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Volumn 42, Issue 24, 2013, Pages 8907-8917
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Chiral ruthenium(ii) complexes with phenolic hydroxyl groups as dual poisons of topoisomerases i and IIα
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Author keywords
[No Author keywords available]
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Indexed keywords
CAMPTOTHECIN (CPT);
CANCER THERAPY;
CELL-CYCLE PROGRESSION;
CELLULAR LEVELS;
INDUCED APOPTOSIS;
PHENOLIC HYDROXYL GROUP;
POTENT INHIBITOR;
RUTHENIUM COMPLEXES;
CELL DEATH;
CELL PROLIFERATION;
RUTHENIUM;
SYNTHESIS (CHEMICAL);
RUTHENIUM COMPOUNDS;
CAMPTOTHECIN;
DNA;
DNA TOPOISOMERASE;
DNA TOPOISOMERASE (ATP HYDROLYSING);
DNA TOPOISOMERASE INHIBITOR;
ETOPOSIDE;
GYRASE INHIBITOR;
RUTHENIUM;
APOPTOSIS;
ARTICLE;
CELL CYCLE;
CELL NUCLEUS;
CELL PROLIFERATION;
CHEMISTRY;
COMET ASSAY;
DNA DAMAGE;
DRUG DESIGN;
DRUG SCREENING;
HUMAN;
IC 50;
METABOLISM;
METHODOLOGY;
PROTEIN BINDING;
TUMOR CELL LINE;
APOPTOSIS;
CAMPTOTHECIN;
CELL CYCLE;
CELL LINE, TUMOR;
CELL NUCLEUS;
CELL PROLIFERATION;
CHEMISTRY, PHARMACEUTICAL;
COMET ASSAY;
DNA;
DNA DAMAGE;
DNA TOPOISOMERASES, TYPE I;
DNA TOPOISOMERASES, TYPE II;
DRUG DESIGN;
DRUG SCREENING ASSAYS, ANTITUMOR;
ETOPOSIDE;
HUMANS;
INHIBITORY CONCENTRATION 50;
PROTEIN BINDING;
RUTHENIUM;
TOPOISOMERASE I INHIBITORS;
TOPOISOMERASE II INHIBITORS;
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EID: 84878664932
PISSN: 14779226
EISSN: 14779234
Source Type: Journal
DOI: 10.1039/c3dt50472g Document Type: Article |
Times cited : (40)
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References (50)
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