메뉴 건너뛰기




Volumn 5, Issue 5, 2000, Pages 183-194

HIV-1 entry - An expanding portal for drug discovery

Author keywords

[No Author keywords available]

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; ANTIVIRUS AGENT; NEW DRUG; RANTES;

EID: 0034194615     PISSN: 13596446     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1359-6446(00)01484-7     Document Type: Review
Times cited : (78)

References (66)
  • 1
    • 2642709177 scopus 로고    scopus 로고
    • Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV outpatient study investigators
    • Palella F.J.et al. Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV outpatient study investigators. New Engl. J. Med. 338:1998;853-860.
    • (1998) New Engl. J. Med. , vol.338 , pp. 853-860
    • Palella, F.J.1
  • 2
    • 0032953920 scopus 로고    scopus 로고
    • + T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy
    • + T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy. Nat. Med. 5:1999;512-517.
    • (1999) Nat. Med. , vol.5 , pp. 512-517
    • Finzi, D.1
  • 3
    • 0033615290 scopus 로고    scopus 로고
    • Primary HIV-1 resistance: A new phase in the epidemic?
    • Pomeranntz R.J. Primary HIV-1 resistance: a new phase in the epidemic? J. Am. Med. Assoc. 282:1999;1177-1179.
    • (1999) J. Am. Med. Assoc. , vol.282 , pp. 1177-1179
    • Pomeranntz, R.J.1
  • 4
    • 0010977793 scopus 로고    scopus 로고
    • Latency and reservoirs for HIV-1
    • Siliciano R.F. Latency and reservoirs for HIV-1. AIDS. 13:1999;S49-S58.
    • (1999) AIDS , vol.13 , pp. 49-S58
    • Siliciano, R.F.1
  • 5
    • 0031729823 scopus 로고    scopus 로고
    • Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry
    • Kilby J.M.et al. Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry. Nat. Med. 4:1998;1302-1307.
    • (1998) Nat. Med. , vol.4 , pp. 1302-1307
    • Kilby, J.M.1
  • 6
    • 0032893134 scopus 로고    scopus 로고
    • HIV-1 attachment: Another look
    • Ugolini S.et al. HIV-1 attachment. another look Trends Microbiol. 7:1999;144-149.
    • (1999) Trends Microbiol. , vol.7 , pp. 144-149
    • Ugolini, S.1
  • 7
    • 0032546844 scopus 로고    scopus 로고
    • The HIV-1 envelope glycoproteins: Fusogens, antigens, and immunogens
    • Wyatt R.et al. The HIV-1 envelope glycoproteins. fusogens, antigens, and immunogens Science. 280:1998;1884-1888.
    • (1998) Science , vol.280 , pp. 1884-1888
    • Wyatt, R.1
  • 8
    • 0032577550 scopus 로고    scopus 로고
    • HIV entry and its inhibition
    • Chan D.C.et al. HIV entry and its inhibition. Cell. 93:1998;681-684.
    • (1998) Cell , vol.93 , pp. 681-684
    • Chan, D.C.1
  • 9
    • 0030770546 scopus 로고    scopus 로고
    • Unwelcomed guests with master keys: How HIV uses chemokine receptors for cellular entry
    • Doms R.W.et al. Unwelcomed guests with master keys. how HIV uses chemokine receptors for cellular entry Virology. 235:1997;179-190.
    • (1997) Virology , vol.235 , pp. 179-190
    • Doms, R.W.1
  • 10
    • 0032543307 scopus 로고    scopus 로고
    • Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody
    • Kwong P.D.et al. Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody. Nature. 393:1998;648-659.
    • (1998) Nature , vol.393 , pp. 648-659
    • Kwong, P.D.1
  • 11
    • 0032543555 scopus 로고    scopus 로고
    • The antigenic structure of the HIV gp120 envelope glycoprotein
    • Wyatt R.et al. The antigenic structure of the HIV gp120 envelope glycoprotein. Nature. 393:1998;705-710.
