메뉴 건너뛰기




Volumn 231, Issue 8, 2006, Pages 1379-1397

Physiologic and genomic analyses of nutrition-ethanol interactions during gestation: Implications for fetal ethanol toxicity

Author keywords

Ethanol; Fetal alcohol syndrome; Microarray; Pregnancy; Undernutrition

Indexed keywords

ALCOHOL; ALDEHYDE DEHYDROGENASE; CYTOCHROME P450 2E1; GROWTH HORMONE; MESSENGER RNA; OXIDOREDUCTASE; SOMATOMEDIN C; STAT5A PROTEIN; STAT5B PROTEIN;

EID: 33748316503     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: 10.1177/153537020623100812     Document Type: Article
Times cited : (39)

References (58)
  • 1
    • 0034766778 scopus 로고    scopus 로고
    • Alcohol and pregnancy: Highlights from three decades of research
    • Randall CL. Alcohol and pregnancy: highlights from three decades of research. J Stud Alcohol 62:554-561, 2001.
    • (2001) J Stud Alcohol , vol.62 , pp. 554-561
    • Randall, C.L.1
  • 2
    • 0038175220 scopus 로고    scopus 로고
    • Fetal alcohol syndrome: A growing concern for health care professionals
    • Eustace LW, Kang DH, Coombs D. Fetal alcohol syndrome: a growing concern for health care professionals. J Obstet Gynecol Neonatal Nurs 32:215-221, 2003.
    • (2003) J Obstet Gynecol Neonatal Nurs , vol.32 , pp. 215-221
    • Eustace, L.W.1    Kang, D.H.2    Coombs, D.3
  • 3
    • 0031981536 scopus 로고    scopus 로고
    • Relation of maternal age and pattern of pregnancy drinking to functionally significant cognitive deficit in infancy
    • Jacobson JL, Jacobson SW, Sokol RJ, Ager JW Jr. Relation of maternal age and pattern of pregnancy drinking to functionally significant cognitive deficit in infancy. Alcohol Clin Exp Res 22:345-351, 1998.
    • (1998) Alcohol Clin Exp Res , vol.22 , pp. 345-351
    • Jacobson, J.L.1    Jacobson, S.W.2    Sokol, R.J.3    Ager Jr., J.W.4
  • 4
    • 0027223320 scopus 로고
    • Nutritional factors underlying the expression of the fetal alcohol syndrome
    • Dreosti IE. Nutritional factors underlying the expression of the fetal alcohol syndrome. Ann N Y Acad Sci 678:193-204, 1993.
    • (1993) Ann N Y Acad Sci , vol.678 , pp. 193-204
    • Dreosti, I.E.1
  • 7
    • 0027692455 scopus 로고
    • Evolution of intragastric ethanol infusion model
    • Tsukamoto H, French SW. Evolution of intragastric ethanol infusion model. Alcohol 10:437-441, 1993.
    • (1993) Alcohol , vol.10 , pp. 437-441
    • Tsukamoto, H.1    French, S.W.2
  • 8
    • 0019514567 scopus 로고
    • Interaction of ethanol and nutrition during gestation: Influence on maternal and offspring development in the rat
    • Wiener SG, Shoemaker WJ, Koda LY, Bloom FE. Interaction of ethanol and nutrition during gestation: influence on maternal and offspring development in the rat. J Pharmacol Exp Ther 216:572-579, 1981.
    • (1981) J Pharmacol Exp Ther , vol.216 , pp. 572-579
    • Wiener, S.G.1    Shoemaker, W.J.2    Koda, L.Y.3    Bloom, F.E.4
  • 9
    • 0027370423 scopus 로고
    • Long-term suppression of insulin-like growth factor-1 in rats after in utero ethanol exposure: Relationship to somatic growth
    • Breese CR, D'Costa A, Ingram RL, Lenham J, Sonntag WE. Long-term suppression of insulin-like growth factor-1 in rats after in utero ethanol exposure: relationship to somatic growth. J Pharmacol Exp Ther 264:448-456, 1993.
    • (1993) J Pharmacol Exp Ther , vol.264 , pp. 448-456
    • Breese, C.R.1    D'Costa, A.2    Ingram, R.L.3    Lenham, J.4    Sonntag, W.E.5
  • 11
    • 0027748966 scopus 로고
    • Episodic excretion of ethanol during chronic intragastric ethanol infusion in the male rat: Continuous vs. cyclic ethanol and nutrient infusions
    • Badger TM, Crouch J, Irby D, Hakkak R, Shahare M. Episodic excretion of ethanol during chronic intragastric ethanol infusion in the male rat: continuous vs. cyclic ethanol and nutrient infusions. J Pharmacol Exp Ther 264:938-943, 1993.
