-
1
-
-
0022507341
-
Blindness in Saudi Arabia
-
Tabbara KF, Ross-Degnan D. Blindness in Saudi Arabia. JAMA 1986;255:3378-84.
-
(1986)
JAMA
, vol.255
, pp. 3378-3384
-
-
Tabbara, K.F.1
Ross-Degnan, D.2
-
3
-
-
84878780104
-
-
KACST. Available from. [Last accessed on 2012 Dec 18]
-
KACST. Strategic Priorities for Advanced Medical and Health Research, 2-46. Available from: http://www.kacst.edu.sa/en/ research/Documents/ MedicalAndHealth.pdf. [Last accessed on 2012 Dec 18].
-
Strategic Priorities for Advanced Medical and Health Research
, pp. 2-46
-
-
-
4
-
-
84878790998
-
-
KACST. Available from [Last accessed on 2012 Dec 18]
-
KACST. Strategic Priorities for Nanotechnology Program, 2-62. Available from: http://www.kacst.edu.sa/en/research/ Documents/Nanotechnology.pdf. [Last accessed on 2012 Dec 18].
-
Strategic Priorities for Nanotechnology Program
, pp. 2-62
-
-
-
5
-
-
81855170441
-
Nanomedicine(s) under the microscope
-
Duncan R, Gaspar R. Nanomedicine(s) under the microscope. Mol Pharm 2011;8:2101-41.
-
(2011)
Mol Pharm
, vol.8
, pp. 2101-2141
-
-
Duncan, R.1
Gaspar, R.2
-
6
-
-
61849153021
-
Impact of nanotechnology on drug delivery
-
Farokhzad OC, Langer R. Impact of nanotechnology on drug delivery. ACS Nano 2009;3:16-20.
-
(2009)
ACS Nano
, vol.3
, pp. 16-20
-
-
Farokhzad, O.C.1
Langer, R.2
-
7
-
-
77956434412
-
Nanotechnology in drug delivery and tissue engineering: From discovery to applications
-
Shi J, Votruba AR, Farokhzad OC, Langer R. Nanotechnology in drug delivery and tissue engineering: From discovery to applications. Nano Lett 2010;10:3223-30.
-
(2010)
Nano Lett
, vol.10
, pp. 3223-3230
-
-
Shi, J.1
Votruba, A.R.2
Farokhzad, O.C.3
Langer, R.4
-
8
-
-
33947150969
-
Nanostructured materials for applications in drug delivery and tissue engineering
-
Goldberg M, Langer R, Jia X. Nanostructured materials for applications in drug delivery and tissue engineering. J Biomater Sci Polym Ed 2007;18:241-68.
-
(2007)
J Biomater Sci Polym Ed
, vol.18
, pp. 241-268
-
-
Goldberg, M.1
Langer, R.2
Jia, X.3
-
9
-
-
0029347460
-
Liposome ocular delivery systems
-
Meisner D, Mezei M. Liposome ocular delivery systems. Adv Drug Deliv Rev 1995;16:75-93.
-
(1995)
Adv Drug Deliv Rev
, vol.16
, pp. 75-93
-
-
Meisner, D.1
Mezei, M.2
-
10
-
-
35048842305
-
Liposomal drug delivery systems: An update review
-
Samad A, Sultana Y, Aqil M. Liposomal drug delivery systems: An update review. Curr Drug Deliv 2007;4:297-305.
-
(2007)
Curr Drug Deliv
, vol.4
, pp. 297-305
-
-
Samad, A.1
Sultana, Y.2
Aqil, M.3
-
13
-
-
84861031974
-
Liposomes for intravitreal drug delivery: A state of the art
-
Bochot A, Fattal E. Liposomes for intravitreal drug delivery: A state of the art. J Control Release 2012;161:628-34.
-
(2012)
J Control Release
, vol.161
, pp. 628-634
-
-
Bochot, A.1
Fattal, E.2
-
15
-
-
0022534573
-
A preliminary study of corneal penetration of 125I-labelled idoxuridine liposome
-
Dharma SK, Fishman PH, Peyman GA. A preliminary study of corneal penetration of 125I-labelled idoxuridine liposome. Acta Ophthalmol (Copenh) 1986;64:298-301.
-
(1986)
Acta Ophthalmol (Copenh)
, vol.64
, pp. 298-301
-
-
Dharma, S.K.1
Fishman, P.H.2
Peyman, G.A.3
-
16
-
-
0029347475
-
Microspheres and nanoparticles used in ocular delivery systems
-
Zimmer A, Kreuter J. Microspheres and nanoparticles used in ocular delivery systems. Adv Drug Deliv Rev 1995;16:61-73.
-
(1995)
Adv Drug Deliv Rev
, vol.16
, pp. 61-73
-
-
Zimmer, A.1
Kreuter, J.2
-
17
-
-
67349084376
-
Polymeric nanoparticulate system: A potential approach for ocular drug delivery
-
Nagarwal RC, Kant S, Singh PN, Maiti P, Pandit JK. Polymeric nanoparticulate system: A potential approach for ocular drug delivery. J Control Release 2009;136:2-13.
-
(2009)
J Control Release
, vol.136
, pp. 2-13
-
-
Nagarwal, R.C.1
Kant, S.2
Singh, P.N.3
Maiti, P.4
Pandit, J.K.5
-
18
-
-
38349134916
-
Dendrimers as drug carriers: Applications in different routes of drug administration
-
Cheng Y, Xu Z, Ma M, Xu T. Dendrimers as drug carriers: Applications in different routes of drug administration. J Pharm Sci 2008;97:123-43.
-
(2008)
J Pharm Sci
, vol.97
, pp. 123-143
-
-
Cheng, Y.1
Xu, Z.2
Ma, M.3
Xu, T.4
-
19
-
-
84858855701
-
Situ gel systems as 'smart' carriers for sustained ocular drug delivery
-
Agrawal AK, Das M, Jain S. In situ gel systems as 'smart' carriers for sustained ocular drug delivery. Expert Opin Drug Deliv 2012;9:383-402.