    • (1998) Nature , vol.393 , pp. 705-710
    • Wyatt, R.1
  • 12
    • 0032546952 scopus 로고    scopus 로고
    • A conserved HIV gp120 glycoprotein structure involved in chemokine receptor binding
    • Rizzuto C.D.et al. A conserved HIV gp120 glycoprotein structure involved in chemokine receptor binding. Science. 280:1998;1949-1953.
    • (1998) Science , vol.280 , pp. 1949-1953
    • Rizzuto, C.D.1
  • 13
    • 0025832880 scopus 로고
    • The CD4-gp120 interaction and AIDS pathogenesis
    • Capon D.J.et al. The CD4-gp120 interaction and AIDS pathogenesis. Annu. Rev. Immunol. 9:1991;649-678.
    • (1991) Annu. Rev. Immunol. , vol.9 , pp. 649-678
    • Capon, D.J.1
  • 14
    • 0025794308 scopus 로고
    • Relative resistance of primary HIV-1 isolates to neutralization by soluble CD4
    • Daar E.S.et al. Relative resistance of primary HIV-1 isolates to neutralization by soluble CD4. Am. J. Med. 90(Suppl. 4A):1991;22S-26S.
    • (1991) Am. J. Med. , vol.90 , Issue.SUPPL. 4A
    • Daar, E.S.1
  • 15
    • 0026601827 scopus 로고
    • Virions of primary human immunodeficiency virus type 1 isolates resistant to soluble CD4 (sCD4) neutralization differ in sCD4 binding and glycoprotein gp120 retention from sCD4-sensitive isolates
    • Moore J.P.et al. Virions of primary human immunodeficiency virus type 1 isolates resistant to soluble CD4 (sCD4) neutralization differ in sCD4 binding and glycoprotein gp120 retention from sCD4-sensitive isolates. J. Virol. 66:1992;235-243.
    • (1992) J. Virol. , vol.66 , pp. 235-243
    • Moore, J.P.1
  • 16
    • 0029062687 scopus 로고
    • Expression and characterization of CD4-IgG2, a novel heterotetramer that neutralizes primary HIV type 1 isolates
    • Allaway G.P.et al. Expression and characterization of CD4-IgG2, a novel heterotetramer that neutralizes primary HIV type 1 isolates. AIDS Res. Hum. Retroviruses. 11:1995;533-539.
    • (1995) AIDS Res. Hum. Retroviruses , vol.11 , pp. 533-539
    • Allaway, G.P.1
  • 17
    • 0031900546 scopus 로고    scopus 로고
    • CD4-immunoglobulin G2 protects Hu-PBL-SCID mice against challenge by primary human immunodeficiency virus type 1 isolates
    • Gauduin M.-C.et al. CD4-immunoglobulin G2 protects Hu-PBL-SCID mice against challenge by primary human immunodeficiency virus type 1 isolates. J. Virol. 72:1998;3475-3478.
    • (1998) J. Virol. , vol.72 , pp. 3475-3478
    • Gauduin, M.-C.1
  • 18
    • 0030892224 scopus 로고    scopus 로고
    • FP-21399 blocks HIV envelope protein-mediated membrane fusion and concentrates in lymph nodes
    • Ono M.et al. FP-21399 blocks HIV envelope protein-mediated membrane fusion and concentrates in lymph nodes. Nat. Biotechnol. 15:1997;343-348.
    • (1997) Nat. Biotechnol. , vol.15 , pp. 343-348
    • Ono, M.1
  • 19
    • 17544388251 scopus 로고    scopus 로고
    • The bis-azo compound FP-21399 inhibits HIV-1 replication by preventing viral entry
    • Zhang J.L.et al. The bis-azo compound FP-21399 inhibits HIV-1 replication by preventing viral entry. Virology. 244:1998;530-541.
    • (1998) Virology , vol.244 , pp. 530-541
    • Zhang, J.L.1
  • 20
    • 0028824505 scopus 로고
    • T30177, an oligonucleotide stabilized by an intramolecular guanosine octet, is a potent inhibitor of laboratory strains and clinical isolates of human immunodeficiency virus type 1
    • Ojwang J.O.et al. T30177, an oligonucleotide stabilized by an intramolecular guanosine octet, is a potent inhibitor of laboratory strains and clinical isolates of human immunodeficiency virus type 1. Antimicrob. Agents Chemother. 39:1995;2426-2435.
