression level on monocytes in patients with viral infections: Monitoring infection severity
-
Kajiya T, Orihara K, Hamasaki S, et al. Toll-like receptor 2 expression level on monocytes in patients with viral infections: Monitoring infection severity. J Infect, 2008, 57: 249-259.
-
(2008)
J Infect
, vol.57
, pp. 249-259
-
-
Kajiya, T.1
Orihara, K.2
Hamasaki, S.3
-
22
-
-
33645091208
-
Influenza a viruses upregulate neutrophil toll-like receptor 2 expression and function
-
Lee R M, White M R, Hartshorn K L. Influenza a viruses upregulate neutrophil toll-like receptor 2 expression and function. Scand J Immunol, 2006, 63: 81-89.
-
(2006)
Scand J Immunol
, vol.63
, pp. 81-89
-
-
Lee, R.M.1
White, M.R.2
Hartshorn, K.L.3
-
23
-
-
35748973890
-
Negative regulation of TLR-signaling pathways by activating transcription factor-3
-
Whitmore M M, Iparraguirre A, Kubelka L, et al. Negative regulation of TLR-signaling pathways by activating transcription factor-3. J Immunol, 2007, 179: 3622-3630.
-
(2007)
J Immunol
, vol.179
, pp. 3622-3630
-
-
Whitmore, M.M.1
Iparraguirre, A.2
Kubelka, L.3
-
24
-
-
70349139611
-
Functions of the cytoplasmic RNA sensors RIG-I and MDA-5: Key regulators of innate immunity
-
Barral P M, Sarkar D, Su Z-z, et al. Functions of the cytoplasmic RNA sensors RIG-I and MDA-5: Key regulators of innate immunity. Pharmacol Ther, 2009, 124: 219-234.
-
(2009)
Pharmacol Ther
, vol.124
, pp. 219-234
-
-
Barral, P.M.1
Sarkar, D.2
Su, Z.-Z.3
-
25
-
-
34548126512
-
RIG-I family RNA helicases: Cytoplasmic sensor for antiviral innate immunity
-
Yoneyama M, Fujita T. RIG-I family RNA helicases: Cytoplasmic sensor for antiviral innate immunity. Cytokine Growth Factor Rev, 2007, 18: 545-551.
-
(2007)
Cytokine Growth Factor Rev
, vol.18
, pp. 545-551
-
-
Yoneyama, M.1
Fujita, T.2
-
26
-
-
39149107423
-
MDA5/RIG-I and virus recognition
-
Takeuchi O, Akira S. MDA5/RIG-I and virus recognition. Curr Opin Immunol, 2008, 20: 17-22.
-
(2008)
Curr Opin Immunol
, vol.20
, pp. 17-22
-
-
Takeuchi, O.1
Akira, S.2
-
27
-
-
33947206046
-
Cutting edge: Influenza A virus activates TLR3-dependent inflammatory and RIG-I-dependent antiviral responses in human lung epithelial cells
-
Le Goffic R, Pothlichet J, Vitour D, et al. Cutting edge: Influenza A virus activates TLR3-dependent inflammatory and RIG-I-dependent antiviral responses in human lung epithelial cells. J Immunol, 2007, 178: 3368-3372.
-
(2007)
J Immunol
, vol.178
, pp. 3368-3372
-
-
Le Goffic, R.1
Pothlichet, J.2
Vitour, D.3
-
28
-
-
33748192461
-
Retinoic acid inducible gene-I and mda-5 are involved in influenza A virus-induced expression of antiviral cytokines
-
Siren J, Imaizumi T, Sarkar D, et al. Retinoic acid inducible gene-I and mda-5 are involved in influenza A virus-induced expression of antiviral cytokines. Microbes Infect, 2006, 8: 2013-2020.
-
(2006)
Microbes Infect
, vol.8
, pp. 2013-2020
-
-
Siren, J.1
Imaizumi, T.2
Sarkar, D.3
-
29
-
-
33645214581
-
Tumor necrosis factor alpha enhances influenza A virus-induced expression of antiviral cytokines by activating RIG-I gene expression
-
Matikainen S, Siren J, Tissari J, et al. Tumor necrosis factor alpha enhances influenza A virus-induced expression of antiviral cytokines by activating RIG-I gene expression. J Virol, 2006, 80: 3515-3522.
-
(2006)
J Virol
, vol.80
, pp. 3515-3522
-
-
Matikainen, S.1
Siren, J.2
Tissari, J.3
-
30
-
-
54449099369
-
The multifunctional NS1 protein of influenza A viruses
-
Hale B G, Randall R E, Ortin J, et al. The multifunctional NS1 protein of influenza A viruses. J Gen Virol, 2008, 89: 2359-2376.
-
(2008)
J Gen Virol
, vol.89
, pp. 2359-2376
-
-
Hale, B.G.1
Randall, R.E.2
Ortin, J.3
-
31
-
-
0033870894
-
Activation of interferon regulatory factor 3 is inhibited by the influenza A virus NS1 protein
-
Talon J, Horvath C M, Polley R, et al. Activation of interferon regulatory factor 3 is inhibited by the influenza A virus NS1 protein. J Virol, 2000, 74: 7989-7996.