-
(2012)
Expert Opin Drug Deliv
, vol.9
, pp. 383-402
-
-
Agrawal, A.K.1
Das, M.2
Jain, S.3
-
21
-
-
26644437438
-
The use of mucoadhesive polymers in ocular drug delivery
-
Ludwig A. The use of mucoadhesive polymers in ocular drug delivery. Adv Drug Deliv Rev 2005;57:1595-639.
-
(2005)
Adv Drug Deliv Rev
, vol.57
, pp. 1595-1639
-
-
Ludwig, A.1
-
23
-
-
0347379787
-
Role of mucins in the function of the corneal and conjunctival epithelia
-
Gipson IK, Argüeso P. Role of mucins in the function of the corneal and conjunctival epithelia. Int Rev Cytol 2003;231: 1-49.
-
(2003)
Int Rev Cytol
, vol.231
, pp. 1-49
-
-
Gipson, I.K.1
Argüeso, P.2
-
24
-
-
79957490620
-
Development and characterization of Cyclosporine A loaded nanoparticles for ocular drug delivery: Cellular toxicity, uptake, and kinetic studies
-
Aksungur P, Demirbilek M, Denkbaş EB, Vandervoort J, Ludwig A, Unlü N. Development and characterization of Cyclosporine A loaded nanoparticles for ocular drug delivery: Cellular toxicity, uptake, and kinetic studies. J Control Release 2011;151:286-94.
-
(2011)
J Control Release
, vol.151
, pp. 286-294
-
-
Aksungur, P.1
Demirbilek, M.2
Denkbaş, E.B.3
Vandervoort, J.4
Ludwig, A.5
Unlü, N.6
-
25
-
-
84864444446
-
Interfacial interaction between transmembrane ocular mucins and adhesive polymers and dendrimers analyzed by surface plasmon resonance
-
Bravo-Osuna I, Noiray M, Briand E, Woodward AM, Argüeso P, Molina Martínez IT, et al. Interfacial interaction between transmembrane ocular mucins and adhesive polymers and dendrimers analyzed by surface plasmon resonance. Pharm Res 2012;29:2329-40.
-
(2012)
Pharm Res
, vol.29
, pp. 2329-2340
-
-
Bravo-Osuna, I.1
Noiray, M.2
Briand, E.3
Woodward, A.M.4
Argüeso, P.5
Molina Martínez, I.T.6
-
26
-
-
77952958803
-
Thiolated quaternary ammonium-chitosan conjugates for enhanced precorneal retention, transcorneal permeation and intraocular absorption of dexamethasone
-
Zambito Y, Di Colo G. Thiolated quaternary ammonium-chitosan conjugates for enhanced precorneal retention, transcorneal permeation and intraocular absorption of dexamethasone. Eur J Pharm Biopharm 2010;75:194-9.
-
(2010)
Eur J Pharm Biopharm
, vol.75
, pp. 194-199
-
-
Zambito, Y.1
Di Colo, G.2
-
27
-
-
78650533463
-
Ocular drug delivery - A look towards nanobioadhesives
-
du Toit LC, Pillay V, Choonara YE, Govender T, Carmichael T. Ocular drug delivery - a look towards nanobioadhesives. Expert Opin Drug Deliv 2011;8:71-94.
-
(2011)
Expert Opin Drug Deliv
, vol.8
, pp. 71-94
-
-
Du Toit, L.C.1
Pillay, V.2
Choonara, Y.E.3
Govender, T.4
Carmichael, T.5
-
28
-
-
63949085738
-
Role of transporters in ocular drug delivery system
-
Mitra AK. Role of transporters in ocular drug delivery system. Pharm Res 2009;26:1192-6.
-
(2009)
Pharm Res
, vol.26
, pp. 1192-1196
-
-
Mitra, A.K.1
-
29
-
-
63849344988
-
Enhanced corneal absorption of erythromycin by modulating P-glycoprotein and MRP mediated efflux with corticosteroids
-
Hariharan S, Gunda S, Mishra GP, Pal D, Mitra AK. Enhanced corneal absorption of erythromycin by modulating P-glycoprotein and MRP mediated efflux with corticosteroids. Pharm Res 2009;26:1270-82.
-
(2009)
Pharm Res
, vol.26
, pp. 1270-1282
-
-
Hariharan, S.1
Gunda, S.2
Mishra, G.P.3
Pal, D.4
Mitra, A.K.5
-
30
-
-
63949087764
-
Transcorneal permeation of L- and D-aspartate ester prodrugs of acyclovir: Delineation of passive diffusion versus transporter involvement
-
Majumdar S, Hingorani T, Srirangam R, Gadepalli RS, Rimoldi JM, Repka MA. Transcorneal permeation of L- and D-aspartate ester prodrugs of acyclovir: Delineation of passive diffusion versus transporter involvement. Pharm Res 2009;26:1261-9.
-
(2009)
Pharm Res
, vol.26
, pp. 1261-1269
-
-
Majumdar, S.1
Hingorani, T.2
Srirangam, R.3
Gadepalli, R.S.4
Rimoldi, J.M.5
Repka, M.A.6
-
31
-
-
44749091428
-
Ocular pharmacokinetics of acyclovir amino acid ester prodrugs in the anterior
-
chamber: Evaluation of their utility in treating ocular HSV infections
-
Katragadda S, Gunda S, Hariharan S, Mitra AK. Ocular pharmacokinetics of acyclovir amino acid ester prodrugs in the anterior chamber: Evaluation of their utility in treating ocular HSV infections. Int J Pharm 2008;359:15-24.
-
(2008)
Int J Pharm
, vol.359
, pp. 15-24
-
-
Katragadda, S.1
Gunda, S.2
Hariharan, S.3
Mitra, A.K.4
-
32
-
-
12444299613
-
Influence of preparation conditions on acyclovir-loaded poly-d,l-lactic acid nanospheres and effect of PEG coating on ocular drug bioavailability
-
Giannavola C, Bucolo C, Maltese A, Paolino D, Vandelli MA, Puglisi G, et al. Influence of preparation conditions on acyclovir-loaded poly-d,l-lactic acid nanospheres and effect of PEG coating on ocular drug bioavailability. Pharm Res 2003;20:584-90.