    • (1995) Antimicrob. Agents Chemother. , vol.39 , pp. 2426-2435
    • Ojwang, J.O.1
  • 21
    • 0031886388 scopus 로고    scopus 로고
    • Human immunodeficiency virus glycoprotein gp120 as the primary target for the antiviral action of AR177 (Zintevir)
    • Este J.A.et al. Human immunodeficiency virus glycoprotein gp120 as the primary target for the antiviral action of AR177 (Zintevir). Mol. Pharmacol. 53:1998;340-345.
    • (1998) Mol. Pharmacol. , vol.53 , pp. 340-345
    • Este, J.A.1
  • 22
    • 0030302474 scopus 로고    scopus 로고
    • Repeat-dose toxicity and pharmacokinetics of a partial phosphorothioate anti-HIV oligonucleotide (AR177) after bolus intravenous administration to cynomolgus monkeys
    • Wallace T.L.et al. Repeat-dose toxicity and pharmacokinetics of a partial phosphorothioate anti-HIV oligonucleotide (AR177) after bolus intravenous administration to cynomolgus monkeys. J. Pharmacol. Exp. Ther. 278:1996;1313-1317.
    • (1996) J. Pharmacol. Exp. Ther. , vol.278 , pp. 1313-1317
    • Wallace, T.L.1
  • 23
    • 13344262687 scopus 로고    scopus 로고
    • Naphthalene sulfonate polymers with CD4-blocking and anti-human immunodeficiency virus type 1 activities
    • Rusconi S.et al. Naphthalene sulfonate polymers with CD4-blocking and anti-human immunodeficiency virus type 1 activities. Antimicrob. Agents Chemother. 40:1996;234-236.
    • (1996) Antimicrob. Agents Chemother. , vol.40 , pp. 234-236
    • Rusconi, S.1
  • 24
    • 0033047793 scopus 로고    scopus 로고
    • The topical microbicide PRO 2000 protects against genital herpes infection in a mouse model
    • Bourne N.et al. The topical microbicide PRO 2000 protects against genital herpes infection in a mouse model. J. Infect. Dis. 180:1999;203-205.
    • (1999) J. Infect. Dis. , vol.180 , pp. 203-205
    • Bourne, N.1
  • 25
    • 0542398021 scopus 로고    scopus 로고
    • Recent developments in the chemotherapy of HIV infections
    • DeClercq E. Recent developments in the chemotherapy of HIV infections. Pure Appl. Chem. 70:1998;567-577.
    • (1998) Pure Appl. Chem. , vol.70 , pp. 567-577
    • Declercq, E.1
  • 26
    • 0032485443 scopus 로고    scopus 로고
    • Reduction of the viral load of HIV-1 after the intraperitoneal administration of dextrin 2-sulphate in patients with AIDS
    • Shaunak S.et al. Reduction of the viral load of HIV-1 after the intraperitoneal administration of dextrin 2-sulphate in patients with AIDS. AIDS. 12:1998;399-409.
    • (1998) AIDS , vol.12 , pp. 399-409
    • Shaunak, S.1
  • 27
    • 0029065699 scopus 로고
    • - cells by two distinct mechanisms
    • - cells by two distinct mechanisms. Proc. Natl. Acad. Sci. U. S. A. 92:1995;4867-4871.
    • (1995) Proc. Natl. Acad. Sci. U. S. A. , vol.92 , pp. 4867-4871
    • Yahi, N.1
  • 28
    • 0031924987 scopus 로고    scopus 로고
    • Effect on normal vaginal flora of three intravaginal microbicidal agents potentially active against human immunodeficiency virus type 1
    • Rosenstein I.J.et al. Effect on normal vaginal flora of three intravaginal microbicidal agents potentially active against human immunodeficiency virus type 1. J. Infect. Dis. 177:1998;1386-1390.
