메뉴 건너뛰기




Volumn 8, Issue 6, 2013, Pages

Interaction of Complement Factor H and Fibulin3 in Age-Related Macular Degeneration

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; COMPLEMENT FACTOR H; FIBULIN; FIBULIN 3; UNCLASSIFIED DRUG;

EID: 84879541874     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0068088     Document Type: Article
Times cited : (37)

References (59)
  • 1
    • 33751103471 scopus 로고    scopus 로고
    • Age-related macular degeneration-emerging pathogenetic and therapeutic concepts
    • Gehrs KM, Anderson DH, Johnson LV, Hageman GS, (2006) Age-related macular degeneration-emerging pathogenetic and therapeutic concepts. Ann Med 38: 450-471.
    • (2006) Ann Med , vol.38 , pp. 450-471
    • Gehrs, K.M.1    Anderson, D.H.2    Johnson, L.V.3    Hageman, G.S.4
  • 2
    • 0034832029 scopus 로고    scopus 로고
    • An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration
    • Hageman GS, Luthert PJ, Victor Chong NH, Johnson LV, Anderson DH, et al. (2001) An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration. Prog Retin Eye Res 20: 705-732.
    • (2001) Prog Retin Eye Res , vol.20 , pp. 705-732
    • Hageman, G.S.1    Luthert, P.J.2    Victor, C.N.H.3    Johnson, L.V.4    Anderson, D.H.5
  • 3
    • 0028934221 scopus 로고
    • An international classification and grading system for age-related maculopathy and age-related macular degeneration. The International ARM Epidemiological Study Group
    • Bird AC, Bressler NM, Bressler SB, Chisholm IH, Coscas G, et al. (1995) An international classification and grading system for age-related maculopathy and age-related macular degeneration. The International ARM Epidemiological Study Group. Surv Ophthalmol 39: 367-374.
    • (1995) Surv Ophthalmol , vol.39 , pp. 367-374
    • Bird, A.C.1    Bressler, N.M.2    Bressler, S.B.3    Chisholm, I.H.4    Coscas, G.5
  • 4
    • 84863726788 scopus 로고    scopus 로고
    • Consequences of oxidative stress in age-related macular degeneration
    • Jarrett SG, Boulton ME, (2012) Consequences of oxidative stress in age-related macular degeneration. Mol Aspects Med 33: 399-417.
    • (2012) Mol Aspects Med , vol.33 , pp. 399-417
    • Jarrett, S.G.1    Boulton, M.E.2
  • 5
    • 79952117474 scopus 로고    scopus 로고
    • Bisretinoids of RPE lipofuscin: trigger for complement activation in age-related macular degeneration
    • Sparrow JR, (2010) Bisretinoids of RPE lipofuscin: trigger for complement activation in age-related macular degeneration. Adv Exp Med Biol 703: 63-74.
    • (2010) Adv Exp Med Biol , vol.703 , pp. 63-74
    • Sparrow, J.R.1
  • 7
    • 34848832895 scopus 로고    scopus 로고
    • Overview of progress in the epidemiology of age-related macular degeneration
    • Klein R, (2007) Overview of progress in the epidemiology of age-related macular degeneration. Ophthalmic Epidemiol 14: 184-187.
    • (2007) Ophthalmic Epidemiol , vol.14 , pp. 184-187
    • Klein, R.1
  • 8
    • 0033756108 scopus 로고    scopus 로고
    • The role of the atherosclerotic process in the pathogenesis of age-related macular degeneration
    • Friedman E, (2000) The role of the atherosclerotic process in the pathogenesis of age-related macular degeneration. Am J Ophthalmol 130: 658-663.
    • (2000) Am J Ophthalmol , vol.130 , pp. 658-663
    • Friedman, E.1
  • 9
    • 1842478123 scopus 로고    scopus 로고
    • Current concepts in the pathogenesis of age-related macular degeneration
    • Zarbin MA, (2004) Current concepts in the pathogenesis of age-related macular degeneration. Arch Ophthalmol 122: 598-614.