-
(2003)
Pharm Res
, vol.20
, pp. 584-590
-
-
Giannavola, C.1
Bucolo, C.2
Maltese, A.3
Paolino, D.4
Vandelli, M.A.5
Puglisi, G.6
-
33
-
-
79955026932
-
Ocular sustained release nanoparticles containing stereoisomeric dipeptide prodrugs of acyclovir
-
Jwala J, Boddu SH, Shah S, Sirimulla S, Pal D, Mitra AK. Ocular sustained release nanoparticles containing stereoisomeric dipeptide prodrugs of acyclovir. J Ocul Pharmacol Ther 2011;27:163-72.
-
(2011)
J Ocul Pharmacol Ther
, vol.27
, pp. 163-172
-
-
Jwala, J.1
Boddu, S.H.2
Shah, S.3
Sirimulla, S.4
Pal, D.5
Mitra, A.K.6
-
34
-
-
84855729411
-
Temperature sensitive contact lenses for triggered ophthalmic drug delivery
-
Jung HJ, Chauhan A. Temperature sensitive contact lenses for triggered ophthalmic drug delivery. Biomaterials 2012;33:2289-300.
-
(2012)
Biomaterials
, vol.33
, pp. 2289-2300
-
-
Jung, H.J.1
Chauhan, A.2
-
35
-
-
57649089384
-
Surfactantladen soft contact lenses for extended delivery of ophthalmic drugs
-
Kapoor Y, Thomas JC, Tan G, John VT, Chauhan A. Surfactantladen soft contact lenses for extended delivery of ophthalmic drugs. Biomaterials 2009;30:867-78.
-
(2009)
Biomaterials
, vol.30
, pp. 867-878
-
-
Kapoor, Y.1
Thomas, J.C.2
Tan, G.3
John, V.T.4
Chauhan, A.5
-
36
-
-
84864709178
-
Extended drug delivery by contact lenses for glaucoma therapy
-
Peng CC, Burke MT, Carbia BE, Plummer C, Chauhan A. Extended drug delivery by contact lenses for glaucoma therapy. J Control Release 2012;162:152-8.
-
(2012)
J Control Release
, vol.162
, pp. 152-158
-
-
Peng, C.C.1
Burke, M.T.2
Carbia, B.E.3
Plummer, C.4
Chauhan, A.5
-
37
-
-
80052534766
-
Extended cyclosporine delivery by silicone-hydrogel contact lenses
-
Peng CC, Chauhan A. Extended cyclosporine delivery by silicone-hydrogel contact lenses. J Control Release 2011;154:267-74.
-
(2011)
J Control Release
, vol.154
, pp. 267-274
-
-
Peng, C.C.1
Chauhan, A.2
-
38
-
-
36148962885
-
Zero-order therapeutic release from imprinted hydrogel contact lenses within in vitro physiological ocular tear flow
-
Ali M, Horikawa S, Venkatesh S, Saha J, Hong JW, Byrne ME. Zero-order therapeutic release from imprinted hydrogel contact lenses within in vitro physiological ocular tear flow. J Control Release 2007;124:154-62.
-
(2007)
J Control Release
, vol.124
, pp. 154-162
-
-
Ali, M.1
Horikawa, S.2
Venkatesh, S.3
Saha, J.4
Hong, J.W.5
Byrne, M.E.6
-
39
-
-
60049094848
-
Controlled release of high molecular weight hyaluronic acid from molecularly imprinted hydrogel contact lenses
-
Ali M, Byrne ME. Controlled release of high molecular weight hyaluronic acid from molecularly imprinted hydrogel contact lenses. Pharm Res 2009;26:714-26.
-
(2009)
Pharm Res
, vol.26
, pp. 714-726
-
-
Ali, M.1
Byrne, M.E.2
-
40
-
-
79957897806
-
Extended release of high molecular weight hydroxypropyl methylcellulose from molecularly imprinted, extended wear silicone hydrogel contact lenses
-
White CJ, McBride MK, Pate KM, Tieppo A, Byrne ME. Extended release of high molecular weight hydroxypropyl methylcellulose from molecularly imprinted, extended wear silicone hydrogel contact lenses. Biomaterials 2011;32:5698-705.
-
(2011)
Biomaterials
, vol.32
, pp. 5698-5705
-
-
White, C.J.1
McBride, M.K.2
Pate, K.M.3
Tieppo, A.4
Byrne, M.E.5
-
41
-
-
77952678353
-
Molecularly imprinted therapeutic contact lenses
-
White CJ, Byrne ME. Molecularly imprinted therapeutic contact lenses. Expert Opin Drug Deliv 2010;7:765-80.
-
(2010)
Expert Opin Drug Deliv
, vol.7
, pp. 765-780
-
-
White, C.J.1
Byrne, M.E.2
-
42
-
-
84858013352
-
Exploiting dendrimer multivalency to combat emerging and re-emerging infectious diseases
-
Mintzer MA, Dane EL, O'Toole GA, Grinstaff MW. Exploiting dendrimer multivalency to combat emerging and re-emerging infectious diseases. Mol Pharm 2012;9:342-54.
-
(2012)
Mol Pharm
, vol.9
, pp. 342-354
-
-
Mintzer, M.A.1
Dane, E.L.2
O'Toole, G.A.3
Grinstaff, M.W.4
-
43
-
-
77954315628
-
Inhibition of bacterial growth and intramniotic infection in a guinea pig model of chorioamnionitis using PAMAM dendrimers
-
Wang B, Navath RS, Menjoge AR, Balakrishnan B, Bellair R, Dai H, et al. Inhibition of bacterial growth and intramniotic infection in a guinea pig model of chorioamnionitis using PAMAM dendrimers. Int J Pharm 2010;395:298-308.
