Structure-activity relationship for (+)-taxifolin isolated from silymarin as an inhibitor of amyloid β aggregation

Bioscience, Biotechnology and Biochemistry

Volumn 77, Issue 5, 2013, Pages 1100-1103

  Sato, Mizuho ^a   Murakami, Kazuma ^a   Uno, Mayumi ^a   Ikubo, Haruko ^a   Nakagawa, Yu ^a,b   Katayama, Sumie ^c   Akagi, Ken Ichi ^c   Irie, Kazuhiro ^a  

^a KYOTO UNIVERSITY   (Japan)

^b RIKEN   (Japan)

^c NATIONAL INSTITUTE OF BIOMEDICAL INNOVATION   (Japan)

Author keywords

(+) taxifolin; Aggregation; Alzheimer's disease; Amyloid ; Silymarin

Indexed keywords

ALZHEIMER'S; ALZHEIMER'S DISEASE; IN-VIVO; SILYMARIN; STRUCTURE ACTIVITY RELATIONSHIPS; TAXIFOLIN;

AGGLOMERATION; FLAVONOIDS; GLYCOPROTEINS; STEREOCHEMISTRY;

PLANTS (BOTANY);

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN (1 42); AMYLOID BETA-PROTEIN (1-42); DRUG DERIVATIVE; PEPTIDE FRAGMENT; QUERCETIN; SILYMARIN; TAXIFOLIN;

ARTICLE; CHEMISTRY; DRUG EFFECT; ISOLATION AND PURIFICATION; PROTEIN MULTIMERIZATION; PROTEIN SECONDARY STRUCTURE; STRUCTURE ACTIVITY RELATION;

AMYLOID BETA-PEPTIDES; PEPTIDE FRAGMENTS; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, SECONDARY; QUERCETIN; SILYMARIN; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84878713270     PISSN: 09168451     EISSN: 13476947     Source Type: Journal    
DOI: 10.1271/bbb.120925     Document Type: Article

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