    • (2004) Arch Ophthalmol , vol.122 , pp. 598-614
    • Zarbin, M.A.1
  • 10
    • 33847404037 scopus 로고    scopus 로고
    • Fibrosis and diseases of the eye
    • Friedlander M, (2007) Fibrosis and diseases of the eye. J Clin Invest 117: 576-586.
    • (2007) J Clin Invest , vol.117 , pp. 576-586
    • Friedlander, M.1
  • 11
    • 79952786337 scopus 로고    scopus 로고
    • DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration
    • Kaneko H, Dridi S, Tarallo V, Gelfand BD, Fowler BJ, et al. (2011) DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration. Nature 471: 325-330.
    • (2011) Nature , vol.471 , pp. 325-330
    • Kaneko, H.1    Dridi, S.2    Tarallo, V.3    Gelfand, B.D.4    Fowler, B.J.5
  • 12
    • 0036741098 scopus 로고    scopus 로고
    • A role for local inflammation in the formation of drusen in the aging eye
    • Anderson DH, Mullins RF, Hageman GS, Johnson LV, (2002) A role for local inflammation in the formation of drusen in the aging eye. Am J Ophthalmol 134: 411-431.
    • (2002) Am J Ophthalmol , vol.134 , pp. 411-431
    • Anderson, D.H.1    Mullins, R.F.2    Hageman, G.S.3    Johnson, L.V.4
  • 13
    • 1542297335 scopus 로고    scopus 로고
    • The epidemiology of age-related macular degeneration
    • Klein R, Peto T, Bird A, Vannewkirk MR, (2004) The epidemiology of age-related macular degeneration. Am J Ophthalmol 137: 486-495.
    • (2004) Am J Ophthalmol , vol.137 , pp. 486-495
    • Klein, R.1    Peto, T.2    Bird, A.3    Vannewkirk, M.R.4
  • 14
    • 11144258543 scopus 로고    scopus 로고
    • Drusen proteome analysis: an approach to the etiology of age-related macular degeneration
    • Crabb JW, Miyagi M, Gu X, Shadrach K, West KA, et al. (2002) Drusen proteome analysis: an approach to the etiology of age-related macular degeneration. Proc Natl Acad Sci U S A 99: 14682-14687.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 14682-14687
    • Crabb, J.W.1    Miyagi, M.2    Gu, X.3    Shadrach, K.4    West, K.A.5
  • 15
    • 0034012166 scopus 로고    scopus 로고
    • Drusen associated with aging and age-related macular degeneration contain proteins common to extracellular deposits associated with atherosclerosis, elastosis, amyloidosis, and dense deposit disease
    • Mullins RF, Russell SR, Anderson DH, Hageman GS, (2000) Drusen associated with aging and age-related macular degeneration contain proteins common to extracellular deposits associated with atherosclerosis, elastosis, amyloidosis, and dense deposit disease. Faseb J 14: 835-846.
    • (2000) Faseb J , vol.14 , pp. 835-846
    • Mullins, R.F.1    Russell, S.R.2    Anderson, D.H.3    Hageman, G.S.4
  • 17
    • 20244380171 scopus 로고    scopus 로고
    • Complement factor H polymorphism in age-related macular degeneration
    • Klein RJ, Zeiss C, Chew EY, Tsai JY, Sackler RS, et al. (2005) Complement factor H polymorphism in age-related macular degeneration. Science 308: 385-389.