-
(2010)
Int J Pharm
, vol.395
, pp. 298-308
-
-
Wang, B.1
Navath, R.S.2
Menjoge, A.R.3
Balakrishnan, B.4
Bellair, R.5
Dai, H.6
-
44
-
-
79961084368
-
Injectable PAMAM dendrimer-PEG hydrogels for the treatment of genital infections: Formulation and in vitro and in vivo evaluation
-
Navath RS, Menjoge AR, Dai H, Romero R, Kannan S, Kannan RM. Injectable PAMAM dendrimer-PEG hydrogels for the treatment of genital infections: Formulation and in vitro and in vivo evaluation. Mol Pharm 2011;8:1209-23.
-
(2011)
Mol Pharm
, vol.8
, pp. 1209-1223
-
-
Navath, R.S.1
Menjoge, A.R.2
Dai, H.3
Romero, R.4
Kannan, S.5
Kannan, R.M.6
-
45
-
-
50549094168
-
Evaluation of toxicity of commercial ophthalmic fluoroquinolone antibiotics as assessed on immortalized corneal and conjunctival epithelial cells
-
Sosa AB, Epstein SP, Asbell PA. Evaluation of toxicity of commercial ophthalmic fluoroquinolone antibiotics as assessed on immortalized corneal and conjunctival epithelial cells. Cornea 2008;27:930-4.
-
(2008)
Cornea
, vol.27
, pp. 930-934
-
-
Sosa, A.B.1
Epstein, S.P.2
Asbell, P.A.3
-
46
-
-
34250219583
-
Polyamidoamine (PAMAM) dendrimers as biocompatible carriers of quinolone antimicrobials: An in vitro study
-
Cheng Y, Qu H, Ma M, Xu Z, Xu P, Fang Y, et al. Polyamidoamine (PAMAM) dendrimers as biocompatible carriers of quinolone antimicrobials: An in vitro study. Eur J Med Chem 2007;42:1032-8.
-
(2007)
Eur J Med Chem
, vol.42
, pp. 1032-1038
-
-
Cheng, Y.1
Qu, H.2
Ma, M.3
Xu, Z.4
Xu, P.5
Fang, Y.6
-
47
-
-
0036234358
-
A photopolymerized sealant for corneal lacerations
-
Miki D, Dastgheib K, Kim T, Pfister-Serres A, Smeds KA, Inoue M, et al. A photopolymerized sealant for corneal lacerations. Cornea 2002;21:393-9.
-
(2002)
Cornea
, vol.21
, pp. 393-399
-
-
Miki, D.1
Dastgheib, K.2
Kim, T.3
Pfister-Serres, A.4
Smeds, K.A.5
Inoue, M.6
-
48
-
-
0035195242
-
Photocrosslinkable polysaccharides for in situ hydrogel formation
-
Smeds KA, Pfister-Serres A, Miki D, Dastgheib K, Inoue M, Hatchell DL, et al. Photocrosslinkable polysaccharides for in situ hydrogel formation. J Biomed Mater Res 2001;54:115-21.
-
(2001)
J Biomed Mater Res
, vol.54
, pp. 115-121
-
-
Smeds, K.A.1
Pfister-Serres, A.2
Miki, D.3
Dastgheib, K.4
Inoue, M.5
Hatchell, D.L.6
-
49
-
-
5644254184
-
Dendritic macromers as in situ polymerizing biomaterials for securing cataract incisions
-
Wathier M, Jung PJ, Carnahan MA, Kim T, Grinstaff MW. Dendritic macromers as in situ polymerizing biomaterials for securing cataract incisions. J Am Chem Soc 2004;126:12744-5.
-
(2004)
J Am Chem Soc
, vol.126
, pp. 12744-12745
-
-
Wathier, M.1
Jung, P.J.2
Carnahan, M.A.3
Kim, T.4
Grinstaff, M.W.5
-
50
-
-
34948840023
-
Designing hydrogel adhesives for corneal wound repair
-
Grinstaff MW. Designing hydrogel adhesives for corneal wound repair. Biomaterials 2007;28:5205-14.
-
(2007)
Biomaterials
, vol.28
, pp. 5205-5214
-
-
Grinstaff, M.W.1
-
51
-
-
34250156685
-
Photo cross-linkable biodendrimers as ophthalmic adhesives for central lacerations and penetrating keratoplasties
-
Degoricija L, Johnson CS, Wathier M, Kim T, Grinstaff MW. Photo cross-linkable biodendrimers as ophthalmic adhesives for central lacerations and penetrating keratoplasties. Invest Ophthalmol Vis Sci 2007;48:2037-42.
-
(2007)
Invest Ophthalmol Vis Sci
, vol.48
, pp. 2037-2042
-
-
Degoricija, L.1
Johnson, C.S.2
Wathier, M.3
Kim, T.4
Grinstaff, M.W.5
-
52
-
-
65249106054
-
Comparison of sutures and dendritic polymer adhesives for corneal laceration repair in an in vivo chicken model
-
Berdahl JP, Johnson CS, Proia AD, Grinstaff MW, Kim T. Comparison of sutures and dendritic polymer adhesives for corneal laceration repair in an in vivo chicken model. Arch Ophthalmol 2009;127:442-7.
-
(2009)
Arch Ophthalmol
, vol.127
, pp. 442-447
-
-
Berdahl, J.P.1
Johnson, C.S.2
Proia, A.D.3
Grinstaff, M.W.4
Kim, T.5
-
53
-
-
36048975465
-
Corneal gene therapy
-
Klausner EA, Peer D, Chapman RL, Multack RF, Andurkar SV. Corneal gene therapy. J Control Release 2007;124:107-33.