-
(2000)
J Virol
, vol.74
, pp. 7989-7996
-
-
Talon, J.1
Horvath, C.M.2
Polley, R.3
-
32
-
-
72949109523
-
Interplay between influenza A virus and the innate immune signaling
-
Ehrhardt C, Seyer R, Hrincius E R, et al. Interplay between influenza A virus and the innate immune signaling. Microbes Infect, 2010, 12: 81-87.
-
(2010)
Microbes Infect
, vol.12
, pp. 81-87
-
-
Ehrhardt, C.1
Seyer, R.2
Hrincius, E.R.3
-
33
-
-
33847670199
-
NS1 protein of influenza A virus inhibits the function of intracytoplasmic pathogen sensor, RIG-I
-
Guo Z, Chen L M, Zeng H, et al. NS1 protein of influenza A virus inhibits the function of intracytoplasmic pathogen sensor, RIG-I. Am J Respir Cell Mol Biol, 2007, 36: 263-269.
-
(2007)
Am J Respir Cell Mol Biol
, vol.36
, pp. 263-269
-
-
Guo, Z.1
Chen, L.M.2
Zeng, H.3
-
34
-
-
33846061693
-
Inhibition of retinoic acid-inducible gene I-mediated induction of beta interferon by the NS1 protein of influenza A virus
-
Mibayashi M, Martinez-Sobrido L, Loo Y M, et al. Inhibition of retinoic acid-inducible gene I-mediated induction of beta interferon by the NS1 protein of influenza A virus. J Virol, 2007, 81: 514-524.
-
(2007)
J Virol
, vol.81
, pp. 514-524
-
-
Mibayashi, M.1
Martinez-Sobrido, L.2
Loo, Y.M.3
-
35
-
-
33947171000
-
IFNbeta induction by influenza A virus is mediated by RIG-I which is regulated by the viral NS1 protein
-
Opitz B, Rejaibi A, Dauber B, et al. IFNbeta induction by influenza A virus is mediated by RIG-I which is regulated by the viral NS1 protein. Cell Microbiol, 2007, 9: 930-938.
-
(2007)
Cell Microbiol
, vol.9
, pp. 930-938
-
-
Opitz, B.1
Rejaibi, A.2
Dauber, B.3
-
36
-
-
65549164536
-
Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I
-
Gack M U, Albrecht R A, Urano T, et al. Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I. Cell Host Microbe, 2009, 5: 439-449.
-
(2009)
Cell Host Microbe
, vol.5
, pp. 439-449
-
-
Gack, M.U.1
Albrecht, R.A.2
Urano, T.3
-
37
-
-
0032086357
-
Influenza virus NS1 protein interacts with the cellular 30 kDa subunit of CPSF and inhibits 3′ end formation of cellular pre-mRNAs
-
Nemeroff M E, Barabino S M L, Li Y, et al. Influenza virus NS1 protein interacts with the cellular 30 kDa subunit of CPSF and inhibits 3′ end formation of cellular pre-mRNAs. Mol Cell, 1998, 1: 991-1000.
-
(1998)
Mol Cell
, vol.1
, pp. 991-1000
-
-
Nemeroff, M.E.1
Barabino, S.M.L.2
Li, Y.3
-
38
-
-
34848897191
-
Influenza A virus PB1-F2: A small protein with a big punch
-
Conenello G M, Palese P. Influenza A virus PB1-F2: A small protein with a big punch. Cell Host Microbe, 2007, 2: 207-209.
-
(2007)
Cell Host Microbe
, vol.2
, pp. 207-209
-
-
Conenello, G.M.1
Palese, P.2
-
39
-
-
70350736558
-
Phosphorylation of the influenza A virus protein PB1-F2 by PKC is crucial for apoptosis promoting functions in monocytes
-
Mitzner D, Dudek S E, Studtrucker N, et al. Phosphorylation of the influenza A virus protein PB1-F2 by PKC is crucial for apoptosis promoting functions in monocytes. Cell Microbiol, 2009, 11: 1502-1516.
-
(2009)
Cell Microbiol
, vol.11
, pp. 1502-1516
-
-
Mitzner, D.1
Dudek, S.E.2
Studtrucker, N.3
-
40
-
-
77951059450
-
Influenza virus PB1-F2 protein induces cell death through mitochondrial ANT3 and VDAC1
-
Zamarin D, Garcia-Sastre A, Xiao X, et al. Influenza virus PB1-F2 protein induces cell death through mitochondrial ANT3 and VDAC1. PLoS Pathog, 2005, 1: e4.
-
(2005)
PLoS Pathog
, vol.1
-
-
Zamarin, D.1
Garcia-Sastre, A.2
Xiao, X.3
-
41
-
-
34848926238
-
Expression of the 1918 influenza A virus PB1-F2 enhances the pathogenesis of viral and secondary bacterial pneumonia
-
McAuley J L, Hornung F, Boyd K L, et al. Expression of the 1918 influenza A virus PB1-F2 enhances the pathogenesis of viral and secondary bacterial pneumonia. Cell Host Microbe, 2007, 2: 240-249.