    • (2005) Science , vol.308 , pp. 385-389
    • Klein, R.J.1    Zeiss, C.2    Chew, E.Y.3    Tsai, J.Y.4    Sackler, R.S.5
  • 18
    • 21044453724 scopus 로고    scopus 로고
    • A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration
    • Hageman GS, Anderson DH, Johnson LV, Hancox LS, Taiber AJ, et al. (2005) A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration. Proc Natl Acad Sci U S A 102: 7227-7232.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 7227-7232
    • Hageman, G.S.1    Anderson, D.H.2    Johnson, L.V.3    Hancox, L.S.4    Taiber, A.J.5
  • 19
    • 17244379811 scopus 로고    scopus 로고
    • Complement factor H polymorphism and age-related macular degeneration
    • Edwards AO, Ritter R III, Abel KJ, Manning A, Panhuysen C, et al. (2005) Complement factor H polymorphism and age-related macular degeneration. Science 308: 421-424.
    • (2005) Science , vol.308 , pp. 421-424
    • Edwards, A.O.1    Ritter III, R.2    Abel, K.J.3    Manning, A.4    Panhuysen, C.5
  • 20
    • 20244388812 scopus 로고    scopus 로고
    • Complement factor H variant increases the risk of age-related macular degeneration
    • Haines JL, Hauser MA, Schmidt S, Scott WK, Olson LM, et al. (2005) Complement factor H variant increases the risk of age-related macular degeneration. Science 308: 419-421.
    • (2005) Science , vol.308 , pp. 419-421
    • Haines, J.L.1    Hauser, M.A.2    Schmidt, S.3    Scott, W.K.4    Olson, L.M.5
  • 21
    • 33847153137 scopus 로고    scopus 로고
    • Extended haplotypes in the complement factor H (CFH) and CFH-related (CFHR) family of genes protect against age-related macular degeneration: characterization, ethnic distribution and evolutionary implications
    • Hageman GS, Hancox LS, Taiber AJ, Gehrs KM, Anderson DH, et al. (2006) Extended haplotypes in the complement factor H (CFH) and CFH-related (CFHR) family of genes protect against age-related macular degeneration: characterization, ethnic distribution and evolutionary implications. Ann Med 38: 592-604.
    • (2006) Ann Med , vol.38 , pp. 592-604
    • Hageman, G.S.1    Hancox, L.S.2    Taiber, A.J.3    Gehrs, K.M.4    Anderson, D.H.5
  • 22
    • 33749123246 scopus 로고    scopus 로고
    • A common CFH haplotype, with deletion of CFHR1 and CFHR3, is associated with lower risk of age-related macular degeneration
    • Hughes AE, Orr N, Esfandiary H, Diaz-Torres M, Goodship T, et al. (2006) A common CFH haplotype, with deletion of CFHR1 and CFHR3, is associated with lower risk of age-related macular degeneration. Nat Genet 38: 1173-1177.
    • (2006) Nat Genet , vol.38 , pp. 1173-1177
    • Hughes, A.E.1    Orr, N.2    Esfandiary, H.3    Diaz-Torres, M.4    Goodship, T.5
  • 23
    • 33751004690 scopus 로고    scopus 로고
    • A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration
    • Yang Z, Camp NJ, Sun H, Tong Z, Gibbs D, et al. (2006) A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration. Science 314: 992-993.
    • (2006) Science , vol.314 , pp. 992-993
    • Yang, Z.1    Camp, N.J.2    Sun, H.3    Tong, Z.4    Gibbs, D.5
  • 24
    • 36049042661 scopus 로고    scopus 로고
    • A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration
    • Kanda A, Chen W, Othman M, Branham KE, Brooks M, et al. (2007) A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration. Proc Natl Acad Sci U S A 104: 16227-16232.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 16227-16232
    • Kanda, A.1    Chen, W.2    Othman, M.3    Branham, K.E.4    Brooks, M.5
  • 25
    • 33645419787 scopus 로고    scopus 로고
    • Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration
    • Gold B, Merriam JE, Zernant J, Hancox LS, Taiber AJ, et al. (2006) Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration. Nat Genet 38: 458-462.