-
(2007)
J Control Release
, vol.124
, pp. 107-133
-
-
Klausner, E.A.1
Peer, D.2
Chapman, R.L.3
Multack, R.F.4
Andurkar, S.V.5
-
56
-
-
84861127428
-
Nanoparticle-mediated delivery of shRNA.VEGF-A plasmids regresses corneal neovascularization
-
Qazi Y, Stagg B, Singh N, Singh S, Zhang X, Luo L, et al. Nanoparticle-mediated delivery of shRNA.VEGF-A plasmids regresses corneal neovascularization. Invest Ophthalmol Vis Sci 2012;53:2837-44.
-
(2012)
Invest Ophthalmol Vis Sci
, vol.53
, pp. 2837-2844
-
-
Qazi, Y.1
Stagg, B.2
Singh, N.3
Singh, S.4
Zhang, X.5
Luo, L.6
-
57
-
-
84861157207
-
Flt23k nanoparticles offer additive benefit in graft survival and anti-angiogenic effects when combined with triamcinolone
-
Cho YK, Uehara H, Young JR, Tyagi P, Kompella UB, Zhang X, et al. Flt23k nanoparticles offer additive benefit in graft survival and anti-angiogenic effects when combined with triamcinolone. Invest Ophthalmol Vis Sci 2012;53:2328-36.
-
(2012)
Invest Ophthalmol Vis Sci
, vol.53
, pp. 2328-2336
-
-
Cho, Y.K.1
Uehara, H.2
Young, J.R.3
Tyagi, P.4
Kompella, U.B.5
Zhang, X.6
-
60
-
-
68149137750
-
Inner blood-retinal barrier transporters: Role of retinal drug delivery
-
Hosoya K, Tachikawa M. Inner blood-retinal barrier transporters: Role of retinal drug delivery. Pharm Res 2009;26:2055-65.
-
(2009)
Pharm Res
, vol.26
, pp. 2055-2065
-
-
Hosoya, K.1
Tachikawa, M.2
-
61
-
-
81855209822
-
Strategies for therapy of retinal diseases using systemic drug delivery: Relevance of transporters at the blood-retinal barrier
-
Hosoya K, Tomi M, Tachikawa M. Strategies for therapy of retinal diseases using systemic drug delivery: Relevance of transporters at the blood-retinal barrier. Expert Opin Drug Deliv 2011;8:1571-87.
-
(2011)
Expert Opin Drug Deliv
, vol.8
, pp. 1571-1587
-
-
Hosoya, K.1
Tomi, M.2
Tachikawa, M.3
-
62
-
-
79955022978
-
Ophthalmic drug delivery systems for the treatment of retinal diseases: Basic research to clinical applications
-
Edelhauser HF, Rowe-Rendleman CL, Robinson MR, Dawson DG, Chader GJ, Grossniklaus HE, et al. Ophthalmic drug delivery systems for the treatment of retinal diseases: Basic research to clinical applications. Invest Ophthalmol Vis Sci 2010;51: 5403-20.
-
(2010)
Invest Ophthalmol Vis Sci
, vol.51
, pp. 5403-5420
-
-
Edelhauser, H.F.1
Rowe-Rendleman, C.L.2
Robinson, M.R.3
Dawson, D.G.4
Chader, G.J.5
Grossniklaus, H.E.6
-
63
-
-
0035211330
-
Effect of particle size of polymeric nanospheres on intravitreal kinetics
-
Sakurai E, Ozeki H, Kunou N, Ogura Y. Effect of particle size of polymeric nanospheres on intravitreal kinetics. Ophthalmic Res 2001;33:31-6.
-
(2001)
Ophthalmic Res
, vol.33
, pp. 31-36
-
-
Sakurai, E.1
Ozeki, H.2
Kunou, N.3
Ogura, Y.4
-
64
-
-
77951296547
-
Intravenously administered gold nanoparticles pass through the blood-retinal barrier depending on the particle size, and induce no retinal toxicity
-
Kim JH, Kim JH, Kim KW, Kim MH, Yu YS. Intravenously administered gold nanoparticles pass through the blood-retinal barrier depending on the particle size, and induce no retinal toxicity. Nanotechnology 2009;20:505101.
-
(2009)
Nanotechnology
, vol.20
, pp. 505101
-
-
Kim, J.H.1
Kim, J.H.2
Kim, K.W.3
Kim, M.H.4
Yu, Y.S.5
-
65
-
-
38849152122
-
Effect of circulation on the disposition and ocular tissue distribution of 20 nm nanoparticles after periocular administration
-
Amrite AC, Edelhauser HF, Singh SR, Kompella UB. Effect of circulation on the disposition and ocular tissue distribution of 20 nm nanoparticles after periocular administration. Mol Vis 2008;14:150-60.
-
(2008)
Mol Vis
, vol.14
, pp. 150-160
-
-
Amrite, A.C.1
Edelhauser, H.F.2
Singh, S.R.3
Kompella, U.B.4
-
66
-
-
28644432836
-
Size-dependent disposition of nanoparticles and microparticles following subconjunctival administration
-
Amrite AC, Kompella UB. Size-dependent disposition of nanoparticles and microparticles following subconjunctival administration. J Pharm Pharmacol 2005;57:1555-63.
-
(2005)
J Pharm Pharmacol
, vol.57
, pp. 1555-1563
-
-
Amrite, A.C.1
Kompella, U.B.2
-
67
-
-
58549117281
-
Investigating the movement of intravitreal human serum albumin nanoparticles in the vitreous and retina
-
Kim H, Robinson SB, Csaky KG. Investigating the movement of intravitreal human serum albumin nanoparticles in the vitreous and retina. Pharm Res 2009;26:329-37.
-
(2009)
Pharm Res
, vol.26
, pp. 329-337
-
-
Kim, H.1
Robinson, S.B.2
Csaky, K.G.3
-
68
-
-
84862782522
-
The movement of self-assembled amphiphilic polymeric nanoparticles in the vitreous and retina after intravitreal injection
-
Koo H, Moon H, Han H, Na JH, Huh MS, Park JH, et al. The movement of self-assembled amphiphilic polymeric nanoparticles in the vitreous and retina after intravitreal injection. Biomaterials 2012;33:3485-93.
