-
1
-
-
0003964363
-
-
American Cancer Society American Cancer Society, GA, USA
-
American Cancer Society. Cancer Facts & Figures 2010. American Cancer Society, GA, USA (2010).
-
(2010)
Cancer Facts & Figures 2010
-
-
-
2
-
-
0038672688
-
Molecular targeting of VHL gene pathway in clear cell kidney cancer
-
Linehan WM. Molecular targeting of VHL gene pathway in clear cell kidney cancer. J. Urol. 170, 593 (2003).
-
(2003)
J. Urol
, vol.170
, pp. 593
-
-
Linehan, W.M.1
-
3
-
-
77958012311
-
Targeted therapies for non-clear renal cell carcinoma
-
Singer EA, Bratslavsky G, Linehan WM, Srinivasan R. Targeted therapies for non-clear renal cell carcinoma. Target. Oncol. 5(2), 119-129 (2010).
-
(2010)
Target. Oncol
, vol.5
, Issue.2
, pp. 119-129
-
-
Singer, E.A.1
Bratslavsky, G.2
Linehan, W.M.3
Srinivasan, R.4
-
4
-
-
77952263737
-
The genetic basis of kidney cancer: A metabolic disease
-
Linehan WM, Srinivasan R, Schmidt LS. The genetic basis of kidney cancer: a metabolic disease. Nat. Rev. Urol. 7(5), 277-285 (2010).
-
(2010)
Nat. Rev. Urol
, vol.7
, Issue.5
, pp. 277-285
-
-
Linehan, W.M.1
Srinivasan, R.2
Schmidt, L.S.3
-
5
-
-
0001221508
-
On respiratory impairment in cancer cells
-
Warburg O. On respiratory impairment in cancer cells. Science 124(3215), 269-270 (1956).
-
(1956)
Science
, vol.124
, Issue.3215
, pp. 269-270
-
-
Warburg, O.1
-
6
-
-
60249101138
-
The prime cause and prevention of cancer
-
Presented at: the Lindau, Germany
-
Warburg O. The prime cause and prevention of cancer. Presented at: the 17th Annual Lindau Nobel Laureate Meetings. Lindau, Germany (1967).
-
(1967)
17th Annual Lindau Nobel Laureate Meetings
-
-
Warburg, O.1
-
7
-
-
11444261260
-
Energy boost: The Warburg effect returns in a new theory of cancer
-
Garber K. Energy boost: the Warburg effect returns in a new theory of cancer. J. Natl Cancer Inst. 96(24), 1805-1806 (2004). (Pubitemid 40081310)
-
(2004)
Journal of the National Cancer Institute
, vol.96
, Issue.24
, pp. 1805-1806
-
-
Garber, K.1
-
8
-
-
0032581277
-
Role of HIF-1α in hypoxiamediated apoptosis, cell proliferation and tumour angiogenesis
-
DOI 10.1038/28867
-
Carmeliet P, Dor Y, Herbert JM et al. Role of HIF1? in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis. Nature 394(6692), 485-490 (1998). (Pubitemid 28373960)
-
(1998)
Nature
, vol.394
, Issue.6692
, pp. 485-490
-
-
Carmeliet, P.1
Dor, Y.2
Herber, J.-M.3
Fukumura, D.4
Brusselmans, K.5
Dewerchin, M.6
Neeman, M.7
Bono, F.8
Abramovitch, R.9
Maxwell, P.10
Koch, C.J.11
Ratcliffe, P.12
Moons, L.13
Jain, R.K.14
Collen, D.15
Keshet, E.16
-
9
-
-
0030816109
-
Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth
-
DOI 10.1073/pnas.94.15.8104
-
Maxwell PH, Dachs GU, Gleadle JM et al. Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth. Proc. Natl Acad. Sci. USA 94(15), 8104-8109 (1997). (Pubitemid 27343784)
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.15
, pp. 8104-8109
-
-
Maxwell, P.H.1
Dachs, G.U.2
Gleadle, J.M.3
Nicholls, L.G.4
Harris, A.L.5
Stratford, I.J.6
Hankinson, O.7
Pugh, C.W.8
Ratcliffe, P.J.9
-
10
-
-
2542561169
-
Akt stimulates aerobic glycolysis in cancer cells
-
DOI 10.1158/0008-5472.CAN-03-2904
-
Elstrom RL, Bauer DE, Buzzai M et al. Akt stimulates aerobic glycolysis in cancer cells. Cancer Res. 64(11), 3892-3899 (2004). (Pubitemid 38697301)
-
(2004)
Cancer Research
, vol.64
, Issue.11
, pp. 3892-3899
-
-
Elstrom, R.L.1
Bauer, D.E.2
Buzzai, M.3
Karnauskas, R.4
Harris, M.H.5
Plas, D.R.6
Zhuang, H.7
Cinalli, R.M.8
Alavi, A.9
Rudin, C.M.10
Thompson, C.B.11
-
11
-
-
33644614520
-
HIF1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia
-
Kim JW, Tchernyshyov I, Semenza GL, Dang CV. HIF1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia. Cell Metab. 3(3), 177-185 (2006).
