Interfacial cavity filling to optimize CD4-mimetic miniprotein interactions with HIV-1 surface glycoprotein

Journal of Medicinal Chemistry

Volumn 56, Issue 12, 2013, Pages 5033-5047

  Morellato Castillo, Laurence ^a   Acharya, Priyamvada ^b   Combes, Olivier ^a   Michiels, Johan ^c   Descours, Anne ^a   Ramos, Oscar H P ^a   Yang, Yongping ^b   Vanham, Guido ^c   Ariën, Kevin K ^c   Kwong, Peter D ^b   Martin, Loïc ^a   Kessler, Pascal ^a  

^a Institute Frederic Joliot   (France)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^c INSTITUTE OF TROPICAL MEDICINE   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOPHENYLALANINE; AMINO ACID; CLUSTER OF DIFFERENTIATION 4 MINIPROTEIN; GLYCOPROTEIN; HUMAN IMMUNODEFICIENCY VIRUS 1 SURFACE GLYCOPROTEIN; M 48U 12; MICROBICIDE; PHENYLALANINE; PHENYLALANINE DERIVATIVE; PROTEIN; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; VIRUS NEUTRALIZATION;

AMINO ACID SEQUENCE; ANTI-HIV AGENTS; ANTIGENS, CD4; BINDING, COMPETITIVE; CELL LINE; HIV ENVELOPE PROTEIN GP120; HIV-1; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; VIRUS INTERNALIZATION;

EID: 84879560079     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm4002988     Document Type: Article

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