Survival Response to Increased Ceramide Involves Metabolic Adaptation through Novel Regulators of Glycolysis and Lipolysis

PLoS Genetics

Volumn 9, Issue 6, 2013, Pages

  Nirala, Niraj K ^a   Rahman, Motiur ^a   Walls, Stanley M ^b   Singh, Alka ^a   Zhu, Lihua Julie ^a   Bamba, Takeshi ^c   Fukusaki, Eiichiro ^c   Srideshikan, Sargur M ^d   Harris, Greg L ^b   Ip, Y Tony ^a   Bodmer, Rolf ^e   Acharya, Usha R ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b SAN DIEGO STATE UNIVERSITY   (United States)

^c OSAKA UNIVERSITY   (Japan)

^d NATIONAL CANCER INSTITUTE   (United States)

^e BURNHAM INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CERAMIDE; CERAMIDE KINASE; ENOLASE; LACTATE DEHYDROGENASE; PHOSPHOGLYCERATE MUTASE; PROTEIN KINASE B; PYRUVATE KINASE; TRANSCRIPTION FACTOR FOXO; TRIACYLGLYCEROL;

ADAPTATION; AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORRELATIONAL STUDY; ENERGY CONSERVATION; ENERGY METABOLISM; ENZYME ACTIVATION; ENZYME ACTIVITY; GLYCOLYSIS; HEART DISEASE; HETEROZYGOSITY; HOMEOSTASIS; INTESTINE; LIFESPAN; LIPID ANALYSIS; LIPID METABOLISM; LIPID STORAGE; LIPOLYSIS; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PROTEIN LOCALIZATION; STARVATION; SURVIVAL RATE; TISSUE DISTRIBUTION; TRANSCRIPTION REGULATION; UPREGULATION; WILD TYPE;

ANIMALS; CERAMIDES; DROSOPHILA MELANOGASTER; ENERGY METABOLISM; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; GLYCOLYSIS; LIPOLYSIS; MICE; ONCOGENE PROTEIN V-AKT; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; STRESS, PHYSIOLOGICAL;

MAMMALIA; MUS;

EID: 84879669913     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1003556     Document Type: Article

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