-
(2006)
Cell Metab
, vol.3
, Issue.3
, pp. 177-185
-
-
Kim, J.W.1
Tchernyshyov, I.2
Semenza, G.L.3
Dang, C.V.4
-
12
-
-
0030921103
-
C-Myc transactivation of LDH-A: Implications for tumor metabolism and growth
-
DOI 10.1073/pnas.94.13.6658
-
Shim H, Dolde C, Lewis BC et al. c-Myc transactivation of LDH-A: implications for tumor metabolism and growth. Proc. Natl Acad. Sci. USA 94(13), 6658-6663 (1997). (Pubitemid 27281920)
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.13
, pp. 6658-6663
-
-
Shim, H.1
Dolde, C.2
Lewis, B.C.3
Wu, C.-S.4
Dang, G.5
Jungmann, R.A.6
Dalla-Favera, R.7
Dang, C.V.8
-
13
-
-
0345491599
-
Differential Roles of Hypoxia-Inducible Factor 1α (HIF-1α) and HIF-2α in Hypoxic Gene Regulation
-
DOI 10.1128/MCB.23.24.9361-9374.2003
-
Hu CJ, Wang LY, Chodosh LA, Keith B, Simon MC. Differential roles of hypoxiainducible factor 1? (HIF1?) and HIF-2? in hypoxic gene regulation. Mol. Cell. Biol. 23(24), 9361-9374 (2003). (Pubitemid 37499822)
-
(2003)
Molecular and Cellular Biology
, vol.23
, Issue.24
, pp. 9361-9374
-
-
Hu, C.-J.1
Wang, L.-Y.2
Chodosh, L.A.3
Keith, B.4
Simon, M.C.5
-
14
-
-
0027954044
-
Mutations of the VHL tumour suppressor gene in renal carcinoma
-
DOI 10.1038/ng0594-85
-
Gnarra JR, Tory K, Weng Y et al. Mutations of the VHL tumour suppressor gene in renal carcinoma. Nat. Genet. 7(1), 85-90 (1994). (Pubitemid 24232386)
-
(1994)
Nature Genetics
, vol.7
, Issue.1
, pp. 85-90
-
-
Gnarra, J.R.1
Tory, K.2
Weng, Y.3
Schmidt, L.4
Wei, M.H.5
Li, H.6
Latif, F.7
Liu, S.8
Chen, F.9
Duh, F.-M.10
Lubensky, I.11
Duan, D.R.12
Florence, C.13
Pozzatti, R.14
Walther, M.M.15
Bander, N.H.16
Grossman, H.B.17
Brauch, H.18
Pomer, S.19
Brooks, J.D.20
Isaacs, W.B.21
Lerman, M.I.22
Zbar, B.23
Linehan, W.M.24
more..
-
15
-
-
0028072991
-
Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma
-
DOI 10.1073/pnas.91.21.9700
-
Herman JG, Latif F, Weng Y et al. Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma. Proc. Natl Acad. Sci. USA 91(21), 9700-9704 (1994). (Pubitemid 24311875)
-
(1994)
Proceedings of the National Academy of Sciences of the United States of America
, vol.91
, Issue.21
, pp. 9700-9704
-
-
Herman, J.G.1
Latif, F.2
Weng, Y.3
Lerman, M.I.4
Zbar, B.5
Liu, S.6
Samid, D.7
Duan, D.-S.R.8
Gnarra, J.R.9
Linehan, W.M.10
Baylin, S.B.11
-
16
-
-
0027240519
-
Identification of the von Hippel-Lindau disease tumor suppressor gene
-
Latif F, Tory K, Gnarra J et al. Identification of the von Hippel-Lindau disease tumor suppressor gene. Science 260(5112), 1317-1320 (1993). (Pubitemid 23231974)
-
(1993)
Science
, vol.260
, Issue.5112
, pp. 1317-1320
-
-
Latif, F.1
Tory, K.2
Gnarra, J.3
Yao, M.4
Duh, F.-M.5
Orcutt, M.L.6
Stackhouse, T.7
Kuzmin, I.8
Modi, W.9
Geil, L.10
Schmidt, L.11
Zhou, F.12
Li, H.13
Ming Hui Wei14
Chen, F.15
Glenn, G.16
Choyke, P.17
Walther, M.M.18
Weng, Y.19
-
17
-
-
0033587146
-
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
-
DOI 10.1038/20459
-
Maxwell PH, Wiesener MS, Chang GW et al. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature 399(6733), 271-275 (1999). (Pubitemid 29246458)
-
(1999)
Nature
, vol.399
, Issue.6733
, pp. 271-275
-
-
Maxwell, P.H.1
Wlesener, M.S.2
Chang, G.-W.3
Clifford, S.C.4
Vaux, E.C.5
Cockman, M.E.6
Wykoff, C.C.7
Pugh, C.W.8
Maher, E.R.9
Ratcliffe, P.J.10
-
18
-
-
0035937715
-
Regulation of glut1 mRNA by hypoxiainducible factor-1. Interaction between H-ras and hypoxia
-
Chen C, Pore N, Behrooz A et al. Regulation of glut1 mRNA by hypoxiainducible factor-1. Interaction between H-ras and hypoxia. J. biol. chem. 276, 9519 (2001).
-
(2001)
J. Biol. Chem
, vol.276
, pp. 9519
-
-
Chen, C.1
Pore, N.2
Behrooz, A.3
-
19
-
-
2942701935
-
Evaluation of Myc E-box phylogenetic footprints in glycolytic genes by chromatin immunoprecipitation assays
-
DOI 10.1128/MCB.24.13.5923-5936.2004
-
Kim JW, Zeller KI, Wang Y et al. Evaluation of myc E-box phylogenetic footprints in glycolytic genes by chromatin immunoprecipitation assays. Mol. Cell. Biol. 24(13), 5923-5936 (2004). (Pubitemid 38787976)
-
(2004)
Molecular and Cellular Biology
, vol.24
, Issue.13
, pp. 5923-5936
-
-
Kim, J.-W.1
Zeller, K.I.2
Wang, Y.3
Jegga, A.G.4
Aronow, B.J.5
O'Donnell, K.A.6
Dang, C.V.7
-
20
-
-
0034698178
-
Deregulation of glucose transporter 1 and glycolytic gene expression by c-Myc
-
DOI 10.1074/jbc.C000023200
-
Osthus RC, Shim H, Kim S et al. Deregulation of glucose transporter 1 and glycolytic gene expression by c-Myc. J. Biol. Chem. 275(29), 21797-21800 (2000). (Pubitemid 30621745)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.29
, pp. 21797-21800
-
-
