메뉴 건너뛰기




Volumn 305, Issue 1, 2013, Pages

Early growth response protein-1 mediates lipotoxicity-associated placental inflammation: Role in maternal obesity

Author keywords

Developmental programming; Early growth response protein 1; Fatty acids; Gestational obesity; Mitogen activated protein kinase

Indexed keywords

CYTOKINE; EARLY GROWTH RESPONSE FACTOR 1; INTERLEUKIN 6; INTERLEUKIN 8; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PALMITIC ACID; PROTEIN C JUN; SATURATED FATTY ACID; TUMOR NECROSIS FACTOR ALPHA;

EID: 84879595431     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00076.2013     Document Type: Article
Times cited : (76)

References (81)
  • 3
    • 33745239304 scopus 로고    scopus 로고
    • Fatty acid-induced inflammation and insulin resistance in skeletal muscle and liver
    • Boden G. Fatty acid-induced inflammation and insulin resistance in skeletal muscle and liver. Curr Diab Rep 6: 177-181, 2006.
    • (2006) Curr Diab Rep , vol.6 , pp. 177-181
    • Boden, G.1
  • 4
    • 84855989961 scopus 로고    scopus 로고
    • Review: The placenta and developmental programming: Balancing fetal nutrient demands with maternal resource allocation
    • Burton GJ, Fowden AL. Review: The placenta and developmental programming: balancing fetal nutrient demands with maternal resource allocation. Placenta 33 Suppl: S23-S27, 2012.
    • (2012) Placenta , vol.33 , Issue.SUPPL.
    • Burton, G.J.1    Fowden, A.L.2
  • 5
    • 34848828244 scopus 로고    scopus 로고
    • Increasing maternal obesity and weight gain during pregnancy: The obstetric problems of plentitude
    • Catalano PM. Increasing maternal obesity and weight gain during pregnancy: the obstetric problems of plentitude. Obstet Gynecol 110: 743-744, 2007.
    • (2007) Obstet Gynecol , vol.110 , pp. 743-744
    • Catalano, P.M.1
  • 8
    • 29244468868 scopus 로고    scopus 로고
    • Placental function in development and disease
    • Cross JC. Placental function in development and disease. Reprod Fertil Dev 18: 71-76, 2006.
    • (2006) Reprod Fertil Dev , vol.18 , pp. 71-76
    • Cross, J.C.1
  • 9
    • 84859404868 scopus 로고    scopus 로고
    • Role of obesity and lipotoxicity in the development of nonalcoholic steatohepatitis: Pathophysiology and clinical implications
    • Cusi K. Role of obesity and lipotoxicity in the development of nonalcoholic steatohepatitis: pathophysiology and clinical implications. Gastroenterology 142: 711-725. e6, 2012.
    • (2012) Gastroenterology , vol.142
    • Cusi, K.1
  • 10
    • 0348222671 scopus 로고    scopus 로고
    • Inflammation: The link between insulin resistance, obesity and diabetes
    • Dandona P, Aljada A, Bandyopadhyay A. Inflammation: the link between insulin resistance, obesity and diabetes. Trends Immunol 25: 4-7, 2004.
    • (2004) Trends Immunol , vol.25 , pp. 4-7
    • Dandona, P.1    Aljada, A.2    Bandyopadhyay, A.3
  • 12
    • 73549124293 scopus 로고    scopus 로고
    • Early growth response 1 (EGR1): A gene with as many names as biological functions
    • DeLigio JT, Zorio DA. Early growth response 1 (EGR1): a gene with as many names as biological functions. Cancer Biol Ther 8: 1889-1892, 2009.
    • (2009) Cancer Biol Ther , vol.8 , pp. 1889-1892
    • DeLigio, J.T.1    Zorio, D.A.2
  • 13
    • 79955046971 scopus 로고    scopus 로고
    • Adiponectin induces interleukin-6 production and its underlying mechanism in adult rat cardiac fibroblasts
    • Fan D, Li L, Wang C, Cui XB, Zhou Y, Wu LL. Adiponectin induces interleukin-6 production and its underlying mechanism in adult rat cardiac fibroblasts. J Cell Physiol 226: 1793-1802, 2011.
