Scorpion-toxin mimics of CD4 in complex with human immunodeficiency virus gp120: Crystal structures, molecular mimicry, and neutralization breadth

Structure

Volumn 13, Issue 5, 2005, Pages 755-768

  Huang, Chih Chin ^a   Stricher, François ^b   Martin, Loïc ^b   Decker, Julie M ^c   Majeed, Shahzad ^a   Barthe, Philippe ^d   Hendrickson, Wayne A ^e   Robinson, James ^f   Roumestand, Christian ^d   Sodroski, Joseph ^g,h,i   Wyatt, Richard ^a   Shaw, George M ^c   Vita, Claudio ^b   Kwong, Peter D ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b CEA SACLAY   (France)

^c University of Alabama at Birmingham   (United States)

^d UNIV MONTPELLIER   (France)

^e Och Spine at New York Presbyterian Hospitals   (United States)

^f TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g DANA FARBER CANCER INSTITUTE   (United States)

^h HARVARD MEDICAL SCHOOL   (United States)

ⁱ HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD 4 M 33; CD4 ANTIGEN; LIGAND; PROTEIN; PROTEIN F 23; SCORPION VENOM; UNCLASSIFIED DRUG; VIRUS GLYCOPROTEIN; VIRUS GLYCOPROTEIN 120;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2; MOLECULAR MIMICRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; PROTEIN STABILITY; QUANTITATIVE ANALYSIS; SIMIAN IMMUNODEFICIENCY VIRUS; THERMODYNAMICS; VIRUS ENVELOPE; VIRUS ISOLATION; X RAY CRYSTALLOGRAPHY;

ANIMALS; ANTI-HIV AGENTS; ANTIGENS, CD4; CRYSTALLOGRAPHY, X-RAY; HIV ENVELOPE PROTEIN GP120; HIV-1; HUMANS; LIGANDS; MOLECULAR MIMICRY; PROTEIN CONFORMATION; SCORPION VENOMS; THERMODYNAMICS;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2; SCORPIONES; SIMIAE; SIMIAN IMMUNODEFICIENCY VIRUS;

EID: 21044438453     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.str.2005.03.006     Document Type: Article

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