    • (2006) Nat Genet , vol.38 , pp. 458-462
    • Gold, B.1    Merriam, J.E.2    Zernant, J.3    Hancox, L.S.4    Taiber, A.J.5
  • 26
    • 34547764305 scopus 로고    scopus 로고
    • Complement C3 variant and the risk of age-related macular degeneration
    • Yates JR, Sepp T, Matharu BK, Khan JC, Thurlby DA, et al. (2007) Complement C3 variant and the risk of age-related macular degeneration. N Engl J Med 357: 553-561.
    • (2007) N Engl J Med , vol.357 , pp. 553-561
    • Yates, J.R.1    Sepp, T.2    Matharu, B.K.3    Khan, J.C.4    Thurlby, D.A.5
  • 27
    • 34948898131 scopus 로고    scopus 로고
    • CX3CR1-dependent subretinal microglia cell accumulation is associated with cardinal features of age-related macular degeneration
    • Combadiere C, Feumi C, Raoul W, Keller N, Rodero M, et al. (2007) CX3CR1-dependent subretinal microglia cell accumulation is associated with cardinal features of age-related macular degeneration. J Clin Invest 117: 2920-2928.
    • (2007) J Clin Invest , vol.117 , pp. 2920-2928
    • Combadiere, C.1    Feumi, C.2    Raoul, W.3    Keller, N.4    Rodero, M.5
  • 28
    • 77952147434 scopus 로고    scopus 로고
    • Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration
    • Chen W, Stambolian D, Edwards AO, Branham KE, Othman M, et al. (2010) Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration. Proc Natl Acad Sci U S A 107: 7401-7406.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 7401-7406
    • Chen, W.1    Stambolian, D.2    Edwards, A.O.3    Branham, K.E.4    Othman, M.5
  • 29
    • 85027939027 scopus 로고    scopus 로고
    • Systems-level analysis of age-related macular degeneration reveals global biomarkers and phenotype-specific functional networks
    • Newman AM, Gallo NB, Hancox LS, Miller NJ, Radeke CM, et al. (2012) Systems-level analysis of age-related macular degeneration reveals global biomarkers and phenotype-specific functional networks. Genome Med 4: 16.
    • (2012) Genome Med , vol.4 , pp. 16
    • Newman, A.M.1    Gallo, N.B.2    Hancox, L.S.3    Miller, N.J.4    Radeke, C.M.5
  • 31
    • 33751243644 scopus 로고    scopus 로고
    • Individuals homozygous for the age-related macular degeneration risk-conferring variant of complement factor H have elevated levels of CRP in the choroid
    • Johnson PT, Betts KE, Radeke MJ, Hageman GS, Anderson DH, et al. (2006) Individuals homozygous for the age-related macular degeneration risk-conferring variant of complement factor H have elevated levels of CRP in the choroid. Proc Natl Acad Sci U S A 103: 17456-17461.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 17456-17461
    • Johnson, P.T.1    Betts, K.E.2    Radeke, M.J.3    Hageman, G.S.4    Anderson, D.H.5
  • 32
    • 80052135068 scopus 로고    scopus 로고
    • C-reactive protein and complement factor H in aged human eyes and eyes with age-related macular degeneration
    • Bhutto IA, Baba T, Merges C, Juriasinghani V, McLeod DS, et al. (2011) C-reactive protein and complement factor H in aged human eyes and eyes with age-related macular degeneration. Br J Ophthalmol 95: 1323-1330.
    • (2011) Br J Ophthalmol , vol.95 , pp. 1323-1330
    • Bhutto, I.A.1    Baba, T.2    Merges, C.3    Juriasinghani, V.4    McLeod, D.S.5
  • 33
    • 36749004311 scopus 로고    scopus 로고
    • Complement factor H deficiency in aged mice causes retinal abnormalities and visual dysfunction
    • Coffey PJ, Gias C, McDermott CJ, Lundh P, Pickering MC, et al. (2007) Complement factor H deficiency in aged mice causes retinal abnormalities and visual dysfunction. Proc Natl Acad Sci U S A 104: 16651-16656.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 16651-16656
    • Coffey, P.J.1    Gias, C.2    McDermott, C.J.3    Lundh, P.4    Pickering, M.C.5
  • 34
    • 0034954060 scopus 로고    scopus 로고
    • Structure and composition of drusen associated with glomerulonephritis: implications for the role of complement activation in drusen biogenesis
    • Mullins RF, Aptsiauri N, Hageman GS, (2001) Structure and composition of drusen associated with glomerulonephritis: implications for the role of complement activation in drusen biogenesis. Eye (Lond) 15: 390-395.
