Modelling the endothelial blood-CNS barriers: A method for the production of robust in vitro models of the rat blood-brain barrier and blood-spinal cord barrier

BMC Neuroscience

Volumn 14, Issue , 2013, Pages

  Watson, P Marc D ^a   Paterson, Judy C ^a   Thom, George ^a   Ginman, Ulrika ^b   Lundquist, Stefan ^b   Webster, Carl I ^a  

^a MEDIMMUNE   (United States)

^b ASTRAZENECA R AND D   (Sweden)

Author keywords

Blood brain barrier; Blood spinal cord barrier; Drug discovery; FITC dextran; Hydrodynamic radius; in vitro; Lucifer yellow; Permeability coefficient; TEER

Indexed keywords

REAGENT; TIGHT JUNCTION PROTEIN;

ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BLOOD SPINAL CORD BARRIER; BRAIN TISSUE; CONTROLLED STUDY; ELECTRIC RESISTANCE; ENDOTHELIUM CELL; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NONHUMAN; PERMEABILITY BARRIER; PHENOTYPE; PROTEIN EXPRESSION; RAT; SPINAL CORD; WESTERN BLOTTING;

ANIMALS; BLOOD-BRAIN BARRIER; BRAIN; CELLS, CULTURED; CHROMATOGRAPHY, LIQUID; CLAUDIN-5; COCULTURE TECHNIQUES; DEXTRANS; ELECTRIC IMPEDANCE; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; FLUORESCEIN-5-ISOTHIOCYANATE; ISOQUINOLINES; MALE; MASS SPECTROMETRY; MODELS, BIOLOGICAL; NEUROGLIA; P-GLYCOPROTEIN; PERMEABILITY; RATS; RATS, WISTAR; SPINAL CORD;

EID: 84879047058     PISSN: None     EISSN: 14712202     Source Type: Journal    
DOI: 10.1186/1471-2202-14-59     Document Type: Article

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