Osthus, R.C.1
Shim, H.2
Kim, S.3
Li, Q.4
Reddy, R.5
Mukherjee, M.6
Xu, Y.7
Wonsey, D.8
Lee, L.A.9
Dang, C.V.10
-
21
-
-
42249099171
-
Loss of complex I due to mitochondrial DNA mutations in renal oncocytoma
-
DOI 10.1158/1078-0432.CCR-07-4131
-
Mayr JA, Meierhofer D, Zimmermann F et al. Loss of complex I due to mitochondrial DNA mutations in renal oncocytoma. Clin. Cancer Res. 14(8), 2270-2275 (2008). (Pubitemid 351551057)
-
(2008)
Clinical Cancer Research
, vol.14
, Issue.8
, pp. 2270-2275
-
-
Mayr, J.A.1
Meierhofer, D.2
Zimmermann, F.3
Feichtinger, R.4
Kogler, C.5
Ratschek, M.6
Schmeller, N.7
Sperl, W.8
Kofler, B.9
-
22
-
-
0029865312
-
Detection of mitochondrial genome depletion by a novel cDNA in renal cell carcinoma
-
Selvanayagam P, Rajaraman S. Detection of mitochondrial genome depletion by a novel cDNA in renal cell carcinoma. Lab. Invest. 74(3), 592-599 (1996). (Pubitemid 26105720)
-
(1996)
Laboratory Investigation
, vol.74
, Issue.3
, pp. 592-599
-
-
Selvanayagam, P.1
Rajaraman, S.2
-
23
-
-
0030030467
-
Novel mitochondrial DNA deletion found in a renal cell carcinoma
-
DOI 10.1002/(SICI)1098-2264(199602)15:2<95::AID-GCC3>3.0.CO;2-Z
-
Horton TM, Petros JA, Heddi A et al. Novel mitochondrial DNA deletion found in a renal cell carcinoma. Genes Chromosomes Cancer 15(2), 95-101 (1996). (Pubitemid 26048409)
-
(1996)
Genes Chromosomes and Cancer
, vol.15
, Issue.2
, pp. 95-101
-
-
Horton, T.M.1
Petros, J.A.2
Heddi, A.3
Shoffner, J.4
Kaufman, A.E.5
Graham Jr., S.D.6
Gramlich, T.7
Wallace, D.C.8
-
24
-
-
70350728803
-
MYC-induced cancer cell energy metabolism and therapeutic opportunities
-
Dang CV, Le A, Gao P. MYC-induced cancer cell energy metabolism and therapeutic opportunities. Clin. Cancer Res. 15(21), 6479-6483 (2009).
-
(2009)
Clin. Cancer Res
, vol.15
, Issue.21
, pp. 6479-6483
-
-
Dang, C.V.1
Le Gao A, P.2
-
25
-
-
33745234207
-
Increased risk of cancer in patients with fumarate hydratase germline mutation
-
DOI 10.1136/jmg.2005.036400
-
Lehtonen HJ, Kiuru M, Ylisaukko-Oja SK et al. Increased risk of cancer in patients with fumarate hydratase germline mutation. J. Med. Genet. 43(6), 523-526 (2006). (Pubitemid 43927328)
-
(2006)
Journal of Medical Genetics
, vol.43
, Issue.6
, pp. 523-526
-
-
Lehtonen, H.J.1
Kiuru, M.2
Ylisaukko-Oja, S.K.3
Salovaara, R.4
Herva, R.5
Koivisto, P.A.6
Vierimaa, O.7
Aittomaki, K.8
Pukkala, E.9
Launonen, V.10
Aaltonen, L.A.11
-
26
-
-
34748836454
-
The morphologic spectrum of kidney tumors in hereditary leiomyomatosis and renal cell carcinoma (HLRCC) syndrome
-
DOI 10.1097/PAS.0b013e31804375b8, PII 0000047820071000000016
-
Merino MJ, Torres-Cabala C, Pinto P, Linehan WM. The morphologic spectrum of kidney tumors in hereditary leiomyomatosis and renal cell carcinoma (HLRCC) syndrome. Am. J. Surg. Pathol. 31(10), 1578-1585 (2007). (Pubitemid 47482473)
-
(2007)
American Journal of Surgical Pathology
, vol.31
, Issue.10
, pp. 1578-1585
-
-
Merino, M.J.1
Torres-Cabala, C.2
Pinto, P.3
Marston Linehan, W.4
-
27
-
-
0015857584
-
Cutaneous leiomyomata with uterine leiomyomata
-
Reed WB, Walker R, Horowitz R. Cutaneous leiomyomata with uterine leiomyomata. Acta Derm. Venereol. 53(5), 409-416 (1973).
-
(1973)
Acta Derm. Venereol
, vol.53
, Issue.5
, pp. 409-416
-
-
Reed, W.B.1
Walker, R.2
Horowitz, R.3
-
28
-
-
0035853166
-
Inherited susceptibility to uterine leiomyomas and renal cell cancer
-
DOI 10.1073/pnas.051633798
-
Launonen V, Vierimaa O, Kiuru M et al. Inherited susceptibility to uterine leiomyomas and renal cell cancer. Proc. Natl Acad. Sci. USA 98(6), 3387-3392 (2001). (Pubitemid 32220855)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.6
, pp. 3387-3392
-
-
Launonen, V.1
Vierimaa, O.2
Kiuru, M.3
Isola, J.4
Roth, S.5
Pukkala, E.6
Sistonen, P.7
Herva, R.8
Aaltonen, L.A.9
-
29
-
-
0035007528
-
Localization of a gene (MCUL1) for multiple cutaneous leiomyomata and uterine fibroids to chromosome 1q42.3-q43
-
DOI 10.1086/320124
-
Alam NA, Bevan S, Churchman M et al. Localization of a gene (MCUL1) for multiple cutaneous leiomyomata and uterine fibroids to chromosome 1q42.3-q43. Am. J. Hum. Genet. 68(5), 1264-1269 (2001). (Pubitemid 32424424)
-
(2001)
American Journal of Human Genetics
, vol.68
, Issue.5
, pp. 1264-1269
-
-
Alam, N.A.1
Bevan, S.2
Churchman, M.3
Barclay, E.4
Barker, K.5
Jaeger, E.E.M.6
Nelson, H.M.7
Healy, E.8
Pembroke, A.C.9
Friedmann, P.S.10
Dalziel, K.11
Calonje, E.12
Anderson, J.13
August, P.J.14
Davies, M.G.15
Felix, R.16
Munro, C.S.17
Murdoch, M.18
Rendall, J.19
Kennedy, S.20
Leigh, I.M.21
Kelsell, D.P.22
Tomlinson, I.P.M.23
Houlston, R.S.24
more..