    • (1993) J Pharmacol Exp Ther , vol.264 , pp. 938-943
    • Badger, T.M.1    Crouch, J.2    Irby, D.3    Hakkak, R.4    Shahare, M.5
  • 12
    • 0025942953 scopus 로고
    • Effects of short-term ethanol and nutrition on the hepatic microsomal monooxygenase system in a model utilizing total enteral nutrition in the rat
    • Ronis MJ, Lumpkin CK, Ingelman-Sundberg M, Badger TM. Effects of short-term ethanol and nutrition on the hepatic microsomal monooxygenase system in a model utilizing total enteral nutrition in the rat. Alcohol Clin Exp Res 15:693-699, 1991.
    • (1991) Alcohol Clin Exp Res , vol.15 , pp. 693-699
    • Ronis, M.J.1    Lumpkin, C.K.2    Ingelman-Sundberg, M.3    Badger, T.M.4
  • 14
    • 0018815804 scopus 로고
    • Rate-determining factors for ethanol metabolism in vivo during fasting
    • Lumeng L, Bosron WF, Li TK. Rate-determining factors for ethanol metabolism in vivo during fasting. Adv Exp Med Biol 132:489-496, 1980.
    • (1980) Adv Exp Med Biol , vol.132 , pp. 489-496
    • Lumeng, L.1    Bosron, W.F.2    Li, T.K.3
  • 15
    • 0021815153 scopus 로고
    • Carbon tetrachloride-induced lipid peroxidation dependent on an ethanol-inducible form of rabbit liver microsomal cytochrome P-450
    • Johansson I, Ingelman-Sundberg M. Carbon tetrachloride-induced lipid peroxidation dependent on an ethanol-inducible form of rabbit liver microsomal cytochrome P-450. FEBS Lett 183:265-269, 1985.
    • (1985) FEBS Lett , vol.183 , pp. 265-269
    • Johansson, I.1    Ingelman-Sundberg, M.2
  • 16
    • 0037113927 scopus 로고    scopus 로고
    • Ethanol induction of class I alcohol dehydrogenase expression in the rat occurs through alterations in CCAAT/enhancer binding proteins beta and gamma
    • He L, Ronis MJ, Badger TM. Ethanol induction of class I alcohol dehydrogenase expression in the rat occurs through alterations in CCAAT/enhancer binding proteins beta and gamma. J Biol Chem 277:43572-43577, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 43572-43577
    • He, L.1    Ronis, M.J.2    Badger, T.M.3
  • 19
    • 0038021568 scopus 로고    scopus 로고
    • The relationship among circulating insulin-like growth factor (IGF)-I, IGF-binding proteins-1 and -2, and birth anthropometry: A prospective study
    • Boyne MS, Thame M, Bennett FI, Osmond C, Miell JP, Forrester TE. The relationship among circulating insulin-like growth factor (IGF)-I, IGF-binding proteins-1 and -2, and birth anthropometry: a prospective study. J Clin Endocrinol Metab 88:1687-1691, 2003.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 1687-1691
    • Boyne, M.S.1    Thame, M.2    Bennett, F.I.3    Osmond, C.4    Miell, J.P.5    Forrester, T.E.6
  • 20
    • 0036146373 scopus 로고    scopus 로고
    • Newborn birth weight correlates with placental zinc, umbilical insulin-like growth factor I, and leptin levels in preeclampsia
    • Diaz E, Halhali A, Luna C, Diaz L, Avila E, Larrea F. Newborn birth weight correlates with placental zinc, umbilical insulin-like growth factor I, and leptin levels in preeclampsia. Arch Med Res 33:40-47, 2002.