    • (2011) J Cell Physiol , vol.226 , pp. 1793-1802
    • Fan, D.1    Li, L.2    Wang, C.3    Cui, X.B.4    Zhou, Y.5    Wu, L.L.6
  • 15
    • 77955981879 scopus 로고    scopus 로고
    • Placental amino acid transport and placental leptin resistance in pregnancies complicated by maternal obesity
    • Farley DM, Choi J, Dudley DJ, Li C, Jenkins SL, Myatt L, Nathanielsz PW. Placental amino acid transport and placental leptin resistance in pregnancies complicated by maternal obesity. Placenta 31: 718-724, 2010.
    • (2010) Placenta , vol.31 , pp. 718-724
    • Farley, D.M.1    Choi, J.2    Dudley, D.J.3    Li, C.4    Jenkins, S.L.5    Myatt, L.6    Nathanielsz, P.W.7
  • 16
    • 84863098121 scopus 로고    scopus 로고
    • Inflammation and fibrogenesis in steatohepatitis
    • Fujii H, Kawada N. Inflammation and fibrogenesis in steatohepatitis. J Gastroenterol 47: 215-225, 2012.
    • (2012) J Gastroenterol , vol.47 , pp. 215-225
    • Fujii, H.1    Kawada, N.2
  • 18
    • 84866271175 scopus 로고    scopus 로고
    • Mechanisms of gene regulation by fatty acids
    • Georgiadi A, Kersten S. Mechanisms of gene regulation by fatty acids. Adv Nutr 3: 127-134, 2012.
    • (2012) Adv Nutr , vol.3 , pp. 127-134
    • Georgiadi, A.1    Kersten, S.2
  • 19
    • 78649804147 scopus 로고    scopus 로고
    • Gene-specific repression of proinflammatory cytokines in stimulated human macrophages by nuclear IkappaBalpha
    • Ghosh CC, Ramaswami S, Juvekar A, Vu HY, Galdieri L, Davidson D, Vancurova I. Gene-specific repression of proinflammatory cytokines in stimulated human macrophages by nuclear IkappaBalpha. J Immunol 185: 3685-3693, 2010.
    • (2010) J Immunol , vol.185 , pp. 3685-3693
    • Ghosh, C.C.1    Ramaswami, S.2    Juvekar, A.3    Vu, H.Y.4    Galdieri, L.5    Davidson, D.6    Vancurova, I.7
  • 21
    • 77949661217 scopus 로고    scopus 로고
    • An NF-kappaB-dependent role for JunB in the induction of proinflammatory cytokines in LPS-activated bone marrow-derived dendritic cells
    • Gomard T, Michaud HA, Tempe D, Thiolon K, Pelegrin M, Piechaczyk M. An NF-kappaB-dependent role for JunB in the induction of proinflammatory cytokines in LPS-activated bone marrow-derived dendritic cells. PLoS One 5: e9585, 2010.
    • (2010) PLoS One , vol.5
    • Gomard, T.1    Michaud, H.A.2    Tempe, D.3    Thiolon, K.4    Pelegrin, M.5    Piechaczyk, M.6
  • 23
    • 58549105701 scopus 로고    scopus 로고
    • Induction of proinflammatory cytokines by long-chain saturated fatty acids in human macrophages
    • Haversen L, Danielsson KN, Fogelstrand L, Wiklund O. Induction of proinflammatory cytokines by long-chain saturated fatty acids in human macrophages. Atherosclerosis 202: 382-393, 2009.
    • (2009) Atherosclerosis , vol.202 , pp. 382-393
    • Haversen, L.1    Danielsson, K.N.2    Fogelstrand, L.3    Wiklund, O.4
  • 25
    • 80052609097 scopus 로고    scopus 로고
    • Prenatal programming of the innate immune response following in utero exposure to inflammation: A sexually dimorphic process?