-
(2007)
Cell Host Microbe
, vol.2
, pp. 240-249
-
-
McAuley, J.L.1
Hornung, F.2
Boyd, K.L.3
-
42
-
-
33746858906
-
Influenza A virus PB1-F2 protein contributes to viral pathogenesis in mice
-
Zamarin D, Ortigoza M B, Palese P. Influenza A virus PB1-F2 protein contributes to viral pathogenesis in mice. J Virol, 2006, 80: 7976-7983.
-
(2006)
J Virol
, vol.80
, pp. 7976-7983
-
-
Zamarin, D.1
Ortigoza, M.B.2
Palese, P.3
-
43
-
-
34250783318
-
Acetylsalicylic acid (ASA) blocks influenza virus propagation via its NF-kB-inhibiting activity
-
Mazur I, Wurzer W J, Ehrhardt C, et al. Acetylsalicylic acid (ASA) blocks influenza virus propagation via its NF-kB-inhibiting activity. Cell Microbiol, 2007, 9: 1683-1694.
-
(2007)
Cell Microbiol
, vol.9
, pp. 1683-1694
-
-
Mazur, I.1
Wurzer, W.J.2
Ehrhardt, C.3
-
44
-
-
0032209522
-
Signaling through protein kinase C
-
Toker A. Signaling through protein kinase C. Front Biosci, 1998, 3: D1134-1147.
-
(1998)
Front Biosci
, vol.3
-
-
Toker, A.1
-
45
-
-
53249140699
-
Modulation of influenza virus replication by alteration of sodium ion transport and protein kinase C activity
-
Hoffmann H H, Palese P, Shaw M L. Modulation of influenza virus replication by alteration of sodium ion transport and protein kinase C activity. Antiviral Res, 2008, 80: 124-134.
-
(2008)
Antiviral Res
, vol.80
, pp. 124-134
-
-
Hoffmann, H.H.1
Palese, P.2
Shaw, M.L.3
-
47
-
-
70350524014
-
Influenza virus M2 protein inhibits epithelial sodium channels by increasing reactive oxygen species
-
Lazrak A, Iles K E, Liu G, et al. Influenza virus M2 protein inhibits epithelial sodium channels by increasing reactive oxygen species. FASEB J, 2009, 23: 3829-3842.
-
(2009)
FASEB J
, vol.23
, pp. 3829-3842
-
-
Lazrak, A.1
Iles, K.E.2
Liu, G.3
-
48
-
-
23844500631
-
Characterization of the host cell entry of filamentous influenza virus
-
Sieczkarski S B, Whittaker G R. Characterization of the host cell entry of filamentous influenza virus. Arch Virol, 2005, 150: 1783-1796.
-
(2005)
Arch Virol
, vol.150
, pp. 1783-1796
-
-
Sieczkarski, S.B.1
Whittaker, G.R.2
-
49
-
-
0025943243
-
Effects of protein kinase C inhibitors on viral entry and infectivity
-
Constantinescu S N, Cernescu C D, Popescu L M. Effects of protein kinase C inhibitors on viral entry and infectivity. FEBS Lett, 1991, 292: 31-33.
-
(1991)
FEBS Lett
, vol.292
, pp. 31-33
-
-
Constantinescu, S.N.1
Cernescu, C.D.2
Popescu, L.M.3
-
50
-
-
0031758998
-
Influenza virus hemagglutinin stimulates the protein kinase C activity of human polymorphonuclear leucocytes
-
Arora D J, Gasse N. Influenza virus hemagglutinin stimulates the protein kinase C activity of human polymorphonuclear leucocytes. Arch Virol, 1998, 143: 2029-2037.
-
(1998)
Arch Virol
, vol.143
, pp. 2029-2037
-
-
Arora, D.J.1
Gasse, N.2
-
51
-
-
0033767394
-
Entry of influenza viruses into cells is inhibited by a highly specific protein kinase C inhibitor
-
Root C N, Wills E G, McNair L L, et al. Entry of influenza viruses into cells is inhibited by a highly specific protein kinase C inhibitor. J Gen Virol, 2000, 81: 2697-2705.
-
(2000)
J Gen Virol
, vol.81
, pp. 2697-2705
-
-
Root, C.N.1
Wills, E.G.2
McNair, L.L.3
-
52
-
-
0037213578
-
Role of protein kinase C betaII in influenza virus entry via late endosomes
-
Sieczkarski S B, Brown H A, Whittaker G R. Role of protein kinase C betaII in influenza virus entry via late endosomes. J Virol, 2003, 77: 460-469.
-
(2003)
J Virol
, vol.77
, pp. 460-469
-
-
Sieczkarski, S.B.1
Brown, H.A.2
Whittaker, G.R.3
-
53
-
-
54049131196
-
RNA viruses and the mitogenic Raf/MEK/ERK signal transduction cascade
-
Pleschka S. RNA viruses and the mitogenic Raf/MEK/ERK signal transduction cascade. Biol Chem, 2008, 389: 1273-1282.
