Targeted expression of dominant negative proteasome mutants in Drosophila melanogaster

Genesis (United States)

Volumn 34, Issue 1-2, 2002, Pages 80-82

  Belote, John M ^a   Fortier, Eric ^a  

^a SYRACUSE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MUTANT PROTEIN; PROTEASOME; UBIQUITIN;

APOPTOSIS; ARTICLE; DROSOPHILA MELANOGASTER; GENE EXPRESSION; GENE TARGETING; HETEROZYGOSITY; MISSENSE MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; TRANSGENE;

DROSOPHILA MELANOGASTER; MELANOGASTER;

EID: 0036743483     PISSN: 1526954X     EISSN: None     Source Type: Journal    
DOI: 10.1002/gene.10131     Document Type: Article

References (18)

1. Baumeister W, Walz J, Zühl F, Seemüller E. 1998. The proteasome: paradigm of a self-compartmentalizing protease. Cell 92:367-380.
2. Brand AH, Perrimon N. 1993. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118:401-415.
3. Chain DG, Schwartz JH, Hedge AN. 1999. Ubiquitin-mediated proteolysis in learning and memory. Mol Neurobiol 20:125-142.
4. Covi JA, Belote JM, Mykles DL. 1999. Subunit compositions and catalytic properties of proteasomes from developmental temperature-sensitive mutants of Drosophila melanogaster. Arch Biochem Biophys 368:85-97.
5. Freeman M. 1997. Personal communication to FlyBase available from http://flybase.bio.indiana.edu:82/.bin/fbidq.html?FBrf0091569.
6. Hampton RY, Bhakta H. 1997. Ubiquitin-mediated regulation of 3-hydroxy-3-methylglutaryl-CoA reductase. Proc Natl Acad Sci USA 94:12944-12948
7. Hershko A, Ciechanover A. 1998. The ubiquitin system. Annu Rev Biochem 67:425-479.
8. Holden JJ, Suzuki DT. 1973. Temperature-sensitive mutations in Drosophila melanogaster XII. The genetic and developmental effects of dominant lethals on chromosome 3. Genetics 73:445-458.
9. Hoyt MA. 1997. Eliminating all obstacles: regulated proteolysis in the eukaryotic cell cycle. Cell 91:149-151.
10. Huang Y, Baker RT, Fischer-Vize JA. 1995. Control of cell fate by a deubiquitinating enzyme encoded by the fat facets gene. Science 270:1828-1831.
11. Jesenberger V, Jentsch S. 2002. Deadly encounter: ubiquitin meets apoptosis. Nat Rev Mol Cell Biol 3:112-121.
12. Myung J, Kim KB, Crews CM. 2001. The ubiquitin-proteasome pathway and proteasome inhibitors. Med Res Rev 21:245-273.
13. Naidoo N, Song W, Hunter-Ensor M, Sehgal A. 1999. A role for the proteasome in the light response of the timeless clock protein. Science 285:1737-1741.
14. Saville KJ, Belote JM. 1993. Identification of an essential gene, 1(3)73Ai, with a dominant temperature-sensitive lethal allele, encoding a Drosophila proteasome subunit. Proc Natl Acad Sci USA 90:8842-8846.
15. Schweisguth F. 1999. Dominant-negative mutations in the β2 and β6 proteasome subunit genes affect alternative cell fate decisions in the Drosophila sense organ lineage. Proc Natl Acad Sci USA 96:11382-11386.
16. Smyth KA, Belote JM. 1999. The dominant temperature-sensitive lethal DTS7 of Drosophila melanogaster encodes an altered 20S proteasome beta-type subunit. Genetics 151:211-220.
17. Tsang T, Copeland V, Bowden GT. 1991. A set of cloning vectors for rapid and versatile adaptation of restriction fragments. BioTechniques 10:330.
18. Zhou MY, Clark SE, Gomez-Sanchez CE. 1995. Universal cloning method by TA strategy. BioTechniques 19:34-35.