    • (1998) J. Infect. Dis. , vol.177 , pp. 1386-1390
    • Rosenstein, I.J.1
  • 29
    • 0032605777 scopus 로고    scopus 로고
    • Role of chemokine receptors in HIV-1 infection and pathogenesis
    • Ross T.et al. Role of chemokine receptors in HIV-1 infection and pathogenesis. Adv. Virus Res. 52:1999;233-267.
    • (1999) Adv. Virus Res. , vol.52 , pp. 233-267
    • Ross, T.1
  • 30
    • 0029805881 scopus 로고    scopus 로고
    • Evidence for cell-surface association between fusin and the CD4-gp120 complex in human cell lines
    • Lapham C.K.et al. Evidence for cell-surface association between fusin and the CD4-gp120 complex in human cell lines. Science. 274:1996;602-605.
    • (1996) Science , vol.274 , pp. 602-605
    • Lapham, C.K.1
  • 31
    • 16144365317 scopus 로고    scopus 로고
    • CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5
    • Trkola A.et al. CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5. Nature. 384:1996;184-187.
    • (1996) Nature , vol.384 , pp. 184-187
    • Trkola, A.1
  • 32
    • 16144365650 scopus 로고    scopus 로고
    • CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5
    • Wu L.et al. CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5. Nature. 384:1996;179-183.
    • (1996) Nature , vol.384 , pp. 179-183
    • Wu, L.1
  • 33
    • 0026656502 scopus 로고
    • Human immunodeficiency virus type 2 infection and fusion of CD4-negative human cell lines: Induction and enhancement by soluble CD4
    • Clapham P.R.et al. Human immunodeficiency virus type 2 infection and fusion of CD4-negative human cell lines. induction and enhancement by soluble CD4 J. Virol. 66:1992;3531-3537.
    • (1992) J. Virol. , vol.66 , pp. 3531-3537
    • Clapham, P.R.1
  • 34
    • 0025783669 scopus 로고
    • Identification of the envelope V3 loop as the primary determinant of cell tropism in HIV-1
    • Hwang S.S.et al. Identification of the envelope V3 loop as the primary determinant of cell tropism in HIV-1. Science. 253:1991;71-74.
    • (1991) Science , vol.253 , pp. 71-74
    • Hwang, S.S.1
  • 35
    • 0026089184 scopus 로고
    • Macrophage and T cell-line tropisms of HIV-1 are determined by specific regions of the envelope gp120 gene
    • Shioda T.et al. Macrophage and T cell-line tropisms of HIV-1 are determined by specific regions of the envelope gp120 gene. Nature. 349:1991;167-169.
    • (1991) Nature , vol.349 , pp. 167-169
    • Shioda, T.1
  • 36
    • 0032990223 scopus 로고    scopus 로고
    • Stable exposure of the coreceptor-binding site in a CD4-independent HIV-1 envelope protein
    • Hoffman T.L.et al. Stable exposure of the coreceptor-binding site in a CD4-independent HIV-1 envelope protein. Proc. Natl. Acad. Sci. U. S. A. 96:1999;6359-6364.
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.96 , pp. 6359-6364
    • Hoffman, T.L.1
  • 37
    • 0031575431 scopus 로고    scopus 로고
    • Change in coreceptor use correlates with disease progression in HIV-1-infected individuals
    • Connor R.I.et al. Change in coreceptor use correlates with disease progression in HIV-1-infected individuals. J. Exp. Med. 185:1997;621-628.
    • (1997) J. Exp. Med. , vol.185 , pp. 621-628
    • Connor, R.I.1
  • 38
    • 15844388931 scopus 로고    scopus 로고
    • Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection
    • Liu R.et al. Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection. Cell. 86:1996;367-377.
    • (1996) Cell , vol.86 , pp. 367-377
    • Liu, R.1
  • 39
    • 0033008471 scopus 로고    scopus 로고
    • Will multiple coreceptors need to be targeted by inhibitors of human immunodeficiency virus type I entry?
    • Zhang Y-J.et al. Will multiple coreceptors need to be targeted by inhibitors of human immunodeficiency virus type I entry? J. Virol. 73:1999;3443-3448.