-
(2012)
Biomaterials
, vol.33
, pp. 3485-3493
-
-
Koo, H.1
Moon, H.2
Han, H.3
Na, J.H.4
Huh, M.S.5
Park, J.H.6
-
69
-
-
32944461193
-
Vitreous: A barrier to nonviral ocular gene therapy
-
Peeters L, Sanders NN, Braeckmans K, Boussery K, Van de Voorde J, De Smedt SC, et al. Vitreous: A barrier to nonviral ocular gene therapy. Invest Ophthalmol Vis Sci 2005;46:3553-61.
-
(2005)
Invest Ophthalmol Vis Sci
, vol.46
, pp. 3553-3561
-
-
Peeters, L.1
Sanders, N.N.2
Braeckmans, K.3
Boussery, K.4
Van De Voorde, J.5
De Smedt, S.C.6
-
70
-
-
34548623989
-
Wanted and unwanted properties of surface PEGylated nucleic acid nanoparticles in ocular gene transfer
-
Sanders NN, Peeters L, Lentacker I, Demeester J, De Smedt SC. Wanted and unwanted properties of surface PEGylated nucleic acid nanoparticles in ocular gene transfer. J Control Release 2007;122:226-35.
-
(2007)
J Control Release
, vol.122
, pp. 226-235
-
-
Sanders, N.N.1
Peeters, L.2
Lentacker, I.3
Demeester, J.4
De Smedt, S.C.5
-
71
-
-
0032937539
-
Reduction of fibronectin expression by intravitreal administration of antisense oligonucleotides
-
Roy S, Zhang K, Roth T, Vinogradov S, Kao RS, Kabanov A. Reduction of fibronectin expression by intravitreal administration of antisense oligonucleotides. Nat Biotechnol 1999;17:476-9.
-
(1999)
Nat Biotechnol
, vol.17
, pp. 476-479
-
-
Roy, S.1
Zhang, K.2
Roth, T.3
Vinogradov, S.4
Kao, R.S.5
Kabanov, A.6
-
72
-
-
84864119719
-
Influence of choroidal neovascularization and biodegradable polymeric particle size on transscleral sustained delivery of triamcinolone acetonide
-
Kadam RS, Tyagi P, Edelhauser HF, Kompella UB. Influence of choroidal neovascularization and biodegradable polymeric particle size on transscleral sustained delivery of triamcinolone acetonide. Int J Pharm 2012;434:140-7.
-
(2012)
Int J Pharm
, vol.434
, pp. 140-147
-
-
Kadam, R.S.1
Tyagi, P.2
Edelhauser, H.F.3
Kompella, U.B.4
-
73
-
-
79955045075
-
Influence of drug solubility and lipophilicity on transscleral retinal delivery of six corticosteroids
-
Thakur A, Kadam RS, Kompella UB. Influence of drug solubility and lipophilicity on transscleral retinal delivery of six corticosteroids. Drug Metab Dispos 2011;39:771-81.
-
(2011)
Drug Metab Dispos
, vol.39
, pp. 771-781
-
-
Thakur, A.1
Kadam, R.S.2
Kompella, U.B.3
-
74
-
-
70349290518
-
Subconjunctivally implantable hydrogels with degradable and thermoresponsive properties for sustained release of insulin to the retina
-
Misra GP, Singh RS, Aleman TS, Jacobson SG, Gardner TW, Lowe TL. Subconjunctivally implantable hydrogels with degradable and thermoresponsive properties for sustained release of insulin to the retina. Biomaterials 2009;30:6541-7.
-
(2009)
Biomaterials
, vol.30
, pp. 6541-6547
-
-
Misra, G.P.1
Singh, R.S.2
Aleman, T.S.3
Jacobson, S.G.4
Gardner, T.W.5
Lowe, T.L.6
-
75
-
-
0042844771
-
Ocular drug delivery targeting the retina and retinal pigment epithelium using polylactide nanoparticles
-
Bourges JL, Gautier SE, Delie F, Bejjani RA, Jeanny JC, Gurny R, et al. Ocular drug delivery targeting the retina and retinal pigment epithelium using polylactide nanoparticles. Invest Ophthalmol Vis Sci 2003;44:3562-9.
-
(2003)
Invest Ophthalmol Vis Sci
, vol.44
, pp. 3562-3569
-
-
Bourges, J.L.1
Gautier, S.E.2
Delie, F.3
Bejjani, R.A.4
Jeanny, J.C.5
Gurny, R.6
-
76
-
-
84862989504
-
Intravitreal poly(l-lactide) microparticles sustain retinal and choroidal delivery of tg-0054, a hydrophilic drug intended for neovascular diseases
-
Shelke NB, Kadam R, Tyagi P, Rao VR, Kompella UB. Intravitreal Poly(L-lactide) Microparticles Sustain Retinal and Choroidal Delivery of TG-0054, a Hydrophilic Drug Intended for Neovascular Diseases. Drug Deliv Transl Res 2011;1:76-90.
-
(2011)
Drug Deliv Transl Res
, vol.1
, pp. 76-90
-
-
Shelke, N.B.1
Kadam, R.2
Tyagi, P.3
Rao, V.R.4
Kompella, U.B.5
-
77
-
-
36549039554
-
Pharmacokinetics of intravitreal ranibizumab (Lucentis)
-
Bakri SJ, Snyder MR, Reid JM, Pulido JS, Ezzat MK, Singh RJ. Pharmacokinetics of intravitreal ranibizumab (Lucentis). Ophthalmology 2007;114:2179-82.
-
(2007)
Ophthalmology
, vol.114
, pp. 2179-2182
-
-
Bakri, S.J.1
Snyder, M.R.2
Reid, J.M.3
Pulido, J.S.4
Ezzat, M.K.5
Singh, R.J.6
-
78
-
-
13944266313
-
Preclinical pharmacokinetics of Ranibizumab (rhuFabV2) after a single intravitreal administration
-
Gaudreault J, Fei D, Rusit J, Suboc P, Shiu V. Preclinical pharmacokinetics of Ranibizumab (rhuFabV2) after a single intravitreal administration. Invest Ophthalmol Vis Sci 2005;46:726-33.