-
(2008)
Biol Chem
, vol.389
, pp. 1273-1282
-
-
Pleschka, S.1
-
54
-
-
0035450255
-
Effect of influenza virus matrix protein and viral RNA on ribonucleoprotein formation and nuclear export
-
Huang X, Liu T, Muller J, et al. Effect of influenza virus matrix protein and viral RNA on ribonucleoprotein formation and nuclear export. Virology, 2001, 287: 405-416.
-
(2001)
Virology
, vol.287
, pp. 405-416
-
-
Huang, X.1
Liu, T.2
Muller, J.3
-
55
-
-
0037440711
-
Nuclear export of influenza viral ribonucleoprotein is temperature-dependently inhibited by dissociation of viral matrix protein
-
Sakaguchi A, Hirayama E, Hiraki A, et al. Nuclear export of influenza viral ribonucleoprotein is temperature-dependently inhibited by dissociation of viral matrix protein. Virology, 2003, 306: 244-253.
-
(2003)
Virology
, vol.306
, pp. 244-253
-
-
Sakaguchi, A.1
Hirayama, E.2
Hiraki, A.3
-
56
-
-
1542358150
-
MEK inhibition impairs influenza B virus propagation without emergence of resistant variants
-
Ludwig S, Wolff T, Ehrhardt C, et al. MEK inhibition impairs influenza B virus propagation without emergence of resistant variants. FEBS Letters, 2004, 561: 37-43.
-
(2004)
FEBS Letters
, vol.561
, pp. 37-43
-
-
Ludwig, S.1
Wolff, T.2
Ehrhardt, C.3
-
57
-
-
0035090589
-
Influenza virus propagation is impaired by inhibition of the Raf/MEK/ERK signalling cascade
-
Pleschka S, Wolff T, Ehrhardt C, et al. Influenza virus propagation is impaired by inhibition of the Raf/MEK/ERK signalling cascade. Nat Cell Biol, 2001, 3: 301-305.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 301-305
-
-
Pleschka, S.1
Wolff, T.2
Ehrhardt, C.3
-
58
-
-
33745186230
-
Membrane accumulation of influenza A virus hemagglutinin triggers nuclear export of the viral genome via protein kinase Calpha-mediated activation of ERK signaling
-
Marjuki H, Alam M I, Ehrhardt C, et al. Membrane accumulation of influenza A virus hemagglutinin triggers nuclear export of the viral genome via protein kinase Calpha-mediated activation of ERK signaling. J Biol Chem, 2006, 281: 16707-16715.
-
(2006)
J Biol Chem
, vol.281
, pp. 16707-16715
-
-
Marjuki, H.1
Alam, M.I.2
Ehrhardt, C.3
-
59
-
-
38849122079
-
Higher polymerase activity of a human influenza virus enhances activation of the hemagglutinin-induced Raf/MEK/ERK signal cascade
-
Marjuki H, Yen H L, Franks J, et al. Higher polymerase activity of a human influenza virus enhances activation of the hemagglutinin-induced Raf/MEK/ERK signal cascade. Virol J, 2007, 4: 134.
-
(2007)
Virol J
, vol.4
, pp. 134
-
-
Marjuki, H.1
Yen, H.L.2
Franks, J.3
-
60
-
-
0019850995
-
Selected host cell capped RNA fragments prime influenza viral RNA transcription in vivo
-
Beaton A R, Krug R M. Selected host cell capped RNA fragments prime influenza viral RNA transcription in vivo. Nucleic Acids Res, 1981, 9: 4423-4436.
-
(1981)
Nucleic Acids Res
, vol.9
, pp. 4423-4436
-
-
Beaton, A.R.1
Krug, R.M.2
-
61
-
-
0019343607
-
Priming of influenza viral RNA transcription by capped heterologous RNAs
-
Krug R M. Priming of influenza viral RNA transcription by capped heterologous RNAs. Curr Top Microbiol Immunol, 1981, 93: 125-149.
-
(1981)
Curr Top Microbiol Immunol
, vol.93
, pp. 125-149
-
-
Krug, R.M.1
-
62
-
-
0033560753
-
Influenza A virus NS1 protein targetspoly(A)-binding protein II of the cellular 3[prime]-end processing machinery
-
Chen Z, Li Y, Krug R M. Influenza A virus NS1 protein targetspoly(A)-binding protein II of the cellular 3[prime]-end processing machinery. EMBO J, 1999, 18: 2273-2283.
-
(1999)
EMBO J
, vol.18
, pp. 2273-2283
-
-
Chen, Z.1
Li, Y.2
Krug, R.M.3
-
63
-
-
0028040760
-
The influenza virus NS1 protein: a novel inhibitor of pre-mRNA splicing
-
Lu Y, Qian X Y, Krug R M. The influenza virus NS1 protein: a novel inhibitor of pre-mRNA splicing. Genes Dev, 1994, 8: 1817-1828.
-
(1994)
Genes Dev
, vol.8
, pp. 1817-1828
-
-
Lu, Y.1
Qian, X.Y.2
Krug, R.M.3
-
64
-
-
0027518202
-
Translational control by influenza virus. Selective translation is mediated by sequences within the viral mRNA 5′-untranslated region
-
Garfinkel M S, Katze M G. Translational control by influenza virus. Selective translation is mediated by sequences within the viral mRNA 5′-untranslated region. J Biol Chem, 1993, 268: 22223-22226.