    • (2001) Eye (Lond) , vol.15 , pp. 390-395
    • Mullins, R.F.1    Aptsiauri, N.2    Hageman, G.S.3
  • 35
    • 78149270873 scopus 로고    scopus 로고
    • An imbalance of human complement regulatory proteins CFHR1, CFHR3 and factor H influences risk for age-related macular degeneration (AMD)
    • Fritsche LG, Lauer N, Hartmann A, Stippa S, Keilhauer CN, et al. (2010) An imbalance of human complement regulatory proteins CFHR1, CFHR3 and factor H influences risk for age-related macular degeneration (AMD). Hum Mol Genet 19: 4694-4704.
    • (2010) Hum Mol Genet , vol.19 , pp. 4694-4704
    • Fritsche, L.G.1    Lauer, N.2    Hartmann, A.3    Stippa, S.4    Keilhauer, C.N.5
  • 36
    • 0030046574 scopus 로고    scopus 로고
    • In vitro folding of inclusion body proteins
    • Rudolph R, Lilie H, (1996) In vitro folding of inclusion body proteins. Faseb J 10: 49-56.
    • (1996) Faseb J , vol.10 , pp. 49-56
    • Rudolph, R.1    Lilie, H.2
  • 37
    • 34547102526 scopus 로고    scopus 로고
    • Structure shows that a glycosaminoglycan and protein recognition site in factor H is perturbed by age-related macular degeneration-linked single nucleotide polymorphism
    • Herbert AP, Deakin JA, Schmidt CQ, Blaum BS, Egan C, et al. (2007) Structure shows that a glycosaminoglycan and protein recognition site in factor H is perturbed by age-related macular degeneration-linked single nucleotide polymorphism. J Biol Chem 282: 18960-18968.
    • (2007) J Biol Chem , vol.282 , pp. 18960-18968
    • Herbert, A.P.1    Deakin, J.A.2    Schmidt, C.Q.3    Blaum, B.S.4    Egan, C.5
  • 38
    • 0029872876 scopus 로고    scopus 로고
    • ARPE-19, a human retinal pigment epithelial cell line with differentiated properties
    • Dunn KC, Aotaki-Keen AE, Putkey FR, Hjelmeland LM, (1996) ARPE-19, a human retinal pigment epithelial cell line with differentiated properties. Exp Eye Res 62: 155-169.
    • (1996) Exp Eye Res , vol.62 , pp. 155-169
    • Dunn, K.C.1    Aotaki-Keen, A.E.2    Putkey, F.R.3    Hjelmeland, L.M.4
  • 39
    • 0036792087 scopus 로고    scopus 로고
    • Aberrant accumulation of EFEMP1 underlies drusen formation in Malattia Leventinese and age-related macular degeneration
    • Marmorstein LY, Munier FL, Arsenijevic Y, Schorderet DF, McLaughlin PJ, et al. (2002) Aberrant accumulation of EFEMP1 underlies drusen formation in Malattia Leventinese and age-related macular degeneration. Proc Natl Acad Sci U S A 99: 13067-13072.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 13067-13072
    • Marmorstein, L.Y.1    Munier, F.L.2    Arsenijevic, Y.3    Schorderet, D.F.4    McLaughlin, P.J.5
  • 40
    • 0034714420 scopus 로고    scopus 로고
    • Genome-wide protein interaction maps using two-hybrid systems
    • Legrain P, Selig L, (2000) Genome-wide protein interaction maps using two-hybrid systems. FEBS Lett 480: 32-36.