    • (2002) Arch Med Res , vol.33 , pp. 40-47
    • Diaz, E.1    Halhali, A.2    Luna, C.3    Diaz, L.4    Avila, E.5    Larrea, F.6
  • 22
    • 0037590103 scopus 로고    scopus 로고
    • Acute control of insulin-like growth factor-I gene transcription by growth hormone through Stat5b
    • Woelfle J, Billiard J, Rotwein P. Acute control of insulin-like growth factor-I gene transcription by growth hormone through Stat5b. J Biol Chem 278:22696-22702, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 22696-22702
    • Woelfle, J.1    Billiard, J.2    Rotwein, P.3
  • 24
    • 3142653232 scopus 로고    scopus 로고
    • Post-transcriptional regulation of sterol regulatory element-binding protein-1 by ethanol induces class I alcohol dehydrogenase in rat liver
    • He L, Simmen FA, Ronis MJ, Badger TM. Post-transcriptional regulation of sterol regulatory element-binding protein-1 by ethanol induces class I alcohol dehydrogenase in rat liver. J Biol Chem 279:28113-28121, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 28113-28121
    • He, L.1    Simmen, F.A.2    Ronis, M.J.3    Badger, T.M.4
  • 25
    • 0028673605 scopus 로고
    • Role of alcohol dehydrogenase in rat ethanol elimination kinetics
    • Matsumoto H, Fujimiya T, Fukui Y. Role of alcohol dehydrogenase in rat ethanol elimination kinetics. Alcohol Alcohol 29:15-20, 1994.
    • (1994) Alcohol Alcohol , vol.29 , pp. 15-20
    • Matsumoto, H.1    Fujimiya, T.2    Fukui, Y.3
  • 26
    • 0022851547 scopus 로고
    • Hepatic microsomal ethanol-oxidizing system (MEOS): Metabolic aspects and clinical implications
    • Teschke R, Gellert J. Hepatic microsomal ethanol-oxidizing system (MEOS): metabolic aspects and clinical implications. Alcohol Clin Exp Res 10:20S-32S, 1986.
    • (1986) Alcohol Clin Exp Res , vol.10
    • Teschke, R.1    Gellert, J.2
  • 27
    • 0021269628 scopus 로고
    • Effect of fasting on the activity and turnover of rat liver alcohol dehydrogenase
    • Bosron WF, Crabb DW, Housinger TA, Li TK. Effect of fasting on the activity and turnover of rat liver alcohol dehydrogenase. Alcohol Clin Exp Res 8:196-200, 1984.
    • (1984) Alcohol Clin Exp Res , vol.8 , pp. 196-200
    • Bosron, W.F.1    Crabb, D.W.2    Housinger, T.A.3    Li, T.K.4
  • 28
    • 0024594769 scopus 로고
    • Effect of chronic caloric restriction on hepatic enzymes of intermediary metabolism in the male Fischer 344 rat
    • Feuers RJ, Duffy PH, Leakey JA, Turturro A, Mittelstaedt RA, Hart RW. Effect of chronic caloric restriction on hepatic enzymes of intermediary metabolism in the male Fischer 344 rat. Mech Ageing Dev 48:179-189, 1989.
    • (1989) Mech Ageing Dev , vol.48 , pp. 179-189
    • Feuers, R.J.1    Duffy, P.H.2    Leakey, J.A.3    Turturro, A.4    Mittelstaedt, R.A.5    Hart, R.W.6
  • 29
    • 0018749938 scopus 로고
    • Quantitative correlation of ethanol elimination rates in vivo with liver alcohol dehydrogenase activities in fed, fasted and food-restricted rats
    • Lumeng L, Bosron WF, Li TK. Quantitative correlation of ethanol elimination rates in vivo with liver alcohol dehydrogenase activities in fed, fasted and food-restricted rats. Biochem Pharmacol 28:1547-1551, 1979.
    • (1979) Biochem Pharmacol , vol.28 , pp. 1547-1551
    • Lumeng, L.1    Bosron, W.F.2    Li, T.K.3
  • 30
    • 2142650784 scopus 로고    scopus 로고
    • Overview of the role of alcohol dehydrogenase and aldehyde dehydrogenase and their variants in the genesis of alcohol-related pathology
    • Crabb DW, Matsumoto M, Chang D, You M. Overview of the role of alcohol dehydrogenase and aldehyde dehydrogenase and their variants in the genesis of alcohol-related pathology. Proc Nutr Soc 63:49-63, 2004.
    • (2004) Proc Nutr Soc , vol.63 , pp. 49-63
    • Crabb, D.W.1    Matsumoto, M.2    Chang, D.3    You, M.4
  • 31
    • 27244461442 scopus 로고    scopus 로고
    • Effect of STAT5b on rat liver alcohol dehydrogenase
    • Potter JJ, Mezey E. Effect of STAT5b on rat liver alcohol dehydrogenase. Arch Biochem Biophys 391:41-48, 2001.