-
(1993)
J Biol Chem
, vol.268
, pp. 22223-22226
-
-
Garfinkel, M.S.1
Katze, M.G.2
-
65
-
-
0028923921
-
Influenza virus NS1 protein enhances the rate of translation initiation of viral mRNAs
-
de la Luna S, Fortes P, Beloso A, et al. Influenza virus NS1 protein enhances the rate of translation initiation of viral mRNAs. J Virol, 1995, 69: 2427-2433.
-
(1995)
J Virol
, vol.69
, pp. 2427-2433
-
-
de la Luna, S.1
Fortes, P.2
Beloso, A.3
-
66
-
-
0028055149
-
Influenza virus NS1 protein stimulates translation of the M1 protein
-
Enami K, Sato T A, Nakada S, et al. Influenza virus NS1 protein stimulates translation of the M1 protein. J Virol, 1994, 68: 1432-1437.
-
(1994)
J Virol
, vol.68
, pp. 1432-1437
-
-
Enami, K.1
Sato, T.A.2
Nakada, S.3
-
67
-
-
0022976677
-
Cellular mRNA translation is blocked at both initiation and elongation after infection by influenza virus or adenovirus
-
Katze M G, DeCorato D, Krug R M. Cellular mRNA translation is blocked at both initiation and elongation after infection by influenza virus or adenovirus. J Virol, 1986, 60: 1027-1039.
-
(1986)
J Virol
, vol.60
, pp. 1027-1039
-
-
Katze, M.G.1
Decorato, D.2
Krug, R.M.3
-
68
-
-
0028880783
-
Translational control by influenza virus. Identification of cis-acting sequences and trans-acting factors which may regulate selective viral mRNA translation
-
Park Y W, Katze M G. Translational control by influenza virus. Identification of cis-acting sequences and trans-acting factors which may regulate selective viral mRNA translation. J Biol Chem, 1995, 270: 28433-28439.
-
(1995)
J Biol Chem
, vol.270
, pp. 28433-28439
-
-
Park, Y.W.1
Katze, M.G.2
-
69
-
-
0033838456
-
Eukaryotic translation initiation factor 4GI is a cellular target for NS1 protein, a translational activator of influenza virus
-
Aragon T, de la Luna S, Novoa I, et al. Eukaryotic translation initiation factor 4GI is a cellular target for NS1 protein, a translational activator of influenza virus. Mol Cell Biol, 2000, 20: 6259-6268.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 6259-6268
-
-
Aragon, T.1
de la Luna, S.2
Novoa, I.3
-
70
-
-
0346121589
-
PABP1 and eIF4GI associate with influenza virus NS1 protein in viral mRNA translation initiation complexes
-
Burgui I, Aragon T, Ortin J, et al. PABP1 and eIF4GI associate with influenza virus NS1 protein in viral mRNA translation initiation complexes. J Gen Virol, 2003, 84: 3263-3274.
-
(2003)
J Gen Virol
, vol.84
, pp. 3263-3274
-
-
Burgui, I.1
Aragon, T.2
Ortin, J.3
-
71
-
-
0027252545
-
Modification of eukaryotic initiation factor 4F during infection by influenza virus
-
Feigenblum D, Schneider R J. Modification of eukaryotic initiation factor 4F during infection by influenza virus. J Virol, 1993, 67: 3027-3035.
-
(1993)
J Virol
, vol.67
, pp. 3027-3035
-
-
Feigenblum, D.1
Schneider, R.J.2
-
72
-
-
0028815704
-
Regulation of the interferon-induced PKR: can viruses cope?
-
Katze M G. Regulation of the interferon-induced PKR: can viruses cope? Trends in Microbiology, 1995, 3: 75-78.
-
(1995)
Trends in Microbiology
, vol.3
, pp. 75-78
-
-
Katze, M.G.1
-
73
-
-
33847177628
-
The cellular protein P58IPK regulates influenza virus mRNA translation and replication through a PKR-Mediated mechanism
-
Goodman A G, Smith J A, Balachandran S, et al. The cellular protein P58IPK regulates influenza virus mRNA translation and replication through a PKR-Mediated mechanism. J Virol, 2007, 81: 2221-2230.
-
(2007)
J Virol
, vol.81
, pp. 2221-2230
-
-
Goodman, A.G.1
Smith, J.A.2
Balachandran, S.3
-
74
-
-
0024535928
-
Control of influenza virus gene expression: quantitative analysis of each viral RNA species in infected cells
-
Hatada E, Hasegawa M, Mukaigawa J, et al. Control of influenza virus gene expression: quantitative analysis of each viral RNA species in infected cells. J Biochem, 1989, 105: 537-546.