    • (2000) FEBS Lett , vol.480 , pp. 32-36
    • Legrain, P.1    Selig, L.2
  • 41
    • 0037686257 scopus 로고    scopus 로고
    • Fibulins: a versatile family of extracellular matrix proteins
    • Timpl R, Sasaki T, Kostka G, Chu ML, (2003) Fibulins: a versatile family of extracellular matrix proteins. Nat Rev Mol Cell Biol 4: 479-489.
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 479-489
    • Timpl, R.1    Sasaki, T.2    Kostka, G.3    Chu, M.L.4
  • 42
    • 3142714511 scopus 로고    scopus 로고
    • Tissue inhibitor of metalloproteinases-3 (TIMP-3) is a binding partner of epithelial growth factor-containing fibulin-like extracellular matrix protein 1 (EFEMP1). Implications for macular degenerations
    • Klenotic PA, Munier FL, Marmorstein LY, Anand-Apte B, (2004) Tissue inhibitor of metalloproteinases-3 (TIMP-3) is a binding partner of epithelial growth factor-containing fibulin-like extracellular matrix protein 1 (EFEMP1). Implications for macular degenerations. J Biol Chem 279: 30469-30473.
    • (2004) J Biol Chem , vol.279 , pp. 30469-30473
    • Klenotic, P.A.1    Munier, F.L.2    Marmorstein, L.Y.3    Anand-Apte, B.4
  • 43
    • 0028097367 scopus 로고
    • Mutations in the tissue inhibitor of metalloproteinases-3 (TIMP3) in patients with Sorsby's fundus dystrophy
    • Weber BH, Vogt G, Pruett RC, Stohr H, Felbor U, (1994) Mutations in the tissue inhibitor of metalloproteinases-3 (TIMP3) in patients with Sorsby's fundus dystrophy. Nature Genetics 8: 352-356.
    • (1994) Nature Genetics , vol.8 , pp. 352-356
    • Weber, B.H.1    Vogt, G.2    Pruett, R.C.3    Stohr, H.4    Felbor, U.5
  • 44
    • 0034307355 scopus 로고    scopus 로고
    • Uses of lacZ to study gene function: evaluation of beta-galactosidase assays employed in the yeast two-hybrid system
    • Serebriiskii IG, Golemis EA, (2000) Uses of lacZ to study gene function: evaluation of beta-galactosidase assays employed in the yeast two-hybrid system. Anal Biochem 285: 1-15.
    • (2000) Anal Biochem , vol.285 , pp. 1-15
    • Serebriiskii, I.G.1    Golemis, E.A.2
  • 45
    • 70349973078 scopus 로고    scopus 로고
    • Functional aspects of drusen regression in age-related macular degeneration
    • Sallo FB, Rechtman E, Peto T, Stanescu-Segall D, Vogt G, et al. (2009) Functional aspects of drusen regression in age-related macular degeneration. Br J Ophthalmol 93: 1345-1350.
    • (2009) Br J Ophthalmol , vol.93 , pp. 1345-1350
    • Sallo, F.B.1    Rechtman, E.2    Peto, T.3    Stanescu-Segall, D.4    Vogt, G.5
  • 46
    • 33748325757 scopus 로고    scopus 로고
    • CFH haplotypes without the Y402H coding variant show strong association with susceptibility to age-related macular degeneration
    • Li M, Atmaca-Sonmez P, Othman M, Branham KE, Khanna R, et al. (2006) CFH haplotypes without the Y402H coding variant show strong association with susceptibility to age-related macular degeneration. Nat Genet 38: 1049-1054.