    • Hodyl NA, Stark MJ, Osei-Kumah A, Clifton VL. Prenatal programming of the innate immune response following in utero exposure to inflammation: a sexually dimorphic process? Expert Rev Clin Immunol 7: 579-592, 2011.
    • (2011) Expert Rev Clin Immunol , vol.7 , pp. 579-592
    • Hodyl, N.A.1    Stark, M.J.2    Osei-Kumah, A.3    Clifton, V.L.4
  • 27
    • 0032825684 scopus 로고    scopus 로고
    • Receptor-mediated signaling pathways: Potential targets of modulation by dietary fatty acids
    • Hwang D, Rhee SH. Receptor-mediated signaling pathways: potential targets of modulation by dietary fatty acids. Am J Clin Nutr 70: 545-556, 1999.
    • (1999) Am J Clin Nutr , vol.70 , pp. 545-556
    • Hwang, D.1    Rhee, S.H.2
  • 29
  • 30
    • 29144511607 scopus 로고    scopus 로고
    • MAPK signalling pathways as molecular targets for antiinflammatory therapy-from molecular mechanisms to therapeutic benefits
    • Kaminska B. MAPK signalling pathways as molecular targets for antiinflammatory therapy-from molecular mechanisms to therapeutic benefits. Biochim Biophys Acta 1754: 253-262, 2005.
    • (2005) Biochim Biophys Acta , vol.1754 , pp. 253-262
    • Kaminska, B.1
  • 31
    • 0033996762 scopus 로고    scopus 로고
    • The I kappa B kinase (IKK) and NF-kappa B: Key elements of proinflammatory signalling
    • Karin M, Delhase M. The I kappa B kinase (IKK) and NF-kappa B: key elements of proinflammatory signalling. Semin Immunol 12: 85-98, 2000.
    • (2000) Semin Immunol , vol.12 , pp. 85-98
    • Karin, M.1    Delhase, M.2
  • 32
    • 0345688686 scopus 로고    scopus 로고
    • Insulin-regulated expression of Egr-1 and Krox20: Dependence on ERK1/2 and interaction with p38 and PI3-kinase pathways
    • Keeton AB, Bortoff KD, Bennett WL, Franklin JL, Venable DY, Messina JL. Insulin-regulated expression of Egr-1 and Krox20: dependence on ERK1/2 and interaction with p38 and PI3-kinase pathways. Endocrinology 144: 5402-5410, 2003.
    • (2003) Endocrinology , vol.144 , pp. 5402-5410
    • Keeton, A.B.1    Bortoff, K.D.2    Bennett, W.L.3    Franklin, J.L.4    Venable, D.Y.5    Messina, J.L.6
  • 34
    • 33750133607 scopus 로고    scopus 로고
    • Maternal obesity, metabolism, and pregnancy outcomes
    • King JC. Maternal obesity, metabolism, and pregnancy outcomes. Annu Rev Nutr 26: 271-291, 2006.
    • (2006) Annu Rev Nutr , vol.26 , pp. 271-291
    • King, J.C.1
  • 36
    • 82355164835 scopus 로고    scopus 로고
    • Increased maternal fat consumption during pregnancy alters body composition in neonatal mice
    • Krasnow SM, Nguyen ML, Marks DL. Increased maternal fat consumption during pregnancy alters body composition in neonatal mice. Am J Physiol Endocrinol Metab 301: E1243-E1253, 2011.
    • (2011) Am J Physiol Endocrinol Metab , vol.301
    • Krasnow, S.M.1    Nguyen, M.L.2    Marks, D.L.3
  • 37
    • 84860165740 scopus 로고    scopus 로고
    • Mammalian MAPK signal transduction pathways activated by stress and inflammation: A 10-year update
    • Kyriakis JM, Avruch J. Mammalian MAPK signal transduction pathways activated by stress and inflammation: a 10-year update. Physiol Rev 92: 689-737, 2012.