    • (2001) Arch Biochem Biophys , vol.391 , pp. 41-48
    • Potter, J.J.1    Mezey, E.2
  • 32
    • 0034943544 scopus 로고    scopus 로고
    • The role of C/EBP in nutrient and hormonal regulation of gene expression
    • Roesler WJ. The role of C/EBP in nutrient and hormonal regulation of gene expression. Annu Rev Nutr 21:141-165, 2001.
    • (2001) Annu Rev Nutr , vol.21 , pp. 141-165
    • Roesler, W.J.1
  • 33
    • 0023797153 scopus 로고
    • Insulin-like growth factor I and insulin rapidly increase casein kinase II activity in BALB/c 3T3 fibroblasts
    • Klarlund JK, Czech MP. Insulin-like growth factor I and insulin rapidly increase casein kinase II activity in BALB/c 3T3 fibroblasts. J Biol Chem 263:15872-15875, 1988.
    • (1988) J Biol Chem , vol.263 , pp. 15872-15875
    • Klarlund, J.K.1    Czech, M.P.2
  • 34
    • 0004930979 scopus 로고    scopus 로고
    • The effects of acute administration of ethanol on jejunal protein synthesis and circulating insulin-like growth factor (IGF)-1 and IGF binding proteins in ad libitum fed and nutritionally restricted rats
    • Miell JP, Marway JS, Jones J, Preedy VR. The effects of acute administration of ethanol on jejunal protein synthesis and circulating insulin-like growth factor (IGF)-1 and IGF binding proteins in ad libitum fed and nutritionally restricted rats. Addict Biol 1:371-378, 1996.
    • (1996) Addict Biol , vol.1 , pp. 371-378
    • Miell, J.P.1    Marway, J.S.2    Jones, J.3    Preedy, V.R.4
  • 35
    • 0034928318 scopus 로고    scopus 로고
    • Decreased IGF-I bioavailability after ethanol abuse in alcoholics: Partial restitution after short-term abstinence
    • Rojdmark S, Brismar K. Decreased IGF-I bioavailability after ethanol abuse in alcoholics: partial restitution after short-term abstinence. J Endocrinol Invest 24:476-482, 2001.
    • (2001) J Endocrinol Invest , vol.24 , pp. 476-482
    • Rojdmark, S.1    Brismar, K.2
  • 36
    • 0027376366 scopus 로고
    • Ethanol inhibits the autophosphorylation of the insulin-like growth factor 1 (IGF-1) receptor and IGF-1-mediated proliferation of 3T3 cells
    • Resnicoff M, Sell C, Ambrose D, Baserga R, Rubin R. Ethanol inhibits the autophosphorylation of the insulin-like growth factor 1 (IGF-1) receptor and IGF-1-mediated proliferation of 3T3 cells. J Biol Chem 268:21777-21782, 1993.
    • (1993) J Biol Chem , vol.268 , pp. 21777-21782
    • Resnicoff, M.1    Sell, C.2    Ambrose, D.3    Baserga, R.4    Rubin, R.5
  • 37
    • 0029160488 scopus 로고
    • Effect of ethanol on plasma and hepatic insulin-like growth factor regulation in pregnant rats
    • Breese CR, Sonntag WE. Effect of ethanol on plasma and hepatic insulin-like growth factor regulation in pregnant rats. Alcohol Clin Exp Res 19:867-873, 1995.
    • (1995) Alcohol Clin Exp Res , vol.19 , pp. 867-873
    • Breese, C.R.1    Sonntag, W.E.2
  • 38
    • 0034082772 scopus 로고    scopus 로고
    • Conditional knockout of mouse insulinlike growth factor-1 gene using the Cre/loxP system
    • Liu JL, Yakar S, LeRoith D. Conditional knockout of mouse insulinlike growth factor-1 gene using the Cre/loxP system. Proc Soc Exp Biol Med 223:344-351, 2000.
    • (2000) Proc Soc Exp Biol Med , vol.223 , pp. 344-351
    • Liu, J.L.1    Yakar, S.2    LeRoith, D.3
  • 43
    • 0041419333 scopus 로고    scopus 로고
    • Effects of chronic ethanol on hepatic and renal CYP2C11 in the male rat: Interactions with the Janus-kinase 2-signal transducer and activators of transcription proteins 5b pathway
    • Badger TM, Ronis MJ, Frank SJ, Chen Y, He L. Effects of chronic ethanol on hepatic and renal CYP2C11 in the male rat: interactions with the Janus-kinase 2-signal transducer and activators of transcription proteins 5b pathway. Endocrinology 144:3969-3976, 2003.