    • (2006) Nat Genet , vol.38 , pp. 1049-1054
    • Li, M.1    Atmaca-Sonmez, P.2    Othman, M.3    Branham, K.E.4    Khanna, R.5
  • 47
    • 33947214392 scopus 로고    scopus 로고
    • Y402H polymorphism of complement factor H affects binding affinity to C-reactive protein
    • Laine M, Jarva H, Seitsonen S, Haapasalo K, Lehtinen MJ, et al. (2007) Y402H polymorphism of complement factor H affects binding affinity to C-reactive protein. J Immunol 178: 3831-3836.
    • (2007) J Immunol , vol.178 , pp. 3831-3836
    • Laine, M.1    Jarva, H.2    Seitsonen, S.3    Haapasalo, K.4    Lehtinen, M.J.5
  • 48
    • 34948910047 scopus 로고    scopus 로고
    • Structural basis for complement factor H linked age-related macular degeneration
    • Prosser BE, Johnson S, Roversi P, Herbert AP, Blaum BS, et al. (2007) Structural basis for complement factor H linked age-related macular degeneration. J Exp Med 204: 2277-2283.
    • (2007) J Exp Med , vol.204 , pp. 2277-2283
    • Prosser, B.E.1    Johnson, S.2    Roversi, P.3    Herbert, A.P.4    Blaum, B.S.5
  • 49
    • 0033027071 scopus 로고    scopus 로고
    • A single EFEMP1 mutation associated with both Malattia Leventinese and Doyne honeycomb retinal dystrophy
    • Stone EM, Lotery AJ, Munier FL, Heon E, Piguet B, et al. (1999) A single EFEMP1 mutation associated with both Malattia Leventinese and Doyne honeycomb retinal dystrophy. Nat Genet 22: 199-202.
    • (1999) Nat Genet , vol.22 , pp. 199-202
    • Stone, E.M.1    Lotery, A.J.2    Munier, F.L.3    Heon, E.4    Piguet, B.5
  • 50
    • 34848894584 scopus 로고    scopus 로고
    • The R345W Mutation in EFEMP1 is Pathogenic, and Causes AMD-Like Deposits in Mice
    • Fu L, Garland D, Yang Z, Shukla D, Rajendran A, et al. (2007) The R345W Mutation in EFEMP1 is Pathogenic, and Causes AMD-Like Deposits in Mice. Hum Mol Genet.
    • (2007) Hum Mol Genet
    • Fu, L.1    Garland, D.2    Yang, Z.3    Shukla, D.4    Rajendran, A.5
  • 51
    • 34848820048 scopus 로고    scopus 로고
    • Formation and Progression of Sub-Retinal Pigment Epithelium Deposits in Efemp1 Mutation Knock-in Mice: A Model for the Early Pathogenic Course of Macular Degeneration
    • Marmorstein LY, McLaughlin PJ, Peachey NS, Sasaki T, Marmorstein AD (2007) Formation and Progression of Sub-Retinal Pigment Epithelium Deposits in Efemp1 Mutation Knock-in Mice: A Model for the Early Pathogenic Course of Macular Degeneration. Hum Mol Genet.
    • (2007) Hum Mol Genet
    • Marmorstein, L.Y.1    McLaughlin, P.J.2    Peachey, N.S.3    Sasaki, T.4    Marmorstein, A.D.5
  • 52
    • 67650529853 scopus 로고    scopus 로고
    • Latent transforming growth factor beta-binding proteins and fibulins compete for fibrillin-1 and exhibit exquisite specificities in binding sites
    • Ono RN, Sengle G, Charbonneau NL, Carlberg V, Bachinger HP, et al. (2009) Latent transforming growth factor beta-binding proteins and fibulins compete for fibrillin-1 and exhibit exquisite specificities in binding sites. J Biol Chem 284: 16872-16881.
    • (2009) J Biol Chem , vol.284 , pp. 16872-16881
    • Ono, R.N.1    Sengle, G.2    Charbonneau, N.L.3    Carlberg, V.4    Bachinger, H.P.5
  • 53
    • 3242719404 scopus 로고    scopus 로고
    • Missense variations in the fibulin 5 gene and age-related macular degeneration
    • Stone EM, Braun TA, Russell SR, Kuehn MH, Lotery AJ, et al. (2004) Missense variations in the fibulin 5 gene and age-related macular degeneration. N Engl J Med 351: 346-353.