-
30
-
-
80052572942
-
The glycolytic shift in fumaratehydratase-deficient kidney cancer lowers AMPK levels, increases anabolic propensities and lowers cellular iron levels
-
Tong WH, Sourbier C, Kovtunovych G et al. The glycolytic shift in fumaratehydratase-deficient kidney cancer lowers AMPK levels, increases anabolic propensities and lowers cellular iron levels. Cancer Cell 20(3), 315-327 (2011).
-
(2011)
Cancer Cell
, vol.20
, Issue.3
, pp. 315-327
-
-
Tong, W.H.1
Sourbier, C.2
Kovtunovych, G.3
-
31
-
-
34248336258
-
Hereditary leiomyomatosis and renal cell cancer: A syndrome associated with an aggressive form of inherited renal cancer
-
Grubb RL 3rd, Franks ME, Toro J et al. Hereditary leiomyomatosis and renal cell cancer: a syndrome associated with an aggressive form of inherited renal cancer. J. Urol. 177, 2074 (2007).
-
(2007)
J. Urol
, vol.177
, pp. 2074
-
-
Grubb III, R.L.1
Franks, M.E.2
Toro, J.3
-
32
-
-
0034964421
-
Gene mutations in the succinate dehydrogenase subunit SDHB cause susceptibility to familial pheochromocytoma and to familial paraganglioma
-
DOI 10.1086/321282
-
Astuti D, Latif F, Dallol A et al. Gene mutations in the succinate dehydrogenase subunit SDHB cause susceptibility to familial pheochromocytoma and to familial paraganglioma. Am. J. Hum. Genet. 69(1), 49-54 (2001). (Pubitemid 32614017)
-
(2001)
American Journal of Human Genetics
, vol.69
, Issue.1
, pp. 49-54
-
-
Astuti, D.1
Latif, F.2
Dallol, A.3
Dahia, P.L.M.4
Douglas, F.5
George, E.6
Skoldberg, F.7
Husebye, E.S.8
Eng, C.9
Maher, E.R.10
-
33
-
-
0034602950
-
Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma
-
DOI 10.1126/science.287.5454.848
-
Baysal BE, Ferrell RE, Willett-Brozick JE et al. Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma. Science 287(5454), 848-851 (2000). (Pubitemid 30084326)
-
(2000)
Science
, vol.287
, Issue.5454
, pp. 848-851
-
-
Baysal, B.E.1
Ferrell, R.E.2
Willett-Brozick, J.E.3
Lawrence, E.C.4
Myssiorek, D.5
Bosch, A.6
Van Der Mey, A.7
Taschner, P.E.M.8
Rubinstein, W.S.9
Myers, E.N.10
Richard III, C.W.11
Cornelisse, C.J.12
Devilee, P.13
Devlin, B.14
-
34
-
-
0033767445
-
Mutations in SDHC cause autosomal dominant paraganglioma, type 3
-
Niemann S, Müller U. Mutations in SDHC cause autosomal dominant paraganglioma, type 3. Nat. Genet. 26(3), 268-270 (2000).
-
(2000)
Nat. Genet
, vol.26
, Issue.3
, pp. 268-270
-
-
Niemann, S.1
Müller, U.2
-
35
-
-
51749113159
-
Germline SDHB mutations and familial renal cell carcinoma
-
Ricketts C, Woodward ER, Killick P et al. Germline SDHB mutations and familial renal cell carcinoma. J. Natl Cancer Inst. 100(17), 1260-1262 (2008).
-
(2008)
J. Natl Cancer Inst
, vol.100
, Issue.17
, pp. 1260-1262
-
-
Ricketts, C.1
Woodward, E.R.2
Killick, P.3
-
36
-
-
9144249602
-
Early-Onset Renal Cell Carcinoma as a Novel Extraparaganglial Component of SDHB-Associated Heritable Paraganglioma
-
DOI 10.1086/381054
-
Vanharanta S, Buchta M, McWhinney SR et al. Early-onset renal cell carcinoma as a novel extraparaganglial component of SDHB-associated heritable paraganglioma. Am. J. Hum. Genet. 74(1), 153-159 (2004). (Pubitemid 38085246)
-
(2004)
American Journal of Human Genetics
, vol.74
, Issue.1
, pp. 153-159
-
-
Vanharanta, S.1
Buchta, M.2
McWhinney, S.R.3
Virta, S.K.4
Peczkowska, M.5
Morrison, C.D.6
Lehtonen, R.7
Januszewicz, A.8
Jarvinen, H.9
Juhola, M.10
Mecklin, J.-P.11
Pukkala, E.12
Herva, R.13
Kiuru, M.14
Nupponen, N.N.15
Aaltonen, L.A.16
Neumann, H.P.H.17
Eng, C.18
-
37
-
-
77952275926
-
Long-term management of bilateral, multifocal, recurrent renal carcinoma
-
Bratslavsky G, Linehan WM. Long-term management of bilateral, multifocal, recurrent renal carcinoma. Nat. Rev. Urol. 7(5), 267-275 (2010).
-
(2010)
Nat. Rev. Urol
, vol.7
, Issue.5
, pp. 267-275
-
-
Bratslavsky, G.1
Linehan, W.M.2
-
38
-
-
84869080815
-
Succinate dehydrogenase kidney cancer: An aggressive example of the Warburg effect in cancer
-
Ricketts CJ, Shuch B, Vocke CD et al. Succinate dehydrogenase kidney cancer: an aggressive example of the Warburg effect in cancer. J. Urol. 188(6), 2063-2071 (2012).
-
(2012)
J. Urol
, vol.188
, Issue.6
, pp. 2063-2071
-
-
Ricketts, C.J.1
Shuch, B.2
Vocke, C.D.3
-
39
-
-
80053373522
-
Renal tumors associated with germline SDHB mutation show distinctive morphology
-
Gill AJ, Pachter NS, Chou A et al. Renal tumors associated with germline SDHB mutation show distinctive morphology. Am. J. Surg. Pathol. 35(10), 1578-1585 (2011).
