In vitro ischemia suppresses hypoxic induction of hypoxia-inducible factor-1α by inhibition of synthesis and not enhanced degradation

Journal of Neuroscience Research

Volumn 91, Issue 8, 2013, Pages 1066-1075

  Karuppagounder, Saravanan S ^a,b   Basso, Manuela ^a,b   Sleiman, Sama F ^a,b   Ma, Thong C ^a,b   Speer, Rachel E ^a,b   Smirnova, Natalya A ^a,b   Gazaryan, Irina G ^a,b   Ratan, Rajiv R ^a,b  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b BURKE MEDICAL RESEARCH INSTITUTE   (United States)

Author keywords

HIF 1 ; Ischemia; Oxygen and glucose deprivation; Prolylhydroxylase

Indexed keywords

ADENOSINE TRIPHOSPHATE; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; DACTINOMYCIN; FIREFLY LUCIFERASE; GLUCOSE; HYBRID PROTEIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; OXYGEN; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PROTEASOME INHIBITOR; PROTOCATECHUIC ACID;

ARTICLE; BINDING SITE; BRAIN HYPOXIA; BRAIN ISCHEMIA; CELL HYPOXIA; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HYDROXYLATION; IN VITRO STUDY; NEUROBLASTOMA CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; TRANSLATION REGULATION; UBIQUITINATION;

CELL HYPOXIA; CELL LINE; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; HYPOXIA-ISCHEMIA, BRAIN; IMMUNOBLOTTING; NEURONS;

EID: 84879603441     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.23204     Document Type: Article

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