    • (1999) J. Virol. , vol.73 , pp. 3443-3448
    • Zhang, Y.-J.1
  • 40
    • 0032924183 scopus 로고    scopus 로고
    • Highly potent RANTES analogues either prevent CCR5-using human immunodeficiency virus type 1 infection in vivo or rapidly select for CXCR4-using variants
    • Mosier D.E.et al. Highly potent RANTES analogues either prevent CCR5-using human immunodeficiency virus type 1 infection in vivo or rapidly select for CXCR4-using variants. J. Virol. 73:1999;3544-3550.
    • (1999) J. Virol. , vol.73 , pp. 3544-3550
    • Mosier, D.E.1
  • 41
    • 0032507962 scopus 로고    scopus 로고
    • Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development
    • Zou Y.-R.et al. Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development. Nature. 393:1998;595-599.
    • (1998) Nature , vol.393 , pp. 595-599
    • Zou, Y.-R.1
  • 42
    • 0029758113 scopus 로고    scopus 로고
    • Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1
    • Nagasawa T.et al. Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1. Nature. 382:1996;635-638.
    • (1996) Nature , vol.382 , pp. 635-638
    • Nagasawa, T.1
  • 43
    • 13144262826 scopus 로고    scopus 로고
    • + T cells: Role of signal transduction
    • + T cells. role of signal transduction Proc. Natl. Acad. Sci. U. S. A. 95:1998;11880-11885.
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , pp. 11880-11885
    • Kinter, A.1
  • 44
    • 0031809008 scopus 로고    scopus 로고
    • Chemokines and HIV-1 second receptors: The therapeutic connection
    • Cairns J.S.et al. Chemokines and HIV-1 second receptors. the therapeutic connection Nat. Med. 4:1998;563-568.
    • (1998) Nat. Med. , vol.4 , pp. 563-568
    • Cairns, J.S.1
  • 45
    • 0027094178 scopus 로고
    • A novel anti-HIV synthetic peptide, T-22 ([Tyr5,12,Lys7]-polyphemusin II)
    • Tamamura H.et al. A novel anti-HIV synthetic peptide, T-22 ([Tyr5,12,Lys7]-polyphemusin II). Biochem. Biophys. Res. Commun. 189:1992;845-850.
    • (1992) Biochem. Biophys. Res. Commun. , vol.189 , pp. 845-850
    • Tamamura, H.1
  • 46
    • 0032954383 scopus 로고    scopus 로고
    • T134, a small-molecule CXCR4 inhibitor, has no cross-drug resistance with AMD3100, a CXCR4 antagonist with a different structure
    • Arakaki R.et al. T134, a small-molecule CXCR4 inhibitor, has no cross-drug resistance with AMD3100, a CXCR4 antagonist with a different structure. J. Virol. 73:1999;1719-1723.
    • (1999) J. Virol. , vol.73 , pp. 1719-1723
    • Arakaki, R.1
  • 47
    • 0030780377 scopus 로고    scopus 로고
    • A small molecule CXCR4 inhibitor that blocks T cell line-tropic HIV-1 infection
    • Murakami T.et al. A small molecule CXCR4 inhibitor that blocks T cell line-tropic HIV-1 infection. J. Exp. Med. 186:1997;1389-1393.
    • (1997) J. Exp. Med. , vol.186 , pp. 1389-1393
    • Murakami, T.1
  • 48
    • 0030773515 scopus 로고    scopus 로고
    • A small-molecule inhibitor directed against the chemokine receptor CXCR4 prevents its use as an HIV-1 coreceptor
    • Doranz B.J.et al. A small-molecule inhibitor directed against the chemokine receptor CXCR4 prevents its use as an HIV-1 coreceptor. J. Exp. Med. 186:1997;1395-1400.