-
(2011)
Am. J. Surg. Pathol
, vol.35
, Issue.10
, pp. 1578-1585
-
-
Gill, A.J.1
Pachter, N.S.2
Chou, A.3
-
40
-
-
23644448721
-
HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: Novel role of fumarate in regulation of HIF stability
-
DOI 10.1016/j.ccr.2005.06.017, PII S1535610805002266
-
Isaacs JS, Jung YJ, Mole DR et al. HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stability. Cancer Cell 8(2), 143-153 (2005). (Pubitemid 41132743)
-
(2005)
Cancer Cell
, vol.8
, Issue.2
, pp. 143-153
-
-
Isaacs, J.S.1
Yun, J.J.2
Mole, D.R.3
Lee, S.4
Torres-Cabala, C.5
Chung, Y.-L.6
Merino, M.7
Trepel, J.8
Zbar, B.9
Toro, J.10
Ratcliffe, P.J.11
Linehan, W.M.12
Neckers, L.13
-
41
-
-
19944433653
-
Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-α prolyl hydroxylase
-
DOI 10.1016/j.ccr.2004.11.022, PII S153561080400368X
-
Selak MA, Armour SM, MacKenzie ED et al. Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-? prolyl hydroxylase. Cancer Cell 7(1), 77-85 (2005). (Pubitemid 40126384)
-
(2005)
Cancer Cell
, vol.7
, Issue.1
, pp. 77-85
-
-
Selak, M.A.1
Armour, S.M.2
MacKenzie, E.D.3
Boulahbel, H.4
Watson, D.G.5
Mansfield, K.D.6
Pan, Y.7
Simon, M.C.8
Thompson, C.B.9
Gottlieb, E.10
-
42
-
-
78650990540
-
The mammalian target of rapamycin pathway is widely activated without PTEN deletion in renal cell carcinoma metastases
-
Abou Youssif T, Fahmy MA, Koumakpayi IH et al. The mammalian target of rapamycin pathway is widely activated without PTEN deletion in renal cell carcinoma metastases. Cancer 117(2), 290-300 (2011).
-
(2011)
Cancer
, vol.117
, Issue.2
, pp. 290-300
-
-
Abou Youssif, T.1
Fahmy, M.A.2
Koumakpayi, I.H.3
-
43
-
-
21344446791
-
Akt activation in renal cell carcinoma: Contribution of a decreased PTEN expression and the induction of apoptosis by an Akt inhibitor
-
DOI 10.1093/annonc/mdi182
-
Hara S, Oya M, Mizuno R, Horiguchi A, Marumo K, Murai M. Akt activation in renal cell carcinoma: contribution of a decreased PTEN expression and the induction of apoptosis by an Akt inhibitor. Ann. Oncol. 16(6), 928-933 (2005). (Pubitemid 40903919)
-
(2005)
Annals of Oncology
, vol.16
, Issue.6
, pp. 928-933
-
-
Hara, S.1
Oya, M.2
Mizuno, R.3
Horiguchi, A.4
Marumo, K.5
Murai, M.6
-
44
-
-
34249085992
-
Prognostic relevance of the mTOR pathway in renal cell carcinoma: Implications for molecular patient selection for targeted therapy
-
DOI 10.1002/cncr.22677
-
Pantuck AJ, Seligson DB, Klatte T et al. Prognostic relevance of the mTOR pathway in renal cell carcinoma: implications for molecular patient selection for targeted therapy. Cancer 109(11), 2257-2267 (2007). (Pubitemid 46801555)
-
(2007)
Cancer
, vol.109
, Issue.11
, pp. 2257-2267
-
-
Pantuck, A.J.1
Seligson, D.B.2
Klatte, T.3
Yu, H.4
Leppert, J.T.5
Moore, L.6
O'Toole, T.7
Gibbons, J.8
Belldegrun, A.S.9
Figlin, R.A.10
-
45
-
-
33750293584
-
Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling
-
DOI 10.1073/pnas.0603781103
-
Baba M, Hong SB, Sharma N et al. Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling. Proc. Natl Acad. Sci. USA 103(42), 15552-15557 (2006). (Pubitemid 44625630)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.42
, pp. 15552-15557
-
-
Baba, M.1
Hong, S.-B.2
Sharma, N.3
Warren, M.B.4
Nickerson, M.L.5
Iwamatsu, A.6
Esposito, D.7
Gillette, W.K.8
Hopkins III, R.F.9
Hartley, J.L.10
Furihata, M.11
Oishi, S.12
Zhen, W.13
Burke Jr., T.R.14
Linehan, W.M.15
Schmidt, L.S.16
Zbar, B.17
-
46
-
-
73249138930
-
Homozygous loss of BHD causes early embryonic lethality and kidney tumor development with activation of mTORC1 and mTORC2
-
Hasumi Y, Baba M, Ajima R et al. Homozygous loss of BHD causes early embryonic lethality and kidney tumor development with activation of mTORC1 and mTORC2. Proc. Natl Acad. Sci. USA 106(44), 18722-18727 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, Issue.44
, pp. 18722-18727
-
-
Hasumi, Y.1
Baba, M.2
Ajima, R.3
-
47
-
-
67651204610
-
Fumarate hydratase deficiency in renal cancer induces glycolytic addiction and hypoxia-inducible transcription factor 1? stabilization by glucose-dependent generation of reactive oxygen species
-
Sudarshan S, Sourbier C, Kong HS et al. Fumarate hydratase deficiency in renal cancer induces glycolytic addiction and hypoxia-inducible transcription factor 1? stabilization by glucose-dependent generation of reactive oxygen species. Mol. Cell. Biol. 29(15), 4080-4090 (2009).
-
(2009)
Mol. Cell. Biol
, vol.29
, Issue.15
, pp. 4080-4090
-
-
Sudarshan, S.1
Sourbier, C.2
Kong, H.S.3
-
48
-
-
79952501323
-
SIRT3 opposes reprogramming of cancer cell metabolism through HIF1a destabilization
-
Finley LW, Carracedo A, Lee J et al. SIRT3 opposes reprogramming of cancer cell metabolism through HIF1a destabilization. Cancer Cell 19(3), 416-428 (2011).
-
(2011)
Cancer Cell
, vol.19
, Issue.3
, pp. 416-428
-
-
Finley, L.W.1
Carracedo, A.2
Lee, J.3
-
49
-
-
67650085650
-
The role of cellular oxidative stress in regulating glycolysis energy metabolism in hepatoma cells
-
Shi DY, Xie FZ, Zhai C, Stern JS, Liu Y, Liu SL. The role of cellular oxidative stress in regulating glycolysis energy metabolism in hepatoma cells. Mol. Cancer 8, 32 (2009).
