Living with lethal PIP3 levels: Viability of flies lacking PTEN restored by a PH domain mutation in Akt/PKB

Science

Volumn 295, Issue 5562, 2002, Pages 2088-2091

  Stocker, Hugo ^a   Andjelkovic, Mirjana ^a   Oldham, Sean ^a   Laffargue, Muriel ^a   Wymann, Matthias P ^a   Hemmings, Brian A ^a   Hafen, Ernst ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

GENETIC ENGINEERING; MUTAGENESIS; TUMORS;

TUMORIGENESIS;

ENZYMES;

PHOSPHATASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PLECKSTRIN; POLYPHOSPHOINOSITIDE; PROTEIN KINASE B;

CANCER; GENETICS; MUTATION;

ARTICLE; CELL VIABILITY; DROSOPHILA MELANOGASTER; EFFECTOR CELL; ENZYME SPECIFICITY; FLY; GENE MUTATION; LETHALITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; RECEPTOR AFFINITY; TARGET CELL; TUMOR SUPPRESSOR GENE;

DROSOPHILA MELANOGASTER; MELANOGASTER;

EID: 0037086001     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1068094     Document Type: Article

References (46)