    • (1997) J. Exp. Med. , vol.186 , pp. 1395-1400
    • Doranz, B.J.1
  • 49
    • 14444282418 scopus 로고    scopus 로고
    • Inhibition of in vitro and in vivo HIV replication by a distamycin analogue that interferes with chemokine receptor function: A candidate for chemotherapeutic and microbicidal application
    • Howard O.M.Z.et al. Inhibition of in vitro and in vivo HIV replication by a distamycin analogue that interferes with chemokine receptor function. a candidate for chemotherapeutic and microbicidal application J. Med. Chem. 41:1998;2184-2193.
    • (1998) J. Med. Chem. , vol.41 , pp. 2184-2193
    • Howard, O.M.Z.1
  • 50
    • 0028209166 scopus 로고
    • Highly potent and selective inhibition of human immunodeficiency virus by the bicyclam derivative JM3100
    • DeClercq E.et al. Highly potent and selective inhibition of human immunodeficiency virus by the bicyclam derivative JM3100. Antimicrob. Agents Chemother. 38:1994;668-674.
    • (1994) Antimicrob. Agents Chemother. , vol.38 , pp. 668-674
    • Declercq, E.1
  • 51
    • 0030830661 scopus 로고    scopus 로고
    • Inhibition of T-tropic HIV strains by selective antagonization of the chemokine receptor CXCR4
    • Schols D.et al. Inhibition of T-tropic HIV strains by selective antagonization of the chemokine receptor CXCR4. J. Exp. Med. 186:1997;1383-1388.
    • (1997) J. Exp. Med. , vol.186 , pp. 1383-1388
    • Schols, D.1
  • 52
    • 0031891516 scopus 로고    scopus 로고
    • AMD3100, a small molecule inhibitor of HIV-1 entry via the CXCR4 co-receptor
    • Donzella G.A.et al. AMD3100, a small molecule inhibitor of HIV-1 entry via the CXCR4 co-receptor. Nat. Med. 4:1998;72-77.
    • (1998) Nat. Med. , vol.4 , pp. 72-77
    • Donzella, G.A.1
  • 53
    • 0031927202 scopus 로고    scopus 로고
    • Determinants for sensitivity of human immunodeficiency virus coreceptor CXCR4 to the bicyclam AND3100
    • Labrosse B.et al. Determinants for sensitivity of human immunodeficiency virus coreceptor CXCR4 to the bicyclam AND3100. J. Virol. 72:1998;6381-6388.
    • (1998) J. Virol. , vol.72 , pp. 6381-6388
    • Labrosse, B.1
  • 54
    • 0003973947 scopus 로고    scopus 로고
    • The molecular target of bicyclams, potent inhibitors of human immunodeficiency virus replication
    • Vereese K.D.et al. The molecular target of bicyclams, potent inhibitors of human immunodeficiency virus replication. J. Virol. 70:1996;689-696.
    • (1996) J. Virol. , vol.70 , pp. 689-696
    • Vereese, K.D.1
  • 55
    • 13044256383 scopus 로고    scopus 로고
    • A small-molecule, nonpeptide CCR5 antagonist with highly potent and selective anti-HIV-1 activity
    • Baba M.et al. A small-molecule, nonpeptide CCR5 antagonist with highly potent and selective anti-HIV-1 activity. Proc. Natl. Acad. Sci. U. S. A. 96:1999;5698-5703.
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.96 , pp. 5698-5703
    • Baba, M.1
  • 56
    • 0030970693 scopus 로고    scopus 로고
    • Core structure of gp41 from the HIV envelope glycoprotein
    • Chan D.C.et al. Core structure of gp41 from the HIV envelope glycoprotein. Cell. 89:1997;263-273.
    • (1997) Cell , vol.89 , pp. 263-273
    • Chan, D.C.1
  • 57
    • 0030962291 scopus 로고    scopus 로고
    • Atomic structure of the ectodomain from HIV-1 gp41
    • Weissenhorn W.et al. Atomic structure of the ectodomain from HIV-1 gp41. Nature. 387:1997;426-430.
    • (1997) Nature , vol.387 , pp. 426-430
    • Weissenhorn, W.1
  • 58
    • 0030780614 scopus 로고    scopus 로고
    • Atomic structure of a thermostable subdomain of HIV-1 gp41
    • Tan K.et al. Atomic structure of a thermostable subdomain of HIV-1 gp41. Proc. Natl. Acad. Sci. U. S. A. 94:1997;12303-12308.
