Mechanism of cytotoxicity of copper(I) complexes of 1,2- bis(diphenylphosphino) ethane

Journal of Medicinal Chemistry

Volumn 48, Issue 4, 2005, Pages 977-985

  Sanghamitra, Nusrat J ^a   Phatak, Pornima ^a   Das, Sanjeev ^a   Samuelson, Ashoka G ^a   Somasundaram, Kumaravel ^a  

^a INDIAN INSTITUTE OF SCIENCE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

1,2 BIS(DIPHENYLPHOSPHINO)ETHANE COPPER COMPLEX; ANTINEOPLASTIC AGENT; COPPER COMPLEX; DOXORUBICIN; PHOSPHINE DERIVATIVE; PROTEIN P53; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL CYCLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; DRUG DNA BINDING; DRUG MECHANISM; DRUG POTENTIATION; DRUG SYNTHESIS; FLOW CYTOMETRY; GROWTH INHIBITION; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; LUNG CARCINOMA; SIMULATION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; COPPER; DNA; DNA DAMAGE; DOXORUBICIN; DRUG SCREENING ASSAYS, ANTITUMOR; DRUG SYNERGISM; HUMANS; MODELS, MOLECULAR; ORGANOMETALLIC COMPOUNDS; ORGANOPHOSPHORUS COMPOUNDS; PHOSPHINES; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR SUPPRESSOR PROTEIN P53;

EID: 13944249461     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm049430g     Document Type: Article

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