Strategies for therapy of retinal diseases using systemic drug delivery: Relevance of transporters at the bloodretinal barrier

Expert Opinion on Drug Delivery

Volumn 8, Issue 12, 2011, Pages 1571-1587

  Hosoya, Ken Ichi ^a   Tomi, Masatoshi ^b   Tachikawa, Masanori ^c  

^a UNIVERSITY OF TOYAMA   (Japan)

^b KEIO UNIVERSITY   (Japan)

^c TOHOKU UNIVERSITY   (Japan)

Author keywords

ABC transporters; Drug delivery; Inner bloodretinal barrier; Outer bloodretinal barrier; Retina; SLC transporters

Indexed keywords

ABC TRANSPORTER; AMINO ACID TRANSPORTER; CATION; FOLIC ACID DERIVATIVE; GLUCOSE TRANSPORTER 1; MONOCARBOXYLATE TRANSPORTER; NUCLEOSIDE; VERAPAMIL;

BLOOD RETINA BARRIER; CHOROID CAPILLARY LAYER; DRUG DELIVERY SYSTEM; DRUG PENETRATION; DRUG TRANSPORT; DRUG UPTAKE; ENDOTHELIUM CELL; GLUCOSE TRANSPORT; HUMAN; HYDROPHILICITY; LIPOPHILICITY; MEMBRANE PERMEABILITY; MICRODIALYSIS; PIGMENT EPITHELIUM; RETINA CAPILLARY; RETINA DISEASE; RETINAL CAPILLARY ENDOTHELIAL CELL; REVIEW;

ANIMALS; BLOOD-RETINAL BARRIER; DRUG ADMINISTRATION ROUTES; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MEMBRANE TRANSPORT PROTEINS; PERMEABILITY; RETINAL DISEASES;

EID: 81855209822     PISSN: 17425247     EISSN: 17447593     Source Type: Journal    
DOI: 10.1517/17425247.2011.628983     Document Type: Review

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