Validation of in vitro cell culture models of the blood-brain barrier: Tightness characterization of two promising cell lines

Journal of Pharmaceutical Sciences

Volumn 97, Issue 12, 2008, Pages 5158-5175

  Neuhaus, Winfried ^a   Plattner, Verena E ^a   Wirth, Michael ^a   Germann, Bettina ^a   Lachmann, Bodo ^a   Gabor, Franz ^a   Noe, Christian R ^a  

^a UNIVERSITY OF VIENNA   (Austria)

Author keywords

APTS dextran; BBB; Blood brain barrier; Cell layer tightness; Drug transport studies

Indexed keywords

8 AMINOPYRENE 1,3,6 TRISULFONATE; BU 101; DEXTRAN; DIAZEPAM; GLYCINE RECEPTOR ANTAGONIST; GLYCOPROTEIN P; OCCLUDIN; PROTEIN ZO1; PYRENE DERIVATIVE; SULFONIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BLOOD BRAIN BARRIER; CELL CULTURE; CELL MEMBRANE PERMEABILITY; CELL STRAIN CACO 2; CONTROLLED STUDY; DRUG TRANSPORT; ELECTRIC RESISTANCE; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE MICROSCOPY; IN VITRO STUDY; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; TIGHT JUNCTION; TRANSENDOTHELIAL ELECTRICAL RESISTANCE; VALIDATION PROCESS; WESTERN BLOTTING;

EID: 57349107176     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.21371     Document Type: Article

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