    • (2003) Endocrinology , vol.144 , pp. 3969-3976
    • Badger, T.M.1    Ronis, M.J.2    Frank, S.J.3    Chen, Y.4    He, L.5
  • 44
    • 0036860319 scopus 로고    scopus 로고
    • Alcohol suppresses insulin-like growth factor-1 gene expression in prepubertal transgenic female mice overexpressing the bovine growth hormone gene
    • Srivastava VK, Dearth RK, Hiney JK, Chandrashekar V, Mattison JA, Bartke A, Dees WL. Alcohol suppresses insulin-like growth factor-1 gene expression in prepubertal transgenic female mice overexpressing the bovine growth hormone gene. Alcohol Clin Exp Res 26:1697-1702, 2002.
    • (2002) Alcohol Clin Exp Res , vol.26 , pp. 1697-1702
    • Srivastava, V.K.1    Dearth, R.K.2    Hiney, J.K.3    Chandrashekar, V.4    Mattison, J.A.5    Bartke, A.6    Dees, W.L.7
  • 45
    • 0028484053 scopus 로고
    • Insulin-like growth factors (IGF-I and IGF-II), IGF-binding proteins, and IGF gene expression in the offspring of ethanol-fed rats
    • Singh SP, Srivenugopal KS, Ehmann S, Yuan XH, Snyder AK. Insulin-like growth factors (IGF-I and IGF-II), IGF-binding proteins, and IGF gene expression in the offspring of ethanol-fed rats. J Lab Clin Med 124:183-192, 1994.
    • (1994) J Lab Clin Med , vol.124 , pp. 183-192
    • Singh, S.P.1    Srivenugopal, K.S.2    Ehmann, S.3    Yuan, X.H.4    Snyder, A.K.5
  • 46
    • 0027848843 scopus 로고
    • Effect of ethanol exposure on circulating levels of insulin-like growth factor I and II, and insulin-like growth factor binding proteins in fetal rats
    • Mauceri HJ, Unterman T, Dempsey S, Lee WH, Conway S. Effect of ethanol exposure on circulating levels of insulin-like growth factor I and II, and insulin-like growth factor binding proteins in fetal rats. Alcohol Clin Exp Res 17:1201-1206, 1993.
    • (1993) Alcohol Clin Exp Res , vol.17 , pp. 1201-1206
    • Mauceri, H.J.1    Unterman, T.2    Dempsey, S.3    Lee, W.H.4    Conway, S.5
  • 47
    • 0036324652 scopus 로고    scopus 로고
    • Altered placental development and intrauterine growth restriction in IGF binding protein-1 transgenic mice
    • Crossey PA, Pillai CC, Miell JP. Altered placental development and intrauterine growth restriction in IGF binding protein-1 transgenic mice. J Clin Invest 110:411-418, 2002.
    • (2002) J Clin Invest , vol.110 , pp. 411-418
    • Crossey, P.A.1    Pillai, C.C.2    Miell, J.P.3
  • 48
    • 0141838042 scopus 로고    scopus 로고
    • The insulin-like growth factors and feto-placental growth
    • Fowden AL. The insulin-like growth factors and feto-placental growth. Placenta 24:803-812, 2003.
    • (2003) Placenta , vol.24 , pp. 803-812
    • Fowden, A.L.1
  • 49
    • 0028958031 scopus 로고
    • Insulin-like growth factors and their binding proteins: Biological actions
    • Jones JI, Clemmons DR. Insulin-like growth factors and their binding proteins: biological actions. Endocr Rev 16:3-34, 1995.
    • (1995) Endocr Rev , vol.16 , pp. 3-34
    • Jones, J.I.1    Clemmons, D.R.2
  • 50
    • 27844517009 scopus 로고    scopus 로고
    • The effects of alcohol on rat placenta
    • Turan AM, Arzu KE. The effects of alcohol on rat placenta. Cell Biochem Funct 23:435-445, 2005.