-
(2005)
Invest Ophthalmol Vis Sci
, vol.46
, pp. 726-733
-
-
Gaudreault, J.1
Fei, D.2
Rusit, J.3
Suboc, P.4
Shiu, V.5
-
79
-
-
0033637620
-
Intravitreal pharmacokinetics of plain and liposome-entrapped fluconazole in rabbit eyes
-
Gupta SK, Velpandian T, Dhingra N, Jaiswal J. Intravitreal pharmacokinetics of plain and liposome-entrapped fluconazole in rabbit eyes. J Ocul Pharmacol Ther 2000;16:511-8.
-
(2000)
J Ocul Pharmacol Ther
, vol.16
, pp. 511-518
-
-
Gupta, S.K.1
Velpandian, T.2
Dhingra, N.3
Jaiswal, J.4
-
80
-
-
79959809653
-
Nanospheres delivering the EGFR TKI AG1478 promote optic nerve regeneration: The role of size for intraocular drug delivery
-
Robinson R, Viviano SR, Criscione JM, Williams CA, Jun L, Tsai JC, et al. Nanospheres delivering the EGFR TKI AG1478 promote optic nerve regeneration: The role of size for intraocular drug delivery. ACS Nano 2011;5:4392-400.
-
(2011)
ACS Nano
, vol.5
, pp. 4392-4400
-
-
Robinson, R.1
Viviano, S.R.2
Criscione, J.M.3
Williams, C.A.4
Jun, L.5
Tsai, J.C.6
-
81
-
-
58149085196
-
-
patent application US 2011/0034422 A1; Regular patents filed in US (#12/681 ,516), Canada (#2,701, 291) European Union (#08835693.6), Japan (#2010e528216) and India (1247/ ELNP/2010). 02/10/2011
-
Kannan R, Iezzi R, Kannan S, Guru B, inventors; Dendrimercontaining particles for sustained release of compounds. patent application US 2011/0034422 A1; Regular patents filed in US (#12/681,516), Canada (#2,701,291), European Union (#08835693.6), Japan (#2010e528216) and India (1247/ ELNP/2010). 02/10/2011.
-
Inventors; Dendrimercontaining particles for sustained release of compounds
-
-
Kannan, R.1
Iezzi, R.2
Kannan, S.3
Guru, B.4
-
82
-
-
81155152766
-
Dendrimer-based targeted intravitreal therapy for sustained attenuation of neuroinflammation in retinal degeneration
-
Iezzi R, Guru BR, Glybina IV, Mishra MK, Kennedy A, Kannan RM. Dendrimer-based targeted intravitreal therapy for sustained attenuation of neuroinflammation in retinal degeneration. Biomaterials 2012;33:979-88.
-
(2012)
Biomaterials
, vol.33
, pp. 979-988
-
-
Iezzi, R.1
Guru, B.R.2
Glybina, I.V.3
Mishra, M.K.4
Kennedy, A.5
Kannan, R.M.6
-
83
-
-
84860129964
-
Dendrimer-based postnatal therapy for neuroinflammation and cerebral palsy in a rabbit model
-
130ra46
-
Kannan S, Dai H, Navath RS, Balakrishnan B, Jyoti A, Janisse J, et al. Dendrimer-based postnatal therapy for neuroinflammation and cerebral palsy in a rabbit model. Sci Transl Med 2012;4:130ra46.
-
(2012)
Sci Transl Med
, vol.4
-
-
Kannan, S.1
Dai, H.2
Navath, R.S.3
Balakrishnan, B.4
Jyoti, A.5
Janisse, J.6
-
84
-
-
77954620685
-
Nanoparticles for retinal gene therapy
-
Conley SM, Naash MI. Nanoparticles for retinal gene therapy. Prog Retin Eye Res 2010;29:376-97.
-
(2010)
Prog Retin Eye Res
, vol.29
, pp. 376-397
-
-
Conley, S.M.1
Naash, M.I.2
-
85
-
-
77951632478
-
Gene delivery to mitotic and postmitotic photoreceptors via compacted DNA nanoparticles results in improved phenotype in a mouse model of retinitis pigmentosa
-
Cai X, Conley SM, Nash Z, Fliesler SJ, Cooper MJ, Naash MI. Gene delivery to mitotic and postmitotic photoreceptors via compacted DNA nanoparticles results in improved phenotype in a mouse model of retinitis pigmentosa. FASEB J 2010;24:1178-91.
-
(2010)
FASEB J
, vol.24
, pp. 1178-1191
-
-
Cai, X.1
Conley, S.M.2
Nash, Z.3
Fliesler, S.J.4
Cooper, M.J.5
Naash, M.I.6
-
86
-
-
65449178420
-
A partial structural and functional rescue of a retinitis pigmentosa model with compacted DNA nanoparticles
-
Cai X, Nash Z, Conley SM, Fliesler SJ, Cooper MJ, Naash MI. A partial structural and functional rescue of a retinitis pigmentosa model with compacted DNA nanoparticles. PLoS One 2009;4:e5290.
-
(2009)
PLoS One
, vol.4
-
-
Cai, X.1
Nash, Z.2
Conley, S.M.3
Fliesler, S.J.4
Cooper, M.J.5
Naash, M.I.6
-
87
-
-
70350733741
-
Ocular delivery of compacted DNA-nanoparticles does not elicit toxicity in the mouse retina
-
Ding XQ, Quiambao AB, Fitzgerald JB, Cooper MJ, Conley SM, Naash MI. Ocular delivery of compacted DNA-nanoparticles does not elicit toxicity in the mouse retina. PLoS One 2009;4:e7410.