-
(2009)
Mol. Cancer
, vol.8
, pp. 32
-
-
Shi, D.Y.1
Xie, F.Z.2
Zhai, C.3
Stern, J.S.4
Liu, Y.5
Liu, S.L.6
-
50
-
-
0037364314
-
A role for mitochondrial enzymes in inherited neoplasia and beyond
-
DOI 10.1038/nrc1013
-
Eng C, Kiuru M, Fernandez MJ, Aaltonen LA. A role for mitochondrial enzymes in inherited neoplasia and beyond. Nat. Rev. Cancer 3(3), 193-202 (2003). (Pubitemid 37328871)
-
(2003)
Nature Reviews Cancer
, vol.3
, Issue.3
, pp. 193-202
-
-
Eng, C.1
Kiuru, M.2
Fernandez, M.J.3
Aaltonen, L.A.4
-
51
-
-
36249005491
-
Succinate inhibition of α-ketoglutarate-dependent enzymes in a yeast model of paraganglioma
-
DOI 10.1093/hmg/ddm275
-
Smith EH, Janknecht R, Maher LJ 3rd. Succinate inhibition of ?-ketoglutaratedependent enzymes in a yeast model of paraganglioma. Hum. Mol. Genet. 16(24), 3136-3148 (2007). (Pubitemid 350131331)
-
(2007)
Human Molecular Genetics
, vol.16
, Issue.24
, pp. 3136-3148
-
-
Smith, E.H.1
Janknecht, R.2
Maher III, J.L.3
-
52
-
-
34047167041
-
Targeted inactivation of Fh1 causes proliferative renal cyst development and activation of the hypoxia pathway
-
DOI 10.1016/j.ccr.2007.02.005, PII S153561080700058X
-
Pollard PJ, Spencer-Dene B, Shukla D et al. Targeted inactivation of fh1 causes proliferative renal cyst development and activation of the hypoxia pathway. Cancer Cell 11(4), 311-319 (2007). (Pubitemid 46518311)
-
(2007)
Cancer Cell
, vol.11
, Issue.4
, pp. 311-319
-
-
Pollard, P.J.1
Spencer-Dene, B.2
Shukla, D.3
Howarth, K.4
Nye, E.5
El-Bahrawy, M.6
Deheragoda, M.7
Joannou, M.8
McDonald, S.9
Martin, A.10
Igarashi, P.11
Varsani-Brown, S.12
Rosewell, I.13
Poulsom, R.14
Maxwell, P.15
Stamp, G.W.16
Tomlinson, I.P.M.17
-
53
-
-
80054767730
-
Renal cyst formation in Fh1-deficient mice is independent of the Hif/Phd pathway: Roles for fumarate in KEAP1 succination and Nrf2 signaling
-
Adam J, Hatipoglu E, O'Flaherty L et al. Renal cyst formation in Fh1-deficient mice is independent of the Hif/Phd pathway: roles for fumarate in KEAP1 succination and Nrf2 signaling. Cancer Cell 20(4), 524-537 (2011).
-
(2011)
Cancer Cell
, vol.20
, Issue.4
, pp. 524-537
-
-
Adam, J.1
Hatipoglu, E.2
O'Flaherty, L.3
-
54
-
-
80054772589
-
An antioxidant response phenotype shared between hereditary and sporadic type 2 papillary renal cell carcinoma
-
Ooi A, Wong JC, Petillo D et al. An antioxidant response phenotype shared between hereditary and sporadic type 2 papillary renal cell carcinoma. Cancer Cell 20(4), 511-523 (2011).
-
(2011)
Cancer Cell
, vol.20
, Issue.4
, pp. 511-523
-
-
Ooi, A.1
Wong, J.C.2
Petillo, D.3
-
55
-
-
84863764614
-
Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming
-
Mitsuishi Y, Taguchi K, Kawatani Y et al. Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming. Cancer Cell 22(1), 66-79 (2012).
-
(2012)
Cancer Cell
, vol.22
, Issue.1
, pp. 66-79
-
-
Mitsuishi, Y.1
Taguchi, K.2
Kawatani, Y.3
-
56
-
-
79961215490
-
Targeting GLUT1 and the Warburg effect in renal cell carcinoma by chemical synthetic lethality
-
Chan DA, Sutphin PD, Nguyen P et al. Targeting GLUT1 and the Warburg effect in renal cell carcinoma by chemical synthetic lethality. Sci. Transl. Med. 3(94), 94ra70 (2011).
-
(2011)
Sci. Transl. Med
, vol.3
, Issue.94
-
-
Chan, D.A.1
Sutphin, P.D.2
Nguyen, P.3
-
57
-
-
0022930036
-
2-type isozymes of rat pyruvate kinase are produced from the same gene by alternative RNA splicing
-
Noguchi T, Inoue H, Tanaka T. The M1-and M2-type isozymes of rat pyruvate kinase are produced from the same gene by alternative RNA splicing. J. Biol. Chem. 261(29), 13807-13812 (1986). (Pubitemid 17196407)
-
(1986)
Journal of Biological Chemistry
, vol.261
, Issue.29
, pp. 13807-13812
-
-
Noguchi, T.1
Inoue, H.2
Tanaka, T.3
-
58
-
-
23044500915
-
Pyruvate kinase type M2 and its role in tumor growth and spreading
-
DOI 10.1016/j.semcancer.2005.04.009, PII S1044579X0500026X, Tumor Metabolome
-
Mazurek S, Boschek CB, Hugo F, Eigenbrodt E. Pyruvate kinase type M2 and its role in tumor growth and spreading. Semin. Cancer Biol. 15(4), 300-308 (2005). (Pubitemid 41058775)
-
(2005)
Seminars in Cancer Biology
, vol.15
, Issue.4
, pp. 300-308
-
-
Mazurek, S.1
Boschek, C.B.2
Hugo, F.3
Eigenbrodt, E.4
-
59
-
-
40749163248
-
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
-
DOI 10.1038/nature06734, PII NATURE06734
-
Christofk HR, Vander Heiden MG, Harris MH et al. The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth. Nature 452(7184), 230-233 (2008). (Pubitemid 351380249)
-
(2008)
Nature
, vol.452
, Issue.7184
, pp. 230-233
-
-
Christofk, H.R.1
Vander Heiden, M.G.2
Harris, M.H.3
Ramanathan, A.4
Gerszten, R.E.5
Wei, R.6
Fleming, M.D.7
Schreiber, S.L.8
Cantley, L.C.9
-
60
-
-
79957567239
-
Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1
-
Luo W, Hu H, Chang R et al. Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1. Cell 145(5), 732-744 (2011).