-
(1989)
J Biochem
, vol.105
, pp. 537-546
-
-
Hatada, E.1
Hasegawa, M.2
Mukaigawa, J.3
-
75
-
-
0023155247
-
Influenza virus gene expression: control mechanisms at early and late times of infection and nuclearcytoplasmic transport of virus-specific RNAs
-
Shapiro G I, Gurney T, Jr Krug R M. Influenza virus gene expression: control mechanisms at early and late times of infection and nuclearcytoplasmic transport of virus-specific RNAs. J Virol, 1987, 61: 764-773.
-
(1987)
J Virol
, vol.61
, pp. 764-773
-
-
Shapiro, G.I.1
Gurney Jr., T.2
Krug, R.M.3
-
76
-
-
0025984455
-
Temporal control for translation of influenza virus mRNAs
-
Yamanaka K, Nagata K, Ishihama A. Temporal control for translation of influenza virus mRNAs. Arch Virol, 1991, 120: 33-42.
-
(1991)
Arch Virol
, vol.120
, pp. 33-42
-
-
Yamanaka, K.1
Nagata, K.2
Ishihama, A.3
-
77
-
-
58149175555
-
The life of a cell: apoptosis regulation by the PI3K/PKB pathway
-
Duronio V. The life of a cell: apoptosis regulation by the PI3K/PKB pathway. Biochem J, 2008, 415: 333-344.
-
(2008)
Biochem J
, vol.415
, pp. 333-344
-
-
Duronio, V.1
-
78
-
-
1642471831
-
PI3K/Akt and apoptosis: size matters
-
Franke T F, Hornik C P, Segev L, et al. PI3K/Akt and apoptosis: size matters. Oncogene, 2003, 22: 8983-8998.
-
(2003)
Oncogene
, vol.22
, pp. 8983-8998
-
-
Franke, T.F.1
Hornik, C.P.2
Segev, L.3
-
79
-
-
58149129203
-
PI3K-Akt signaling and viral infection
-
Ji W T, Liu H J. PI3K-Akt signaling and viral infection. Recent Pat Biotechnol, 2008, 2: 218-226.
-
(2008)
Recent Pat Biotechnol
, vol.2
, pp. 218-226
-
-
Ji, W.T.1
Liu, H.J.2
-
80
-
-
38349136199
-
Binding of influenza A virus NS1 protein to the inter-SH2 domain of p85 suggests a novel mechanism for phosphoinositide 3-kinase activation
-
Hale B G, Batty I H, Downes C P, et al. Binding of influenza A virus NS1 protein to the inter-SH2 domain of p85 suggests a novel mechanism for phosphoinositide 3-kinase activation. J Biol Chem, 2008, 283: 1372-1380.
-
(2008)
J Biol Chem
, vol.283
, pp. 1372-1380
-
-
Hale, B.G.1
Batty, I.H.2
Downes, C.P.3
-
81
-
-
33749004778
-
Influenza A virus NS1 protein binds p85beta and activates phosphatidylinositol-3-kinase signaling
-
Hale B G, Jackson D, Chen Y H, et al. Influenza A virus NS1 protein binds p85beta and activates phosphatidylinositol-3-kinase signaling. Proc Natl Acad Sci USA, 2006, 103: 14194-14199.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 14194-14199
-
-
Hale, B.G.1
Jackson, D.2
Chen, Y.H.3
-
82
-
-
34247105759
-
PI3K signalling during influenza A virus infections
-
Hale B G, Randall R E. PI3K signalling during influenza A virus infections. Biochem Soc Trans, 2007, 35: 186-187.
-
(2007)
Biochem Soc Trans
, vol.35
, pp. 186-187
-
-
Hale, B.G.1
Randall, R.E.2
-
83
-
-
36349018937
-
SH3 binding motif 1 in influenza A virus NS1 protein is essential for PI3K/Akt signaling pathway activation
-
Shin Y K, Li Y, Liu Q, et al. SH3 binding motif 1 in influenza A virus NS1 protein is essential for PI3K/Akt signaling pathway activation. J Virol, 2007, 81: 12730-12739.
-
(2007)
J Virol
, vol.81
, pp. 12730-12739
-
-
Shin, Y.K.1
Li, Y.2
Liu, Q.3
-
84
-
-
33846160497
-
Influenza A virus NS1 protein activates the phosphatidylinositol 3-kinase (PI3K)/Akt pathway by direct interaction with the p85 subunit of PI3K
-
Shin Y K, Liu Q, Tikoo S K, et al. Influenza A virus NS1 protein activates the phosphatidylinositol 3-kinase (PI3K)/Akt pathway by direct interaction with the p85 subunit of PI3K. J Gen Virol, 2007, 88: 13-18.
-
(2007)
J Gen Virol
, vol.88
, pp. 13-18
-
-
Shin, Y.K.1
Liu, Q.2
Tikoo, S.K.3
-
85
-
-
33947381763
-
Influenza A virus NS1 protein activates the PI3K/Akt pathway to mediate antiapoptotic signaling responses
-
Ehrhardt C, Wolff T, Pleschka S, et al. Influenza A virus NS1 protein activates the PI3K/Akt pathway to mediate antiapoptotic signaling responses. J Virol, 2007, 81: 3058-3067.
