Fatty acids alter glycerolipid metabolism and induce lipid droplet formation, syncytialisation and cytokine production in human trophoblasts with minimal glucose effect or interaction

Placenta

Volumn 31, Issue 3, 2010, Pages 230-239

  Pathmaperuma, A N ^a   Mana P ^a   Cheung, S N ^a   Kugathas, K ^a   Josiah, A ^a   Koina, M E ^b   Broomfield, A ^b   Delghingaro Augusto, V ^c   Ellwood, D A ^a   Dahlstrom, J E ^a,b   Nolan, C J ^a  

^a The Australian National University   (Australia)

^b CANBERRA HOSPITAL   (Australia)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Cytokine production; Diabetes; Fatty acid esterification; Fatty acid oxidation; Glucose metabolism; Lipid droplet; Lipid metabolism; Lipolysis; Non esterified fatty acids; Obesity; Placenta; Syncytialisation; Trophoblast

Indexed keywords

BOVINE SERUM ALBUMIN; CYTOKINE; FAT DROPLET; FATTY ACID; GLUCOSE; GLYCEROL; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPID; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA;

APOPTOSIS; ARTICLE; CELL CULTURE; CELL PROLIFERATION; CELL VIABILITY; CYTOKINE PRODUCTION; DIABETES MELLITUS; ESTERIFICATION; FATTY ACID OXIDATION; GLUCOSE METABOLISM; HUMAN; HUMAN CELL; LIPID METABOLISM; LIPOLYSIS; OBESITY; PREGNANCY COMPLICATION; PREGNANCY DIABETES MELLITUS; PRIORITY JOURNAL; TROPHOBLAST;

CELL AGGREGATION; CELL SURVIVAL; FEMALE; GLUCOSE; GLYCOLYSIS; HUMANS; LIPID METABOLISM; LIPOLYSIS; MEMBRANE PROTEINS; MICROSCOPY, ELECTRON, SCANNING; PALMITIC ACID; PLACENTA; PREGNANCY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; STATISTICS, NONPARAMETRIC; TROPHOBLASTS;

EID: 76749114889     PISSN: 01434004     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.placenta.2009.12.013     Document Type: Article

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