-
(2011)
Cell
, vol.145
, Issue.5
, pp. 732-744
-
-
Luo, W.1
Hu, H.2
Chang, R.3
-
61
-
-
0036249158
-
Tumor M2-pyruvate kinase in lung cancer patients: Immunohistochemical detection and disease monitoring
-
Schneider J, Neu K, Grimm H, Velcovsky HG, Weisse G, Eigenbrodt E. Tumor M2-pyruvate kinase in lung cancer patients: immunohistochemical detection and disease monitoring. Anticancer Res. 22(1A), 311-318 (2002). (Pubitemid 34475318)
-
(2002)
Anticancer Research
, vol.22
, Issue.1 A
, pp. 311-318
-
-
Schneider, J.1
Neu, K.2
Grimm, H.3
Velcovsky, H.-G.4
Weisse, G.5
Eigenbrodt, E.6
-
62
-
-
79958103961
-
Pyruvate kinase type M2: A key regulator of the metabolic budget system in tumor cells
-
Mazurek S. Pyruvate kinase type M2: a key regulator of the metabolic budget system in tumor cells. Int. J. Biochem. Cell Biol. 43(7), 969-980 (2011).
-
(2011)
Int. J. Biochem. Cell Biol
, vol.43
, Issue.7
, pp. 969-980
-
-
Mazurek, S.1
-
63
-
-
40749099894
-
Pyruvate kinase M2 is a phosphotyrosine-binding protein
-
Christofk HR, Vander Heiden MG, Wu N et al. Pyruvate kinase M2 is a phosphotyrosine-binding protein. Nature 452, 181 (2008).
-
(2008)
Nature
, vol.452
, pp. 181
-
-
Christofk, H.R.1
Vander Heiden, M.G.2
Wu, N.3
-
64
-
-
77249150369
-
Identification of small molecule inhibitors of pyruvate kinase M2
-
Vander Heiden MG, Christofk HR, Schuman E et al. Identification of small molecule inhibitors of pyruvate kinase M2. Biochem. Pharmacol. 79(8), 1118-1124 (2010).
-
(2010)
Biochem. Pharmacol
, vol.79
, Issue.8
, pp. 1118-1124
-
-
Vander Heiden, M.G.1
Christofk, H.R.2
Schuman, E.3
-
65
-
-
0001601215
-
Effects of 2-deoxyglucose on carbohydrate metabolism: Review of the literature and studies in the rat
-
Brown J. Effects of 2-deoxyglucose on carbohydrate metabolism: review of the literature and studies in the rat. Metab. Clin. Exp. 11, 1098-1112 (1962).
-
(1962)
Metab. Clin. Exp
, vol.11
, pp. 1098-1112
-
-
Brown, J.1
-
66
-
-
79952708088
-
Exploring a glycolytic inhibitor for the treatment of an FH-deficient type-2 papillary RCC
-
Yamasaki T, Tran TA, Oz OK et al. Exploring a glycolytic inhibitor for the treatment of an FH-deficient type-2 papillary RCC. Nat. Rev. Urol. 8(3), 165-171 (2011).
-
(2011)
Nat. Rev. Urol
, vol.8
, Issue.3
, pp. 165-171
-
-
Yamasaki, T.1
Tran, T.A.2
Oz, O.K.3
-
67
-
-
42249111525
-
2-Deoxyglucose induces Akt phosphorylation via a mechanism independent of LKB1/AMP-activated protein kinase signaling activation or glycolysis inhibition
-
DOI 10.1158/1535-7163.MCT-07-0559
-
Zhong D, Liu X, Schafer-Hales K et al. 2-Deoxyglucose induces Akt phosphorylation via a mechanism independent of LKB1/AMP-activated protein kinase signaling activation or glycolysis inhibition. Mol. Cancer Ther. 7(4), 809-817 (2008). (Pubitemid 351551034)
-
(2008)
Molecular Cancer Therapeutics
, vol.7
, Issue.4
, pp. 809-817
-
-
Zhong, D.1
Liu, X.2
Schafer-Hales, K.3
Marcus, A.I.4
Khuri, F.R.5
Sun, S.-Y.6
Zhou, W.7
-
68
-
-
71549171732
-
Opportunities in discovery and delivery of anticancer drugs targeting mitochondria and cancer cell metabolism
-
Pathania D, Millard M, Neamati N. Opportunities in discovery and delivery of anticancer drugs targeting mitochondria and cancer cell metabolism. Adv. Drug Deliv. Rev. 61(14), 1250-1275 (2009).
-
(2009)
Adv. Drug Deliv. Rev
, vol.61
, Issue.14
, pp. 1250-1275
-
-
Pathania, D.1
Millard, M.2
Neamati, N.3
-
69
-
-
33744783432
-
Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance
-
DOI 10.1016/j.ccr.2006.04.023, PII S1535610806001450
-
Fantin VR, St-Pierre J, Leder P. Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance. Cancer Cell 9(6), 425-434 (2006). (Pubitemid 43832190)
-
(2006)
Cancer Cell
, vol.9
, Issue.6
, pp. 425-434
-
-
Fantin, V.R.1
St-Pierre, J.2
Leder, P.3
-
70
-
-
66449103009
-
LDH-A inhibition, a therapeutic strategy for treatment of hereditary leiomyomatosis and renal cell cancer
-
Xie H, Valera VA, Merino MJ et al. LDH-A inhibition, a therapeutic strategy for treatment of hereditary leiomyomatosis and renal cell cancer. Mol. Cancer Ther. 8(3), 626-635 (2009).
