Co-amorphous simvastatin and glipizide combinations show improved physical stability without evidence of intermolecular interactions

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 81, Issue 1, 2012, Pages 159-169

  Löbmann, Korbinian ^a   Strachan, Clare ^a   Grohganz, Holger ^b   Rades, Thomas ^a   Korhonen, Ossi ^c   Laitinen, Riikka ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c UNIVERSITY OF EASTERN FINLAND   (Finland)

Author keywords

Co amorphous; Co milling; Dissolution; Glipizide; Simvastatin; Stability

Indexed keywords

GLIPIZIDE; SIMVASTATIN;

ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; DRUG FORMULATION; DRUG MIXTURE; DRUG SOLUBILITY; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; INFRARED SPECTROSCOPY; MISCIBILITY; MOLECULAR INTERACTION; MOLECULAR MECHANICS; PHYSICAL CHEMISTRY; THERMOSTABILITY; X RAY POWDER DIFFRACTION;

DRUG COMBINATIONS; DRUG COMPOUNDING; DRUG INCOMPATIBILITY; DRUG STABILITY; GLIPIZIDE; HYPOGLYCEMIC AGENTS; HYPOLIPIDEMIC AGENTS; SIMVASTATIN; SOLUBILITY;

EID: 84861092839     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2012.02.004     Document Type: Article

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