    • (2012) Physiol Rev , vol.92 , pp. 689-737
    • Kyriakis, J.M.1    Avruch, J.2
  • 38
    • 0035066383 scopus 로고    scopus 로고
    • Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation
    • Kyriakis JM, Avruch J. Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiol Rev 81: 807-869, 2001.
    • (2001) Physiol Rev , vol.81 , pp. 807-869
    • Kyriakis, J.M.1    Avruch, J.2
  • 39
    • 84874059710 scopus 로고    scopus 로고
    • Oleic acid stimulates system A amino acid transport in primary human trophoblast cells mediated by toll-like receptor 4
    • Lager S, Gaccioli F, Ramirez VI, Jones HN, Jansson T, Powell TL. Oleic acid stimulates system A amino acid transport in primary human trophoblast cells mediated by toll-like receptor 4. J Lipid Res 54: 725-733, 2013.
    • (2013) J Lipid Res , vol.54 , pp. 725-733
    • Lager, S.1    Gaccioli, F.2    Ramirez, V.I.3    Jones, H.N.4    Jansson, T.5    Powell, T.L.6
  • 40
    • 79951512280 scopus 로고    scopus 로고
    • Effect of IL-6 and TNF-alpha on fatty acid uptake in cultured human primary trophoblast cells
    • Lager S, Jansson N, Olsson AL, Wennergren M, Jansson T, Powell TL. Effect of IL-6 and TNF-alpha on fatty acid uptake in cultured human primary trophoblast cells. Placenta 32: 121-127, 2011.
    • (2011) Placenta , vol.32 , pp. 121-127
    • Lager, S.1    Jansson, N.2    Olsson, A.L.3    Wennergren, M.4    Jansson, T.5    Powell, T.L.6
  • 41
    • 14044257221 scopus 로고    scopus 로고
    • The evolving role of inflammation in obesity and the metabolic syndrome
    • Lee YH, Pratley RE. The evolving role of inflammation in obesity and the metabolic syndrome. Curr Diab Rep 5: 70-75, 2005.
    • (2005) Curr Diab Rep , vol.5 , pp. 70-75
    • Lee, Y.H.1    Pratley, R.E.2
  • 42
    • 71749111154 scopus 로고    scopus 로고
    • Targeted knockdown of EGR-1 inhibits IL-8 production and IL-8-mediated invasion of prostate cancer cells through suppressing EGR-1/NF-kappaB synergy
    • Ma J, Ren Z, Ma Y, Xu L, Zhao Y, Zheng C, Fang Y, Xue T, Sun B, Xiao W. Targeted knockdown of EGR-1 inhibits IL-8 production and IL-8-mediated invasion of prostate cancer cells through suppressing EGR-1/NF-kappaB synergy. J Biol Chem 284: 34600-34606, 2009.
    • (2009) J Biol Chem , vol.284 , pp. 34600-34606
    • Ma, J.1    Ren, Z.2    Ma, Y.3    Xu, L.4    Zhao, Y.5    Zheng, C.6    Fang, Y.7    Xue, T.8    Sun, B.9    Xiao, W.10
  • 43
    • 84861313012 scopus 로고    scopus 로고
    • Effects of a high-fat diet exposure in utero on the metabolic syndrome-like phenomenon in mouse offspring through epigenetic changes in adipocytokine gene expression
    • Masuyama H, Hiramatsu Y. Effects of a high-fat diet exposure in utero on the metabolic syndrome-like phenomenon in mouse offspring through epigenetic changes in adipocytokine gene expression. Endocrinology 153: 2823-2830, 2012.
    • (2012) Endocrinology , vol.153 , pp. 2823-2830
    • Masuyama, H.1    Hiramatsu, Y.2
  • 44
    • 0030831210 scopus 로고    scopus 로고
    • A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
    • Medzhitov R, Preston-Hurlburt P, Janeway CA Jr. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 388: 394-397, 1997.