-
(2009)
Mol. Cancer Ther
, vol.8
, Issue.3
, pp. 626-635
-
-
Xie, H.1
Valera, V.A.2
Merino, M.J.3
-
71
-
-
37449034854
-
Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis
-
DeBerardinis RJ, Mancuso A, Daikhin E et al. Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis. Proc. Natl Acad. Sci. USA 104(49), 19345-19350 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, Issue.49
, pp. 19345-19350
-
-
Deberardinis, R.J.1
Mancuso, A.2
Daikhin, E.3
-
72
-
-
80052580351
-
Hem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase
-
Frezza C, Zheng L, Folger O et al. Hem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase. Nature 477(7363), 225-228 (2011).
-
(2011)
Nature
, vol.477
, Issue.7363
, pp. 225-228
-
-
Frezza, C.1
Zheng, L.2
Folger, O.3
-
73
-
-
84855987831
-
Reductive carboxylation supports growth in tumour cells with defective mitochondria
-
Mullen AR, Wheaton WW, Jin ES et al. Reductive carboxylation supports growth in tumour cells with defective mitochondria. Nature 481(7381), 385-388 (2012).
-
(2012)
Nature
, vol.481
, Issue.7381
, pp. 385-388
-
-
Mullen, A.R.1
Wheaton, W.W.2
Jin, E.S.3
-
74
-
-
57749088701
-
Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction
-
Wise DR, DeBerardinis RJ, Mancuso A et al. Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction. Proc. Natl Acad. Sci. USA 105(48), 18782-18787 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, Issue.48
, pp. 18782-18787
-
-
Wise, D.R.1
Deberardinis, R.J.2
Mancuso, A.3
-
75
-
-
77957937428
-
Targeting mitochondrial glutaminase activity inhibits oncogenic transformation
-
Wang JB, Erickson JW, Fuji R et al. Targeting mitochondrial glutaminase activity inhibits oncogenic transformation. Cancer Cell 18(3), 207-219 (2010).
-
(2010)
Cancer Cell
, vol.18
, Issue.3
, pp. 207-219
-
-
Wang, J.B.1
Erickson, J.W.2
Fuji, R.3
-
76
-
-
78549283855
-
Inhibition of glutaminase preferentially slows growth of glioma cells with mutant IDH1
-
Seltzer MJ, Bennett BD, Joshi AD et al. Inhibition of glutaminase preferentially slows growth of glioma cells with mutant IDH1. Cancer Res. 70(22), 8981-8987 (2010).
-
(2010)
Cancer Res
, vol.70
, Issue.22
, pp. 8981-8987
-
-
Seltzer, M.J.1
Bennett, B.D.2
Joshi, A.D.3
-
77
-
-
79957774646
-
Pyruvate carboxylase is required for glutamine-independent growth of tumor cells
-
Cheng T, Sudderth J, Yang C et al. Pyruvate carboxylase is required for glutamine-independent growth of tumor cells. Proc. Natl Acad. Sci. USA 108(21), 8674-8679 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, Issue.21
, pp. 8674-8679
-
-
Cheng, T.1
Sudderth, J.2
Yang, C.3
-
78
-
-
18844386435
-
Histologic predictors of renal cell carcinoma response to interleukin-2-based therapy
-
Upton MP, Parker RA, Youmans A et al. Histologic predictors of renal cell carcinoma response to interleukin-2-based therapy. J. Immunother. 28, 488-495 (2005). (Pubitemid 41232570)
-
(2005)
Journal of Immunotherapy
, vol.28
, Issue.5
, pp. 488-495
-
-
Upton, M.P.1
Parker, R.A.2
Youmans, A.3
McDermott, D.F.4
Atkins, M.B.5
-
79
-
-
0036569472
-
Treatment outcome and survival associated with metastatic renal cell carcinoma of non-clear-cell histology
-
DOI 10.1200/JCO.2002.11.123
-
Motzer RJ, Bacik J, Mariani T, Russo P, Mazumdar M, Reuter V. Treatment outcome and survival associated with metastatic renal cell carcinoma of non-clear cell histology. J. Clin. Oncol. 20(9), 2376-2381 (2002). (Pubitemid 34441667)
-
(2002)
Journal of Clinical Oncology
, vol.20
, Issue.9
, pp. 2376-2381
-
-
Motzer, R.J.1
Bacik, J.2
Mariani, T.3
Russo, P.4
Mazumdar, M.5
Reuter, V.6
-
80
-
-
79952707246
-
Sunitinib in papillary renal cell carcinoma (pRCC): Results from a single-arm Phase II study
-
Plimack E, Jonasch E, Bekele B et al. Sunitinib in papillary renal cell carcinoma (pRCC): results from a single-arm Phase II study. J. Clin. Oncol. 28, 15s (2010).
-
(2010)
J. Clin. Oncol
, vol.28
-
-
Plimack, E.1
Jonasch, E.2
Bekele, B.3
-
81
-
-
57049150525
-
Encouraging survival with erlotinib in advanced papillary renal cell carcinoma (pRCC): Final results from Southwest Oncology Group study 0317
-
Abstract 5051
-
Pan C, Hussey M, Lara P et al. Encouraging survival with erlotinib in advanced papillary renal cell carcinoma (pRCC): final results from Southwest Oncology Group study 0317. J. Clin. Oncol. 26, Abstract 5051 (2008).
-
(2008)
J. Clin. Oncol
, vol.26
-
-
Pan, C.1
Hussey, M.2
Lara, P.3
-
82
-
-
30944452354
-
Treatment of metastatic renal cell carcinoma with a combination of bevacizumab and erlotinib
-
DOI 10.1200/JCO.2005.01.8234
-
Hainsworth JD, Sosman JA, Spigel DR, Edwards DL, Baughman C, Greco A. Treatment of metastatic renal cell carcinoma with a combination of bevacizumab and erlotinib. J. Clin. Oncol. 23(31), 7889-7896 (2005). (Pubitemid 46657387)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.31
, pp. 7889-7896
-
-
Hainsworth, J.D.1
Sosman, J.A.2
Spigel, D.R.3
Edwards, D.L.4
Baughman, C.5
Greco, A.6
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