Exploring the structural and functional effect of pRB by significant nsSNP in the coding region of RB1 gene causing retinoblastoma

Science China Life Sciences

Volumn 53, Issue 2, 2010, Pages 234-240

  Rajasekaran, R ^a   Sethumadhavan, Rao ^a  

^a VIT UNIVERSITY   (India)

Author keywords

E2F 2; Non synonymous SNP; pRB; RB1 gene; Retinoblastoma

Indexed keywords

MUTANT PROTEIN; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR E2F2; PROTEIN BINDING;

ARTICLE; BIOLOGICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; HUMAN; METABOLISM; MUTATION; OPEN READING FRAME; PROTEIN BINDING; SINGLE NUCLEOTIDE POLYMORPHISM; TUMOR SUPPRESSOR GENE;

E2F2 TRANSCRIPTION FACTOR; GENES, RETINOBLASTOMA; HUMANS; MODELS, BIOLOGICAL; MODELS, MOLECULAR; MOLECULAR STRUCTURE; MUTANT PROTEINS; MUTATION; OPEN READING FRAMES; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN BINDING; RETINOBLASTOMA PROTEIN;

EID: 77949310557     PISSN: 16747305     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11427-010-0039-y     Document Type: Article

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