    • (1997) Nature , vol.388 , pp. 394-397
    • Medzhitov, R.1    Preston-Hurlburt, P.2    Janeway Jr., C.A.3
  • 45
    • 35748954371 scopus 로고    scopus 로고
    • Inflammation and endothelial activation is evident at birth in offspring of mothers with type 1 diabetes
    • Nelson SM, Sattar N, Freeman DJ, Walker JD, Lindsay RS. Inflammation and endothelial activation is evident at birth in offspring of mothers with type 1 diabetes. Diabetes 56: 2697-2704, 2007.
    • (2007) Diabetes , vol.56 , pp. 2697-2704
    • Nelson, S.M.1    Sattar, N.2    Freeman, D.J.3    Walker, J.D.4    Lindsay, R.S.5
  • 46
    • 80052868490 scopus 로고    scopus 로고
    • Early growth response 1-a transcription factor in the crossfire of signal transduction cascades
    • Pagel JI, Deindl E. Early growth response 1-a transcription factor in the crossfire of signal transduction cascades. Indian J Biochem Biophys 48: 226-235, 2011.
    • (2011) Indian J Biochem Biophys , vol.48 , pp. 226-235
    • Pagel, J.I.1    Deindl, E.2
  • 48
    • 76349105718 scopus 로고    scopus 로고
    • Lipotoxicity in macrophages: Evidence from diseases associated with the metabolic syndrome
    • Prieur X, Roszer T, Ricote M. Lipotoxicity in macrophages: evidence from diseases associated with the metabolic syndrome. Biochim Biophys Acta 1801: 327-337, 2010.
    • (2010) Biochim Biophys Acta , vol.1801 , pp. 327-337
    • Prieur, X.1    Roszer, T.2    Ricote, M.3
  • 51
    • 39749088057 scopus 로고    scopus 로고
    • Obesity, diabetes, and links to congenital defects: A review of the evidence and recommendations for intervention
    • Reece EA. Obesity, diabetes, and links to congenital defects: a review of the evidence and recommendations for intervention. J Matern Fetal Neonatal Med 21: 173-180, 2008.
    • (2008) J Matern Fetal Neonatal Med , vol.21 , pp. 173-180
    • Reece, E.A.1
  • 52
    • 37349018284 scopus 로고    scopus 로고
    • Perspectives on obesity, pregnancy and birth outcomes in the United States: The scope of the problem
    • Reece EA. Perspectives on obesity, pregnancy and birth outcomes in the United States: the scope of the problem. Am J Obstet Gynecol 198: 23-27, 2008.
    • (2008) Am J Obstet Gynecol , vol.198 , pp. 23-27
    • Reece, E.A.1
  • 53
    • 80052396423 scopus 로고    scopus 로고
    • The biological basis of injury and neuroprotection in the fetal and neonatal brain
    • Rees S, Harding R, Walker D. The biological basis of injury and neuroprotection in the fetal and neonatal brain. Int J Dev Neurosci 29: 551-563, 2011.
    • (2011) Int J Dev Neurosci , vol.29 , pp. 551-563
    • Rees, S.1    Harding, R.2    Walker, D.3
  • 55
    • 14644406272 scopus 로고    scopus 로고
    • Active chromatin domains are defined by acetylation islands revealed by genome-wide mapping
    • Roh TY, Cuddapah S, Zhao K. Active chromatin domains are defined by acetylation islands revealed by genome-wide mapping. Genes Dev 19: 542-552, 2005.
    • (2005) Genes Dev , vol.19 , pp. 542-552
    • Roh, T.Y.1    Cuddapah, S.2    Zhao, K.3
  • 56
    • 77953518974 scopus 로고    scopus 로고
    • Maternal obesity: The interplay between inflammation, mother and fetus
    • Schmatz M, Madan J, Marino T, Davis J. Maternal obesity: the interplay between inflammation, mother and fetus. J Perinatol 30: 441-446, 2010.