    • (2005) Cell Biochem Funct , vol.23 , pp. 435-445
    • Turan, A.M.1    Arzu, K.E.2
  • 51
    • 0028065053 scopus 로고
    • Chronic ethanol exposure inhibits insulin and IGF-1 stimulated amino acid uptake in cultured human placental trophoblasts
    • Karl PI, Fisher SE. Chronic ethanol exposure inhibits insulin and IGF-1 stimulated amino acid uptake in cultured human placental trophoblasts. Alcohol Clin Exp Res 18:942-946, 1994.
    • (1994) Alcohol Clin Exp Res , vol.18 , pp. 942-946
    • Karl, P.I.1    Fisher, S.E.2
  • 52
    • 0036521544 scopus 로고    scopus 로고
    • Metallothionein protection against alcoholic liver injury through inhibition of oxidative stress
    • Zhou Z, Sun X, James Kang Y. Metallothionein protection against alcoholic liver injury through inhibition of oxidative stress. Exp Biol Med 227:214-222, 2002.
    • (2002) Exp Biol Med , vol.227 , pp. 214-222
    • Zhou, Z.1    Sun, X.2    James Kang, Y.3
  • 53
    • 0038323922 scopus 로고    scopus 로고
    • Suppression of Fas-mediated signaling pathway is involved in zinc inhibition of ethanol-induced liver apoptosis
    • Lambert JC, Zhou Z, Kang YJ. Suppression of Fas-mediated signaling pathway is involved in zinc inhibition of ethanol-induced liver apoptosis. Exp Biol Med 228:406-412, 2003.
    • (2003) Exp Biol Med , vol.228 , pp. 406-412
    • Lambert, J.C.1    Zhou, Z.2    Kang, Y.J.3
  • 54
    • 0036083963 scopus 로고    scopus 로고
    • Metallothionein-independent zinc protection from alcoholic liver injury
    • Zhou Z, Sun X, Lambert JC, Saari JT, Kang YJ. Metallothionein-independent zinc protection from alcoholic liver injury. Am J Pathol 160:2267-2274, 2002.
    • (2002) Am J Pathol , vol.160 , pp. 2267-2274
    • Zhou, Z.1    Sun, X.2    Lambert, J.C.3    Saari, J.T.4    Kang, Y.J.5
  • 55
    • 19544364689 scopus 로고    scopus 로고
    • Zinc supplementation prevents alcoholic liver injury in mice through attenuation of oxidative stress
    • Zhou Z, Wang L, Song Z, Saari JT, McClain CJ, Kang YJ. Zinc supplementation prevents alcoholic liver injury in mice through attenuation of oxidative stress. Am J Pathol 166:1681-1690, 2005.
    • (2005) Am J Pathol , vol.166 , pp. 1681-1690
    • Zhou, Z.1    Wang, L.2    Song, Z.3    Saari, J.T.4    McClain, C.J.5    Kang, Y.J.6
  • 56
    • 0034089297 scopus 로고    scopus 로고
    • Maternal ethanol exposure is associated with decreased plasma zinc and increased fetal abnormalities in normal but not metallothionein-null mice
    • Carey LC, Coyle P, Philcox JC, Rofe AM. Maternal ethanol exposure is associated with decreased plasma zinc and increased fetal abnormalities in normal but not metallothionein-null mice. Alcohol Clin Exp Res. 24:213-219, 2000.
    • (2000) Alcohol Clin Exp Res , vol.24 , pp. 213-219
    • Carey, L.C.1    Coyle, P.2    Philcox, J.C.3    Rofe, A.M.4
  • 57
    • 0037254822 scopus 로고    scopus 로고
    • Zinc supplementation at the time of ethanol exposure ameliorates teratogenicity in mice
    • Carey LC, Coyle P, Philcox JC, Rofe AM. Zinc supplementation at the time of ethanol exposure ameliorates teratogenicity in mice. Alcohol Clin Exp Res 27:107-110, 2003.
    • (2003) Alcohol Clin Exp Res , vol.27 , pp. 107-110
    • Carey, L.C.1    Coyle, P.2    Philcox, J.C.3    Rofe, A.M.4
  • 58
    • 33644826313 scopus 로고    scopus 로고
    • Prenatal zinc treatment at the time of acute ethanol exposure limits spatial memory impairments in mouse offspring
    • Summers BL, Rofe AM, Coyle P. Prenatal zinc treatment at the time of acute ethanol exposure limits spatial memory impairments in mouse offspring. Pediatr Res 59:66-71, 2006.
    • (2006) Pediatr Res , vol.59 , pp. 66-71
    • Summers, B.L.1    Rofe, A.M.2    Coyle, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.