    • (2004) N Engl J Med , vol.351 , pp. 346-353
    • Stone, E.M.1    Braun, T.A.2    Russell, S.R.3    Kuehn, M.H.4    Lotery, A.J.5
  • 54
    • 34047195173 scopus 로고    scopus 로고
    • Case-control genetic association study of fibulin-6 (FBLN6 or HMCN1) variants in age-related macular degeneration (AMD)
    • Fisher SA, Rivera A, Fritsche LG, Keilhauer CN, Lichtner P, et al. (2007) Case-control genetic association study of fibulin-6 (FBLN6 or HMCN1) variants in age-related macular degeneration (AMD). Hum Mutat 28: 406-413.
    • (2007) Hum Mutat , vol.28 , pp. 406-413
    • Fisher, S.A.1    Rivera, A.2    Fritsche, L.G.3    Keilhauer, C.N.4    Lichtner, P.5
  • 55
    • 75749140621 scopus 로고    scopus 로고
    • ARMS2 is a constituent of the extracellular matrix providing a link between familial and sporadic age-related macular degenerations
    • Kortvely E, Hauck SM, Duetsch G, Gloeckner CJ, Kremmer E, et al. (2010) ARMS2 is a constituent of the extracellular matrix providing a link between familial and sporadic age-related macular degenerations. Invest Ophthalmol Vis Sci 51: 79-88.
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , pp. 79-88
    • Kortvely, E.1    Hauck, S.M.2    Duetsch, G.3    Gloeckner, C.J.4    Kremmer, E.5
  • 56
    • 79960983554 scopus 로고    scopus 로고
    • Overexpression of HTRA1 leads to ultrastructural changes in the elastic layer of Bruch's membrane via cleavage of extracellular matrix components
    • Vierkotten S, Muether PS, Fauser S, (2011) Overexpression of HTRA1 leads to ultrastructural changes in the elastic layer of Bruch's membrane via cleavage of extracellular matrix components. PLoS ONE 6: e22959.
    • (2011) PLoS ONE , vol.6
    • Vierkotten, S.1    Muether, P.S.2    Fauser, S.3
  • 57
    • 78651247731 scopus 로고    scopus 로고
    • Genome-wide analysis of copy number variants in age-related macular degeneration
    • Meyer KJ, Davis LK, Schindler EI, Beck JS, Rudd DS, et al. (2011) Genome-wide analysis of copy number variants in age-related macular degeneration. Hum Genet 129: 91-100.
    • (2011) Hum Genet , vol.129 , pp. 91-100
    • Meyer, K.J.1    Davis, L.K.2    Schindler, E.I.3    Beck, J.S.4    Rudd, D.S.5
  • 58
    • 79961005068 scopus 로고    scopus 로고
    • Anti-amyloid therapy protects against retinal pigmented epithelium damage and vision loss in a model of age-related macular degeneration
    • Ding JD, Johnson LV, Herrmann R, Farsiu S, Smith SG, et al. (2011) Anti-amyloid therapy protects against retinal pigmented epithelium damage and vision loss in a model of age-related macular degeneration. Proc Natl Acad Sci U S A 108: E279-287.
    • (2011) Proc Natl Acad Sci U S A , vol.108
    • Ding, J.D.1    Johnson, L.V.2    Herrmann, R.3    Farsiu, S.4    Smith, S.G.5
  • 59
    • 77953799874 scopus 로고    scopus 로고
    • Biomarkers of inflammation and oxidative stress in atherosclerosis
    • Uno K, Nicholls SJ, (2010) Biomarkers of inflammation and oxidative stress in atherosclerosis. Biomark Med 4: 361-373.
    • (2010) Biomark Med , vol.4 , pp. 361-373
    • Uno, K.1    Nicholls, S.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.