    • (2010) J Perinatol , vol.30 , pp. 441-446
    • Schmatz, M.1    Madan, J.2    Marino, T.3    Davis, J.4
  • 57
    • 67649834440 scopus 로고    scopus 로고
    • ChIP-seq: Using high-throughput sequencing to discover protein-DNA interactions
    • Schmidt D, Wilson MD, Spyrou C, Brown GD, Hadfield J, Odom DT. ChIP-seq: using high-throughput sequencing to discover protein-DNA interactions. Methods 48: 240-248, 2009.
    • (2009) Methods , vol.48 , pp. 240-248
    • Schmidt, D.1    Wilson, M.D.2    Spyrou, C.3    Brown, G.D.4    Hadfield, J.5    Odom, D.T.6
  • 63
    • 79954595062 scopus 로고    scopus 로고
    • An early response transcription factor, Egr-1, enhances insulin resistance in type 2 diabetes with chronic hyperinsulinism
    • Shen N, Yu X, Pan FY, Gao X, Xue B, Li CJ. An early response transcription factor, Egr-1, enhances insulin resistance in type 2 diabetes with chronic hyperinsulinism. J Biol Chem 286: 14508-14515, 2011.
    • (2011) J Biol Chem , vol.286 , pp. 14508-14515
    • Shen, N.1    Yu, X.2    Pan, F.Y.3    Gao, X.4    Xue, B.5    Li, C.J.6
  • 64
    • 49449117144 scopus 로고    scopus 로고
    • Regulatory mechanism of TNFalpha autoregulation in HaCaT cells: The role of the transcription factor EGR-1
    • Son SW, Min BW, Lim Y, Lee YH, Shin SY. Regulatory mechanism of TNFalpha autoregulation in HaCaT cells: the role of the transcription factor EGR-1. Biochem Biophys Res Commun 374: 777-782, 2008.
    • (2008) Biochem Biophys Res Commun , vol.374 , pp. 777-782
    • Son, S.W.1    Min, B.W.2    Lim, Y.3    Lee, Y.H.4    Shin, S.Y.5
  • 65
    • 79957851295 scopus 로고    scopus 로고
    • Gestational high fat diet programs hepatic phosphoenolpyruvate carboxykinase gene expression and histone modification in neonatal offspring rats
    • Strakovsky RS, Zhang X, Zhou D, Pan YX. Gestational high fat diet programs hepatic phosphoenolpyruvate carboxykinase gene expression and histone modification in neonatal offspring rats. J Physiol 589: 2707-2717, 2011.
    • (2011) J Physiol , vol.589 , pp. 2707-2717
    • Strakovsky, R.S.1    Zhang, X.2    Zhou, D.3    Pan, Y.X.4
  • 66
    • 79952441661 scopus 로고    scopus 로고
    • Fatty acid-gene interactions, adipokines and obesity
    • Stryjecki C, Mutch DM. Fatty acid-gene interactions, adipokines and obesity. Eur J Clin Nutr 65: 285-297, 2011.
    • (2011) Eur J Clin Nutr , vol.65 , pp. 285-297
    • Stryjecki, C.1    Mutch, D.M.2
  • 67
    • 65349155113 scopus 로고    scopus 로고
    • Early soy exposure via maternal diet regulates rat mammary epithelial differentiation by paracrine signaling from stromal adipocytes
    • Su Y, Shankar K, Simmen RC. Early soy exposure via maternal diet regulates rat mammary epithelial differentiation by paracrine signaling from stromal adipocytes. J Nutr 139: 945-951, 2009.