-
(2007)
J Virol
, vol.81
, pp. 3058-3067
-
-
Ehrhardt, C.1
Wolff, T.2
Pleschka, S.3
-
86
-
-
34250828457
-
Control of apoptosis in influenza virus-infected cells by up-regulation of Akt and p53 signaling
-
Zhirnov O P, Klenk H D. Control of apoptosis in influenza virus-infected cells by up-regulation of Akt and p53 signaling. Apoptosis, 2007, 12: 1419-1432.
-
(2007)
Apoptosis
, vol.12
, pp. 1419-1432
-
-
Zhirnov, O.P.1
Klenk, H.D.2
-
87
-
-
77952701390
-
The PI3K/Akt pathway inhibits influenza A virus-induced Bax-mediated apoptosis by negatively regulating the JNK pathway via ASK1
-
Lu X Y, Masic A, Li Y, et al. The PI3K/Akt pathway inhibits influenza A virus-induced Bax-mediated apoptosis by negatively regulating the JNK pathway via ASK1. J Gen Virol, 2010, 91: 1439-1449.
-
(2010)
J Gen Virol
, vol.91
, pp. 1439-1449
-
-
Lu, X.Y.1
Masic, A.2
Li, Y.3
-
88
-
-
65549130101
-
A new player in a deadly game: influenza viruses and the PI3K/Akt signalling pathway
-
Ehrhardt C, Ludwig S. A new player in a deadly game: influenza viruses and the PI3K/Akt signalling pathway. Cell Microbiol, 2009, 11: 863-871.
-
(2009)
Cell Microbiol
, vol.11
, pp. 863-871
-
-
Ehrhardt, C.1
Ludwig, S.2
-
89
-
-
33745753573
-
Bivalent role of the phosphatidylinositol-3-kinase (PI3K) during influenza virus infection and host cell defence
-
Ehrhardt C, Marjuki H, Wolff T, et al. Bivalent role of the phosphatidylinositol-3-kinase (PI3K) during influenza virus infection and host cell defence. Cell Microbiol, 2006, 8: 1336-1348.
-
(2006)
Cell Microbiol
, vol.8
, pp. 1336-1348
-
-
Ehrhardt, C.1
Marjuki, H.2
Wolff, T.3
-
90
-
-
33847644660
-
Effect of the phosphatidylinositol 3-kinase/Akt pathway on influenza A virus propagation
-
Shin Y K, Liu Q, Tikoo S K, et al. Effect of the phosphatidylinositol 3-kinase/Akt pathway on influenza A virus propagation. J Gen Virol, 2007, 88: 942-950.
-
(2007)
J Gen Virol
, vol.88
, pp. 942-950
-
-
Shin, Y.K.1
Liu, Q.2
Tikoo, S.K.3
-
91
-
-
0034708454
-
Influenza virus-induced NF-kappaB-dependent gene expression is mediated by overexpression of viral proteins and involves oxidative radicals and activation of IkappaB kinase
-
Flory E, Kunz M, Scheller C, et al. Influenza virus-induced NF-kappaB-dependent gene expression is mediated by overexpression of viral proteins and involves oxidative radicals and activation of IkappaB kinase. J Biol Chem, 2000, 275: 8307-8314.
-
(2000)
J Biol Chem
, vol.275
, pp. 8307-8314
-
-
Flory, E.1
Kunz, M.2
Scheller, C.3
-
92
-
-
33847687659
-
Multiple functions of the IKK-related kinase IKKepsilon in interferon-mediated antiviral immunity
-
Tenoever B R, Ng S L, Chua M A, et al. Multiple functions of the IKK-related kinase IKKepsilon in interferon-mediated antiviral immunity. Science, 2007, 315: 1274-1278.
-
(2007)
Science
, vol.315
, pp. 1274-1278
-
-
Tenoever, B.R.1
Ng, S.L.2
Chua, M.A.3
-
93
-
-
0028797157
-
Expression of influenza virus hemagglutinin activates transcription factor NF-kappa B
-
Pahl H L, Baeuerle P A. Expression of influenza virus hemagglutinin activates transcription factor NF-kappa B. J Virol, 1995, 69: 1480-1484.
-
(1995)
J Virol
, vol.69
, pp. 1480-1484
-
-
Pahl, H.L.1
Baeuerle, P.A.2
-
94
-
-
0037975504
-
Double-stranded RNA induces the synthesis of specific chemokines by bronchial epithelial cells
-
Gern J E, French D A, Grindle K A, et al. Double-stranded RNA induces the synthesis of specific chemokines by bronchial epithelial cells. Am J Respir Cell Mol Biol, 2003, 28: 731-737.
-
(2003)
Am J Respir Cell Mol Biol
, vol.28
, pp. 731-737
-
-
Gern, J.E.1
French, D.A.2
Grindle, K.A.3
-
95
-
-
38449122497
-
TLR-mediated activation of type I IFN during antiviral immune responses: fighting the battle to win the war
-
Severa M, Fitzgerald K A. TLR-mediated activation of type I IFN during antiviral immune responses: fighting the battle to win the war. Curr Top Microbiol Immunol, 2007, 316: 167-192.