-
(2009)
PLoS One
, vol.4
-
-
Ding, X.Q.1
Quiambao, A.B.2
Fitzgerald, J.B.3
Cooper, M.J.4
Conley, S.M.5
Naash, M.I.6
-
88
-
-
84855846254
-
Highly compacted DNA nanoparticles with low MW PEG coatings In vitro, ex vivo and in vivo evaluation
-
Boylan NJ, Suk JS, Lai SK, Jelinek R, Boyle MP, Cooper MJ, et al. Highly compacted DNA nanoparticles with low MW PEG coatings: In vitro, ex vivo and in vivo evaluation. J Control Release 2012;157:72-9.
-
(2012)
J Control Release
, vol.157
, pp. 72-79
-
-
Boylan, N.J.1
Suk, J.S.2
Lai, S.K.3
Jelinek, R.4
Boyle, M.P.5
Cooper, M.J.6
-
89
-
-
80053588027
-
Nanoparticlemediated gene transfer specific to retinal pigment epithelial cells
-
Koirala A, Makkia RS, Cooper MJ, Naash MI. Nanoparticlemediated gene transfer specific to retinal pigment epithelial cells. Biomaterials 2011;32:9483-93.
-
(2011)
Biomaterials
, vol.32
, pp. 9483-9493
-
-
Koirala, A.1
Makkia, R.S.2
Cooper, M.J.3
Naash, M.I.4
-
90
-
-
80054737042
-
Size-selective and in vitro assessment of inner blood retina barrier permeability
-
Campbell M, Humphries P. Size-selective and in vitro assessment of inner blood retina barrier permeability. Methods Mol Biol 2011;763:355-67.
-
(2011)
Methods Mol Biol
, vol.763
, pp. 355-367
-
-
Campbell, M.1
Humphries, P.2
-
91
-
-
77953832373
-
Systemic delivery of therapeutics to neuronal tissues: A barrier modulation approach
-
Campbell M, Ozaki E, Humphries P. Systemic delivery of therapeutics to neuronal tissues: A barrier modulation approach. Expert Opin Drug Deliv 2010;7:859-69.
-
(2010)
Expert Opin Drug Deliv
, vol.7
, pp. 859-869
-
-
Campbell, M.1
Ozaki, E.2
Humphries, P.3
-
92
-
-
70449577160
-
An experimental platform for systemic drug delivery to the retina
-
Campbell M, Nguyen AT, Kiang AS, Tam LC, Gobbo OL, Kerskens C, et al. An experimental platform for systemic drug delivery to the retina. Proc Natl Acad Sci U S A 2009;106:17817-22.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 17817-17822
-
-
Campbell, M.1
Nguyen, A.T.2
Kiang, A.S.3
Tam, L.C.4
Gobbo, O.L.5
Kerskens, C.6
-
93
-
-
67349119829
-
Intravenous transferrin, RGD peptide and dualtargeted nanoparticles enhance anti-VEGF intraceptor gene delivery to laser-induced CNV
-
Singh SR, Grossniklaus HE, Kang SJ, Edelhauser HF, Ambati BK, Kompella UB. Intravenous transferrin, RGD peptide and dualtargeted nanoparticles enhance anti-VEGF intraceptor gene delivery to laser-induced CNV. Gene Ther 2009;16:645-59.
-
(2009)
Gene Ther
, vol.16
, pp. 645-659
-
-
Singh, S.R.1
Grossniklaus, H.E.2
Kang, S.J.3
Edelhauser, H.F.4
Ambati, B.K.5
Kompella, U.B.6
-
94
-
-
55949127631
-
Ocular nanoparticle toxicity and transfection of the retina and retinal pigment epithelium
-
Prow TW, Bhutto I, Kim SY, Grebe R, Merges C, McLeod DS, et al. Ocular nanoparticle toxicity and transfection of the retina and retinal pigment epithelium. Nanomedicine 2008;4:340-9.
-
(2008)
Nanomedicine
, vol.4
, pp. 340-349
-
-
Prow, T.W.1
Bhutto, I.2
Kim, S.Y.3
Grebe, R.4
Merges, C.5
McLeod, D.S.6
-
95
-
-
79957557933
-
Evaluation of magnetic micro- and nanoparticle toxicity to ocular tissues
-
Raju HB, Hu Y, Vedula A, Dubovy SR, Goldberg JL. Evaluation of magnetic micro- and nanoparticle toxicity to ocular tissues. PLoS One 2011;6:e17452.
-
(2011)
PLoS One
, vol.6
-
-
Raju, H.B.1
Hu, Y.2
Vedula, A.3
Dubovy, S.R.4
Goldberg, J.L.5
-
96
-
-
27544499791
-
Dendrimer delivery of an anti-VEGF oligonucleotide into the eye: A long-term study into inhibition of laser-induced CNV, distribution, uptake and toxicity
-
Marano RJ, Toth I, Wimmer N, Brankov M, Rakoczy PE. Dendrimer delivery of an anti-VEGF oligonucleotide into the eye: A long-term study into inhibition of laser-induced CNV, distribution, uptake and toxicity. Gene Ther 2005;12:1544-50.
-
(2005)
Gene Ther
, vol.12
, pp. 1544-1550
-
-
Marano, R.J.1
Toth, I.2
Wimmer, N.3
Brankov, M.4
Rakoczy, P.E.5
-
97
-
-
84863225073
-
Ophthalmic drug discovery: Novel targets and mechanisms for retinal diseases and glaucoma
-
Zhang K, Zhang L, Weinreb RN. Ophthalmic drug discovery: Novel targets and mechanisms for retinal diseases and glaucoma. Nat Rev Drug Discov 2012;11:541-59.
-
(2012)
Nat Rev Drug Discov
, vol.11
, pp. 541-559
-
-
Zhang, K.1
Zhang, L.2
Weinreb, R.N.3
-
98
-
-
82555185076
-
The renaissance of drug delivery systems for the posterior segment
-
Shapiro A, Lazar E. The renaissance of drug delivery systems for the posterior segment. Retina Today 2011:22-5.
-
(2011)
Retina Today
, pp. 22-25
-
-
Shapiro, A.1
Lazar, E.2
|