    • (2009) J Nutr , vol.139 , pp. 945-951
    • Su, Y.1    Shankar, K.2    Simmen, R.C.3
  • 69
    • 26244448904 scopus 로고    scopus 로고
    • A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: Role of free fatty acids and tumor necrosis factor alpha
    • Suganami T, Nishida J, Ogawa Y. A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: role of free fatty acids and tumor necrosis factor alpha. Arterioscler Thromb Vasc Biol 25: 2062-2068, 2005.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 2062-2068
    • Suganami, T.1    Nishida, J.2    Ogawa, Y.3
  • 71
    • 77953724327 scopus 로고    scopus 로고
    • Perinatal environment and its influences on metabolic programming of offspring
    • Tamashiro KL, Moran TH. Perinatal environment and its influences on metabolic programming of offspring. Physiol Behav 100: 560-566, 2010.
    • (2010) Physiol Behav , vol.100 , pp. 560-566
    • Tamashiro, K.L.1    Moran, T.H.2
  • 72
    • 76749133079 scopus 로고    scopus 로고
    • Review: The is a programming agent for cardiovascular disease
    • Thornburg KL, O'Tierney PF, Louey S. Review: The placenta is a programming agent for cardiovascular disease. Placenta 31 Suppl: S54-S59, 2010.
    • (2010) Placenta , vol.31 , Issue.SUPPL.
    • Thornburg, K.L.1    O'Tierney, P.F.2    Louey, S.3
  • 73
  • 75
    • 84875081171 scopus 로고    scopus 로고
    • Mechanisms behind early life nutrition and adult disease outcome
    • Velkoska E, Morris MJ. Mechanisms behind early life nutrition and adult disease outcome. World J Diabetes 2: 127-132, 2011.
    • (2011) World J Diabetes , vol.2 , pp. 127-132
    • Velkoska, E.1    Morris, M.J.2
  • 76
    • 83155193603 scopus 로고    scopus 로고
    • The impact of obesity on oocytes: Evidence for lipotoxicity mechanisms
    • Wu LL, Norman RJ, Robker RL. The impact of obesity on oocytes: evidence for lipotoxicity mechanisms. Reprod Fertil Dev 24: 29-34, 2011.
    • (2011) Reprod Fertil Dev , vol.24 , pp. 29-34
    • Wu, L.L.1    Norman, R.J.2    Robker, R.L.3
  • 77
    • 0030858764 scopus 로고    scopus 로고
    • Lipopolysaccharide induction of the tumor necrosis factor-alpha promoter in human monocytic cells. Regulation by Egr-1, c-Jun, and NF-kappaB transcription factors
    • Yao J, Mackman N, Edgington TS, Fan ST. Lipopolysaccharide induction of the tumor necrosis factor-alpha promoter in human monocytic cells. Regulation by Egr-1, c-Jun, and NF-kappaB transcription factors. J Biol Chem 272: 17795-17801, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 17795-17801
    • Yao, J.1    Mackman, N.2    Edgington, T.S.3    Fan, S.T.4
  • 80
    • 77951974181 scopus 로고    scopus 로고
    • Maternal obesity upregulates inflammatory signaling pathways and enhances cytokine expression in the mid-gestation sheep placenta
    • Zhu MJ, Du M, Nathanielsz PW, Ford SP. Maternal obesity upregulates inflammatory signaling pathways and enhances cytokine expression in the mid-gestation sheep placenta. Placenta 31: 387-391, 2010.
    • (2010) Placenta , vol.31 , pp. 387-391
    • Zhu, M.J.1    Du, M.2    Nathanielsz, P.W.3    Ford, S.P.4
  • 81
    • 78149485096 scopus 로고    scopus 로고
    • Maternal obesity markedly increases placental fatty acid transporter expression and fetal blood triglycerides at midgestation in the ewe
    • Zhu MJ, Ma Y, Long NM, Du M, Ford SP. Maternal obesity markedly increases placental fatty acid transporter expression and fetal blood triglycerides at midgestation in the ewe. Am J Physiol Regul Integr Comp Physiol 299: R1224-R1231, 2010.
    • (2010) Am J Physiol Regul Integr Comp Physiol , vol.299
    • Zhu, M.J.1    Ma, Y.2    Long, N.M.3    Du, M.4    Ford, S.P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.