-
(2007)
Curr Top Microbiol Immunol
, vol.316
, pp. 167-192
-
-
Severa, M.1
Fitzgerald, K.A.2
-
96
-
-
4043118343
-
Active NF-kappaB signalling is a prerequisite for influenza virus infection
-
Nimmerjahn F, Dudziak D, Dirmeier U, et al. Active NF-kappaB signalling is a prerequisite for influenza virus infection. J Gen Virol, 2004, 85: 2347-2356.
-
(2004)
J Gen Virol
, vol.85
, pp. 2347-2356
-
-
Nimmerjahn, F.1
Dudziak, D.2
Dirmeier, U.3
-
97
-
-
53749106185
-
NF-kappaB signaling differentially regulates influenza virus RNA synthesis
-
Kumar N, Xin Z T, Liang Y, et al. NF-kappaB signaling differentially regulates influenza virus RNA synthesis. J Virol, 2008, 82: 9880-9889.
-
(2008)
J Virol
, vol.82
, pp. 9880-9889
-
-
Kumar, N.1
Xin, Z.T.2
Liang, Y.3
-
98
-
-
3843130838
-
NF-kappaB-dependent induction of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and Fas/FasL is crucial for efficient influenza virus propagation
-
Wurzer W J, Ehrhardt C, Pleschka S, et al. NF-kappaB-dependent induction of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and Fas/FasL is crucial for efficient influenza virus propagation. J Biol Chem, 2004, 279: 30931-30937.
-
(2004)
J Biol Chem
, vol.279
, pp. 30931-30937
-
-
Wurzer, W.J.1
Ehrhardt, C.2
Pleschka, S.3
-
99
-
-
33748171464
-
The interferon-inducible RNA helicase, mda-5, is involved in measles virus-induced expression of antiviral cytokines
-
Berghall H, Siren J, Sarkar D, et al. The interferon-inducible RNA helicase, mda-5, is involved in measles virus-induced expression of antiviral cytokines. Microbes Infection, 2006, 8: 2138-2144.
-
(2006)
Microbes Infection
, vol.8
, pp. 2138-2144
-
-
Berghall, H.1
Siren, J.2
Sarkar, D.3
-
100
-
-
33846554134
-
Retinoic acid-inducible gene I mediates early antiviral response and Toll-like receptor 3 expression in respiratory syncytial virus-infected airway epithelial cells
-
Liu P, Jamaluddin M, Li K, et al. Retinoic acid-inducible gene I mediates early antiviral response and Toll-like receptor 3 expression in respiratory syncytial virus-infected airway epithelial cells. J Virol, 2007, 81: 1401-1411.
-
(2007)
J Virol
, vol.81
, pp. 1401-1411
-
-
Liu, P.1
Jamaluddin, M.2
Li, K.3
-
101
-
-
34548418935
-
Toll-like receptors, RIG-I-like RNA helicases and the antiviral innate immune response
-
Thompson A J, Locarnini S A. Toll-like receptors, RIG-I-like RNA helicases and the antiviral innate immune response. Immunol Cell Biol, 2007, 85: 435-445.
-
(2007)
Immunol Cell Biol
, vol.85
, pp. 435-445
-
-
Thompson, A.J.1
Locarnini, S.A.2
-
102
-
-
42149119018
-
Cutting edge: innate immune response triggered by influenza A virus is negatively regulated by SOCS1 and SOCS3 through a RIG-I/IFNAR1-dependent pathway
-
Pothlichet J, Chignard M, Si-Tahar M. Cutting edge: innate immune response triggered by influenza A virus is negatively regulated by SOCS1 and SOCS3 through a RIG-I/IFNAR1-dependent pathway. J Immunol, 2008, 180: 2034-2038.
-
(2008)
J Immunol
, vol.180
, pp. 2034-2038
-
-
Pothlichet, J.1
Chignard, M.2
Si-Tahar, M.3
-
103
-
-
40749162423
-
Cytosolic antiviral RNA recognition pathway activates caspases 1 and 3
-
Rintahaka J, Wiik D, Kovanen P E, et al. Cytosolic antiviral RNA recognition pathway activates caspases 1 and 3. J Immunol, 2008, 180: 1749-1757.
-
(2008)
J Immunol
, vol.180
, pp. 1749-1757
-
-
Rintahaka, J.1
Wiik, D.2
Kovanen, P.E.3
-
104
-
-
76749090540
-
Genome-wide RNAi screen identifies human host factors crucial for influenza virus replication
-
Karlas A, Machuy N, Shin Y, et al. Genome-wide RNAi screen identifies human host factors crucial for influenza virus replication. Nature, 2010, 463: 818-822.
-
(2010)
Nature
, vol.463
, pp. 818-822
-
-
Karlas, A.1
Machuy, N.2
Shin, Y.3
-
105
-
-
76749108989
-
Human host factors required for influenza virus replication
-
Konig R, Stertz S, Zhou Y, et al. Human host factors required for influenza virus replication. Nature, 2010, 463: 813-817.
-
(2010)
Nature
, vol.463
, pp. 813-817
-
-
Konig, R.1
Stertz, S.2
Zhou, Y.3
|