    • (1997) Proc. Natl. Acad. Sci. U. S. A. , vol.94 , pp. 12303-12308
    • Tan, K.1
  • 59
    • 0026465468 scopus 로고
    • A synthetic peptide inhibitor of human immunodeficiency virus replication: Correlation between solution structure and viral inhibition
    • Wild C.T.et al. A synthetic peptide inhibitor of human immunodeficiency virus replication. correlation between solution structure and viral inhibition Proc. Natl. Acad. Sci. U. S. A. 89:1992;10537-10541.
    • (1992) Proc. Natl. Acad. Sci. U. S. A. , vol.89 , pp. 10537-10541
    • Wild, C.T.1
  • 60
    • 0027959493 scopus 로고
    • Peptides corresponding to a predictive α-helical domain of human immunodeficiency virus type 1 gp41 are potent inhibitors of virus infection
    • Wild C.et al. Peptides corresponding to a predictive α-helical domain of human immunodeficiency virus type 1 gp41 are potent inhibitors of virus infection. Proc. Natl. Acad. Sci. U. S. A. 91:1994;9770-9774.
    • (1994) Proc. Natl. Acad. Sci. U. S. A. , vol.91 , pp. 9770-9774
    • Wild, C.1
  • 61
    • 0028168944 scopus 로고
    • Structural rearrangements in the transmembrane glycoprotein after receptor binding
    • Matthews T.J.et al. Structural rearrangements in the transmembrane glycoprotein after receptor binding. Immunol. Rev. 1994;93-104.
    • (1994) Immunol. Rev. , pp. 93-104
    • Matthews, T.J.1
  • 62
    • 0031959601 scopus 로고    scopus 로고
    • Capture of an early fusion-active conformation of HIV-1 gp41
    • Furata R.A.et al. Capture of an early fusion-active conformation of HIV-1 gp41. Nat. Struct. Biol. 5:1998;276-279.
    • (1998) Nat. Struct. Biol. , vol.5 , pp. 276-279
    • Furata, R.A.1
  • 63
    • 0031883832 scopus 로고    scopus 로고
    • Determinants of human immunodeficiency virus type 1 resistance to gp41-derived inhibitory peptides
    • Rimsky L.T.et al. Determinants of human immunodeficiency virus type 1 resistance to gp41-derived inhibitory peptides. J. Virol. 72:1998;986-993.
    • (1998) J. Virol. , vol.72 , pp. 986-993
    • Rimsky, L.T.1
  • 64
    • 0033607028 scopus 로고    scopus 로고
    • Structure-based identification of small molecule antiviral compounds targeted to the gp41 core structure of the human immunodeficiency virus type 1
    • Debnath A.K.et al. Structure-based identification of small molecule antiviral compounds targeted to the gp41 core structure of the human immunodeficiency virus type 1. J. Med. Chem. 42:1999;3203-3209.
    • (1999) J. Med. Chem. , vol.42 , pp. 3203-3209
    • Debnath, A.K.1
  • 65
    • 0033214895 scopus 로고    scopus 로고
    • Inhibiting HIV-1 entry: Discovery of D-peptide inhibitors that target the gp41 coiled-coil pocket
    • Eckert D.M.et al. Inhibiting HIV-1 entry. discovery of D-peptide inhibitors that target the gp41 coiled-coil pocket Cell. 99:1999;103-115.
    • (1999) Cell , vol.99 , pp. 103-115
    • Eckert, D.M.1
  • 66
    • 0032876381 scopus 로고    scopus 로고
    • Selection of gp41-mediated HIV-1 cell entry inhibitors from biased combinatorial libraries of non-natural binding elements
    • Ferrer M.et al. Selection of gp41-mediated HIV-1 cell entry inhibitors from biased combinatorial libraries of non-natural binding elements. Nat. Struct. Biol. 6:1999;953-960.
    • (1999) Nat. Struct. Biol. , vol.6 , pp. 953-960
    • Ferrer, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.